_EC 3.1.4.1 Phosphodiesterase I. 6 PDB entries  
EC 3.-.-.- Hydrolases. [21,051 PDB entries]
EC 3.1.-.- Acting on ester bonds. [5,973 PDB entries]
EC 3.1.4.- Phosphoric diester hydrolases. [452 PDB entries]
EC 3.1.4.1 Phosphodiesterase I. [6 PDB entries]    
2ys0

Reaction: Hydrolytically removes 5'-nucleotides successively from the 3'-hydroxy termini of 3'-hydroxy-terminated oligonucleotides.
Other name(s): 5' nucleotide phosphodiesterase/alkaline phosphodiesterase I. 5'-exonuclease. 5'-NPDase. 5'-nucleotide phosphodiesterase. 5'-PDase. 5'-PDE. 5'-phosphodiesterase. 5'Npde. Alkaline phosphodiesterase. Exonuclease I.
Comments: Hydrolyzes both ribonucleotides and deoxyribonucleotides. Has low activity toward polynucleotides. A 3'-phosphate terminus on the substrate inhibits hydrolysis.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 6 PDB entries in enzyme class E.C.3.1.4.1

  PDB code Protein
2ys0
Solution structure of the somatomedin b domain of human ectonucleotide pyrophosphatase/phosphodiesterase family member
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: enpp1. Other_details: cell-free protein synthesis
Chain: A (56 residues) CATH domain: Unassigned
4b56
Structure of ectonucleotide pyrophosphatase-phosphodiesteras (npp1)
Source: Mus musculus. Mouse. Organism_taxid: 10090. Expressed in: homo sapiens. Expression_system_taxid: 9606. Expression_system_cell_line: hek293s gnti
Chains: A, B (816 residues) CATH domains: Unassigned Unassigned Unassigned
4gtw
Crystal structure of mouse enpp1 in complex with amp
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: enpp2, npps2, pdnp2, enpp1, mcg_9001.
Chains: A, B (706 residues) CATH domains: Unassigned Unassigned
Bound ligand:   Het Group AMP is 41.67% similar to enzyme product 1-alkyl-sn-glycero-3-phosphate
4gtx
Crystal structure of mouse enpp1 in complex with tmp
Source: Mus musculus. E. Organism_taxid: 10090. Cell: mammalian cells. Gene: enpp2, npps2, pdnp2, enpp1, mcg_9001.
Chains: A, B (706 residues) CATH domains: Unassigned Unassigned
Bound ligand:   Het Group TMP is 45.45% similar to enzyme product 1-alkyl-sn-glycero-3-phosphate
4gty
Crystal structure of mouse enpp1 in complex with gmp
Source: Mus musculus. Organism_taxid: 10090. Cell: mammalian cells. Gene: enpp2, npps2, pdnp2, enpp1, mcg_9001.
Chains: A, B (706 residues) CATH domains: Unassigned Unassigned
Bound ligand:   Het Group 5GP is 40.00% similar to enzyme product 1-alkyl-sn-glycero-3-phosphate
4gtz
Crystal structure of mouse enpp1 in complex with cmp
Source: Mus musculus. Organism_taxid: 10090. Gene: enpp2, npps2, pdnp2, enpp1, mcg_9001. Expression_system_cell: mammalian cells.
Chains: A, B (706 residues) CATH domains: Unassigned Unassigned
Bound ligand:   Het Group C5P is 45.45% similar to enzyme product 1-alkyl-sn-glycero-3-phosphate