_EC 3.1.3.3 Phosphoserine phosphatase. 42 PDB entries  
EC 3.-.-.- Hydrolases. [21,057 PDB entries]
EC 3.1.-.- Acting on ester bonds. [5,979 PDB entries]
EC 3.1.3.- Phosphoric monoester hydrolases. [1,340 PDB entries]
EC 3.1.3.3 Phosphoserine phosphatase. [42 PDB entries]    
1f5s

Reaction: O-phospho-L(or D)-serine + H(2)O = L(or D)-serine + phosphate.
 

O-phospho-L(or D)-serine
+ H(2)O
= L(or D)-serine
+
phosphate
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 42 PDB entries in enzyme class E.C.3.1.3.3

  PDB code Protein
1f5s
Crystal structure of phosphoserine phosphatase from methanococcus jannaschii
Source: Methanocaldococcus jannaschii. Organism_taxid: 2190. Strain: mj1594. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (210 residues) CATH domains: 3.40.50.1000 1.10.150.210
Bound ligand:   Het Group PO4 corresponds to enzyme product phosphate
1j97
Phospho-aspartyl intermediate analogue of phosphoserine phosphatase
Source: Methanocaldococcus jannaschii. Organism_taxid: 2190. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (210 residues) CATH domains: 3.40.50.1000 1.10.150.210
Bound ligand:   Het Group PO4 corresponds to enzyme product phosphate
1l7m
High resolution liganded structure of phosphoserine phosphatase (pi complex)
Source: Methanocaldococcus jannaschii. Organism_taxid: 2190. Gene: mj1594. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (209 residues) CATH domains: 3.40.50.1000 1.10.150.210
Bound ligand:   Het Group PO4 corresponds to enzyme product phosphate
1l7n
Transition state analogue of phosphoserine phosphatase (aluminum fluoride complex)
Source: Methanocaldococcus jannaschii. Organism_taxid: 2190. Gene: mj1594. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (209 residues) CATH domains: 3.40.50.1000 1.10.150.210
1l7o
Crystal structure of phosphoserine phosphatase in apo form
Source: Methanocaldococcus jannaschii. Organism_taxid: 2190. Gene: mj1594. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (200 residues) CATH domains: 3.40.50.1000 1.10.150.210
1l7p
Substrate bound phosphoserine phosphatase complex structure
Source: Methanocaldococcus jannaschii. Organism_taxid: 2190. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (208 residues) CATH domains: 3.40.50.1000 1.10.150.210
Bound ligand:   Het Group PO4 corresponds to enzyme product phosphate
1l8l
Molecular basis for the local confomational rearrangement of human phosphoserine phosphatase
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (222 residues) CATH domains: 3.40.50.1000 1.10.150.210
1l8o
Molecular basis for the local conformational rearrangement of human phosphoserine phosphatase
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (222 residues) CATH domains: 3.40.50.1000 1.10.150.210
Bound ligand:   Het Group PO4 corresponds to enzyme product phosphate
1nnl
Crystal structure of human phosphoserine phosphatase
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (205 residues) CATH domains: 3.40.50.1000 1.10.150.210
1rku
Crystal structure of thrh gene product of pseudomonas aerugi
Source: Pseudomonas aeruginosa. Organism_taxid: 208964. Strain: pao1. Gene: thrh. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (206 residues) CATH domains: 3.40.50.1000 3.90.1470.10
1rkv
Structure of phosphate complex of thrh from pseudomonas aeru
Source: Pseudomonas aeruginosa. Organism_taxid: 208964. Strain: pao1. Gene: thrh. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (206 residues) CATH domains: 3.40.50.1000 3.90.1470.10
1w24
Crystal structure of human vps29
Source: Homo sapiens. Human. Organism_taxid: 9606. Organ: brain. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (180 residues) CATH domain: 3.60.21.10
1w53
Kinase recruitment domain of the stress phosphatase rsbu
Source: Bacillus subtilis. Organism_taxid: 1423. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (84 residues) CATH domain: 1.10.1240.30
1z2w
Crystal structure of mouse vps29 complexed with mn2+
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: vps29. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (182 residues) CATH domain: 3.60.21.10
1z2x
Crystal structure of mouse vps29
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: vps29. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (182 residues) CATH domain: 3.60.21.10
2cfr
Crystal structure of human pyridoxal 5'-phosphate phosphatase
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chain: A (290 residues) CATH domains: 3.40.50.1000 3.40.50.1000
2cfs
Crystal structure of human pyridoxal 5'-phosphate phosphatase
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chain: A (293 residues) CATH domains: 3.40.50.1000 3.40.50.1000
2cft
Crystal structure of human pyridoxal 5'-phosphate phosphatase with its substrate
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chain: A (293 residues) CATH domains: 3.40.50.1000 3.40.50.1000
Bound ligand:   Het Group PLP corresponds to enzyme reactant pyridoxal 5'-phosphate
2j6y
Structural and functional characterisation of partner switching regulating the environmental stress response in bacillus subtilis
Source: Bacillus subtilis. Organism_taxid: 1423. Expressed in: escherichia coli. Expression_system_taxid: 511693. Expression_system_variant: de3.
Chains: A, B, C, D, E (85 residues) CATH domain: 1.10.1240.30
2j6z
Structural and functional characterisation of partner- switching regulating the environmental stress response in b. Subtilis
Source: Bacillus subtilis. Organism_taxid: 1423. Expressed in: escherichia coli. Expression_system_taxid: 511693. Expression_system_variant: de3.
Chain: A (86 residues) CATH domain: 1.10.1240.30
2j70
Structural and functional characterisation of partner- switching regulating the environmental stress response in b. Subtilis
Source: Bacillus subtilis. Organism_taxid: 1423. Expressed in: escherichia coli. Expression_system_taxid: 511693. Expression_system_variant: de3.
Chain: A (83 residues) CATH domain: 1.10.1240.30
2oyc
Crystal structure of human pyridoxal phosphate phosphatase
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: pdxp, plp, plpp. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (292 residues) CATH domains: 3.40.50.1000 3.40.50.1000
2p27
Crystal structure of human pyridoxal phosphate phosphatase with mg2+ at 1.9 a resolution
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: pdxp, plp, plpp. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (289 residues) CATH domains: 3.40.50.1000 3.40.50.1000
2p69
Crystal structure of human pyridoxal phosphate phosphatase w
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: pdxp, plp, plpp. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (288 residues) CATH domains: 3.40.50.1000 3.40.50.1000
Bound ligand:   Het Group PLP corresponds to enzyme reactant pyridoxal
2r17
Functional architecture of the retromer cargo-recognition co
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: vps29. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Gene: vps35, mem3.
Chains: A, B (183 residues) CATH domain: 3.60.21.10
3lh6
Crystal structure of mouse vps29 complexed with zn2+
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: vps29. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (182 residues) CATH domain: 3.60.21.10
3lh7
Crystal structure of mouse vps29 complexed with mn2+
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: vps29. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (182 residues) CATH domain: 3.60.21.10
3p96
Crystal structure of phosphoserine phosphatase serb from myc avium, native form
Source: Mycobacterium avium. Organism_taxid: 243243. Strain: 104. Gene: serb, mav_3907. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (396 residues) CATH domain: 3.30.70.260
3psn
Crystal structure of mouse vps29 complexed with mn2+
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: vps29. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (183 residues) CATH domain: 3.60.21.10
3pso
Crystal structure of mouse vps29 complexed with zn2+
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: vps29. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (182 residues) CATH domain: 3.60.21.10
3w40
Crystal structure of rsbx in complex with magnesium in space
Source: Bacillus subtilis. Organism_taxid: 224308. Strain: 168. Gene: bsu04740, rsbx. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (199 residues) CATH domain: Unassigned
3w41
Crystal structure of rsbx in complex with magnesium in space
Source: Bacillus subtilis. Organism_taxid: 224308. Strain: 168. Gene: bsu04740, rsbx. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (199 residues) CATH domain: Unassigned
3w42
Crystal structure of rsbx in complex with manganese in space
Source: Bacillus subtilis. Organism_taxid: 224308. Strain: 168. Gene: bsu04740, rsbx. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (199 residues) CATH domain: Unassigned
3w43
Crystal structure of rsbx in complex with manganese in space
Source: Bacillus subtilis. Organism_taxid: 224308. Strain: 168. Gene: bsu04740, rsbx. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (199 residues) CATH domain: Unassigned
3w44
Crystal structure of rsbx, selenomethionine derivative
Source: Bacillus subtilis. Organism_taxid: 224308. Strain: 168. Gene: bsu04740, rsbx. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (199 residues) CATH domain: Unassigned
3w45
Crystal structure of rsbx in complex with cobalt in space gr
Source: Bacillus subtilis. Organism_taxid: 224308. Strain: 168. Gene: bsu04740, rsbx. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (199 residues) CATH domain: Unassigned
4bkm
Crystal structure of the murine aum (phosphoglycolate phosph capping domain as a fusion protein with the catalytic core domain of murine chronophin (pyridoxal phosphate phosphatas
Source: Mus musculus, mus musculus, mus muscul house mouse, house mouse, house mouse. Organism_taxid: 10090, 10090, 10090. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D (304 residues) CATH domains: 3.40.50.1000 3.40.50.1000
4bx0
Crystal structure of a monomeric variant of murine chronophin (pyridoxal phosphate phosphatase)
Source: Mus musculus. House mouse. Organism_taxid: 10090. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (287 residues) CATH domains: 3.40.50.1000 3.40.50.1000
4bx2
Crystal structure of murine chronophin (pyridoxal phosphate phosphatase) in complex with beryllium trifluoride
Source: Mus musculus. House mouse. Organism_taxid: 10090. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (292 residues) CATH domains: 3.40.50.1000 3.40.50.1000
4bx3
Crystal structure of murine chronophin (pyridoxal phosphate phosphatase)
Source: Mus musculus. House mouse. Organism_taxid: 10090. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (291 residues) CATH domains: 3.40.50.1000 3.40.50.1000
4ij5
Crystal structure of a novel-type phosphoserine phosphatase hydrogenobacter thermophilus tk-6
Source: Hydrogenobacter thermophilus. Organism_taxid: 608538. Strain: dsm 6534 / iam 12695 / tk-6. Gene: pspa, pgma, hth_0103, hydth_0104. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (211 residues) CATH domain: 3.40.50.1240
4ij6
Crystal structure of a novel-type phosphoserine phosphatase (h9a) from hydrogenobacter thermophilus tk-6 in comp l-phosphoserine
Source: Hydrogenobacter thermophilus. Organism_taxid: 608538. Strain: dsm 6534 / iam 12695 / tk-6. Gene: pspa, pgma, hth_0103, hydth_0104. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (207 residues) CATH domain: 3.40.50.1240
Bound ligand:   Het Group SEP is 45.45% similar to enzyme product phosphate