_EC 3.1.3.2 Acid phosphatase. 36 PDB entries  
EC 3.-.-.- Hydrolases. [8,019 PDB entries]
EC 3.1.-.- Acting on ester bonds. [2,193 PDB entries]
EC 3.1.3.- Phosphoric monoester hydrolases. [483 PDB entries]
EC 3.1.3.2 Acid phosphatase. [36 PDB entries]    
1d1p

Reaction: A phosphate monoester + H(2)O = an alcohol + phosphate.
 


phosphate monoester
+ H(2)O
=
alcohol
+
phosphate
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): Acid phosphomonoesterase. Glycerophosphatase. Phosphomonoesterase.
Comments: Wide specificity. Also catalyzes transphosphorylations.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 36 PDB entries in enzyme class E.C.3.1.3.2

  PDB code Protein
1d1p
Crystal structure of a yeast low molecular weight protein tyrosine phosphatase (ltp1)
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (156 residues) CATH domain: 3.40.50.2300
1dkp
Crystal structure of phytate complex of escherichia coli phytase at ph 6.6. Phytate is bound with its 3-phosphate in the active site. Hg2+ cation acts as an intermolecular bridge
Source: Escherichia coli. Organism_taxid: 562. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (410 residues) CATH domains: 3.40.50.1240 3.40.50.1240
1nd6
Crystal structures of human prostatic acid phosphatase in co a phosphate ion and alpha-benzylaminobenzylphosphonic acid mechanistic picture and offer new insights into inhibitor d
Source: Homo sapiens. Human. Organism_taxid: 9606. Tissue: semen
Chains: A, B, C, D (342 residues) CATH domain: 3.40.50.1240
Bound ligand:   Het Group PO4 corresponds to enzyme product phosphate
1phr
The crystal structure of a low molecular phosphotyrosine protein phosphatase
Source: Bos taurus. Cattle. Organism_taxid: 9913
Chain: A (154 residues) CATH domain: 3.40.50.2300
1rm7
Crystal structure of apha class b acid phosphatase/phosphotransferase ternary complex with adenosine and phosphate at 2 a resolution
Source: Escherichia coli. Bacteria. Gene: apha, napa, b4055, sf4149, s3580. Expressed in: escherichia coli.
Chains: A, C (211 residues) CATH domain: 3.40.50.1000
1rmw
Crystal structure of apha class b acid phosphatase/phosphotransferase ternary complex with adenosine and phosphate bound to the catalytic metal at 1.2 a resolution
Source: Escherichia coli. Bacteria. Gene: apha, napa, b4055, sf4149, s3580. Expressed in: escherichia coli.
Chains: A, B (211 residues) CATH domain: 3.40.50.1000
1rpa
Three-dimensional structure of rat acid phosphatase in compl l(+) tartrate
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116
Chain: A (342 residues) CATH domain: 3.40.50.1240
1war
Recombinant human purple acid phosphatase expressed in pichia pastoris
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: pichia pastoris. Expression_system_taxid: 4922.
Chain: A (310 residues) CATH domain: 3.60.21.10
Bound ligand:   Het Group PO4 corresponds to enzyme product phosphate
1z5u
Crystal structure of s. Typhimurium apha complexed with cyclic-amp
Source: Salmonella typhimurium. Organism_taxid: 602. Gene: apha. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B, C, D (208 residues) CATH domain: 3.40.50.1000
2a96
Crystal structure of phosphate tethered phon of s. Typhimurium
Source: Salmonella typhimurium. Organism_taxid: 602. Gene: phon. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (217 residues) CATH domain: 1.20.144.10
2akc
Crystal structure of tungstate complex of the phon protein from s. Typhimurium
Source: Salmonella typhimurium. Organism_taxid: 602. Gene: phon. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, D (218 residues) CATH domain: 1.20.144.10
2b82
Crystal structure of apha class b acid phosphatase/phosphotr ternary complex with adenosine and phosphate bound to thE C metal at 1.2 a resolution
Source: Escherichia coli. Organism_taxid: 562. Gene: apha, napa. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (211 residues) CATH domain: 3.40.50.1000
Bound ligand:   Het Group PO4 corresponds to enzyme product phosphate
2gla
Structure of francisella tularensis histidine acid phosphatase bound to l-(+)-tartaric acid
Source: Francisella tularensis subsp. Holarctica. Organism_taxid: 119857. Strain: live vaccine strain (lvs). Gene: hap. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (329 residues) CATH domain: 3.40.50.1240
2glb
Structure of francisella tularensis histidine acid phosphatase bound to acetate
Source: Francisella tularensis subsp. Holarctica. Organism_taxid: 119857. Strain: live vaccine strain (lvs). Gene: hap. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (327 residues) CATH domain: 3.40.50.1240
2glc
Structure of francisella tularensis histidine acid phosphatase bound to orthovanadate
Source: Francisella tularensis subsp. Holarctica. Organism_taxid: 119857. Strain: live vaccine strain (lvs). Gene: hap. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (327 residues) CATH domain: 3.40.50.1240
2heg
Phospho-aspartyl intermediate analogue of apha class b acid phosphatase/phosphotransferase
Source: Escherichia coli. Organism_taxid: 562. Gene: apha, napa. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (211 residues) CATH domain: 3.40.50.1000
2hlk
Structure of recombinant haemophilus influenzae e(p4) acid phosphatase
Source: Haemophilus influenzae 86-028np. Strain: 86-028np. Gene: hel. Expressed in: escherichia coli
Chain: A (244 residues) CATH domain: Unassigned
2hll
Structure of recombinant haemophilus influenzae e(p4) acid phosphatase complexed with tungstate
Source: Haemophilus influenzae 86-028np. Strain: 86-028np. Gene: hel. Expressed in: escherichia coli
Chain: A (244 residues) CATH domain: Unassigned
2l3h
Nmr structure in a membrane environment reveals putative amy regions of the sevi precursor peptide pap248-286
Source: Synthetic: yes. Homo sapiens. Human. Organism_taxid: 9606. Other_details: acpp
Chain: A (39 residues)
2l77
Solution nmr structure of pap248-286 in 50% tfe
Source: Synthetic: yes. Homo sapiens. Human. Organism_taxid: 9606. Other_details: purchased from from a vendor
Chain: A (39 residues)
2mg0
Pap262-270 in sds micelles
Source: Synthetic: yes. Homo sapiens. Human. Organism_taxid: 9606
Chain: A (11 residues)
2p36
Structure of francisella tularensis histidine acid phosphatase bound to 2r,3r tartranilic acid
Source: Francisella tularensis subsp. Holarctica lvs. Organism_taxid: 376619. Strain: lvs. Gene: hap. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (327 residues) CATH domain: 3.40.50.1240
2p4u
Crystal structure of acid phosphatase 1 (acp1) from mus musculus
Source: Mus musculus. House mouse. Organism_taxid: 10090. Strain: fvb/n. Gene: acp1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B, C (153 residues) CATH domain: 3.40.50.2300
2qfr
Crystal structure of red kidney bean purple acid phosphatase bound sulfate
Source: Phaseolus vulgaris. Kidney bean. Organism_taxid: 3885
Chain: B ( residues)
3cz4
Native apha class b acid phosphatase/phosphotransferase from e. Coli
Source: Escherichia coli. Organism_taxid: 83333. Strain: k12. Gene: apha, napa, yjbp, b4055, jw4015. Expressed in: escherichia coli.
Chain: A (209 residues) CATH domain: 3.40.50.1000
3et4
Structure of recombinant haemophilus influenzae e(p4) acid p
Source: Haemophilus influenzae. Organism_taxid: 281310. Strain: 86-028np. Gene: hel, nthi0816. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (244 residues) CATH domain: Unassigned
3it0
Crystal structure francisella tularensis histidine acid phos complexed with phosphate
Source: Francisella tularensis subsp. Holarcti organism_taxid: 376619. Strain: lvs. Gene: ftl_0031. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: B ( residues)
Bound ligand:   Het Group PO4 corresponds to enzyme product phosphate
3it1
Crystal structure francisella tularensis histidine acid phos complexed with l(+)-tartrate
Source: Francisella tularensis subsp. Holarcti organism_taxid: 376619. Strain: lvs. Gene: ftl_0031. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (328 residues) CATH domain: 3.40.50.1240
3kbp
Kidney bean purple acid phosphatase
Source: Phaseolus vulgaris. Organism_taxid: 3885
Chains: A, B, C, D (424 residues) CATH domains: 2.60.40.380 3.60.21.10
3n8i
Crystal structure of the a isoform of human cytoplasmic prot tyrosine phosphatase (hcptp-a) in complex with 1-naphtylace
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: acp1, apc1. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (154 residues) CATH domain: 3.40.50.2300
3zk4
Structure of purple acid phosphatase ppd1 isolated from yellow lupin (lupinus luteus) seeds
Source: Lupinus luteus. Yellow lupin. Organism_taxid: 3873
Chains: A, B, C (569 residues)
Bound ligand:   Het Group PO4 corresponds to enzyme product phosphate
4e3w
Crystal structure francisella tularensis histidine acid phos cryoprotected with proline
Source: Francisella tularensis subsp. Holarcti organism_taxid: 376619. Strain: lvs. Gene: ftl_0031. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (329 residues) CATH domain: 3.40.50.1240
4job
Crystal structure of human lysophosphatidic acid phosphatase complexed with l-(+)-tartrate
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: acp6. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (369 residues) CATH domain: 3.40.50.1240
4jod
Crystal structure of human lysophosphatidic acid phosphatase complexed with tris
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: acp6. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (378 residues) CATH domain: 3.40.50.1240
4kbp
Kidney bean purple acid phosphatase
Source: Phaseolus vulgaris. Organism_taxid: 3885
Chains: A, B, C, D (424 residues) CATH domains: 2.60.40.380 3.60.21.10
Bound ligand:   Het Group PO4 corresponds to enzyme product phosphate
5pnt
Crystal structure of a human low molecular weight phosphotyrosyl phosphatase. Implications for substrate specificity
Source: Homo sapiens. Human. Organism_taxid: 9606. Cellular_location: cytosol. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chain: A (157 residues) CATH domain: 3.40.50.2300