_EC 3.1.21.3 Type I site-specific deoxyribonuclease. 5 PDB entries  
EC 3.-.-.- Hydrolases. [21,057 PDB entries]
EC 3.1.-.- Acting on ester bonds. [5,979 PDB entries]
EC 3.1.21.- Endodeoxyribonucleases producing 5'-phosphomonoesters. [141 PDB entries]
EC 3.1.21.3 Type I site-specific deoxyribonuclease. [5 PDB entries]    
2w74

Reaction: Endonucleolytic cleavage of Dna to give random double-stranded fragments with terminal 5'-phosphates; Atp is simultaneously hydrolyzed.
Other name(s): Type I restriction enzyme.
Comments: Large group of enzymes that have an absolute requirement for Atp (or dATP) and S-adenosyl-L-methionine. They recognize specific short Dna sequences and cleave at sites remote from the recognition sequence. Multifunctional proteins which also catalyze the reactions of Ec 2.1.1.72 and Ec 2.1.1.73, with similar site specificity. Formerly Ec 3.1.24.1 and Ec 3.1.24.2. See the Rebase database for a complete list of these enzymes: http://rebase.neb.com/rebase/
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 5 PDB entries in enzyme class E.C.3.1.21.3

  PDB code Protein
2w74
Mutant (k220r) of the hsdr subunit of the ecor124i restriction enzyme in complex with atp
Source: Escherichia coli. Organism_taxid: 562. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: B, D (771 residues) CATH domains: Unassigned Unassigned Unassigned Unassigned Unassigned
2y3t
Mutant (k220e) of the hsdr subunit of the ecor124i restricti enzyme in complex with atp
Source: Escherichia coli. Organism_taxid: 562. Expressed in: escherichia coli. Expression_system_taxid: 83333. Expression_system_variant: jm109(de3)
Chains: A, B, C, D (811 residues) CATH domains: Unassigned Unassigned Unassigned Unassigned Unassigned Unassigned
4be7
Mutant (k220r) of the hsdr subunit of the ecor124i restricti enzyme in complex with atp
Source: Escherichia coli. Organism_taxid: 562. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: B, D (837 residues) CATH domains: Unassigned Unassigned Unassigned Unassigned Unassigned Unassigned
4beb
Mutant (k220e) of the hsdr subunit of the ecor124i restriction enzyme in complex with atp
Source: Escherichia coli. Organism_taxid: 562. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D (839 residues) CATH domains: Unassigned Unassigned Unassigned Unassigned Unassigned Unassigned
4bec
Mutant (k220a) of the hsdr subunit of the ecor124i restriction enzyme in complex with atp
Source: Escherichia coli. Organism_taxid: 562. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (845 residues) CATH domains: Unassigned Unassigned Unassigned Unassigned Unassigned Unassigned