_EC 2.8.2.20 Protein-tyrosine sulfotransferase. 3 PDB entries  
EC 2.-.-.- Transferases. [18,993 PDB entries]
EC 2.8.-.- Transferring sulfur-containing groups. [215 PDB entries]
EC 2.8.2.- Sulfotransferases. [53 PDB entries]
EC 2.8.2.20 Protein-tyrosine sulfotransferase. [3 PDB entries]    
3ap1

Reaction: 3'-phosphoadenylyl sulfate + protein tyrosine = adenosine 3',5'-bisphosphate + protein tyrosine-O-sulfate.
 


3'-phosphoadenylyl sulfate
+
protein tyrosine
=
adenosine 3',5'-bisphosphate
+
protein tyrosine-O-sulfate
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): Tyrosylprotein sulfotransferase.
Comments: The tyrosine residues of some specific proteins of rat pheochromocytoma cells act as acceptors. Formerly Ec 2.8.2.n1.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 3 PDB entries in enzyme class E.C.2.8.2.20

  PDB code Protein
3ap1
Crystal structure of human tyrosylprotein sulfotransferase-2 with pap and c4 peptide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: tpst2. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: chemical synthesis
Chains: A, B (298 residues) CATH domain: Unassigned
Bound ligands:   Het Group TYR is 70.59% similar to enzyme reactant [protein]-L-tyrosine
  Het Group A3P corresponds to enzyme product Adenosine
3ap2
Crystal structure of human tyrosylprotein sulfotransferase-2 with pap,c4 peptide, and phosphate ion
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: tpst2. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: chemical synthesis
Chains: A, B (300 residues) CATH domain: Unassigned
Bound ligands:   Het Group TYR is 70.59% similar to enzyme reactant [protein]-L-tyrosine
  Het Group A3P corresponds to enzyme product Adenosine
3ap3
Crystal structure of human tyrosylprotein sulfotransferase-2 with pap
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: tpst2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (282 residues) CATH domain: Unassigned
Bound ligand:   Het Group A3P corresponds to enzyme product Adenosine