_EC 2.7.2.8 Acetylglutamate kinase. 26 PDB entries  
EC 2.-.-.- Transferases. [17,943 PDB entries]
EC 2.7.-.- Transferring phosphorous-containing groups. [10,910 PDB entries]
EC 2.7.2.- Phosphotransferases with a carboxyl group as acceptor. [138 PDB entries]
EC 2.7.2.8 Acetylglutamate kinase. [26 PDB entries]    
1gs5

Pathway: Ornithine Biosynthesis
Reaction: Atp + N-acetyl-L-glutamate = adp + N-acetyl-L-glutamate 5-phosphate.
 


ATP
+
N-acetyl-L-glutamate
=
ADP
+
N-acetyl-L-glutamate 5-phosphate
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 26 PDB entries in enzyme class E.C.2.7.2.8

  PDB code Protein
1gs5
N-acetyl-l-glutamate kinase from escherichia coli complexed with its substrate n-acetylglutamate and its substrate analog amppnp
Source: Escherichia coli. Organism_taxid: 469008. Strain: bl21(de3). Expressed in: escherichia coli. Expression_system_taxid: 469008. Other_details: novagen
Chain: A (258 residues) CATH domain: 3.40.1160.10
Bound ligands:   Het Group NLG corresponds to enzyme reactant N-acetyl-L-glutamate
  Het Group ANP is 81.25% similar to enzyme product ADP
1gsj
Selenomethionine substituted n-acetyl-l-glutamate kinase from escherichia coli complexed with its substrate n-acetyl-l-glutamate and its substrate analog amppnp
Source: Escherichia coli. Organism_taxid: 562. Strain: bl21 (de3). Expressed in: escherichia coli. Expression_system_taxid: 562. Other_details: from novagen
Chain: A (258 residues) CATH domain: 3.40.1160.10
Bound ligands:   Het Group NLG corresponds to enzyme reactant N-acetyl-L-glutamate
  Het Group ANP is 81.00% similar to enzyme product ADP
1oh9
Acetylglutamate kinase from escherichia coli complexed with mgadp, n-acetyl-l-glutamate and the transition-state mimic alf4-
Source: Escherichia coli. Organism_taxid: 562. Strain: bl21(de3). Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (258 residues) CATH domain: 3.40.1160.10
Bound ligands:   Het Group NLG corresponds to enzyme reactant N-acetyl-L-glutamate
  Het Group ADP corresponds to enzyme product ADP
1oha
Acetylglutamate kinase from escherichia coli complexed with mgadp and n-acetyl-l-glutamate
Source: Escherichia coli. Organism_taxid: 562. Strain: bl21(de3). Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (258 residues) CATH domain: 3.40.1160.10
Bound ligands:   Het Group NLG corresponds to enzyme reactant N-acetyl-L-glutamate
  Het Group ADP corresponds to enzyme product ADP
1ohb
Acetylglutamate kinase from escherichia coli complexed with adp and sulphate
Source: Escherichia coli. Organism_taxid: 562. Strain: bl21(de3). Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (258 residues) CATH domain: 3.40.1160.10
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
1uvd
Arginine feed-back inhibitable acetylglutamate kinase
Source: Pseudomonas aeruginosa. Expressed in: escherichia coli.
Chains: A, B, C, D, E, F, G, H, I, J, K, L (300 residues) CATH domain: 3.40.1160.10
Bound ligands:   Het Group ADP is 87.00% similar to enzyme reactant ATP
  Het Group NLG corresponds to enzyme reactant N-acetyl-L-glutamate
1uvv
Acetylglutamate kinase from thermotoga maritima complexed with its inhibitor arginine
Source: Thermotoga maritima. Expressed in: escherichia coli.
Chains: A, B, C (282 residues) CATH domain: 3.40.1160.10
Bound ligand:   Het Group NLG is 85.00% similar to enzyme reactant N-acetyl-L-glutamate
2ap9
Crystal structure of acetylglutamate kinase from mycobacteri tuberculosis cdc1551
Source: Mycobacterium tuberculosis. Organism_taxid: 83331. Strain: cdc1551. Gene: argb, rv1654, mt1692. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D, E, F (299 residues) CATH domain: 3.40.1160.10
2bty
Acetylglutamate kinase from thermotoga maritima complexed with its inhibitor arginine
Source: Thermotoga maritima. Organism_taxid: 2336. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C (282 residues) CATH domain: 3.40.1160.10
Bound ligand:   Het Group NLG corresponds to enzyme reactant N-acetyl-L-glutamate
2buf
Arginine feed-back inhibitable acetylglutamate kinase
Source: Pseudomonas aeruginosa. Organism_taxid: 287. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D, E, F, G, H, I, J, K, L (292 residues) CATH domain: 3.40.1160.10
Bound ligands:   Het Group NLG corresponds to enzyme reactant N-acetyl-L-glutamate
  Het Group ADP corresponds to enzyme product ADP
2jj4
The complex of pii and acetylglutamate kinase from synechococcus elongatus pcc7942
Source: Synechococcus elongatus. Organism_taxid: 1140. Strain: pcc 7942. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chains: A, B, C (284 residues) CATH domain: 3.40.1160.10
Bound ligand:   Het Group NLG corresponds to enzyme reactant N-acetyl-L-glutamate
2rd5
Structural basis for the regulation of n-acetylglutamate kin in arabidopsis thaliana
Source: Arabidopsis thaliana. Thale cress. Organism_taxid: 3702. Gene: t8h10.160. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: at4g01900, t7b11.16.
Chains: A, B (281 residues) CATH domain: 3.40.1160.10
Bound ligands:   Het Group ATP corresponds to enzyme reactant ATP
  Het Group NLG corresponds to enzyme reactant N-acetyl-L-glutamate
  Het Group ADP corresponds to enzyme product ADP
2v5h
Controlling the storage of nitrogen as arginine: the complex of pii and acetylglutamate kinase from synechococcus elongatus pcc 7942
Source: Synechococcus elongatus. Organism_taxid: 1140. Strain: pcc 7942. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chains: A, B, C, D, E, F (284 residues) CATH domain: 3.40.1160.10
Bound ligand:   Het Group NLG corresponds to enzyme reactant N-acetyl-L-glutamate
2wxb
Acetylglutamate kinase from escherichia coli free of substrates
Source: Escherichia coli. Organism_taxid: 469008. Strain: bl21(de3). Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (257 residues) CATH domain: 3.40.1160.10
2x2w
Acetylglutamate kinase from escherichia coli bound to n- acetyl-l-glutamyl-5-phosphate
Source: Escherichia coli. Organism_taxid: 469008. Strain: bl21(de3). Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (258 residues) CATH domain: 3.40.1160.10
Bound ligand:   Het Group X2W corresponds to enzyme product N-acetyl-L-glutamate
3l86
The crystal structure of smu.665 from streptococcus mutans u
Source: Streptococcus mutans. Organism_taxid: 210007. Strain: ua159. Gene: smu.665. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (245 residues) CATH domain: 3.40.1160.10
Bound ligands:   Het Group NLG corresponds to enzyme reactant N-acetyl-L-glutamate
  Het Group ADP corresponds to enzyme product ADP
3s6g
Crystal structures of seleno-substituted mutant mmnags in sp p212121
Source: Maricaulis maris. Organism_taxid: 394221. Strain: mcs10. Gene: arga/b, mmar10_0365. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, X, Y (436 residues) CATH domains: 3.40.1160.10 3.40.630.30
3s6h
Crystal structure of native mmnags/k
Source: Maricaulis maris. Organism_taxid: 394221. Strain: mcs10. Gene: arga/b, mmar10_0365. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, X, Y (436 residues) CATH domains: 3.40.1160.10 3.40.630.30
3s7y
Crystal structure of mmnags in space group p3121 at 4.3 a re
Source: Maricaulis maris. Organism_taxid: 394221. Strain: mcs10. Gene: arga/b, mmar10_0365. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, X (436 residues)
3t7b
Crystal structure of n-acetyl-l-glutamate kinase from yersin
Source: Yersinia pestis. Organism_taxid: 214092. Strain: co92. Gene: argb, y0311, ypo3925, yp_3124. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (255 residues) CATH domain: 3.40.1160.10
Bound ligand:   Het Group GLU is 76.92% similar to enzyme reactant N-acetyl-L-glutamate
3zzf
Crystal structure of the amino acid kinase domain from saccharomyces cerevisiae acetylglutamate kinase complexed with its substrate n-acetylglutamate
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Strain: sigma 1278b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D (291 residues) CATH domain: 3.40.1160.10
3zzg
Crystal structure of the amino acid kinase domain from sacch cerevisiae acetylglutamate kinase without ligands
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Strain: sigma 1278b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D (291 residues) CATH domain: 3.40.1160.10
3zzh
Crystal structure of the amino acid kinase domain from sacch cerevisiae acetylglutamate kinase in complex with its feed-back inhibitor l-arginine
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Strain: sigma 1278b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D (291 residues) CATH domain: 3.40.1160.10
3zzi
Crystal structure of a tetrameric acetylglutamate kinase fro saccharomyces cerevisiae
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Strain: sigma 1278b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D, E, F, G, H (436 residues) CATH domains: 3.40.1160.10 3.40.630.30
4ab7
Crystal structure of a tetrameric acetylglutamate kinase from saccharomyces cerevisiae complexed with its substrate n-acetylglutamate
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Strain: sigma 1278b. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D, E, F, G, H (405 residues) CATH domains: 3.40.1160.10 3.40.630.30
4kzt
Structure mmnags bound with l-arginine
Source: Maricaulis maris. Organism_taxid: 394221. Strain: mcs10. Gene: arga/b, mmar10_0365. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, X, Y (431 residues) CATH domains: 3.40.1160.10 3.40.630.30