_EC 2.7.2.11 Glutamate 5-kinase. 6 PDB entries  
EC 2.-.-.- Transferases. [17,769 PDB entries]
EC 2.7.-.- Transferring phosphorous-containing groups. [10,783 PDB entries]
EC 2.7.2.- Phosphotransferases with a carboxyl group as acceptor. [138 PDB entries]
EC 2.7.2.11 Glutamate 5-kinase. [6 PDB entries]    
2ako

Pathway: Proline Biosynthesis
Reaction: Atp + L-glutamate = adp + L-glutamate 5-phosphate.
 


ATP
+
L-glutamate
=
ADP
+
L-glutamate 5-phosphate
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): Gamma-glutamyl kinase.
Comments: The product rapidly cyclizes to 5-oxoproline and phosphate.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 6 PDB entries in enzyme class E.C.2.7.2.11

  PDB code Protein
2ako
Crystal structure of glutamate 5-kinase from campylobacter jejuni
Source: Campylobacter jejuni. Organism_taxid: 197. Gene: prob. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chains: A, B, C, D (241 residues) CATH domain: 3.40.1160.10
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
2h5g
Crystal structure of human pyrroline-5-carboxylate synthetas
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: aldh18a1. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (417 residues) CATH domains: 3.40.605.10 3.40.309.10
2j5t
Glutamate 5-kinase from escherichia coli complexed with glutamate
Source: Escherichia coli. Organism_taxid: 562. Strain: dh5alpha. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D, E, F, G, H (355 residues) CATH domains: 3.40.1160.10 2.30.130.10
Bound ligand:   Het Group GLU corresponds to enzyme reactant L-glutamate
2j5v
Glutamate 5-kinase from escherichia coli complexed with glutamyl-5-phosphate and pyroglutamic acid
Source: Escherichia coli. Organism_taxid: 562. Strain: dh5alpha. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (323 residues) CATH domains: 3.40.1160.10 2.30.130.10
Bound ligand:   Het Group RGP corresponds to enzyme product L-glutamyl 5-phosphate
2w21
Crystal structure of the aminoacid kinase domain of the glutamate 5 kinase of escherichia coli.
Source: Escherichia coli. Organism_taxid: 511693. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chain: A (246 residues) CATH domain: 3.40.1160.10
4q1t
Crystal structure of a glutamate 5-kinase from burkholderia thailandensis
Source: Burkholderia thailandensis. Organism_taxid: 271848. Strain: e264. Gene: bth_i1143, gamma-glutamyl kinase, prob. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (340 residues) CATH domains: 3.40.1160.10 2.30.130.10