_EC 2.7.11.26 [Tau protein] kinase. 83 PDB entries  
EC 2.-.-.- Transferases. [16,702 PDB entries]
EC 2.7.-.- Transferring phosphorous-containing groups. [10,257 PDB entries]
EC 2.7.11.- Protein-serine/threonine kinases. [2,796 PDB entries]
EC 2.7.11.26 [Tau protein] kinase. [83 PDB entries]    
1cki

Reaction: Atp + [tau protein] = adp + [tau protein] phosphate.
 


ATP
+ [tau protein]
=
ADP
+ [tau protein] phosphate
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): [Tau-protein] kinase. Glycogen synthase kinase-3-beta. Gsk. Protein tau kinase. Tau kinase. Tau-tubulin kinase. Tpk. Ttk.
Comments: Activated by tubulin. Involved in the formation of paired helical filaments, which are the main fibrous component of all fibrillary lesions in brain and are associated with Alzheimer's disease. Formerly Ec 2.7.1.135.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 83 PDB entries in enzyme class E.C.2.7.11.26

  PDB code Protein
1cki
Recombinant casein kinase i delta truncation mutant containing residues 1-317
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Cell_line: 293. Organ: testes. Gene: t7. Expressed in: escherichia coli. Expression_system_taxid: 562. Other_details: t7 RNA polymerase
Chains: A, B (292 residues) CATH domains: 3.30.200.20 1.10.510.10
1ckj
Casein kinase i delta truncation mutant containing residues 1-317 complex with bound tungstate
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Cell_line: 293. Organ: testes. Gene: t7. Expressed in: escherichia coli. Expression_system_taxid: 562. Other_details: host bl21(de3)
Chains: A, B (296 residues) CATH domains: 3.30.200.20 1.10.510.10
1gng
Glycogen synthase kinase-3 beta (gsk3) complex with frattide peptide
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Synthetic: yes. Organism_taxid: 9606
Chains: A, B (350 residues) CATH domains: 3.30.200.20 1.10.510.10
1h8f
Glycogen synthase kinase 3 beta.
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: baculovirus. Expression_system_taxid: 10469.
Chains: A, B (352 residues) CATH domains: 3.30.200.20 1.10.510.10
1i09
Structure of glycogen synthase kinase-3 (gsk3b)
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: unidentified baculovirus. Expression_system_taxid: 10469
Chains: A, B (338 residues) CATH domains: 3.30.200.20 1.10.510.10
1j1b
Binary complex structure of human tau protein kinase i with amppnp
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (354 residues) CATH domains: 3.30.200.20 1.10.510.10
1j1c
Binary complex structure of human tau protein kinase i with adp
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (354 residues) CATH domains: 3.30.200.20 1.10.510.10
1o9u
Glycogen synthase kinase 3 beta complexed with axin peptide
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Synthetic: yes. Other_details: axin peptide
Chain: A (350 residues) CATH domains: 3.30.200.20 1.10.510.10
1phk
Two structures of the catalytic domain of phosphorylase, kinase: an active protein kinase complexed with nucleotide, substrate-analogue and product
Source: Oryctolagus cuniculus. Rabbit. Organism_taxid: 9986. Organ: skeletal. Tissue: skeletal muscle. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (277 residues) CATH domains: 3.30.200.20 1.10.510.10
1pyx
Gsk-3 beta complexed with amp-pnp
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gsk3b. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_cell_line: h5.
Chains: A, B (343 residues) CATH domains: 3.30.200.20 1.10.510.10
1q3d
Gsk-3 beta complexed with staurosporine
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gsk3b. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_cell_line: h5.
Chains: A, B (339 residues) CATH domains: 3.30.200.20 1.10.510.10
1q3w
Gsk-3 beta complexed with alsterpaullone
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gsk3b. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_cell_line: h5.
Chains: A, B (344 residues) CATH domains: 3.30.200.20 1.10.510.10
1q41
Gsk-3 beta complexed with indirubin-3'-monoxime
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gsk3b. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_cell_line: h5.
Chains: A, B (339 residues) CATH domains: 3.30.200.20 1.10.510.10
1q4l
Gsk-3 beta complexed with inhibitor i-5
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gsk3b. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_cell_line: h5.
Chains: A, B (342 residues) CATH domains: 3.30.200.20 1.10.510.10
1q5k
Crystal structure of glycogen synthase kinase 3 in complexed with inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gsk3b. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Expression_system_cell: high five cells.
Chains: A, B (345 residues) CATH domains: 3.30.200.20 1.10.510.10
1ql6
The catalytic mechanism of phosphorylase kinase probed by mutational studies
Source: Oryctolagus cuniculus. Rabbit. Organism_taxid: 9986. Tissue: skeletal muscle. Plasmid: pmw172. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (281 residues) CATH domains: 3.30.200.20 1.10.510.10
1r0e
Glycogen synthase kinase-3 beta in complex with 3-indolyl-4- arylmaleimide inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gsk3b. Expressed in: trichoplusia ni. Expression_system_taxid: 7111.
Chains: A, B (344 residues) CATH domains: 3.30.200.20 1.10.510.10
1uv5
Glycogen synthase kinase 3 beta complexed with 6-bromoindirubin-3'-oxime
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: insect cells.
Chain: A (349 residues) CATH domains: 3.30.200.20 1.10.510.10
1y8g
Catalytic and ubiqutin-associated domains of mark2/par-1: inactive double mutant with selenomethionine
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Gene: mark2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (302 residues) CATH domains: 3.30.200.20 1.10.510.10 1.10.8.10
1zmu
Catalytic and ubiqutin-associated domains of mark2/par-1: wild type
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Gene: mark2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (293 residues) CATH domains: 3.30.200.20 1.10.510.10 1.10.8.10
1zmv
Catalytic and ubiqutin-associated domains of mark2/par-1: k8
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Gene: mark2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (293 residues) CATH domains: 3.30.200.20 1.10.510.10 1.10.8.10
1zmw
Catalytic and ubiqutin-associated domains of mark2/par-1: t208a/s212a inactive double mutant
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Gene: mark2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (302 residues) CATH domains: 3.30.200.20 1.10.510.10 1.10.8.10
2hak
Catalytic and ubiqutin-associated domains of mark1/par-1
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mark1. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D, E, F, G, H (309 residues) CATH domains: 3.30.200.20 1.10.510.10 1.10.8.10
2jld
Extremely tight binding of ruthenium complex to glycogen synthase kinase 3
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes
Chains: A, B (349 residues) CATH domains: 3.30.200.20 1.10.510.10
2o5k
Crystal structure of gsk3beta in complex with a benzoimidazol inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chain: A (350 residues) CATH domains: 3.30.200.20 1.10.510.10
2ow3
Glycogen synthase kinase-3 beta in complex with bis- (indole)maleimide pyridinophane inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gsk3b
Chains: A, B (347 residues) CATH domains: 3.30.200.20 1.10.510.10
2phk
The crystal structure of a phosphorylase kinase peptide subs complex: kinase substrate recognition
Source: Oryctolagus cuniculus. Rabbit. Organism_taxid: 9986. Strain: new zealand white. Cell_line: bl21. Organ: skeletal. Tissue: skeletal muscle. Gene: phkg. Expressed in: escherichia coli bl21(de3).
Chain: A (277 residues) CATH domains: 3.30.200.20 1.10.510.10
2r0i
Crystal structure of a kinase mark2/par-1 mutant
Source: Rattus norvegicus. Organism_taxid: 10116. Gene: mark2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (300 residues) CATH domains: 3.30.200.20 1.10.510.10 1.10.8.10
2v8q
Crystal structure of the regulatory fragment of mammalian ampk in complexes with amp
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606. Expression_system_taxid: 562
Chain: A (102 residues) CATH domain: 3.30.310.80
2v92
Crystal structure of the regulatory fragment of mammalian ampk in complexes with atp-amp
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606. Expression_system_taxid: 562
Chain: A (102 residues) CATH domain: 3.30.310.80
2v9j
Crystal structure of the regulatory fragment of mammalian ampk in complexes with mg.Atp-amp
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606. Expression_system_taxid: 562
Chain: A (102 residues) CATH domain: 3.30.310.80
2wzj
Catalytic and uba domain of kinase mark2/(par-1) k82r, t208e double mutant
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chains: A, B, C, D, E, F (310 residues) CATH domains: 3.30.200.20 1.10.510.10 1.10.8.10
2y8l
Structure of the regulatory fragment of mammalian ampk in co with two adp
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606. Expression_system_taxid: 562
Chain: A (104 residues) CATH domain: 3.30.310.80
Bound ligand:   Het Group ADP corresponds to enzyme product ATP
2y8q
Structure of the regulatory fragment of mammalian ampk in co with one adp
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606. Expression_system_taxid: 562
Chain: A (104 residues) CATH domain: 3.30.310.80
Bound ligand:   Het Group ADP corresponds to enzyme product ATP
2ya3
Structure of the regulatory fragment of mammalian ampk in co with coumarin adp
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606. Expression_system_taxid: 562
Chain: A (102 residues) CATH domain: 3.30.310.80
3du8
Crystal structure of gsk-3 beta in complex with nms-869553a
Source: Homo sapiens. Organism_taxid: 9606. Gene: gsk3b. Expressed in: spodoptera frugiperda. Expression_system_cell_line: sf9.
Chains: A, B (336 residues) CATH domains: 3.30.200.20 1.10.510.10
3f7z
X-ray co-crystal structure of glycogen synthase kinase 3beta complex with an inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gsk3b. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108
Chains: A, B (340 residues) CATH domains: 3.30.200.20 1.10.510.10
3f88
Glycogen synthase kinase 3beta inhibitor complex
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gsk3b. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108.
Chains: A, B (341 residues) CATH domains: 3.30.200.20 1.10.510.10
3gb2
Gsk3beta inhibitor complex
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gsk3b, gsk3beta. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108.
Chain: A (341 residues) CATH domains: 3.30.200.20 1.10.510.10
3i4b
Crystal structure of gsk3b in complex with a pyrimidylpyrrole inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gsk3b. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_cell_line: high-5.
Chains: A, B (359 residues) CATH domains: 3.30.200.20 1.10.510.10
3iec
Helicobacter pylori caga inhibits par1/mark family kinases b mimicking host substrates
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: caga, emk1, mark2. Expressed in: escherichia coli. Expression_system_taxid: 562. Helicobacter pylori. Campylobacter pylori. Organism_taxid: 210.
Chains: A, B, C, D (311 residues) CATH domains: 3.30.200.20 1.10.510.10 1.10.8.10
3l1s
3-aryl-4-(arylhydrazono)-1h-pyrazol-5-ones: highly ligand ef and potent inhibitors of gsk3
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gsk3b. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Expression_system_cell_line: insect cell.
Chains: A, B (336 residues) CATH domains: 3.30.200.20 1.10.510.10
3m1s
Structure of ruthenium half-sandwich complex bound to glycog synthase kinase 3
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gsk3b. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (348 residues) CATH domains: 3.30.200.20 1.10.510.10
3ose
Structure of the kinase associated domain 1 (ka1) from mark1
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: mark1, kiaa1477, mark. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (100 residues) CATH domain: 3.30.310.80
3pup
Structure of glycogen synthase kinase 3 beta (gsk3b) in comp ruthenium octasporine ligand (os1)
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gsk3b. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (346 residues) CATH domains: 3.30.200.20 1.10.510.10
3q3b
6-amino-4-(pyrimidin-4-yl)pyridones: novel glycogen synthase inhibitors
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gsk3b. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7118
Chains: A, B (344 residues)
3say
Crystal structure of human glycogen synthase kinase 3 beta ( complex with inhibitor 142
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gsk3b. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108.
Chains: A, B (348 residues) CATH domains: 3.30.200.20 1.10.510.10
3sd0
Identification of a glycogen synthase kinase-3b inhibitor th attenuates hyperactivity in clock mutant mice
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gsk3b. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108
Chains: A, B (350 residues) CATH domains: 3.30.200.20 1.10.510.10
3uys
Crystal structure of apo human ck1d
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: csnk1d. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108
Chains: A, B, C, D (281 residues) CATH domains: 3.30.200.20 1.10.510.10
3uyt
Crystal structure of ck1d with pf670462 from p1 crystal form
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: csnk1d. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108
Chains: A, B, C, D (287 residues) CATH domains: 3.30.200.20 1.10.510.10
3uzp
Crystal structure of ck1d with pf670462 from p21 crystal for
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: csnk1d. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108
Chains: A, B (292 residues) CATH domains: 3.30.200.20 1.10.510.10
3zdi
Glycogen synthase kinase 3 beta complexed with axin peptide and inhibitor 7d
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Synthetic: yes. Organism_taxid: 9606
Chain: A (349 residues) CATH domains: 3.30.200.20 1.10.510.10
3zrk
Identification of 2-(4-pyridyl)thienopyridinones as gsk-3bet inhibitors
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_cell_line: sf9.
Chains: A, B (347 residues) CATH domains: 3.30.200.20 1.10.510.10
3zrl
Identification of 2-(4-pyridyl)thienopyridinones as gsk-3bet inhibitors
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_cell_line: sf9.
Chains: A, B (348 residues) CATH domains: 3.30.200.20 1.10.510.10
3zrm
Identification of 2-(4-pyridyl)thienopyridinones as gsk- 3beta inhibitors
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_cell_line: sf9.
Chains: A, B (346 residues) CATH domains: 3.30.200.20 1.10.510.10
4acc
Gsk3b in complex with inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: trichoplusia ni. Expression_system_taxid: 7111.
Chains: A, B (351 residues) CATH domains: 3.30.200.20 1.10.510.10
4acd
Gsk3b in complex with inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: trichoplusia ni. Expression_system_taxid: 7111.
Chains: A, B (351 residues) CATH domains: 3.30.200.20 1.10.510.10
4acg
Gsk3b in complex with inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: trichoplusia ni. Expression_system_taxid: 7111.
Chains: A, B (351 residues) CATH domains: 3.30.200.20 1.10.510.10
4ach
Gsk3b in complex with inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: trichoplusia ni. Expression_system_taxid: 7111.
Chains: A, B (351 residues) CATH domains: 3.30.200.20 1.10.510.10
4afj
5-aryl-4-carboxamide-1,3-oxazoles: potent and selective gsk- inhibitors
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108.
Chains: A, B (344 residues) CATH domains: 3.30.200.20 1.10.510.10
4b7t
Glycogen synthase kinase 3 beta complexed with axin peptide leucettine l4
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_cell_line: sf9. Synthetic: yes. Organism_taxid: 9606
Chain: A (350 residues) CATH domains: 3.30.200.20 1.10.510.10
4cfh
Structure of an active form of mammalian ampk
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606. Expression_system_taxid: 562
Chains: A, C (402 residues)
Bound ligand:   Het Group AMP is 85.19% similar to enzyme product ATP
4dit
Crystal structure of gsk3beta in complex with a imidazopyrid inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gsk3b. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (329 residues) CATH domains: 3.30.200.20 1.10.510.10
4eai
Co-crystal structure of an ampk core with amp
Source: Rattus norvegicus, synthetic, rattus norvegicus. Rat. Organism_taxid: 10116, 32630, 10116. Gene: prkaa1, ampk1. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human.
Chain: A (100 residues) CATH domain: 3.30.310.80
Bound ligand:   Het Group AMP is 85.19% similar to enzyme product ATP
4eaj
Co-crystal of ampk core with amp soaked with atp
Source: Rattus norvegicus, synthetic, rattus norvegicus. Rat. Organism_taxid: 10116, 32630, 10116. Gene: prkaa1, ampk1. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human.
Chain: A (100 residues) CATH domain: 0.0.0.0
Bound ligand:   Het Group ATP corresponds to enzyme reactant ATP
4eak
Co-crystal structure of an ampk core with atp
Source: Rattus norvegicus, synthetic, rattus norvegicus. Rat. Organism_taxid: 10116, 32630, 10116. Gene: prkaa1, ampk1. Expressed in: escherichia coli. Expression_system_taxid: 562. Rattus norvegicus. Organism_taxid: 10116.
Chain: A (92 residues) CATH domain: 0.0.0.0
Bound ligand:   Het Group ATP corresponds to enzyme reactant ATP
4eal
Co-crystal of ampk core with atp soaked with amp
Source: Rattus norvegicus, synthetic, rattus norvegicus. Rat. Organism_taxid: 10116, 32630, 10116. Gene: prkaa1, ampk1. Expressed in: escherichia coli. Expression_system_taxid: 562. Rattus norvegicus. Organism_taxid: 10116.
Chain: A (92 residues) CATH domain: 0.0.0.0
Bound ligand:   Het Group AMP is 85.19% similar to enzyme product ATP
4f2l
Structure of a regulatory domain of ampk
Source: Rattus norvegicus. Brown rat,rat,rats. Organism_taxid: 10116. Gene: prkaa1, ampk1. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (61 residues) CATH domain: 0.0.0.0
4hgt
Crystal structure of ck1d with compound 13
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: csnk1d, hckid. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (283 residues) CATH domains: 3.30.200.20 1.10.510.10
4hnf
Crystal structure of ck1d in complex with pf4800567
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: csnk1d, hckid. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (289 residues) CATH domains: 3.30.200.20 1.10.510.10
4iq6
Gsk-3beta with inhibitor 6-chloro-n-cyclohexyl-4-(1h-pyrrolo b]pyridin-3-yl)pyridin-2-amine
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gsk3b. Expressed in: baculovirus. Expression_system_taxid: 7108.
Chains: A, B (324 residues) CATH domains: 3.30.200.20 1.10.510.10
4j1r
Crystal structure of gsk3b in complex with inhibitor 15r
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gsk3b. Expressed in: trichoplusia ni. Expression_system_taxid: 7111.
Chains: A, B, C, D (344 residues) CATH domains: 3.30.200.20 1.10.510.10
4j71
Crystal structure of gsk3b in complex with inhibitor 1r
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gsk3b. Expressed in: trichoplusia ni. Expression_system_taxid: 7111. Expression_system_cell_line: high five.
Chains: A, B (348 residues) CATH domains: 3.30.200.20 1.10.510.10
4jjr
A p21 crystal form of mammalian casein kinase 1 delta
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: csnk1d, hckid. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (284 residues) CATH domains: 3.30.200.20 1.10.510.10
4kb8
Ck1d in complex with 1-{4-[3-(4-fluorophenyl)-1-methyl-1h-py yl]pyridin-2-yl}-n-methylmethanamine ligand
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: csnk1d, hckid. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_cell_line: sf9
Chains: A, B, C, D (265 residues) CATH domains: 3.30.200.20 1.10.510.10
4kba
Ck1d in complex with 9-[3-(4-fluorophenyl)-1-methyl-1h-pyraz 2,3,4,5-tetrahydropyrido[2,3-f][1,4]oxazepine inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: csnk1d, hckid. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_cell_line: sf9
Chains: A, B, C, D (263 residues) CATH domains: 3.30.200.20 1.10.510.10
4kbc
Ck1d in complex with {4-[3-(4-fluorophenyl)-1h-pyrazol-4-yl] yl}methanol inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: csnk1d, hckid. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_cell_line: sf9
Chains: A, B (288 residues) CATH domains: 3.30.200.20 1.10.510.10
4kbk
Ck1d in complex with (3s)-3-{4-[3-(4-fluorophenyl)-1-methyl- pyrazol-4-yl]pyridin-2-yl}morpholine inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: csnk1d, hckid. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108. Expression_system_cell_line: sf9
Chains: A, B, C, D (283 residues) CATH domains: 3.30.200.20 1.10.510.10
4nm0
Crystal structure of peptide inhibitor-free gsk-3/axin compl
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gsk3b. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: axin, axin1.
Chain: A (356 residues)
4nm3
Crystal structure of gsk-3/axin complex bound to phosphoryla terminal auto-inhibitory ps9 peptide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gsk3b. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: axin, axin1.
Chain: A (358 residues)
4nm5
Crystal structure of gsk-3/axin complex bound to phosphoryla receptor lrp6 c-motif
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gsk3b, hcg_1818062. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: axin1, axin.
Chain: A (361 residues)
4nm7
Crystal structure of gsk-3/axin complex bound to phosphoryla receptor lrp6 e-motif
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gsk3b, hcg_1818062. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: axin1, axin.
Chain: A (355 residues)
4nu1
Crystal structure of a transition state mimic of the gsk-3/a complex bound to phosphorylated n-terminal auto-inhibitory peptide
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: gsk3b. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Human. Organism_taxid: 9606.
Chain: A (357 residues)