_EC 2.7.1.82 Ethanolamine kinase. 15 PDB entries  
EC 2.-.-.- Transferases. [17,943 PDB entries]
EC 2.7.-.- Transferring phosphorous-containing groups. [10,910 PDB entries]
EC 2.7.1.- Phosphotransferases with an alcohol group as acceptor. [1,129 PDB entries]
EC 2.7.1.82 Ethanolamine kinase. [15 PDB entries]    
2cko

Reaction: Atp + ethanolamine = adp + O-phosphoethanolamine.
 


ATP
+
ethanolamine
=
ADP
+
O-phosphoethanolamine
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 15 PDB entries in enzyme class E.C.2.7.1.82

  PDB code Protein
2cko
Crystal structure of human choline kinase alpha 2
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (344 residues) CATH domains: 3.10.450.110 3.90.1200.10
2ckp
Crystal structure of human choline kinase alpha-2 in complex with adp
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (316 residues) CATH domains: 3.10.450.110 3.90.1200.10
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
2ckq
Crystal structure of human choline kinase alpha 2 in complex with phosphocholine
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (346 residues) CATH domains: 3.10.450.110 3.90.1200.10
Bound ligand:   Het Group PC is 72.73% similar to enzyme product ethanolamine
2i7q
Crystal structure of human choline kinase a
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: chka, chk, cki. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (344 residues) CATH domains: 3.10.450.110 3.90.1200.10
2ig7
Crystal structure of human choline kinase b
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: chkb, chetk, chkl. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (335 residues) CATH domains: 3.10.450.110 3.90.1200.10
3f2r
Crystal structure of human choline kinase alpha in complex with hemicholinium-3
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: chka, chk, cki. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (348 residues) CATH domains: Unassigned 3.90.1200.10
3feg
Crystal structure of human choline kinase beta in complex wi phosphorylated hemicholinium-3 and adenosine nucleotide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: chkb, chetk, chkl. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (336 residues) CATH domains: Unassigned 3.90.1200.10
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
3g15
Crystal structure of human choline kinase alpha in complex w hemicholinium-3 and adp
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: chka, chk, cki. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (354 residues) CATH domains: Unassigned 3.90.1200.10
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
3lq3
Crystal structure of human choline kinase beta in complex wi phosphorylated hemicholinium-3 and adenosine nucleotide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: chkb, chetk, chkl. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (339 residues) CATH domains: Unassigned 3.90.1200.10
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
3zm9
The mechanism of allosteric coupling in choline kinase a1 revealed by a rationally designed inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: star.
Chains: A, B (354 residues) CATH domains: Unassigned 3.90.1200.10
4br3
Determination of potential scaffolds for human choline kinase alpha 1 by chemical deconvolution studies
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: star.
Chains: A, B (354 residues) CATH domains: Unassigned 3.90.1200.10
Bound ligands:   Het Group A4V is 51.72% similar to enzyme product ADP
  Het Group PO4 is 62.50% similar to enzyme product ethanolamine
4cg8
Human choline kinase a1 in complex with compound 14
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: star.
Chain: A (353 residues) CATH domains: Unassigned 3.90.1200.10
4cg9
Human choline kinase a1 in complex with compound 12
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: star.
Chain: A (353 residues) CATH domains: Unassigned 3.90.1200.10
4cga
Human choline kinase a1 in complex with compound 5
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: star.
Chain: A (354 residues) CATH domains: Unassigned 3.90.1200.10
4da5
Choline kinase alpha acts through a double-displacement kine mechanism involving enzyme isomerisation, as determined thr enzyme and inhibitor kinetics and structural biology
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: chka, chk, cki. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (352 residues) CATH domains: 3.10.450.110 3.90.1200.10