_EC 2.7.1.71 Shikimate kinase. 46 PDB entries  
EC 2.-.-.- Transferases. [17,500 PDB entries]
EC 2.7.-.- Transferring phosphorous-containing groups. [10,654 PDB entries]
EC 2.7.1.- Phosphotransferases with an alcohol group as acceptor. [1,113 PDB entries]
EC 2.7.1.71 Shikimate kinase. [46 PDB entries]    
1dqs

Pathway: Shikimate and Chorismate Biosynthesis
Reaction: Atp + shikimate = adp + shikimate 3-phosphate.
 


ATP
+
shikimate
=
ADP
+
shikimate 3-phosphate
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 46 PDB entries in enzyme class E.C.2.7.1.71

  PDB code Protein
1dqs
Crystal structure of dehydroquinate synthase (dhqs) complexed with carbaphosphonate, NAD+ and zn2+
Source: Emericella nidulans. Organism_taxid: 162425. Strain: r153. Cellular_location: cytoplasm. Gene: part of aroma. Expressed in: escherichia coli. Expression_system_taxid: 562. Culture collection.
Chains: A, B (381 residues) CATH domains: 3.40.50.1970 1.20.1090.10
Bound ligands:   Het Group CRB is 61.00% similar to enzyme reactant Shikimate
  Het Group NAD is 61.00% similar to enzyme product ADP
1e6c
K15m mutant of shikimate kinase from erwinia chrysanthemi
Source: Erwinia chrysanthemi. Organism_taxid: 556. Gene: arol. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (170 residues) CATH domain: 3.40.50.300
Bound ligand:   Het Group MPD is 66.00% similar to enzyme reactant Shikimate
1kag
Crystal structure of the escherichia coli shikimate kinase i (arok)
Source: Escherichia coli. Organism_taxid: 562. Gene: arok. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chains: A, B (158 residues) CATH domain: 3.40.50.300
1l4u
Crystal structure of shikimate kinase from mycobacterium tuberculosis in complex with mgadp and pt(ii) at 1.8 angstrom resolution
Source: Mycobacterium tuberculosis. Organism_taxid: 1773. Gene: arok. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (165 residues) CATH domain: 3.40.50.300
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
1l4y
Crystal structure of shikimate kinase from mycobacterium tuberculosis in complex with mgadp at 2.0 angstrom resolution
Source: Mycobacterium tuberculosis. Organism_taxid: 1773. Gene: arok. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (165 residues) CATH domain: 3.40.50.300
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
1nr5
Crystal structure of 3-dehydroquinate synthase (dhqs) in com zn2+, NAD and carbaphosphonate
Source: Emericella nidulans. Organism_taxid: 162425. Gene: aroma. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (390 residues) CATH domains: 3.40.50.1970 1.20.1090.10
Bound ligands:   Het Group CRB is 61.11% similar to enzyme reactant Shikimate
  Het Group NAD is 61.36% similar to enzyme product ADP
1nrx
Crystal structure of 3-dehydroquinate synthase (dhqs) in complex with zn2+ and NAD
Source: Emericella nidulans. Organism_taxid: 162425. Gene: aroma. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (380 residues) CATH domains: 3.40.50.1970 1.20.1090.10
Bound ligand:   Het Group NAD is 61.00% similar to enzyme product ADP
1nua
Crystal structure of 3-dehydroquinate synthase (dhqs) in complex with zn2+
Source: Emericella nidulans. Organism_taxid: 162425. Gene: aroma. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (382 residues) CATH domains: 3.40.50.1970 1.20.1090.10
1nva
Crystal structure of 3-dehydroquinate synthase (dhqs) in complex with zn2+ and adp
Source: Emericella nidulans. Organism_taxid: 162425. Gene: aroma. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (380 residues) CATH domains: 3.40.50.1970 1.20.1090.10
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
1nvb
Crystal structure of 3-dehydroquinate synthase (dhqs) in complex with zn2+ and carbaphosphonate
Source: Emericella nidulans. Organism_taxid: 162425. Gene: aroma. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (390 residues) CATH domains: 3.40.50.1970 1.20.1090.10
Bound ligands:   Het Group CRB is 61.00% similar to enzyme reactant Shikimate
  Het Group NAD is 61.00% similar to enzyme product ADP
1nvd
Crystal structure of 3-dehydroquinate synthase (dhqs) in complex with zn2+ and carbaphosphonate
Source: Emericella nidulans. Organism_taxid: 162425. Gene: aroma. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (385 residues) CATH domains: 3.40.50.1970 1.20.1090.10
Bound ligand:   Het Group CRB is 61.00% similar to enzyme reactant Shikimate
1nve
Crystal structure of 3-dehydroquinate synthase (dhqs) in complex with zn2+ and NAD
Source: Emericella nidulans. Organism_taxid: 162425. Gene: aroma. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (378 residues) CATH domains: 3.40.50.1970 1.20.1090.10
Bound ligand:   Het Group NAD is 61.00% similar to enzyme product ADP
1nvf
Crystal structure of 3-dehydroquinate synthase (dhqs) in complex with zn2+, adp and carbaphosphonate
Source: Emericella nidulans. Organism_taxid: 162425. Gene: aroma. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C (388 residues) CATH domains: 3.40.50.1970 1.20.1090.10
Bound ligands:   Het Group CRB is 61.00% similar to enzyme reactant Shikimate
  Het Group ADP corresponds to enzyme product ADP
1sg6
Crystal structure of aspergillus nidulans 3-dehydroquinate s (andhqs) in complex with zn2+ and NAD+, at 1.7d
Source: Emericella nidulans. Organism_taxid: 162425. Gene: aroma, arom. Expressed in: escherichia coli. Expression_system_taxid: 562. Collection.
Chains: A, B (377 residues) CATH domains: 3.40.50.1970 1.20.1090.10
Bound ligand:   Het Group NAD is 61.36% similar to enzyme product ADP
1shk
The three-dimensional structure of shikimate kinase from erw chrysanthemi
Source: Erwinia chrysanthemi. Organism_taxid: 556. Strain: ncppb 1066. Cellular_location: cytoplasm. Gene: arol. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_variant: (de3) plyss.
Chains: A, B (158 residues) CATH domain: 3.40.50.300
1u8a
Crystal structure of mycobacterium tuberculosis shikimate kinase in complex with shikimate and adp at 2.15 angstrom resolution
Source: Mycobacterium tuberculosis. Organism_taxid: 1773. Gene: arok. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (163 residues) CATH domain: 3.40.50.300
Bound ligands:   Het Group SKM corresponds to enzyme reactant Shikimate
  Het Group ADP corresponds to enzyme product ADP
1via
Crystal structure of shikimate kinase
Source: Campylobacter jejuni. Organism_taxid: 197. Gene: arok. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (161 residues) CATH domain: 3.40.50.300
1we2
Crystal structure of shikimate kinase from mycobacterium tuberculosis in complex with mgadp and shikimic acid
Source: Mycobacterium tuberculosis. Organism_taxid: 1773. Gene: arok. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (165 residues) CATH domain: 3.40.50.300
Bound ligands:   Het Group DHK corresponds to enzyme reactant Shikimate
  Het Group ADP corresponds to enzyme product ADP
1zuh
Structural basis for shikimate-binding specificity of helico pylori shikimate kinase
Source: Helicobacter pylori. Organism_taxid: 85962. Strain: 26695. Gene: arok. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (151 residues) CATH domain: 3.40.50.300
1zui
Structural basis for shikimate-binding specificity of helico pylori shikimate kinase
Source: Helicobacter pylori. Organism_taxid: 85962. Strain: 26695. Gene: arok. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (158 residues) CATH domain: 3.40.50.300
Bound ligand:   Het Group SKM corresponds to enzyme reactant Shikimate
1zyu
Crystal structure of mycobacterium tuberculosis shikimate kinase in complex with shikimate and amppcp at 2.85 angstrom resolution
Source: Mycobacterium tuberculosis. Organism_taxid: 1773. Gene: arok. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (168 residues) CATH domain: 3.40.50.300
Bound ligands:   Het Group SKM corresponds to enzyme reactant Shikimate
  Het Group ACP is 81.00% similar to enzyme product ADP
2dfn
Structure of shikimate kinase from mycobacterium tuberculosis complexed with adp and shikimate at 1.9 angstrons of resolution
Source: Mycobacterium tuberculosis. Organism_taxid: 1773. Gene: arok. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (165 residues) CATH domain: 3.40.50.300
Bound ligands:   Het Group SKM corresponds to enzyme reactant Shikimate
  Het Group ADP corresponds to enzyme product ADP
2dft
Structure of shikimate kinase from mycobacterium tuberculosis complexed with adp and mg at 2.8 angstrons of resolution
Source: Mycobacterium tuberculosis. Organism_taxid: 1773. Gene: arok. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D (156 residues) CATH domain: 3.40.50.300
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
2g1j
Crystal structure of mycobacterium tuberculosis shikimate kinase at 2.0 angstrom resolution
Source: Mycobacterium tuberculosis. Organism_taxid: 1773. Gene: arok. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (159 residues) CATH domain: 3.40.50.300
2g1k
Crystal structure of mycobacterium tuberculosis shikimate kinase in complex with shikimate at 1.75 angstrom resolution
Source: Mycobacterium tuberculosis. Organism_taxid: 1773. Gene: arok. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (168 residues) CATH domain: 3.40.50.300
Bound ligand:   Het Group SKM corresponds to enzyme reactant Shikimate
2iyq
Shikimate kinase from mycobacterium tuberculosis in complex with shikimate and adp
Source: Mycobacterium tuberculosis. Organism_taxid: 83332. Strain: h37rv. Atcc: 25618. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (166 residues) CATH domain: 3.40.50.300
Bound ligands:   Het Group SKM corresponds to enzyme reactant Shikimate
  Het Group ADP corresponds to enzyme product ADP
2iyr
Shikimate kinase from mycobacterium tuberculosis in complex with shikimate
Source: Mycobacterium tuberculosis. Organism_taxid: 83332. Strain: h37rv. Atcc: 25618. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (164 residues) CATH domain: 3.40.50.300
Bound ligand:   Het Group SKM corresponds to enzyme reactant Shikimate
2iys
Shikimate kinase from mycobacterium tuberculosis in complex with shikimate, open lid (conf. A)
Source: Mycobacterium tuberculosis. Organism_taxid: 83332. Strain: h37rv. Atcc: 25618. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (175 residues) CATH domain: 3.40.50.300
Bound ligand:   Het Group SKM corresponds to enzyme reactant Shikimate
2iyt
Shikimate kinase from mycobacterium tuberculosis in unliganded state, open lid (conf. A)
Source: Mycobacterium tuberculosis. Organism_taxid: 83332. Strain: h37rv. Atcc: 25618. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (175 residues) CATH domain: 3.40.50.300
2iyu
Shikimate kinase from mycobacterium tuberculosis in complex with adp, open lid (conf. A)
Source: Mycobacterium tuberculosis. Organism_taxid: 83332. Strain: h37rv. Atcc: 25618. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (167 residues) CATH domain: 3.40.50.300
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
2iyv
Shikimate kinase from mycobacterium tuberculosis in complex with adp, open lid (conf. B)
Source: Mycobacterium tuberculosis. Organism_taxid: 83332. Strain: h37rv. Atcc: 25618. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (179 residues) CATH domain: 3.40.50.300
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
2iyw
Shikimate kinase from mycobacterium tuberculosis in complex with mgatp, open lid (conf. B)
Source: Mycobacterium tuberculosis. Organism_taxid: 83332. Strain: h37rv. Atcc: 25618. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (178 residues) CATH domain: 3.40.50.300
Bound ligand:   Het Group ATP corresponds to enzyme reactant ATP
2iyx
Shikimate kinase from mycobacterium tuberculosis in complex with shikimate and so4
Source: Mycobacterium tuberculosis. Organism_taxid: 83332. Strain: h37rv. Atcc: 25618. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (169 residues) CATH domain: 3.40.50.300
Bound ligand:   Het Group SKM corresponds to enzyme reactant Shikimate
2iyy
Shikimate kinase from mycobacterium tuberculosis in complex with shikimate-3-phosphate and so4
Source: Mycobacterium tuberculosis. Organism_taxid: 83332. Strain: h37rv. Atcc: 25618. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (169 residues) CATH domain: 3.40.50.300
Bound ligand:   Het Group S3P corresponds to enzyme product shikimate 3-phosphate
2iyz
Shikimate kinase from mycobacterium tuberculosis in complex with shikimate-3-phosphate and adp
Source: Mycobacterium tuberculosis. Organism_taxid: 83332. Strain: h37rv. Atcc: 25618. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (168 residues) CATH domain: 3.40.50.300
Bound ligands:   Het Group ADP corresponds to enzyme product ADP
  Het Group S3P corresponds to enzyme product shikimate 3-phosphate
2pt5
Crystal structure of shikimate kinase (aq_2177) from aquifex vf5
Source: Aquifex aeolicus. Organism_taxid: 224324. Strain: vf5. Gene: arok. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (166 residues) CATH domain: 3.40.50.300
2shk
The three-dimensional structure of shikimate kinase from erwinia chrysanthemi complexed with adp
Source: Erwinia chrysanthemi. Organism_taxid: 556. Strain: ncppb 1066. Cellular_location: cytoplasm. Gene: arol. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_variant: (de3) plyss.
Chains: A, B (158 residues) CATH domain: 3.40.50.300
Bound ligand:   Het Group ADP corresponds to enzyme product ADP
3baf
Crystal structure of shikimate kinase from mycobacterium tuberculosis in complex with amp-pnp
Source: Mycobacterium tuberculosis. Organism_taxid: 1773. Gene: arok. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (165 residues) CATH domain: 3.40.50.300
Bound ligands:   Het Group SKM corresponds to enzyme reactant Shikimate
  Het Group ANP is 81.00% similar to enzyme product ADP
3hr7
Crystal structure of the shikimate kinase-sulfate complex fr helicobacter pylori
Source: Helicobacter pylori. Organism_taxid: 85962. Strain: 26695. Gene: arok. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (151 residues) CATH domain: 3.40.50.300
3mrs
Crystal structure of shikimate kinase mutant (r57a) from hel pylori
Source: Helicobacter pylori. Organism_taxid: 85962. Strain: 26695. Gene: arok. Expressed in: escherichia coli. Expression_system_taxid: 85962.
Chain: A (149 residues) CATH domain: 3.40.50.300
3muf
Shikimate kinase from helicobacter pylori in complex with sh phosphate and adp
Source: Helicobacter pylori. Organism_taxid: 210. Strain: 26695. Gene: arok. Expressed in: escherichia coli. Expression_system_taxid: 85962.
Chain: A (160 residues) CATH domain: 3.40.50.300
Bound ligands:   Het Group ADP corresponds to enzyme product ADP
  Het Group S3P corresponds to enzyme product shikimate
3n2e
Crystal structure of helicobactor pylori shikimate kinase in with nsc162535
Source: Helicobacter pylori. Organism_taxid: 85962. Strain: 26695. Gene: arok. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C (168 residues) CATH domain: 3.40.50.300
Bound ligand:   Het Group TLA is 46.67% similar to enzyme reactant Shikimate
3nwj
Crystal structure of shikimate kinase from arabidopsis thali (atsk2)
Source: Arabidopsis thaliana. Mouse-ear cress,thale-cress. Organism_taxid: 3702. Strain: col-0. Gene: at4g39540, at4g39540/f23k16_170. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (194 residues) CATH domain: 3.40.50.300
3trf
Structure of a shikimate kinase (arok) from coxiella burneti
Source: Coxiella burnetii. Organism_taxid: 777. Strain: rsa493. Gene: arok, cbu_1892. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (170 residues) CATH domain: 3.40.50.300
3vaa
1.7 angstrom resolution crystal structure of shikimate kinas bacteroides thetaiotaomicron
Source: Bacteroides thetaiotaomicron. Organism_taxid: 818. Strain: vpi-5482. Gene: arok, bt_3393. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chains: A, B, C (176 residues) CATH domain: 3.40.50.300
Bound ligand:   Het Group GOL is 50.00% similar to enzyme reactant Shikimate
4bqs
Crystal structure of mycobacterium tuberculosis shikimate kinase in complex with adp and a shikimic acid derivative.
Source: Mycobacterium tuberculosis. Organism_taxid: 1773. Atcc: 27294. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C (169 residues) CATH domain: 3.40.50.300
Bound ligands:   Het Group K2Q is 80.00% similar to enzyme reactant Shikimate
  Het Group ADP corresponds to enzyme product ADP