_EC 2.5.1.1 Dimethylallyltranstransferase. 85 PDB entries  
EC 2.-.-.- Transferases. [17,949 PDB entries]
EC 2.5.-.- Transferring alkyl or aryl groups, other than methyl groups. [1,301 PDB entries]
EC 2.5.1.- Transferring alkyl or aryl groups, other than methyl groups. [1,301 PDB entries]
EC 2.5.1.1 Dimethylallyltranstransferase. [85 PDB entries]    
1fps

Pathway: Terpenoid biosynthesis
Reaction: Dimethylallyl diphosphate + isopentenyl diphosphate = diphosphate + geranyl diphosphate.
 


Dimethylallyl diphosphate
+
isopentenyl diphosphate
=
diphosphate
+
geranyl diphosphate
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): Dimethylallyltransferase. Geranyl-diphosphate synthase. Prenyltransferase.
Comments: Will not accept larger prenyl diphosphates as efficient donors.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 85 PDB entries in enzyme class E.C.2.5.1.1

  PDB code Protein
1fps
Crystal structure of recombinant farnesyl diphosphate syntha angstroms resolution
Source: Gallus gallus. Chicken. Organism_taxid: 9031
Chain: A (348 residues) CATH domain: 1.10.600.10
1ubv
Structure of farnesyl pyrophosphate synthetase
Source: Gallus gallus. Chicken. Organism_taxid: 9031. Organ: liver. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (348 residues) CATH domain: 1.10.600.10
1ubw
Structure of farnesyl pyrophosphate synthetase
Source: Gallus gallus. Chicken. Organism_taxid: 9031. Organ: liver. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (348 residues) CATH domain: 1.10.600.10
Bound ligand:   Het Group GPP corresponds to enzyme product geranyl
1ubx
Structure of farnesyl pyrophosphate synthetase
Source: Gallus gallus. Chicken. Organism_taxid: 9031. Organ: liver. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (348 residues) CATH domain: 1.10.600.10
Bound ligand:   Het Group FPP is 79.17% similar to enzyme product geranyl
1uby
Structure of farnesyl pyrophosphate synthetase
Source: Gallus gallus. Chicken. Organism_taxid: 9031. Organ: liver. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (348 residues) CATH domain: 1.10.600.10
Bound ligand:   Het Group DMA corresponds to enzyme reactant Dimethylallyl
1yq7
Human farnesyl diphosphate synthase complexed with risedrona
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fdps. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (334 residues) CATH domain: 1.10.600.10
Bound ligand:   Het Group PO4 is 55.56% similar to enzyme product diphosphate
1yv5
Human farnesyl diphosphate synthase complexed with mg and ri
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fdps. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (336 residues) CATH domain: 1.10.600.10
Bound ligand:   Het Group PO4 is 55.56% similar to enzyme product diphosphate
1zw5
X-ray structure of farnesyl diphosphate synthase protein
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fdps. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (339 residues) CATH domain: 1.10.600.10
Bound ligand:   Het Group IPE corresponds to enzyme reactant Dimethylallyl
2dh4
Geranylgeranyl pyrophosphate synthase
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: ggpps. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (326 residues) CATH domain: 1.10.600.10
2e8t
S. Cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium, fspp and ipp
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (299 residues) CATH domain: 1.10.600.10
Bound ligand:   Het Group IPE corresponds to enzyme reactant Dimethylallyl diphosphate
2e8u
S. Cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and ipp (p21)
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (288 residues) CATH domain: 1.10.600.10
Bound ligand:   Het Group IPE corresponds to enzyme reactant Dimethylallyl diphosphate
2e8v
S. Cerevisiae geranylgeranyl pyrophosphate synthase in complex with product ggpp (p21)
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (292 residues) CATH domain: 1.10.600.10
Bound ligand:   Het Group GRG is 65.00% similar to enzyme product geranyl diphosphate
2e8w
S. Cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and ipp
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (316 residues) CATH domain: 1.10.600.10
Bound ligand:   Het Group IPE corresponds to enzyme reactant Dimethylallyl diphosphate
2e8x
S. Cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and gpp
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (297 residues) CATH domain: 1.10.600.10
Bound ligand:   Het Group GPP corresponds to enzyme product geranyl diphosphate
2e90
S. Cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium, pyrophosphate and fpp
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (299 residues) CATH domain: 1.10.600.10
Bound ligands:   Het Group PPV corresponds to enzyme product diphosphate
  Het Group FPP is 79.00% similar to enzyme product geranyl diphosphate
2e91
S. Cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and bph-91
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (296 residues) CATH domain: 1.10.600.10
2e92
S. Cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and bph-261
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (291 residues) CATH domain: 1.10.600.10
2e93
S. Cerevisiae geranylgeranyl pyrophosphate synthase in complex with bph-629
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (299 residues) CATH domain: 1.10.600.10
2e94
S. Cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and bph-364
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (303 residues) CATH domain: 1.10.600.10
2e95
S. Cerevisiae geranylgeranyl pyrophosphate synthase in complex with magnesium and bph-675
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (316 residues) CATH domain: 1.10.600.10
2f7m
Crystal structure of unliganded human fpps
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fdps, fps, kiaa1293. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: F (341 residues) CATH domain: 1.10.600.10
Bound ligand:   Het Group PO4 is 55.56% similar to enzyme product diphosphate
2f89
Crystal structure of human fpps in complex with pamidronate
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fdps, fps, kiaa1293. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: F (346 residues) CATH domain: 1.10.600.10
Bound ligand:   Het Group PO4 is 55.56% similar to enzyme product diphosphate
2f8c
Crystal structure of fpps in complex with zoledronate
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fdps, fps, kiaa1293. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: F (343 residues) CATH domain: 1.10.600.10
Bound ligand:   Het Group PO4 is 55.56% similar to enzyme product diphosphate
2f8z
Crystal structure of human fpps in complex with zoledronate isopentenyl diphosphate
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fdps, fps, kiaa1293. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: F (346 residues) CATH domain: 1.10.600.10
Bound ligand:   Het Group IPE corresponds to enzyme reactant Dimethylallyl
2f92
Crystal structure of human fpps in complex with alendronate
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fdps, fps, kiaa1293. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: F (343 residues) CATH domain: 1.10.600.10
Bound ligand:   Het Group PO4 is 55.56% similar to enzyme product diphosphate
2f94
Crystal structure of human fpps in complex with ibandronate
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fdps, fps, kiaa1293. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: F (342 residues) CATH domain: 1.10.600.10
Bound ligand:   Het Group PO4 is 55.56% similar to enzyme product diphosphate
2f9k
Crystal structure of human fpps in complex with zoledronate
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fdps, fps, kiaa1293. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: F (343 residues) CATH domain: 1.10.600.10
Bound ligand:   Het Group PO4 is 55.56% similar to enzyme product diphosphate
2ftz
Crystal structure of geranyltranstransferase (ec 2.5.1.10) ( from thermotoga maritima at 1.90 a resolution
Source: Thermotoga maritima. Organism_taxid: 243274. Strain: msb8. Gene: tm0161. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (265 residues) CATH domain: 1.10.600.10
2j1o
Geranylgeranyl diphosphate synthase from sinapis alba
Source: Sinapis alba. White mustard. Organism_taxid: 3728. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chain: A (255 residues) CATH domain: 1.10.600.10
2j1p
Geranylgeranyl diphosphate synthase from sinapis alba in complex with ggpp
Source: Sinapis alba. White mustard. Organism_taxid: 3728. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chains: A, B (276 residues) CATH domain: 1.10.600.10
Bound ligand:   Het Group GRG is 65.52% similar to enzyme product geranyl
2opm
Human farnesyl diphosphate synthase complexed with bisphosph 461
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fdps, fps, kiaa1293. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (336 residues) CATH domain: 1.10.600.10
Bound ligand:   Het Group PO4 is 55.56% similar to enzyme product diphosphate
2opn
Human farnesyl diphosphate synthase complexed with bisphosph 527
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fdps, fps, kiaa1293. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (336 residues) CATH domain: 1.10.600.10
Bound ligand:   Het Group PO4 is 55.56% similar to enzyme product diphosphate
2q80
Crystal structure of human geranylgeranyl pyrophosphate synt to ggpp
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ggps1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B, C, D, E, F (285 residues) CATH domain: 1.10.600.10
Bound ligand:   Het Group GRG is 65.52% similar to enzyme product geranyl
2qis
Crystal structure of human farnesyl pyrophosphate synthase t mutant bound to risedronate
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fdps, fps, kiaa1293. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (340 residues) CATH domain: 1.10.600.10
2rah
Human fdps synthase in complex with novel inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fdps, fps, kiaa1293. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (340 residues) CATH domain: 1.10.600.10
2vf6
Human fdps synthase in complex with minodronate
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (337 residues) CATH domain: 1.10.600.10
2z4v
S. Cerevisiae geranylgeranyl pyrophosphate synthase in compl magnesium and ggpp (inhibitory site)
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (314 residues) CATH domain: 1.10.600.10
Bound ligand:   Het Group GRG is 65.00% similar to enzyme product geranyl diphosphate
2z4w
S. Cerevisiae geranylgeranyl pyrophosphate synthase in compl magnesium and bph-749
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (292 residues) CATH domain: 1.10.600.10
2z4x
S. Cerevisiae geranylgeranyl pyrophosphate synthase in compl magnesium and bph-252 (p21)
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (286 residues) CATH domain: 1.10.600.10
2z4y
S. Cerevisiae geranylgeranyl pyrophosphate synthase in compl magnesium and bph-252
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (291 residues) CATH domain: 1.10.600.10
2z4z
S. Cerevisiae geranylgeranyl pyrophosphate synthase in compl magnesium and bph-sc01
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (315 residues) CATH domain: 1.10.600.10
2z50
S. Cerevisiae geranylgeranyl pyrophosphate synthase in compl bph-28
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (282 residues) CATH domain: 1.10.600.10
2z52
S. Cerevisiae geranylgeranyl pyrophosphate synthase in compl magnesium and bph-23
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (296 residues) CATH domain: 1.10.600.10
2z78
S. Cerevisiae geranylgeranyl pyrophosphate synthase in compl bph-806
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (321 residues) CATH domain: 1.10.600.10
2z7h
S. Cerevisiae geranylgeranyl pyrophosphate synthase in complex with inhibitor bph-210
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (308 residues) CATH domain: 1.10.600.10
2z7i
S. Cerevisiae geranylgeranyl pyrophosphate synthase in compl inhibitor bph-742
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (313 residues) CATH domain: 1.10.600.10
2zeu
S. Cerevisiae geranylgeranyl pyrophosphate synthase in compl bph-715
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (305 residues) CATH domain: 1.10.600.10
2zev
S. Cerevisiae geranylgeranyl pyrophosphate synthase in compl magnesium, ipp and bph-715
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (298 residues) CATH domain: 1.10.600.10
Bound ligand:   Het Group IPE corresponds to enzyme reactant Dimethylallyl
3b7l
Human farnesyl diphosphate synthase complexed with mg and mi
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fdps, fps, kiaa1293. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (343 residues) CATH domain: 1.10.600.10
3cp6
Crystal structure of human farnesyl diphosphate synthase (t2 mutant) complexed with mg and biphosphonate inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fdps, fps, kiaa1293. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (334 residues) CATH domain: 1.10.600.10
3lk5
Crystal structure of putative geranylgeranyl pyrophosphate s from corynebacterium glutamicum
Source: Corynebacterium glutamicum. Organism_taxid: 1718. Strain: atcc 13032. Gene: cgl2172. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (333 residues) CATH domain: 1.10.600.10
3n1v
Human fpps complex with fbs_01
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fdps, fps, kiaa1293. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: F (343 residues) CATH domain: 1.10.600.10
Bound ligand:   Het Group PO4 is 55.00% similar to enzyme product diphosphate
3n1w
Human fpps complex with fbs_02
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fdps, fps, kiaa1293. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: F (343 residues) CATH domain: 1.10.600.10
Bound ligands:   Het Group PO4 is 55.00% similar to enzyme product diphosphate
  Het Group 3N2 is 43.00% similar to enzyme product geranyl diphosphate
3n3l
Human fpps complex with fbs_03
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fdps, fps, kiaa1293. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: F (343 residues) CATH domain: 1.10.600.10
Bound ligands:   Het Group PO4 is 55.00% similar to enzyme product diphosphate
  Het Group MS0 is 41.00% similar to enzyme product geranyl diphosphate
3n45
Human fpps complex with fbs_04 and zoledronic acid/mg2+
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fdps, fps, kiaa1293. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: F (343 residues) CATH domain: 1.10.600.10
Bound ligand:   Het Group PO4 is 55.00% similar to enzyme product diphosphate
3n46
Human fpps complex with nov_980 and zoledronic acid/mg2+
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fdps, fps, kiaa1293. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: F (343 residues) CATH domain: 1.10.600.10
Bound ligand:   Het Group PO4 is 55.00% similar to enzyme product diphosphate
3n49
Human fpps complex with nov_292
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fdps, fps, kiaa1293. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: F (343 residues) CATH domain: 1.10.600.10
Bound ligand:   Het Group PO4 is 55.00% similar to enzyme product diphosphate
3n5h
Human fpps complex with nov_304
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fdps, fps, kiaa1293. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: F (343 residues) CATH domain: 1.10.600.10
Bound ligand:   Het Group PO4 is 55.00% similar to enzyme product diphosphate
3n5j
Human fpps complex with nov_311
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fdps, fps, kiaa1293. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: F (343 residues) CATH domain: 1.10.600.10
Bound ligand:   Het Group PO4 is 55.00% similar to enzyme product diphosphate
3n6k
Human fpps complex with nov_823
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fdps, fps, kiaa1293. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: F (341 residues) CATH domain: 1.10.600.10
Bound ligand:   Het Group PO4 is 55.00% similar to enzyme product diphosphate
3qkc
Crystal structure of geranyl diphosphate synthase small subu antirrhinum majus
Source: Antirrhinum majus. Garden snapdragon,snapdragon. Organism_taxid: 4151. Gene: aas82859. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: B, A (256 residues) CATH domain: 1.10.600.10
3qqv
Crystal structure of geranylgeranyl pyrophosphate synthase f corynebacterium glutamicum complexed with isoprenyl diphosp magnesium
Source: Corynebacterium glutamicum. Organism_taxid: 1718. Strain: atcc 13032. Gene: cgl2172. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (357 residues) CATH domain: 1.10.600.10
Bound ligand:   Het Group DMA corresponds to enzyme reactant Dimethylallyl
3rye
Human fdps synthase in complex with a n-methyl pyridinum bisphosphonate
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fdps, fps, kiaa1293. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (341 residues) CATH domain: 1.10.600.10
3s4j
Human fdps synthase in complex with a rigid analog of risedr
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fdps, fps, kiaa1293. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (340 residues) CATH domain: 1.10.600.10
4dem
Crystal structure of human fpps in complex with ys_04_70
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fdps, fps, kiaa1293. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: F (346 residues) CATH domain: 1.10.600.10
4ga3
Crystal structure of human farnesyl diphosphate synthase in with bph-1260
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fdps, fps, kiaa1293. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (346 residues) CATH domain: 1.10.600.10
4h5c
Crystal structure of human fpps in ternary complex with ys04 inorganic phosphate
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fdps, fps, kiaa1293. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: F (346 residues) CATH domain: 1.10.600.10
4h5d
Crystal structure of human fpps in ternary complex with ys04 inorganic pyrophosphate
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fdps, fps, kiaa1293. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: F (346 residues) CATH domain: 1.10.600.10
4h5e
Crystal structure of human fpps in ternary complex with ys04 isopentenyl pyrophosphate
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fdps, fps, kiaa1293. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: F (346 residues) CATH domain: 1.10.600.10
4jvj
Crystal structure of human fpps in complex with magnesium, c and sulfate
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fdps, fps, kiaa1293. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: F (343 residues) CATH domain: 1.10.600.10
4jzb
Crystal structure of leshmaniasis major farnesyl diphosphate in complex with 1-(2-hydroxy-2,2-diphosphonoethyl)-3- phenylpyridinium, ipp and ca2+
Source: Leishmania major. Organism_taxid: 5664. Gene: fpps, lmjf_22_1360. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (362 residues) CATH domain: 1.10.600.10
Bound ligand:   Het Group IPE corresponds to enzyme reactant Dimethylallyl
4kfa
Crystal structure of human farnesyl pyrophosphate synthase ( mutant) complexed with mg and zoledronate
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fdps, fps, kiaa1293. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (338 residues) CATH domain: 1.10.600.10
4kk2
Crystal structure of a chimeric fpp/gfpp synthase (target ef from artemisia spiciformis (1-72:gi751454468,73-346:gi75233 structure
Source: Artemisia spiciformis. Spiked big sagebrush. Organism_taxid: 235357. Gene: fds-5, fds-1. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (338 residues) CATH domain: 1.10.600.10
4kpd
Crystal structure of human farnesyl pyrophosphate synthase ( mutant complexed with mg, risedronate and isopentenyl pyrop
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fdps, fps, kiaa1293. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (341 residues) CATH domain: 1.10.600.10
4kpj
Crystal structure of farnesyl pyrophosphate synthase (y204a) complexed with mg, pamidronate
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fdps, fps, kiaa1293. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (338 residues) CATH domain: 1.10.600.10
4kq5
Crystal structure of human farnesyl pyrophosphate synthase m (y204a) complexed with mg and zoledronate
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fdps, fps, kiaa1293. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (342 residues) CATH domain: 1.10.600.10
4kqs
Crystal structure of farnesyl pyrophosphate synthase mutant complexed with mg, risedronate and isopentenyl pyrophosphat
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fdps, fps, kiaa1293. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (340 residues) CATH domain: 1.10.600.10
4kqu
Crystal structure of farnesyl synthase mutant (y204a) comple mg, alendronate and isopentenyl pyrophosphate
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fdps, fps, kiaa1293. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (340 residues) CATH domain: 1.10.600.10
4l2x
Crystal structure of human fpps in complex with magnesium, c and inorganic pyrophosphate
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fdps, fps, kiaa1293. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: F (346 residues) CATH domain: 1.10.600.10
Bound ligand:   Het Group POP corresponds to enzyme product diphosphate
4lfv
Crystal structure of human fpps in complex with ys0470 and t molecules of inorganic phosphate
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fdps, fps, kiaa1293. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: F (342 residues) CATH domain: 1.10.600.10
Bound ligand:   Het Group PO4 is 55.56% similar to enzyme product diphosphate
4lpg
Crystal structure of human fpps in complex with cl01131
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fdps, fps, kiaa1293. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: F (341 residues) CATH domain: 1.10.600.10
4lph
Crystal structure of human fpps in complex with cl03093
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fdps, fps, kiaa1293. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: F (342 residues) CATH domain: 1.10.600.10
4p0v
Crystal structure of human farnesyl diphosphoate synthase in with zoledronate and taxodione
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fdps, fps, kiaa1293. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (346 residues) CATH domain: 1.10.600.10
4p0w
Human farnesyl diphosphate synthase in complex with arenaron zoledronate
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fdps, fps, kiaa1293. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (346 residues) CATH domain: 1.10.600.10
4p0x
Human farnesyl diphosphate synthase in complex with taxodion
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fdps, fps, kiaa1293. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (330 residues) CATH domain: 1.10.600.10