_EC 2.4.2.43 Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase. 0 PDB entries  
EC 2.-.-.- Transferases. [17,943 PDB entries]
EC 2.4.-.- Glycosyltransferases. [1,918 PDB entries]
EC 2.4.2.- Pentosyltransferases. [897 PDB entries]
EC 2.4.2.43 Lipid IV(A) 4-amino-4-deoxy-L-arabinosyltransferase. [-]    

Reaction: 4-amino-4-deoxy-alpha-L-arabinopyranosyl di-trans,octa-cis-undecaprenyl phosphate + lipid IV(A) = lipid II(A) + di-trans,octa-cis-undecaprenyl phosphate.
 

4-amino-4-deoxy-alpha-L-arabinopyranosyl di-trans,octa-cis-undecaprenyl phosphate
+ lipid IV(A)
= lipid II(A)
+
di-trans,octa-cis-undecaprenyl phosphate
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): 4-amino-4-deoxy-L-arabinose lipid A transferase. Lipid A 4-amino-4-deoxy-L-arabinosyltransferase. Polymyxin resistance protein PmrK. Undecaprenyl phosphate-alpha-4-amino-4-deoxy-L-arabinose arabinosyl transferase. Undecaprenyl phosphate-alpha-L-Ara4N transferase.
Comments: Integral membrane protein present in the inner membrane of certain Gram negative endobacteria. In strains that do not produce 3-deoxy-D-manno-octulosonic acid (Kdo), the enzyme adds a single arabinose unit to the 1-phosphate moiety of the tetra-acylated lipid A precursor, lipid IV(A). In the presence of a Kdo disaccharide, the enzyme primarily adds an arabinose unit to the 4-phosphate of lipid A molecules. The Salmonella typhimurium enzyme can add arabinose units to both positions. Formerly Ec 2.4.2.n1.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are no PDB entries in enzyme class E.C.2.4.2.43