_EC 2.4.2.22 Xanthine phosphoribosyltransferase. 9 PDB entries  
EC 2.-.-.- Transferases. [19,180 PDB entries]
EC 2.4.-.- Glycosyltransferases. [2,021 PDB entries]
EC 2.4.2.- Pentosyltransferases. [955 PDB entries]
EC 2.4.2.22 Xanthine phosphoribosyltransferase. [9 PDB entries]    
1a95

Reaction: Xmp + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + xanthine.
 


XMP
+
diphosphate
=
5-phospho-alpha-D-ribose 1-diphosphate
+
xanthine
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): Xan phosphoribosyltransferase. Xanthine-guanine phosphoribosyltransferase. Xanthosine 5'-phosphate pyrophosphorylase. Xanthylate pyrophosphorylase. Xanthylic pyrophosphorylase. Xmp pyrophosphorylase.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 9 PDB entries in enzyme class E.C.2.4.2.22

  PDB code Protein
1a95
Xprtase from e. Coli complexed with mg:cprpp and guanine
Source: Escherichia coli. Organism_taxid: 562. Cell_line: hb101. Atcc: atcc 37145. Cellular_location: cytoplasm. Gene: gpt. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_atcc_number: 87050.
Chains: A, B, C, D (145 residues) CATH domain: 3.40.50.2020
Bound ligands:   Het Group PCP is 91.00% similar to enzyme product 5-phospho-alpha-D-ribose 1-diphosphate
  Het Group GUN is 83.00% similar to enzyme product Xanthine
1a96
Xprtase from e. Coli with bound cprpp and xanthine
Source: Escherichia coli. Organism_taxid: 562. Cell_line: hb101. Atcc: atcc 37145. Collection: atcc 37145. Cellular_location: cytoplasm. Gene: gpt. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (145 residues) CATH domain: 3.40.50.2020
Bound ligands:   Het Group PCP is 91.00% similar to enzyme product 5-phospho-alpha-D-ribose 1-diphosphate
  Het Group XAN corresponds to enzyme product Xanthine
1a97
Xprtase from e. Coli complexed with gmp
Source: Escherichia coli. Organism_taxid: 562. Strain: hb101. Atcc: atcc 37145. Collection: atcc 37145. Cellular_location: cytoplasm. Gene: gpt. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (144 residues) CATH domain: 3.40.50.2020
Bound ligand:   Het Group 5GP is 92.00% similar to enzyme reactant xanthosine 5'-phosphate
1a98
Xprtase from e. Coli complexed with gmp
Source: Escherichia coli. Organism_taxid: 562. Strain: hb101. Atcc: atcc 37145. Collection: atcc 37145. Cellular_location: cytoplasm. Gene: gpt. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (129 residues) CATH domain: 3.40.50.2020
1nul
Xprtase from e. Coli
Source: Escherichia coli. Organism_taxid: 562
Chains: A, B (142 residues) CATH domain: 3.40.50.2020
1y0b
Crystal structure of xanthine phosphoribosyltransferase from subtilis.
Source: Bacillus subtilis. Organism_taxid: 1423. Gene: xpt. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chains: A, B, C, D (193 residues) CATH domain: 3.40.50.2020
Bound ligand:   Het Group G4P is 79.31% similar to enzyme reactant xanthosine
2fxv
Bacillus subtilis xanthine phosphoribosyltransferase in comp guanosine 5'-monophosphate (gmp)
Source: Bacillus subtilis. Organism_taxid: 1423. Gene: xpt. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (190 residues) CATH domain: 3.40.50.2020
Bound ligand:   Het Group 5GP is 92.00% similar to enzyme reactant xanthosine
4jit
Crystal structure of e. Coli xgprt in complex with (s)-3-(gu yl)pyrrolidin-n-ylacetylphosphonic acid
Source: Escherichia coli. Organism_taxid: 1110693. Strain: str. K-12 substr. Mds42. Gene: gpt, ecmds42_0227. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D (149 residues) CATH domain: 3.40.50.2020
Bound ligand:   Het Group 3ZF is 41.67% similar to enzyme product xanthine
4jls
Crystal structure of e. Coli xgprt in complex with (3r,4s)-4 9-yl)-3-hydroxypyrrolidin-1-n-ylacetylphosphonic acid
Source: Escherichia coli. Organism_taxid: 1110693. Strain: str. K-12 substr. Mds42. Gene: gpt, ecmds42_0227. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D, E, H, I, J (133 residues) CATH domain: 3.40.50.2020
Bound ligand:   Het Group 3ZE is 41.18% similar to enzyme reactant xanthosine