_EC 2.4.1.79 Globotriaosylceramide 3-beta-N-acetylgalactosaminyltransferase. 0 PDB entries  
EC 2.-.-.- Transferases. [17,772 PDB entries]
EC 2.4.-.- Glycosyltransferases. [1,895 PDB entries]
EC 2.4.1.- Hexosyltransferases. [932 PDB entries]
EC 2.4.1.79 Globotriaosylceramide 3-beta-N-acetylgalactosaminyltransferase. [-]    

Reaction: UDP-N-acetyl-alpha-D-galactosamine + alpha-D-galactosyl-(1->4)-beta-D- galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide = Udp + N-acetyl-beta- D-galactosaminyl-(1->3)-alpha-D-galactosyl-(1->4)-beta-D-galactosyl- (1->4)-beta-D-glucosyl-(1<->1)-ceramide.
 

UDP-N-acetyl-alpha-D-galactosamine
+ alpha-D-galactosyl-(1->4)-beta-D- galactosyl-(1->4)-beta-D-glucosyl-(1<->1)-ceramide
=
UDP
+ N-acetyl-beta- D-galactosaminyl-(1->3)-alpha-D-galactosyl-(1->4)-beta-D-galactosyl- (1->4)-beta-D-glucosyl-(1<->1)-ceramide
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): Beta-3GalNAc-T1. Galactosylgalactosylglucosylceramide beta-D- acetylgalactosaminyltransferase. Globoside synthase. Globoside synthetase. Uridine diphosphoacetylgalactosamine-galactosylgalactosylglucosylceramide acetylgalactosaminyltransferase.
Cofactor(s): Manganese.
Comments: Globoside is a neutral glycosphingolipid in human erythrocytes and has blood-group-P-antigen activity. UDP-GalNAc is the only sugar donor that is used efficiently by the enzyme: UDP-Gal and UDP-GlcNAc result in very low enzyme activity. Lactosylceramide, globoside and gangliosides GM3 and GD3 are not substrates.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are no PDB entries in enzyme class E.C.2.4.1.79