_EC 2.4.1.37 Fucosylgalactoside 3-alpha-galactosyltransferase. 101 PDB entries  
EC 2.-.-.- Transferases. [17,806 PDB entries]
EC 2.4.-.- Glycosyltransferases. [1,911 PDB entries]
EC 2.4.1.- Hexosyltransferases. [931 PDB entries]
EC 2.4.1.37 Fucosylgalactoside 3-alpha-galactosyltransferase. [101 PDB entries]    
1lz0

Reaction: UDP-alpha-D-galactose + alpha-L-fucosyl-(1->2)-D-galactosyl-R = Udp + alpha-D-galactosyl-(1->3)-(alpha-L-fucosyl-(1->2))-D-galactosyl-R.
 

UDP-alpha-D-galactose
+
alpha-L-fucosyl-(1->2)-D-galactosyl-R
=
UDP
+ alpha-D-galactosyl-(1->3)-(alpha-L-fucosyl-(1->2))-D-galactosyl-R
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): [Blood group substance] alpha-galactosyltransferase. B transferase. Blood-group substance alpha-dependent galactosyltransferase. Blood-group substance B-dependent galactosyltransferase. Fucosylglycoprotein 3-alpha-galactosyltransferase. Glycoprotein-fucosylgalactoside alpha-galactosyltransferase. Histo-blood group B transferase. Histo-blood substance alpha-dependent galactosyltransferase. UDPgalactose:glycoprotein-alpha-L-fucosyl-(1,2)-D-galactose 3-alpha-D- galactosyltransferase.
Comments: Acts on blood group substance, and can use a number of 2-fucosyl- galactosides as acceptors.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 101 PDB entries in enzyme class E.C.2.4.1.37

  PDB code Protein
1lz0
Glycosyltransferase a
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (265 residues) CATH domain: 3.90.550.10
1lz7
Glycosyltransferase b
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (266 residues) CATH domain: 3.90.550.10
1lzi
Glycosyltransferase a + udp + h antigen acceptor
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (264 residues) CATH domain: 3.90.550.10
Bound ligands:   Het Group BHG is 64.00% similar to enzyme reactant alpha-L-fucosyl-(1->2)-D-galactosyl-R
  Het Group UDP corresponds to enzyme product UDP
1lzj
Glycosyltransferase b + udp + h antigen acceptor
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (263 residues) CATH domain: 3.90.550.10
Bound ligands:   Het Group BHG is 64.00% similar to enzyme reactant alpha-L-fucosyl-(1->2)-D-galactosyl-R
  Het Group UDP corresponds to enzyme product UDP
1r7t
Glycosyltransferase a in complex with 3-deoxy-acceptor analo inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (263 residues) CATH domain: 3.90.550.10
Bound ligand:   Het Group DLG is 60.00% similar to enzyme reactant alpha-L-fucosyl-(1->2)-D-galactosyl-R
1r7u
Glycosyltransferase b in complex with 3-deoxy-acceptor analo inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (264 residues) CATH domain: 3.90.550.10
Bound ligand:   Het Group DLG is 60.00% similar to enzyme reactant alpha-L-fucosyl-(1->2)-D-galactosyl-R
1r7v
Glycosyltransferase a in complex with 3-amino-acceptor analo inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (263 residues) CATH domain: 3.90.550.10
Bound ligand:   Het Group AIG is 57.69% similar to enzyme reactant alpha-L-fucosyl-(1->2)-D-galactosyl-R
1r7x
Glycosyltransferase b in complex with 3-amino-acceptor analo inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (263 residues) CATH domain: 3.90.550.10
Bound ligand:   Het Group AIG is 57.69% similar to enzyme reactant alpha-L-fucosyl-(1->2)-D-galactosyl-R
1r7y
Glycosyltransferase a in complex with 3-amino-acceptor analo inhibitor and uridine diphosphate
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (264 residues) CATH domain: 3.90.550.10
Bound ligands:   Het Group AIG is 57.69% similar to enzyme reactant alpha-L-fucosyl-(1->2)-D-galactosyl-R
  Het Group UDP corresponds to enzyme product UDP
1r80
Glycosyltransferase b in complex with 3-amino-acceptor analo inhibitor and uridine diphosphate
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (266 residues) CATH domain: 3.90.550.10
Bound ligands:   Het Group AIG is 57.69% similar to enzyme reactant alpha-L-fucosyl-(1->2)-D-galactosyl-R
  Het Group UDP corresponds to enzyme product UDP
1r81
Glycosyltransferase a in complex with 3-amino-acceptor analo inhibitor and uridine diphosphate-n-acetyl-galactose
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (266 residues) CATH domain: 3.90.550.10
Bound ligands:   Het Group AIG is 57.69% similar to enzyme reactant alpha-L-fucosyl-(1->2)-D-galactosyl-R
  Het Group UD2 corresponds to enzyme product UDP
1r82
Glycosyltransferase b in complex with 3-amino-acceptor analo inhibitor, and uridine diphosphate-galactose
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (263 residues) CATH domain: 3.90.550.10
Bound ligands:   Het Group AOG is 53.57% similar to enzyme reactant alpha-L-fucosyl-(1->2)-D-galactosyl-R
  Het Group GDU corresponds to enzyme product UDP
1wsz
Mutant human abo(h) blood group transferase a
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (263 residues) CATH domain: 3.90.550.10
1wt0
Mutant human abo(h) blood group glycosyltransferase a
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (263 residues) CATH domain: 3.90.550.10
1wt1
Mutant abo(h) blood group glycosyltransferase with bound udp acceptor
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (263 residues) CATH domain: 3.90.550.10
Bound ligands:   Het Group BHG is 64.00% similar to enzyme reactant alpha-L-fucosyl-(1->2)-D-galactosyl-R
  Het Group UDP corresponds to enzyme product UDP
1wt2
Mutant human abo(h) blood group glycosyltransferase a with b and inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (263 residues) CATH domain: 3.90.550.10
Bound ligands:   Het Group DLG is 60.00% similar to enzyme reactant alpha-L-fucosyl-(1->2)-D-galactosyl-R
  Het Group UDP corresponds to enzyme product UDP
1wt3
Mutant human abo(h) blood group glycosyltransferase with bou acceptor
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (263 residues) CATH domain: 3.90.550.10
Bound ligands:   Het Group BHG is 64.00% similar to enzyme reactant alpha-L-fucosyl-(1->2)-D-galactosyl-R
  Het Group UDP corresponds to enzyme product UDP
1xz6
Mutant abo(h) blood group glycosyltransferase a
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: abo. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (263 residues) CATH domain: 3.90.550.10
1zhj
Crystal structure of human n-acetylgalactosaminyltransferase complexed with galactose
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: abo. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (272 residues) CATH domain: 3.90.550.10
Bound ligand:   Het Group GAL is 52.17% similar to enzyme reactant alpha-L-fucosyl-(1->2)-D-galactosyl-R
1zi1
Crystal structure of human n-acetylgalactosaminyltransferase complexed with lactose
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: abo. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (263 residues) CATH domain: 3.90.550.10
1zi3
Crystal structure of human n-acetylgalactosaminyltransferase complexed with n-acetyllactosamine
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: abo. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (263 residues) CATH domain: 3.90.550.10
Bound ligand:   Het Group NLC is 63.33% similar to enzyme reactant alpha-L-fucosyl-(1->2)-D-galactosyl-R
1zi4
Crystal structure of human n-acetylgalactosaminyltransferase complexed with h type ii trisaccharide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: abo. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (264 residues) CATH domain: 3.90.550.10
Bound ligand:   Het Group DR2 is 59.46% similar to enzyme reactant alpha-L-fucosyl-(1->2)-D-galactosyl-R
1zi5
Crystal structure of human n-acetylgalactosaminyltransferase complexed with h type i trisaccharide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: abo. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (264 residues) CATH domain: 3.90.550.10
Bound ligands:   Het Group DR3 is 59.46% similar to enzyme reactant alpha-L-fucosyl-(1->2)-D-galactosyl-R
  Het Group UDP corresponds to enzyme product UDP
1ziz
Crystal structure of human galactosyltransferase (gtb) compl galactose
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (263 residues) CATH domain: 3.90.550.10
Bound ligand:   Het Group GAL is 52.17% similar to enzyme reactant alpha-L-fucosyl-(1->2)-D-galactosyl-R
1zj0
Crystal structure of human galactosyltransferase (gtb) compl lactose
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (265 residues) CATH domain: 3.90.550.10
Bound ligand:   Het Group LAT is 76.92% similar to enzyme reactant alpha-L-fucosyl-(1->2)-D-galactosyl-R
1zj1
Crystal structure of human galactosyltransferase (gtb) compl n-acetyllactosamine
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (263 residues) CATH domain: 3.90.550.10
Bound ligand:   Het Group NLC is 63.33% similar to enzyme reactant alpha-L-fucosyl-(1->2)-D-galactosyl-R
1zj2
Crystal structure of human galactosyltransferase (gtb) compl h type i trisaccharide
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (263 residues) CATH domain: 3.90.550.10
Bound ligands:   Het Group DR3 is 59.46% similar to enzyme reactant alpha-L-fucosyl-(1->2)-D-galactosyl-R
  Het Group UDP corresponds to enzyme product UDP
1zj3
Crystal structure of human galactosyltransferase (gtb) compl h type ii trisaccharide
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (263 residues) CATH domain: 3.90.550.10
Bound ligand:   Het Group DR2 is 59.46% similar to enzyme reactant alpha-L-fucosyl-(1->2)-D-galactosyl-R
1zjo
Crystal structure of human n-acetylgalactosaminyltransferase complexed with galactose-grease
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: abo. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (263 residues) CATH domain: 3.90.550.10
Bound ligands:   Het Group DR4 is 51.61% similar to enzyme reactant alpha-L-fucosyl-(1->2)-D-galactosyl-R
  Het Group UDP corresponds to enzyme product UDP
1zjp
Crystal structure of human galactosyltransferase (gtb) compl galactose-grease
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (261 residues) CATH domain: 3.90.550.10
Bound ligands:   Het Group DR4 is 51.61% similar to enzyme reactant alpha-L-fucosyl-(1->2)-D-galactosyl-R
  Het Group UDP corresponds to enzyme product UDP
2a8u
Crystal structure of human galactosyltransferase (gtb) compl beta-methyl lactoside
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (263 residues) CATH domain: 3.90.550.10
Bound ligands:   Het Group DR5 is 74.07% similar to enzyme reactant alpha-L-fucosyl-(1->2)-D-galactosyl-R
  Het Group UDP corresponds to enzyme product UDP
2a8w
Crystal structure of human n-acetylgalactosaminyltransferase complexed with beta-methyllactoside
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: abo. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (263 residues) CATH domain: 3.90.550.10
Bound ligand:   Het Group UDP corresponds to enzyme product UDP
2i7b
Structure of the naturally occuring mutant of human abo(h) b b glycosyltransferase: gtb/a268t
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: abo. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chain: A (262 residues) CATH domain: 3.90.550.10
2o1f
Natural occuring mutation of human abo(h) galactosyltransfer gtb/m214r
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: abo. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chain: A (264 residues) CATH domain: 3.90.550.10
2o1g
Natural occurring mutant of human abo(h) galactosyltransfera gtb/m214t
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: abo. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chain: A (264 residues) CATH domain: 3.90.550.10
2o1h
Naturally occurring mutation of humna abo(h) galactosyltrans complex with udp: gtb/m214t_udp
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: abo. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chain: A (262 residues) CATH domain: 3.90.550.10
Bound ligand:   Het Group UDP corresponds to enzyme product UDP
2pgv
Gtb c209a
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: abo. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chain: A (271 residues) CATH domain: 3.90.550.10
2pgy
Gtb c209a, no hg
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: abo. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chain: A (272 residues) CATH domain: 3.90.550.10
2rit
Unliganded b-specific-1,3-galactosyltransferase (gtb)
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: abo. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (280 residues) CATH domain: 3.90.550.10
2rix
B-specific-1,3-galactosyltransferase)(gtb) + udp
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: abo. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (276 residues) CATH domain: 3.90.550.10
Bound ligand:   Het Group UDP corresponds to enzyme product UDP
2riy
B-specific-1,3-galactosyltransferase (gtb)+h-antigen accepto
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: abo. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (275 residues) CATH domain: 3.90.550.10
Bound ligand:   Het Group BHE is 75.86% similar to enzyme reactant alpha-L-fucosyl-(1->2)-D-galactosyl-R
2riz
Unliganded b-specific-1,3-galactosyltransferase g176r mutant
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: abo. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (284 residues) CATH domain: 3.90.550.10
2rj0
B-specific alpha-1,3-galactosyltransferase g176r mutant + ud
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: abo. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (281 residues) CATH domain: 3.90.550.10
Bound ligand:   Het Group UDP corresponds to enzyme product UDP
2rj1
B-specific alpha-1,3-galactosyltransferase (gtb) g176r mutan h-antigen disaccharide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: abo. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (291 residues) CATH domain: 3.90.550.10
Bound ligands:   Het Group BHE is 75.86% similar to enzyme reactant alpha-L-fucosyl-(1->2)-D-galactosyl-R
  Het Group UDP corresponds to enzyme product UDP
2rj4
B-specific alpha-1,3-galactosyltransferase \ g176r +udp+ada
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: abo. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (290 residues) CATH domain: 3.90.550.10
Bound ligands:   Het Group AD7 is 66.67% similar to enzyme reactant alpha-L-fucosyl-(1->2)-D-galactosyl-R
  Het Group UDP corresponds to enzyme product UDP
2rj5
B-specific alpha-1,3-galactosyltransferase g176r s235g mutan +udp
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: abo. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (282 residues) CATH domain: 3.90.550.10
Bound ligand:   Het Group UDP corresponds to enzyme product UDP
2rj6
B-specific alpha-1,3-galactosyltransferase g176r s235g mutan h-antigen disaccharide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: abo. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (284 residues) CATH domain: 3.90.550.10
Bound ligand:   Het Group BHE is 75.86% similar to enzyme reactant alpha-L-fucosyl-(1->2)-D-galactosyl-R
2rj7
B-specific alpha-1,3-galactosyltransferase g176r s235g mutan udpgal + deoxy-acceptor
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: abo. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (292 residues) CATH domain: 3.90.550.10
Bound ligands:   Het Group GDU corresponds to enzyme reactant UDP-galactose
  Het Group DA8 is 72.41% similar to enzyme reactant alpha-L-fucosyl-(1->2)-D-galactosyl-R
2rj8
B-specific alpha-1,3-galactosyltransferase (gtb) +udp+ h-ant disaccharide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: abo. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (286 residues) CATH domain: 3.90.550.10
Bound ligands:   Het Group BHE is 75.86% similar to enzyme reactant alpha-L-fucosyl-(1->2)-D-galactosyl-R
  Het Group UDP corresponds to enzyme product UDP
2rj9
B-specific alpha-1,3-galactosyltransferase (gtb) + udp+ amin acceptor
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: abo. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (279 residues) CATH domain: 3.90.550.10
Bound ligands:   Het Group AD7 is 66.67% similar to enzyme reactant alpha-L-fucosyl-(1->2)-D-galactosyl-R
  Het Group UDP corresponds to enzyme product UDP
2y7a
Crystal structure of unliganded gtb p156l
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D (277 residues) CATH domain: 3.90.550.10
Bound ligand:   Het Group UDP corresponds to enzyme product UDP
3i0c
Crystal structure of gtb c80s/c196s unliganded
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: abo, gtb. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (271 residues) CATH domain: 3.90.550.10
3i0d
Crystal structure of gtb c80s/c196s + udp
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gtb. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (264 residues) CATH domain: 3.90.550.10
3i0e
Crystal structure of gtb c80s/c196s + h-antigen
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gtb. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (273 residues) CATH domain: 3.90.550.10
3i0f
Crystal structure of gtb c80s/c196s + udp + h antigen
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gtb. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (268 residues) CATH domain: 3.90.550.10
3i0g
Crystal structure of gtb c80s/c196s + da + udp-gal
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gtb. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (268 residues) CATH domain: 3.90.550.10
3i0h
Crystal structure of gtb c80s/c196s/c209s unliganded
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gtb. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (274 residues) CATH domain: 3.90.550.10
3i0i
Crystal structure of gtb c80s/c196s/c209s + udp
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gtb. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: X (272 residues) CATH domain: 3.90.550.10
3i0j
Crystal structure of gtb c80s/c196s/c209s + h antigen
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gtb. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (270 residues) CATH domain: 3.90.550.10
Bound ligand:   Het Group BHG is 64.00% similar to enzyme reactant alpha-L-fucosyl-(1->2)-D-galactosyl-R
3i0k
Crystal structure of gtb c80s/c196s/c209s + udp + h antigen
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gtb. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (267 residues) CATH domain: 3.90.550.10
3i0l
Crystal structure of gtb c80s/c196s/c209s + da + udp-gal
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gtb. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (272 residues) CATH domain: 3.90.550.10
3ioh
Crystal structure of the fucosylgalactoside alpha n- acetylgalactosaminyltransferase (gta, cisab mutant l266g, g
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: abo. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chain: A (283 residues) CATH domain: 3.90.550.10
3ioi
Crystal structure of the fucosylgalactoside alpha n- acetylgalactosaminyltransferase (gta, cisab mutant l266g, g complex with a novel udp-gal derived inhibitor (1gw)
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: abo. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chain: A (274 residues) CATH domain: 3.90.550.10
Bound ligand:   Het Group 1GW is 83.00% similar to enzyme reactant UDP-galactose
3ioj
Crystal structure of the fucosylgalactoside alpha n- acetylgalactosaminyltransferase (gta, cisab mutant l266g, g complex with udp
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: abo. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chains: A, B (284 residues) CATH domain: 3.90.550.10
Bound ligand:   Het Group UDP corresponds to enzyme product UDP
3sx3
Crystal structure of aabb+udp+gal with glycerol as the cryop
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: abo. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chain: A (291 residues) CATH domain: 3.90.550.10
Bound ligands:   Het Group GAL is 52.17% similar to enzyme reactant alpha-L-fucosyl-(1->2)-D-galactosyl-R
  Het Group UDP corresponds to enzyme product UDP
3sx5
Crystal structure of aabb+udp+gal with mpd as the cryoprotec
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: abo. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chain: A (286 residues) CATH domain: 3.90.550.10
Bound ligands:   Het Group GAL is 52.17% similar to enzyme reactant alpha-L-fucosyl-(1->2)-D-galactosyl-R
  Het Group UDP corresponds to enzyme product UDP
3sx7
Crystal structure of abba+udp+gal with glycerol as the cryop
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: abo. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chain: A (285 residues) CATH domain: 3.90.550.10
Bound ligands:   Het Group GAL is 52.17% similar to enzyme reactant alpha-L-fucosyl-(1->2)-D-galactosyl-R
  Het Group UDP corresponds to enzyme product UDP
3sx8
Crystal structure of abba+udp+gal with mpd as the cryoprotec
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: abo. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chain: A (274 residues) CATH domain: 3.90.550.10
Bound ligands:   Het Group GAL is 52.17% similar to enzyme reactant alpha-L-fucosyl-(1->2)-D-galactosyl-R
  Het Group UDP corresponds to enzyme product UDP
3sxa
Crystal structure of abbb+udp+gal with glycerol as the cryop
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: abo. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chain: A (291 residues) CATH domain: 3.90.550.10
Bound ligands:   Het Group GAL is 52.17% similar to enzyme reactant alpha-L-fucosyl-(1->2)-D-galactosyl-R
  Het Group UDP corresponds to enzyme product UDP
3sxb
Crystal structure of abbb+udp+gal with mpd as the cryoprotec
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: abo. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chain: A (275 residues) CATH domain: 3.90.550.10
Bound ligands:   Het Group GAL is 52.17% similar to enzyme reactant alpha-L-fucosyl-(1->2)-D-galactosyl-R
  Het Group UDP corresponds to enzyme product UDP
3sxc
Crystal structure of bbbb+udp+gal with glycerol as the cryop
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: abo. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chain: A (275 residues) CATH domain: 3.90.550.10
Bound ligands:   Het Group GAL is 52.17% similar to enzyme reactant alpha-L-fucosyl-(1->2)-D-galactosyl-R
  Het Group UDP corresponds to enzyme product UDP
3sxd
Crystal structure of bbbb+udp+gal with mpd as the cryoprotec
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: abo. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chain: A (272 residues) CATH domain: 3.90.550.10
Bound ligands:   Het Group GAL is 52.17% similar to enzyme reactant alpha-L-fucosyl-(1->2)-D-galactosyl-R
  Het Group UDP corresponds to enzyme product UDP
3sxe
Crystal structure of aaaa+udp+gal with glycerol as the cryop
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: abo. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chain: A (293 residues) CATH domain: 3.90.550.10
Bound ligand:   Het Group UDP corresponds to enzyme product UDP
3sxg
Crystal structure of aaaa+udp+gal with mpd as the cryoprotec
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: abo. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chain: A (291 residues) CATH domain: 3.90.550.10
Bound ligand:   Het Group UDP corresponds to enzyme product UDP
3u0x
Crystal structure of the b-specific-1,3-galactosyltransferas complex with compound 382
Source: Homo sapiens. Human. Organism_taxid: 9606. Strain: human. Gene: abo. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chains: A, B (290 residues) CATH domain: 3.90.550.10
3u0y
Crystal structure of the fucosylgalactoside alpha n- acetylgalactosaminyltransferase (gta, cisab mutant l266g, g complex with compound 382 and udp
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: abo. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chains: A, B (288 residues) CATH domain: 3.90.550.10
3v0l
Crystal structure of the fucosylgalactoside alpha n- acetylgalactosaminyltransferase (gta, cisab mutant l266g, g complex with a novel udp-gal derived inhibitor (2gw)
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ab0, abo. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chain: A (278 residues) CATH domain: 3.90.550.10
Bound ligand:   Het Group 2GW is 59.52% similar to enzyme product UDP
3v0m
Crystal structure of the fucosylgalactoside alpha n- acetylgalactosaminyltransferase (gta, cisab mutant l266g, g complex with a novel udp-gal derived inhibitor (5gw) and h- acceptor
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ab0, abo. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chains: A, B (289 residues) CATH domain: 3.90.550.10
Bound ligands:   Het Group BHE is 70.97% similar to enzyme reactant alpha-L-fucosyl-(1->2)-D-galactosyl-R
  Het Group 5GW is 80.65% similar to enzyme product UDP
3v0n
Crystal structure of the fucosylgalactoside alpha n- acetylgalactosaminyltransferase (gta, cisab mutant l266g, g complex with a novel udp-galnac derived inhibitor (3gw and
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ab0, abo. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chain: B ( residues)
3v0o
Crystal structure of the fucosylgalactoside alpha n- acetylgalactosaminyltransferase (gta, cisab mutant l266g, g complex with a novel udp-galnac derived inhibitor (4gw) and acceptor
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ab0, abo. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chains: A, B (290 residues) CATH domain: 3.90.550.10
3v0p
Crystal structure of the fucosylgalactoside alpha n- acetylgalactosaminyltransferase (gta, cisab mutant l266g, g complex with a novel udp-gal derived inhibitor (4gw) and h- acceptor
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ab0, abo. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chain: B ( residues)
Bound ligands:   Het Group BHE is 70.97% similar to enzyme reactant alpha-L-fucosyl-(1->2)-D-galactosyl-R
  Het Group 4GW is 78.12% similar to enzyme product UDP
3v0q
Crystal structure of the fucosylgalactoside alpha n- acetylgalactosaminyltransferase (gta, cisab mutant l266g, g complex with udp and h-antigen acceptor
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: ab0, abo. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chains: A, B (297 residues) CATH domain: 3.90.550.10
Bound ligands:   Het Group BHE is 70.97% similar to enzyme reactant alpha-L-fucosyl-(1->2)-D-galactosyl-R
  Het Group UDP corresponds to enzyme product UDP
3zgf
Crystal structure of the fucosylgalactoside alpha n- acetylgalactosaminyltransferase (gta, cisab mutant l266g, g268a) in complex with in complex with npe caged udp-gal ( p2(1)2(1)2(1) space group)
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 511693. Expression_system_variant: gold.
Chains: A, B (291 residues) CATH domain: 3.90.550.10
3zgg
Crystal structure of the fucosylgalactoside alpha n- acetylgalactosaminyltransferase (gta, cisab mutant l266g, g in complex with npe caged udp-gal (c222(1) space group)
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 511693. Expression_system_variant: gold.
Chain: A (274 residues) CATH domain: 3.90.550.10
4c2s
Crystal structure of the fucosylgalactoside alpha n- acetylgalactosaminyltransferase (gta p156l mutant) in complex with udp and deoxy-h-antigen acceptor
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chains: A, B (291 residues) CATH domain: 3.90.550.10
Bound ligands:   Het Group DLG is 60.00% similar to enzyme reactant alpha-L-fucosyl-(1->2)-D-galactosyl-R
  Het Group UDP corresponds to enzyme product UDP
4fqw
Crystal structure of aaaa+udp+gal at ph 5.0 with mpd as the cryoprotectant
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: abo. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (271 residues) CATH domain: 3.90.550.10
Bound ligands:   Het Group GAL is 52.17% similar to enzyme reactant alpha-L-fucosyl-(1->2)-D-galactosyl-R
  Het Group UDP corresponds to enzyme product UDP
4fra
Crystal structure of abba+udp+gal at ph 5.0 with mpd as the cryoprotectant
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: abo. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (272 residues) CATH domain: 3.90.550.10
Bound ligands:   Het Group GAL is 52.17% similar to enzyme reactant alpha-L-fucosyl-(1->2)-D-galactosyl-R
  Het Group UDP corresponds to enzyme product UDP
4frb
Crystal structure of abba+udp+gal at ph 8.0 with mpd as the cryoprotectant
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: abo. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (282 residues) CATH domain: 3.90.550.10
Bound ligands:   Het Group GAL is 52.17% similar to enzyme reactant alpha-L-fucosyl-(1->2)-D-galactosyl-R
  Het Group UDP corresponds to enzyme product UDP
4frd
Crystal structure of abba+udp+gal at ph 9.0 with mpd as the cryoprotectant
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: abo. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (282 residues) CATH domain: 3.90.550.10
Bound ligands:   Het Group GAL is 52.17% similar to enzyme reactant alpha-L-fucosyl-(1->2)-D-galactosyl-R
  Het Group UDP corresponds to enzyme product UDP
4fre
Crystal structure of bbbb+udp+gal at ph 6.5 with mpd as the cryoprotectant
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: abo. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (264 residues) CATH domain: 3.90.550.10
Bound ligands:   Het Group GAL is 52.17% similar to enzyme reactant alpha-L-fucosyl-(1->2)-D-galactosyl-R
  Het Group UDP corresponds to enzyme product UDP
4frh
Crystal structure of bbbb+udp+gal at ph 7.5 with mpd as the cryoprotectant
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: abo. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (271 residues) CATH domain: 3.90.550.10
Bound ligands:   Het Group GAL is 52.17% similar to enzyme reactant alpha-L-fucosyl-(1->2)-D-galactosyl-R
  Het Group UDP corresponds to enzyme product UDP
4frl
Crystal structure of bbbb+udp+gal at ph 8.0 with mpd as the cryoprotectant
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: abo. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (276 residues) CATH domain: 3.90.550.10
Bound ligands:   Het Group GAL is 52.17% similar to enzyme reactant alpha-L-fucosyl-(1->2)-D-galactosyl-R
  Het Group UDP corresponds to enzyme product UDP
4frm
Crystal structure of bbbb+udp+gal at ph 7.0 with mpd as the cryoprotectant
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: abo. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (264 residues) CATH domain: 3.90.550.10
Bound ligands:   Het Group GAL is 52.17% similar to enzyme reactant alpha-L-fucosyl-(1->2)-D-galactosyl-R
  Het Group UDP corresponds to enzyme product UDP
4fro
Crystal structure of bbbb+udp+gal at ph 9.0 with mpd as the cryoprotectant
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: abo. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (276 residues) CATH domain: 3.90.550.10
Bound ligands:   Het Group GAL is 52.17% similar to enzyme reactant alpha-L-fucosyl-(1->2)-D-galactosyl-R
  Het Group UDP corresponds to enzyme product UDP
4frp
Crystal structure of bbbb+udp+gal at ph 8.5 with mpd as the cryoprotectant
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: abo. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (274 residues) CATH domain: 3.90.550.10
Bound ligands:   Het Group GAL is 52.17% similar to enzyme reactant alpha-L-fucosyl-(1->2)-D-galactosyl-R
  Het Group UDP corresponds to enzyme product UDP
4frq
Crystal structure of bbbb+udp+gal at ph 9.5 with mpd as the cryoprotectant
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: abo. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (277 residues) CATH domain: 3.90.550.10
Bound ligands:   Het Group GAL is 52.17% similar to enzyme reactant alpha-L-fucosyl-(1->2)-D-galactosyl-R
  Het Group UDP corresponds to enzyme product UDP
4gbp
Crystal structure of bbbb+udp+gal at ph 10 with mpd as the cryoprotectant
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: abo. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (279 residues) CATH domain: 3.90.550.10
Bound ligands:   Het Group GAL is 52.17% similar to enzyme reactant alpha-L-fucosyl-(1->2)-D-galactosyl-R
  Het Group UDP corresponds to enzyme product UDP
4kc1
Structure of the blood group glycosyltransferase aaglyb in c with a pyridine inhibitor as a neutral pyrophosphate surrog
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: abo. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (289 residues) CATH domain: 3.90.550.10
4kc2
Structure of the blood group glycosyltransferase aaglyb in c with a pyridine inhibitor as a neutral pyrophosphate surrog
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: abo. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (289 residues) CATH domain: 3.90.550.10
4kc4
Structure of the blood group glycosyltransferase aaglyb in c with a pyridine inhibitor as a neutral pyrophosphate surrog
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: abo. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (289 residues) CATH domain: 3.90.550.10
4kxo
Crystal structure of bbbb at ph 10.0 with mpd as the cryopro
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: abo. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chain: A (266 residues) CATH domain: 3.90.550.10