_EC 2.4.1.19 Cyclomaltodextrin glucanotransferase. 50 PDB entries  
EC 2.-.-.- Transferases. [17,949 PDB entries]
EC 2.4.-.- Glycosyltransferases. [1,920 PDB entries]
EC 2.4.1.- Hexosyltransferases. [944 PDB entries]
EC 2.4.1.19 Cyclomaltodextrin glucanotransferase. [50 PDB entries]    
1a47

Reaction: Cyclizes part of a (1->4)-alpha-D-glucan chain by formation of a (1->4)- alpha-D-glucosidic bond.
Other name(s): Bacillus macerans amylase. Cyclodextrin glucanotransferase. Cyclodextrin glycosyltransferase.
Comments: Cyclomaltodextrins (Schardinger dextrins) of various sizes (6, 7, 8, etc. glucose units) are formed reversibly from starch and similar substrates. Also disproportionates linear maltodextrins without cyclizing (cf. Ec 2.4.1.25).
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There are 50 PDB entries in enzyme class E.C.2.4.1.19

  PDB code Protein
1a47
Cgtase from thermoanaerobacterium thermosulfurigenes em1 in complex with a maltohexaose inhibitor
Source: Thermoanaerobacterium thermosulfurigenes. Organism_taxid: 33950. Strain: em1. Cellular_location: extracellular. Gene: amya. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (683 residues) CATH domains: 3.20.20.80 2.60.40.1180 2.60.40.10 2.60.40.10
1cdg
Nucleotide sequence and x-ray structure of cyclodextrin glycosyltransferase from bacillus circulans strain 251 in a maltose-dependent crystal form
Source: Bacillus circulans. Organism_taxid: 1397
Chain: A (686 residues) CATH domains: 3.20.20.80 2.60.40.1180 2.60.40.10 2.60.40.10
1cgt
Structure of cyclodextrin glycosyltransferase refined at 2.0 angstroms resolution
Source: Bacillus circulans. Organism_taxid: 1397
Chain: A (684 residues) CATH domains: 3.20.20.80 2.60.40.1180 2.60.40.10 2.60.40.10
1cgu
Catalytic center of cyclodextrin glycosyltransferase derived from x-ray structure analysis combined with site- directed mutagenesis
Source: Bacillus circulans. Organism_taxid: 1397
Chain: A (684 residues) CATH domains: 3.20.20.80 2.60.40.1180 2.60.40.10 2.60.40.10
1cgv
Site directed mutations of the active site residue tyrosine cyclodextrin glycosyltransferase from bacillus circulans st affecting activity and product specificity
Source: Bacillus circulans. Organism_taxid: 1397
Chain: A (686 residues) CATH domains: 3.20.20.80 2.60.40.1180 2.60.40.10 2.60.40.10
1cgw
Site directed mutations of the active site residue tyrosine cyclodextrin glycosyltransferase from bacillus circulans st affecting activity and product specificity
Source: Bacillus circulans. Organism_taxid: 1397
Chain: A (686 residues) CATH domains: 3.20.20.80 2.60.40.1180 2.60.40.10 2.60.40.10
1cgx
Site directed mutations of the active site residue tyrosine 195 of cyclodextrin glyxosyltransferase from bacillus circulans strain 251 affecting activity and product specificity
Source: Bacillus circulans. Organism_taxid: 1397
Chain: A (686 residues) CATH domains: 3.20.20.80 2.60.40.1180 2.60.40.10 2.60.40.10
1cgy
Site directed mutations of the active site residue tyrosine 195 of cyclodextrin glyxosyltransferase from bacillus circulans strain 251 affecting activity and product specificity
Source: Bacillus circulans. Organism_taxid: 1397
Chain: A (686 residues) CATH domains: 3.20.20.80 2.60.40.1180 2.60.40.10 2.60.40.10
1ciu
Thermostable cgtase from thermoanaerobacterium thermosulfurigenes em1 at ph 8.0.
Source: Thermoanaerobacterium thermosulfurigenes. Organism_taxid: 33950
Chain: A (683 residues) CATH domains: 3.20.20.80 2.60.40.1180 2.60.40.10 2.60.40.10
1cxe
Complex of cgtase with maltotetraose at room temperature and ph 9.1 based on diffraction data of a crystal soaked with alpha-cyclodextrin
Source: Bacillus circulans. Organism_taxid: 1397. Strain: 251
Chain: A (686 residues) CATH domains: 3.20.20.80 2.60.40.1180 2.60.40.10 2.60.40.10
1cxf
Complex of a (d229n/e257q) double mutant cgtase from bacillus circulans strain 251 with maltotetraose at 120 k and ph 9.1 obtained after soaking the crystal with alpha- cyclodextrin
Source: Bacillus circulans. Organism_taxid: 1397. Strain: 251. Expressed in: bacillus circulans strain db104a.
Chain: A (686 residues) CATH domains: 3.20.20.80 2.60.40.1180 2.60.40.10 2.60.40.10
1cxh
Complex of cgtase with maltotetraose at room temperature and ph 9.6 based on diffraction data of a crystal soaked with maltoheptaose
Source: Bacillus circulans. Organism_taxid: 1397. Strain: 251
Chain: A (686 residues) CATH domains: 3.20.20.80 2.60.40.1180 2.60.40.10 2.60.40.10
1cxi
Wild-type cgtase from bacillus circulans strain 251 at 120 k and ph 7.55
Source: Bacillus circulans. Organism_taxid: 1397. Strain: 251
Chain: A (686 residues) CATH domains: 3.20.20.80 2.60.40.1180 2.60.40.10 2.60.40.10
1cxk
Complex between a maltononaose substrate and bacillus circulans strain 251 cgtase e257q/d229n
Source: Bacillus circulans. Organism_taxid: 1397. Strain: 251. Expressed in: bacillus subtilis. Expression_system_taxid: 1423. Other_details: mutants were constructed in ecoli strain mc1061
Chain: A (686 residues) CATH domains: 3.20.20.80 2.60.40.1180 2.60.40.10 2.60.40.10
1cxl
Complex between a covalent intermediate and bacillus circulans strain 251 cgtase e257q
Source: Bacillus circulans. Organism_taxid: 1397. Strain: 251. Expressed in: bacillus subtilis. Expression_system_taxid: 1423. Other_details: mutants were constructed in ecoli strain mc1061
Chain: A (686 residues) CATH domains: 3.20.20.80 2.60.40.1180 2.60.40.10 2.60.40.10
1cyg
Cyclodextrin glucanotransferase (E.C.2.4.1.19) (cgtase)
Source: Geobacillus stearothermophilus. Organism_taxid: 1422
Chain: A (680 residues) CATH domains: 3.20.20.80 2.60.40.1180 2.60.40.10 2.60.40.10
1d3c
Michaelis complex of bacillus circulans strain 251 cyclodextrin glycosyltransferase with gamma-cyclodextrin
Source: Bacillus circulans. Organism_taxid: 1397. Strain: 251. Cellular_location: extracellular. Expressed in: bacillus subtilis. Expression_system_taxid: 1423.
Chain: A (686 residues) CATH domains: 3.20.20.80 2.60.40.1180 2.60.40.10 2.60.40.10
1d7f
Crystal structure of asparagine 233-replaced cyclodextrin glucanotransferase from alkalophilic bacillus sp. 1011 dete 1.9 a resolution
Source: Bacillus sp.. Organism_taxid: 1410. Strain: 1011. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (686 residues) CATH domains: 3.20.20.80 2.60.40.1180 2.60.40.10 2.60.40.10
1ded
Crystal structure of alkalophilic asparagine 233-replaced cy glucanotransferase complexed with an inhibitor, acarbose, a resolution
Source: Bacillus sp.. Organism_taxid: 1410. Strain: 1011. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (686 residues) CATH domains: 3.20.20.80 2.60.40.1180 2.60.40.10 2.60.40.10
1dtu
Bacillus circulans strain 251 cyclodextrin glycosyltransferase: a mutant y89d/s146p complexed to an hexasaccharide inhibitor
Source: Bacillus circulans. Organism_taxid: 1397. Strain: 251. Cellular_location: extracellular. Expressed in: bacillus subtilis. Expression_system_taxid: 1423.
Chain: A (686 residues) CATH domains: 3.20.20.80 2.60.40.1180 2.60.40.10 2.60.40.10
1eo5
Bacillus circulans strain 251 cyclodextrin glycosyltransferase in complex with maltoheptaose
Source: Bacillus circulans. Organism_taxid: 1397. Strain: 251. Cellular_location: extracellular. Expressed in: bacillus subtilis. Expression_system_taxid: 1423.
Chain: A (686 residues) CATH domains: 3.20.20.80 2.60.40.1180 2.60.40.10 2.60.40.10
1eo7
Bacillus circulans strain 251 cyclodextrin glycosyltransferase in complex with maltohexaose
Source: Bacillus circulans. Organism_taxid: 1397. Strain: 251. Cellular_location: extracellular. Expressed in: bacillus subtilis. Expression_system_taxid: 1423.
Chain: A (686 residues) CATH domains: 3.20.20.80 2.60.40.1180 2.60.40.10 2.60.40.10
1i75
Crystal structure of cyclodextrin glucanotransferase from al bacillus sp.#1011 complexed with 1-deoxynojirimycin
Source: Bacillus sp.. Organism_taxid: 1409. Gene: baccgta. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (686 residues) CATH domains: 3.20.20.80 2.60.40.1180 2.60.40.10 2.60.40.10
1kck
Bacillus circulans strain 251 cyclodextrin glycosyl transferase mutant n193g
Source: Bacillus circulans. Organism_taxid: 1397. Strain: 251. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (686 residues) CATH domains: 3.20.20.80 2.60.40.1180 2.60.40.10 2.60.40.10
1kcl
Bacillus ciruclans strain 251 cyclodextrin glycosyl transferase mutant g179l
Source: Bacillus circulans. Organism_taxid: 1397. Strain: 251. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (686 residues) CATH domains: 3.20.20.80 2.60.40.1180 2.60.40.10 2.60.40.10
1ot1
Bacillus circulans strain 251 cyclodextrin glycosyl transferase mutant d135a
Source: Bacillus circulans. Organism_taxid: 1397. Strain: 251. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (686 residues) CATH domains: 3.20.20.80 2.60.40.1180 2.60.40.10 2.60.40.10
1ot2
Bacillus circulans strain 251 cyclodextrin glycosyl transferase mutant d135n
Source: Bacillus circulans. Organism_taxid: 1397. Strain: 251. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (686 residues) CATH domains: 3.20.20.80 2.60.40.1180 2.60.40.10 2.60.40.10
1pam
Cyclodextrin glucanotransferase
Source: Bacillus sp.. Organism_taxid: 1410. Strain: 1011. Expressed in: escherichia coli. Expression_system_taxid: 562. Other_details: alkalophilic bacillus sp. 1011
Chains: A, B (686 residues) CATH domains: 3.20.20.80 2.60.40.1180 2.60.40.10 2.60.40.10
1pez
Bacillus circulans strain 251 mutant a230v
Source: Bacillus circulans. Organism_taxid: 1397. Strain: 251. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (686 residues) CATH domains: 3.20.20.80 2.60.40.1180 2.60.40.10 2.60.40.10
1pj9
Bacillus circulans strain 251 loop mutant 183-195
Source: Bacillus circulans. Organism_taxid: 1397. Strain: 251. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (686 residues) CATH domains: 3.20.20.80 2.60.40.1180 2.60.40.10 2.60.40.10
1tcm
Cyclodextrin glycosyltransferase w616a mutant from bacillus circulans strain 251
Source: Bacillus circulans. Organism_taxid: 1397. Strain: 251. Expressed in: bacillus circulans. Expression_system_taxid: 1397.
Chains: A, B (686 residues) CATH domains: 3.20.20.80 2.60.40.1180 2.60.40.10 2.60.40.10
1ukq
Crystal structure of cyclodextrin glucanotransferase complex pseudo-maltotetraose derived from acarbose
Source: Bacillus sp.. Organism_taxid: 1410. Strain: 1011. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (686 residues) CATH domains: 3.20.20.80 2.60.40.1180 2.60.40.10 2.60.40.10
1uks
Crystal structure of f183l/f259l mutant cyclodextrin glucanotransferase complexed with a pseudo-maltotetraose de acarbose
Source: Bacillus sp.. Organism_taxid: 1410. Strain: 1011. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (686 residues) CATH domains: 3.20.20.80 2.60.40.1180 2.60.40.10 2.60.40.10
1ukt
Crystal structure of y100l mutant cyclodextrin glucanotransf compexed with an acarbose
Source: Bacillus sp.. Organism_taxid: 1410. Strain: 1011. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (686 residues) CATH domains: 3.20.20.80 2.60.40.1180 2.60.40.10 2.60.40.10
1v3j
Crystal structure of f283l mutant cyclodextrin glycosyltrans
Source: Bacillus sp.. Organism_taxid: 1410. Strain: 1011. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (686 residues) CATH domains: 3.20.20.80 2.60.40.1180 2.60.40.10 2.60.40.10
1v3k
Crystal structure of f283y mutant cyclodextrin glycosyltrans
Source: Bacillus sp.. Organism_taxid: 1410. Strain: 1011. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (686 residues) CATH domains: 3.20.20.80 2.60.40.1180 2.60.40.10 2.60.40.10
1v3l
Crystal structure of f283l mutant cyclodextrin glycosyltrans complexed with a pseudo-tetraose derived from acarbose
Source: Bacillus sp.. Organism_taxid: 1410. Strain: 1011. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (686 residues) CATH domains: 3.20.20.80 2.60.40.1180 2.60.40.10 2.60.40.10
1v3m
Crystal structure of f283y mutant cyclodextrin glycosyltrans complexed with a pseudo-tetraose derived from acarbose
Source: Bacillus sp.. Organism_taxid: 1410. Strain: 1011. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (686 residues) CATH domains: 3.20.20.80 2.60.40.1180 2.60.40.10 2.60.40.10
2cxg
Cyclodextrin glycosyltransferase complexed to the inhibitor acarbose
Source: Bacillus circulans. Organism_taxid: 1397. Strain: 251
Chain: A (686 residues) CATH domains: 3.20.20.80 2.60.40.1180 2.60.40.10 2.60.40.10
2dij
Complex of a y195f mutant cgtase from b. Circulans strain 251 complexed with a maltononaose inhibitor at ph 9.8 obtained after soaking the crystal with acarbose and maltohexaose
Source: Bacillus circulans. Organism_taxid: 1397. Strain: 251. Expressed in: escherichia coli. Expression_system_taxid: 562. Other_details: mutants of bacillus circulans strain 251 cgtase were constructed in e. Coli and afterwards expressed on plasmid pdp66s transformed to b. Subtilis strain db104a
Chain: A (686 residues) CATH domains: 3.20.20.80 2.60.40.1180 2.60.40.10 2.60.40.10
3bmv
Cyclodextrin glycosyl transferase from thermoanerobacterium thermosulfurigenes em1 mutant s77p
Source: Thermoanaerobacterium thermosulfurigen organism_taxid: 33950. Strain: em1. Gene: amya. Expressed in: bacillus subtilis. Expression_system_taxid: 1423.
Chain: A (683 residues) CATH domains: 3.20.20.80 2.60.40.1180 2.60.40.10 2.60.40.10
3bmw
Cyclodextrin glycosyl transferase from thermoanerobacterium thermosulfurigenes em1 mutant s77p complexed with a maltohe inhibitor
Source: Thermoanaerobacterium thermosulfurigen organism_taxid: 33950. Strain: em1. Gene: amya. Expressed in: bacillus subtilis. Expression_system_taxid: 1423.
Chain: A (683 residues) CATH domains: 3.20.20.80 2.60.40.1180 2.60.40.10 2.60.40.10
3cgt
Structure of cyclodextrin glycosyltransferase complexed with its main product beta-cyclodextrin
Source: Bacillus circulans. Organism_taxid: 1397. Strain: 8. Cellular_location: extracellular. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (684 residues) CATH domains: 3.20.20.80 2.60.40.1180 2.60.40.10 2.60.40.10
4cgt
Deletion mutant delta(145-150), f151d of cyclodextrin glycosyltransferase
Source: Bacillus circulans. Organism_taxid: 1397. Strain: 8. Cellular_location: extracellular. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (678 residues) CATH domains: 3.20.20.80 2.60.40.1180 2.60.40.10 2.60.40.10
4jcl
Crystal structure of alpha-cgt from paenibacillus macerans a angstrom resolution
Source: Paenibacillus macerans. Organism_taxid: 44252. Strain: atcc 7069. Gene: cgtm. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (687 residues) CATH domains: 3.20.20.80 2.60.40.1180 2.60.40.10 2.60.40.10
5cgt
Maltotriose complex of preconditioned cyclodextrin glycosyltransferase mutant
Source: Bacillus circulans. Organism_taxid: 1397. Strain: 8. Cellular_location: extracellular. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (684 residues) CATH domains: 3.20.20.80 2.60.40.1180 2.60.40.10 2.60.40.10
6cgt
Hoxa complex of cyclodextrin glycosyltransferase mutant
Source: Bacillus circulans. Organism_taxid: 1397. Strain: 8. Cellular_location: extracellular. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (684 residues) CATH domains: 3.20.20.80 2.60.40.1180 2.60.40.10 2.60.40.10
7cgt
Rameb complex of cyclodextrin glycosyltransferase mutant
Source: Bacillus circulans. Organism_taxid: 1397. Strain: 8. Cellular_location: extracellular. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (684 residues) CATH domains: 3.20.20.80 2.60.40.1180 2.60.40.10 2.60.40.10
8cgt
Structure of cyclodextrin glycosyltransferase complexed with a thio-maltohexaose
Source: Bacillus circulans. Organism_taxid: 1397. Strain: 8. Cellular_location: extracellular. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (684 residues) CATH domains: 3.20.20.80 2.60.40.1180 2.60.40.10 2.60.40.10
9cgt
Structure of cyclodextrin glycosyltransferase complexed with a thio-maltopentaose
Source: Bacillus circulans. Organism_taxid: 1397. Strain: 8. Cellular_location: extracellular. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (684 residues) CATH domains: 3.20.20.80 2.60.40.1180 2.60.40.10 2.60.40.10