_EC 2.3.1.177 3,5-dihydroxybiphenyl synthase. 0 PDB entries  
EC 2.-.-.- Transferases. [17,943 PDB entries]
EC 2.3.-.- Acyltransferases. [1,208 PDB entries]
EC 2.3.1.- Transferring groups other than amino-acyl groups. [998 PDB entries]
EC 2.3.1.177 3,5-dihydroxybiphenyl synthase. [-]    

Reaction: 3 malonyl-CoA + benzoyl-CoA = 4 CoA + 3,5-dihydroxybiphenyl + 4 CO(2).
 


3 × malonyl-CoA
+
benzoyl-CoA
=
4 × CoA
+ 3,5-dihydroxybiphenyl
+
4 × CO(2)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): Biphenyl synthase. Bis.
Comments: A polyketide synthase that is involved in the production of the phytoalexin aucuparin. 2-hydroxybenzoyl-CoA can also act as substrate but it leads to the derailment product 4-hydroxycoumarin (cf. Ec 2.3.1.208). This enzyme uses the same starter substrate as Ec 2.3.1.151.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are no PDB entries in enzyme class E.C.2.3.1.177