_EC 2.2.1.2 Transaldolase. 32 PDB entries  
EC 2.-.-.- Transferases. [17,949 PDB entries]
EC 2.2.-.- Transferring aldehyde or ketone residues. [107 PDB entries]
EC 2.2.1.- Transketolases and transaldolases. [107 PDB entries]
EC 2.2.1.2 Transaldolase. [32 PDB entries]    
1f05

Reaction: Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-erythrose 4-phosphate + D-fructose 6-phosphate.
 


Sedoheptulose 7-phosphate
+
D-glyceraldehyde 3-phosphate
=
D-erythrose 4-phosphate
+
D-fructose 6-phosphate
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): Dihydroxyacetone transferase. Glycerone transferase.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 32 PDB entries in enzyme class E.C.2.2.1.2

  PDB code Protein
1f05
Crystal structure of human transaldolase
Source: Homo sapiens. Human. Organism_taxid: 9606. Cell: myelomonocytic leukemia cells. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (322 residues) CATH domain: 3.20.20.70
1i2n
Crystal structure of escherichia coli transaldolase b mutant n35a
Source: Escherichia coli. Organism_taxid: 562. Gene: talb. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (316 residues) CATH domain: 3.20.20.70
1i2o
Crystal structure of escherichia coli transaldolase b mutant e96a
Source: Escherichia coli. Organism_taxid: 562. Gene: talb. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (316 residues) CATH domain: 3.20.20.70
1i2p
Crystal structure of escherichia coli transaldolase b mutant d17a
Source: Escherichia coli. Organism_taxid: 562. Gene: talb. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (316 residues) CATH domain: 3.20.20.70
1i2q
Crystal structure of escherichia coli transaldolase b mutant t156a
Source: Escherichia coli. Organism_taxid: 562. Gene: talb. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (316 residues) CATH domain: 3.20.20.70
1i2r
Crystal structure of escherichia coli transaldolase b mutant s176a
Source: Escherichia coli. Organism_taxid: 562. Gene: talb. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (316 residues) CATH domain: 3.20.20.70
1onr
Structure of transaldolase b
Source: Escherichia coli. Organism_taxid: 562. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (316 residues) CATH domain: 3.20.20.70
1ucw
Complex of transaldolase with the reduced schiff-base intermediate
Source: Escherichia coli. Organism_taxid: 562. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (316 residues) CATH domain: 3.20.20.70
1vpx
Crystal structure of transaldolase (ec 2.2.1.2) (tm0295) fro thermotoga maritima at 2.40 a resolution
Source: Thermotoga maritima. Organism_taxid: 2336. Gene: tm0295. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D, E, F, G, H, I, J, K, L, M, N, O, P, Q, R, S, T (207 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group GOL is 60.00% similar to enzyme reactant D-glyceraldehyde
1wx0
Crystal structure of transaldolase from thermus thermophilus hb8
Source: Thermus thermophilus hb8. Organism_taxid: 300852. Strain: hb8 / atcc 27634 / dsm 579. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B, C, D, E, F, G, H, I, J (211 residues) CATH domain: 3.20.20.70
2cwn
Crystal structure of mouse transaldolase
Source: Mus musculus. House mouse. Organism_taxid: 10090. Other_details: cell free protein synthesis
Chains: A, B (321 residues) CATH domain: 3.20.20.70
2e1d
Crystal structure of mouse transaldolase
Source: Mus musculus. House mouse. Organism_taxid: 10090. Other_details: cell-free protein synthesis
Chains: A, B (321 residues) CATH domain: 3.20.20.70
3clm
Crystal structure of transaldolase (yp_208650.1) from neisse gonorrhoeae fa 1090 at 1.14 a resolution
Source: Neisseria gonorrhoeae. Organism_taxid: 242231. Strain: fa 1090. Atcc: 700825. Gene: yp_208650.1, tal, ngo1610. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (352 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group EDO is 40.00% similar to enzyme reactant D-glyceraldehyde
3cq0
Crystal structure of tal2_yeast
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (325 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group GOL is 60.00% similar to enzyme reactant D-glyceraldehyde
3cwn
Escherichia coli transaldolase b mutant f178y
Source: Escherichia coli. Strain k12. Organism_taxid: 562. Strain: w3110. Gene: talb, yaak. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (316 residues) CATH domain: 3.20.20.70
3hjz
The structure of an aldolase from prochlorococcus marinus
Source: Prochlorococcus marinus str. Mit 9312. Organism_taxid: 74546. Strain: mit 9132. Gene: pmt9312_0519, tal, transaldose b. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (333 residues) CATH domain: 3.20.20.70
Bound ligands:   Het Group EDO is 40.00% similar to enzyme reactant D-glyceraldehyde
  Het Group PEG is 43.75% similar to enzyme product D-fructose
3igx
1.85 angstrom resolution crystal structure of transaldolase from francisella tularensis.
Source: Francisella tularensis subsp. Tularens organism_taxid: 177416. Strain: tularensis schu s4. Gene: ftt1093c, ftt_1093c, tala. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (322 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group PO4 is 50.00% similar to enzyme reactant D-glyceraldehyde
3kof
Crystal structure of the double mutant f178y/r181e of e.Coli transaldolase b
Source: Escherichia coli k-12. Organism_taxid: 83333. Strain: w3110 / k12 / dsm 5911. Atcc: 27325. Gene: talb, yaak, b0008, jw0007. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (316 residues) CATH domain: 3.20.20.70
3m16
Structure of a transaldolase from oleispira antarctica
Source: Oleispira antarctica. Organism_taxid: 188908. Gene: olei02190. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (326 residues) CATH domain: 3.20.20.70
3r5e
Transaldolase from corynebacterium glutamicum
Source: Corynebacterium glutamicum. Organism_taxid: 1718. Gene: cg1776, cgl1575, tal. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (360 residues) CATH domain: 3.20.20.70
3r8r
Transaldolase from bacillus subtilis
Source: Bacillus subtilis. Organism_taxid: 1423. Gene: bsu37110, tal, ywjh. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D, E, F, G, H, I, J, V, K, L, M, N, W, P, R, T, U (212 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group GOL is 60.00% similar to enzyme reactant D-glyceraldehyde
3s0c
Transaldolase wt of thermoplasma acidophilum
Source: Thermoplasma acidophilum. Organism_taxid: 273075. Strain: atcc 25905 / dsm 1728 / jcm 9062 / nbrc 15155 / amr gene: ta0616, tal. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D, E (218 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group GOL is 60.00% similar to enzyme reactant D-glyceraldehyde
3s1u
Transaldolase from thermoplasma acidophilum in complex with erythrose 4-phosphate
Source: Thermoplasma acidophilum. Organism_taxid: 273075. Strain: atcc 25905 / dsm 1728 / jcm 9062 / nbrc 15155 / amr gene: ta0616, tal. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D, E (218 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group E4P corresponds to enzyme product D-erythrose
3s1v
Transaldolase from thermoplasma acidophilum in complex with 6-phosphate schiff-base intermediate
Source: Thermoplasma acidophilum. Organism_taxid: 273075. Strain: atcc 25905 / dsm 1728 / jcm 9062 / nbrc 15155 / amr gene: ta0616, tal. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D, E (223 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group F6R is 93.75% similar to enzyme product D-fructose
3s1w
Transaldolase variant lys86ala from thermoplasma acidophilum complex with glycerol and citrate
Source: Thermoplasma acidophilum. Organism_taxid: 273075. Strain: atcc 25905 / dsm 1728 / jcm 9062 / nbrc 15155 / amr gene: ta0616, tal. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D, E (223 residues) CATH domain: 3.20.20.70
Bound ligands:   Het Group GOL is 60.00% similar to enzyme reactant D-glyceraldehyde
  Het Group FLC is 45.00% similar to enzyme product D-fructose
3s1x
Transaldolase from thermoplasma acidophilum in complex with sedoheptulose 7-phosphate schiff-base intermediate
Source: Thermoplasma acidophilum. Organism_taxid: 273075. Strain: atcc 25905 / dsm 1728 / jcm 9062 / nbrc 15155 / amr gene: ta0616, tal. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D, E (223 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group I22 is 94.44% similar to enzyme reactant Sedoheptulose
3te9
1.8 angstrom resolution crystal structure of k135m mutant of transaldolase b (tala) from francisella tularensis in compl fructose 6-phosphate
Source: Francisella tularensis subsp. Tularens organism_taxid: 119856. Strain: schu s4. Gene: ftt_1093c, tala. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chains: A, B (310 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group F6R corresponds to enzyme product D-fructose
3tk7
2.0 angstrom resolution crystal structure of transaldolase b from francisella tularensis in covalent complex with fructo phosphate
Source: Francisella tularensis subsp. Tularens organism_taxid: 119856. Strain: schu s4. Gene: ftt_1093c, tala. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chains: A, B (320 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group F6R is 93.75% similar to enzyme product D-fructose
3tkf
1.5 angstrom resolution crystal structure of k135m mutant of transaldolase b (tala) from francisella tularensis in compl sedoheptulose 7-phosphate.
Source: Francisella tularensis subsp. Tularens organism_taxid: 119856. Strain: schu s4. Gene: ftt_1093c, tala. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chains: A, B (310 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group I22 corresponds to enzyme reactant Sedoheptulose
3tno
1.65 angstrom resolution crystal structure of transaldolase from francisella tularensis in covalent complex with sedohe phosphate
Source: Francisella tularensis subsp. Tularens organism_taxid: 177416. Strain: schu s4. Gene: ftt_1093c, tala. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chains: A, B (320 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group I22 is 94.44% similar to enzyme reactant Sedoheptulose
3upb
1.5 angstrom resolution crystal structure of transaldolase f francisella tularensis in covalent complex with arabinose-5
Source: Francisella tularensis subsp. Tularens organism_taxid: 119856. Strain: schu s4. Gene: ftt_1093c, tala. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chains: A, B (311 residues) CATH domain: 3.20.20.70
Bound ligand:   Het Group A5P is 92.31% similar to enzyme product D-erythrose
4e0c
1.8 angstrom resolution crystal structure of transaldolase f francisella tularensis (phosphate-free)
Source: Francisella tularensis subsp. Tularens organism_taxid: 177416. Strain: schu s4 / schu 4. Gene: ftt_1093c, tala. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (313 residues) CATH domain: 3.20.20.70