_EC Methanol--corrinoid protein Co-methyltransferase. 1 PDB entries  
EC 2.-.-.- Transferases. [17,949 PDB entries]
EC 2.1.-.- Transferring one-carbon groups. [1,711 PDB entries]
EC 2.1.1.- Methyltransferases. [1,381 PDB entries]
EC Methanol--corrinoid protein Co-methyltransferase. [1 PDB entries]    

Reaction: Methanol + a [Co(I) methanol-specific corrinoid protein] = a [methyl- Co(III) methanol-specific corrinoid protein] + H(2)O.

+ [Co(I) methanol-specific corrinoid protein]
= [methyl- Co(III) methanol-specific corrinoid protein]
+ H(2)O
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): Methanol--5-hydroxybenzimidazolylcobamide Co-methyltransferase.
Comments: The enzyme, which catalyzes the transfer of methyl groups from methanol to a methanol-specific corrinoid protein (MtaC), is involved in methanogenesis from methanol. Methylation of the corrinoid protein requires the central cobalt to be in the Co(I) state. During methylation the cobalt is oxidized to the Co(III) state. Free cob(I)alamin can substitute for the corrinoid protein in vitro. Inactivated by oxygen and other oxidizing agents, and reactivated by catalytic amounts of Atp and hydrogen.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 1 PDB entries in enzyme class E.C.

  PDB code Protein
Crystal structure of methanol:cobalamin methyltransferase co mtabc from methanosarcina barkeri
Source: Methanosarcina barkeri. Organism_taxid: 2208. Strain: fuaro (dsm 804). Strain: fuaro (dsm 804)
Chains: A, C, E, G, I, K, M, O (459 residues) CATH domain: Unassigned
Bound ligand:   Het Group B13 is 82.00% similar to enzyme reactant 5-hydroxybenzimidazolylcobamide