_EC 2.1.1.68 Caffeate O-methyltransferase. 4 PDB entries  
EC 2.-.-.- Transferases. [17,949 PDB entries]
EC 2.1.-.- Transferring one-carbon groups. [1,711 PDB entries]
EC 2.1.1.- Methyltransferases. [1,381 PDB entries]
EC 2.1.1.68 Caffeate O-methyltransferase. [4 PDB entries]    
1kyw

Reaction: S-adenosyl-L-methionine + 3,4-dihydroxy-trans-cinnamate = S-adenosyl-L- homocysteine + 3-methoxy-4-hydroxy-trans-cinnamate.
 


S-adenosyl-L-methionine
+
3,4-dihydroxy-trans-cinnamate
=
S-adenosyl-L- homocysteine
+
3-methoxy-4-hydroxy-trans-cinnamate
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Comments: 3,4-dihydroxybenzaldehyde and catechol can act as acceptor, more slowly.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 4 PDB entries in enzyme class E.C.2.1.1.68

  PDB code Protein
1kyw
Crystal structure analysis of caffeic acid/5-hydroxyferulic acid 3/5-o-methyltransferase in complex with 5- hydroxyconiferaldehyde
Source: Medicago sativa. Organism_taxid: 3879. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, C, F (350 residues) CATH domains: 1.10.10.10 3.40.50.150
Bound ligands:   Het Group SAH corresponds to enzyme product S-adenosylhomocysteine
  Het Group HFL is 93.00% similar to enzyme product ferulate
1kyz
Crystal structure analysis of caffeic acid/5-hydroxyferulic acid 3/5-o-methyltransferase ferulic acid complex
Source: Medicago sativa. Organism_taxid: 3879. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, C, E (350 residues) CATH domains: 1.10.10.10 3.40.50.150
Bound ligands:   Het Group SAH corresponds to enzyme product S-adenosylhomocysteine
  Het Group FER corresponds to enzyme product ferulate
4pgg
Caffeic acid o-methyltransferase from sorghum bicolor
Source: Sorghum bicolor. Sorghum. Organism_taxid: 4558. Gene: sb07g003860, sorbidraft_07g003860. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (360 residues) CATH domains: 1.10.10.10 3.40.50.150
4pgh
Caffeic acid o-methyltransferase from sorghum bicolor
Source: Sorghum bicolor. Sorghum. Organism_taxid: 4558. Gene: sb07g003860, sorbidraft_07g003860. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (354 residues) CATH domains: 1.10.10.10 3.40.50.150
Bound ligand:   Het Group SAM corresponds to enzyme reactant S-adenosyl-L-methionine