_EC 2.1.1.56 mRNA (guanine-N(7)-)-methyltransferase. 110 PDB entries  
EC 2.-.-.- Transferases. [17,943 PDB entries]
EC 2.1.-.- Transferring one-carbon groups. [1,710 PDB entries]
EC 2.1.1.- Methyltransferases. [1,380 PDB entries]
EC 2.1.1.56 mRNA (guanine-N(7)-)-methyltransferase. [110 PDB entries]    
1ej6

Reaction: S-adenosyl-L-methionine + G(5')pppR-RNA = S-adenosyl-L-homocysteine + m(7)G(5')pppR-RNA.
 


S-adenosyl-L-methionine
+
G(5')pppR-RNA
=
S-adenosyl-L-homocysteine
+
m(7)G(5')pppR-RNA
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): Guanine-7-methyltransferase. Messenger ribonucleate guanine 7-methyltransferase. Messenger Rna guanine 7-methyltransferase.
Comments: Adds an N(7)-methylguanine cap to mRNA. The nucleoside next to the terminal guanosine may be either guanosine or adenosine.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 110 PDB entries in enzyme class E.C.2.1.1.56

  PDB code Protein
1ej6
Reovirus core
Source: Reovirus sp.. Organism_taxid: 10891. Strain: reassortant f18. Strain: reassortant f18
Chain: A (1284 residues) CATH domains: 3.90.1810.10 3.55.60.10 3.40.50.10760 3.40.50.150 2.60.40.10
1ic3
Theoretical model of s.Cerevisiae cap 0 (mrna:guanine-n7) methyltransferase
Source: Saccharomyces cerevisiae. Yeast
Chain: A (258 residues)
1l9k
Dengue methyltransferase
Source: Dengue virus. Organism_taxid: 11060. Strain: 2. Gene: ns5 new guinea c. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (261 residues) CATH domain: 3.40.50.150
Bound ligand:   Het Group SAH corresponds to enzyme product S-adenosylhomocysteine
1n6g
The structure of immature dengue-2 prm particles
Source: Dengue virus 2 puerto rico/pr159- s1/1969. Organism_taxid: 11066. Strain: pr159/s1
Chains: A, B, C (395 residues)
1na4
The structure of immature yellow fever virus particle
Source: Yellow fever virus. Organism_taxid: 11089
Chains: A, B, C ( residues)
1oan
Crystal structure of the dengue 2 virus envelope protein
Source: Dengue virus type 2. Organism_taxid: 11060. Strain: strain pr159/s1. Expressed in: drosophila melanogaster. Expression_system_taxid: 7227. Expression_system_cell_line: schneider 2.
Chains: A, B (394 residues) CATH domains: 2.60.98.10 3.30.67.10 3.30.387.10 2.60.40.350
1ok8
Crystal structure of the dengue 2 virus envelope glycoprotein in the postfusion conformation
Source: Dengue virus type 2. Organism_taxid: 11060. Strain: pr159/s1. Expressed in: drosophila melanogaster. Expression_system_taxid: 7227. Expression_system_cell_line: schneider 2.
Chain: A (380 residues) CATH domains: 2.60.98.10 3.30.67.10 3.30.387.10 2.60.40.350
1oke
Crystal structure of the dengue 2 virus envelope protein in complex with n-octyl-beta-d-glucoside
Source: Dengue virus type 2. Organism_taxid: 11060. Strain: pr159/s1. Expressed in: drosophila melanogaster. Expression_system_taxid: 7227. Expression_system_cell_line: schneider 2.
Chains: A, B (394 residues) CATH domains: 2.60.98.10 3.30.67.10 3.30.387.10 2.60.40.350
1p58
Complex organization of dengue virus membrane proteins as re 9.5 angstrom cryo-em reconstruction
Source: Dengue virus 2 puerto rico/pr159-s1/19 organism_taxid: 11066. Strain: pr159/s1. Strain: pr159/s1
Chains: A, B, C (490 residues)
1r6a
Structure of the dengue virus 2'o methyltransferase in complex with s-adenosyl homocysteine and ribavirin 5' triphosphate
Source: Dengue virus 2 puerto rico/pr159- s1/1969. Organism_taxid: 11066. Strain: pr159-s1. Gene: ns5. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (262 residues) CATH domain: 3.40.50.150
Bound ligand:   Het Group SAH corresponds to enzyme product S-adenosylhomocysteine
1r6r
Solution structure of dengue virus capsid protein reveals a new fold
Source: Dengue virus 2 puerto rico/pr159- s1/1969. Organism_taxid: 11066. Strain: pr-159-s1. Gene: capsid gene. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (80 residues) CATH domain: Unassigned
1ri1
Structure and mechanism of mRNA cap (guanine n-7) methyltransferase
Source: Encephalitozoon cuniculi. Organism_taxid: 6035. Gene: ecu10_0380. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (252 residues) CATH domain: 3.40.50.150
Bound ligands:   Het Group GTG is 47.00% similar to enzyme reactant G(5')pppR-RNA
  Het Group SAH corresponds to enzyme product S-adenosylhomocysteine
1ri2
Structure and mechanism of mRNA cap (guanine n-7) methyltransferase
Source: Encephalitozoon cuniculi. Organism_taxid: 6035. Gene: ecu10_0380. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (252 residues) CATH domain: 3.40.50.150
Bound ligand:   Het Group GTG is 47.00% similar to enzyme reactant G(5')pppR-RNA
1ri3
Structure and mechanism of mRNA cap (guanine n-7) methyltransferase
Source: Encephalitozoon cuniculi. Organism_taxid: 6035. Gene: ecu10_0380. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (252 residues) CATH domain: 3.40.50.150
Bound ligand:   Het Group SAH corresponds to enzyme product S-adenosylhomocysteine
1ri4
Structure and mechanism of mRNA cap (guanine n-7) methyltransferase
Source: Encephalitozoon cuniculi. Organism_taxid: 6035. Gene: ecu10_0380. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (252 residues) CATH domain: 3.40.50.150
Bound ligand:   Het Group SAM corresponds to enzyme reactant S-adenosyl-L-methionine
1ri5
Structure and mechanism of mRNA cap (guanine n-7) methyltransferase
Source: Encephalitozoon cuniculi. Organism_taxid: 6035. Gene: ecu10_0380. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (252 residues) CATH domain: 3.40.50.150
1sfk
Core (c) protein from west nile virus, subtype kunjin
Source: Kunjin virus. Organism_taxid: 11078. Strain: mrm61c. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B, C, D, E, F, G, H (73 residues)
1svb
Envelope glycoprotein from tick-borne encephalitis virus
Source: Tick-borne encephalitis virus. Organism_taxid: 11084
Chain: A (395 residues) CATH domains: 2.60.98.10 3.30.67.10 3.30.387.10 2.60.40.350
1thd
Complex organization of dengue virus e protein as revealed by 9.5 angstrom cryo-em reconstruction
Source: Dengue virus 2 puerto rico/pr159- s1/1969. Organism_taxid: 11066. Strain: pr159-s1
Chains: A, B, C (390 residues)
1uzg
Crystal structure of the dengue type 3 virus envelope protein
Source: Dengue virus type 3. Organism_taxid: 11069. Cell_line: drosophila schneider 2. Expressed in: drosophila melanogaster. Expression_system_taxid: 7227. Expression_system_cell_line: schneider 2.
Chains: A, B (392 residues) CATH domains: 2.60.98.10 3.30.67.10 3.30.387.10 2.60.40.350
1yks
Crystal structure of yellow fever virus ns3 helicase
Source: Yellow fever virus. Organism_taxid: 11089. Strain: strain pasteur 17d-204. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (431 residues) CATH domains: Unassigned 3.40.50.300
1ymf
Crystal structure of yellow fever virus ns3 helicase complexed with adp
Source: Yellow fever virus. Organism_taxid: 11089. Strain: strain pasteur 17d-204. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (431 residues) CATH domains: Unassigned 3.40.50.300
Bound ligand:   Het Group ADP is 51.00% similar to enzyme product S-adenosylhomocysteine
1z3c
Encephalitozooan cuniculi mRNA cap (guanine-n7) methyltransferasein complexed with azoadomet
Source: Encephalitozoon cuniculi. Organism_taxid: 6035. Gene: ecu10_0380. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (252 residues) CATH domain: 3.40.50.150
Bound ligand:   Het Group SA8 is 51.00% similar to enzyme product S-adenosylhomocysteine
1z66
Nmr solution structure of domain iii of e-protein of tick- borne langat flavivirus (no rdc restraints)
Source: Langat virus. Organism_taxid: 11085. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (93 residues) CATH domain: 2.60.40.350
2cse
Features of reovirus outer-capsid protein mu1 revealed by electron and image reconstruction of the virion at 7.0-a resolution
Source: Mammalian orthoreovirus 1. Organism_taxid: 10884. Strain: lang. Mammalian orthoreovirus 3. Organism_taxid: 10886. Strain: dearing. Strain: lang
Chain: U (1284 residues)
2fp7
West nile virus ns2b/ns3protease in complex with bz-nle-lys-
Source: West nile virus. Organism_taxid: 11082. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes
Chains: A, B (40 residues) CATH domain: Unassigned
2gg1
Nmr solution structure of domain iii of the e-protein of tick-borne langat flavivirus (includes rdc restraints)
Source: Langat virus. Organism_taxid: 11085. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (93 residues) CATH domain: 2.60.40.350
2ggv
Crystal structure of the west nile virus ns2b-ns3 protease, his51ala mutant
Source: West nile virus. Organism_taxid: 11082. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (44 residues) CATH domain: Unassigned
2h0p
Nmr structure of the dengue-4 virus envelope protein domain iii
Source: Dengue virus 4. Organism_taxid: 11070. Strain: 4. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (112 residues) CATH domain: 2.60.40.350
2hcn
Crystal structure of RNA dependent RNA polymerase domain fro nile virus
Source: Kunjin virus. Organism_taxid: 11077. Strain: kunjin. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (486 residues) CATH domains: Unassigned Unassigned Unassigned
2hcs
Crystal structure of RNA dependant RNA polymerase domain of virus
Source: Kunjin virus. Organism_taxid: 11077. Strain: kunjin. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (487 residues) CATH domains: Unassigned Unassigned Unassigned
2hfz
Crystal structure of RNA dependent RNA polymerase domain from west nile virus
Source: Kunjin virus. Organism_taxid: 11077. Strain: kunjin. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (608 residues) CATH domains: Unassigned Unassigned Unassigned Unassigned
2hv9
Encephalitozoon cuniculi mRNA cap (guanine-n7) methyltransfe complex with sinefungin
Source: Encephalitozoon cuniculi. Organism_taxid: 6035. Gene: ecm1. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (248 residues) CATH domain: 3.40.50.150
Bound ligand:   Het Group SFG is 51.43% similar to enzyme product S-adenosylhomocysteine
2ijo
Crystal structure of the west nile virus ns2b-ns3 protease complexed with bovine pancreatic trypsin inhibitor
Source: West nile virus. Organism_taxid: 11082. Expressed in: escherichia coli. Expression_system_taxid: 562. Bos taurus. Cattle. Organism_taxid: 9913
Chains: A, B (41 residues) CATH domain: Unassigned
2jlq
Dengue virus 4 ns3 helicase structure, apo enzyme.
Source: Dengue virus 4. Organism_taxid: 408688. Strain: thailand/0348/1991. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (451 residues) CATH domains: Unassigned 3.40.50.300
2jlr
Dengue virus 4 ns3 helicase in complex with amppnp
Source: Dengue virus 4. Organism_taxid: 408688. Strain: thailand/0348/1991. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (439 residues) CATH domains: Unassigned 3.40.50.300
Bound ligand:   Het Group ANP is 46.15% similar to enzyme product S-adenosylhomocysteine
2jls
Dengue virus 4 ns3 helicase in complex with adp
Source: Dengue virus 4. Organism_taxid: 408688. Strain: thailand/0348/1991. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (443 residues) CATH domains: Unassigned 3.40.50.300
Bound ligand:   Het Group ADP is 51.43% similar to enzyme product S-adenosylhomocysteine
2jlu
Dengue virus 4 ns3 helicase in complex with ssrna
Source: Dengue virus 4. Organism_taxid: 408688. Strain: thailand/0348/1991. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes
Chains: A, B (451 residues) CATH domains: Unassigned 3.40.50.300
2jlv
Dengue virus 4 ns3 helicase in complex with ssrna and amppnp
Source: Dengue virus 4. Organism_taxid: 408688. Strain: thailand/0348/1991. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes
Chains: A, B (451 residues) CATH domains: Unassigned 3.40.50.300
Bound ligand:   Het Group ANP is 46.15% similar to enzyme product S-adenosylhomocysteine
2jlw
Dengue virus 4 ns3 helicase in complex with ssrna2
Source: Dengue virus 4. Organism_taxid: 408688. Strain: thailand/0348/1991. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes
Chains: A, B (450 residues) CATH domains: Unassigned 3.40.50.300
2jlx
Dengue virus 4 ns3 helicase in complex with ssrna and adp- vanadate
Source: Dengue virus 4. Organism_taxid: 408688. Strain: thailand/0348/1991. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes
Chains: A, B (451 residues) CATH domains: Unassigned 3.40.50.300
Bound ligand:   Het Group ADP is 51.43% similar to enzyme product S-adenosylhomocysteine
2jly
Dengue virus 4 ns3 helicase in complex with ssrna and adp- phosphate
Source: Dengue virus 4. Organism_taxid: 408688. Strain: thailand/0348/1991. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes
Chains: A, B (451 residues) CATH domains: Unassigned 3.40.50.300
Bound ligand:   Het Group ADP is 51.43% similar to enzyme product S-adenosylhomocysteine
2jlz
Dengue virus 4 ns3 helicase in complex with ssrna and adp
Source: Dengue virus 4. Organism_taxid: 408688. Strain: thailand/0348/1991. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes
Chains: A, B (451 residues) CATH domains: Unassigned 3.40.50.300
Bound ligand:   Het Group ADP is 51.43% similar to enzyme product S-adenosylhomocysteine
2jqm
Yellow fever envelope protein domain iii nmr structure (s288-k398)
Source: Yellow fever virus. Strain: asibi. Expressed in: escherichia coli. Other_details: the n-terminal his tag of this vector was removed
Chain: A (112 residues) CATH domain: 2.60.40.350
2jv6
Yf ed3 protein nmr structure
Source: Yellow fever virus. Yfv. Organism_taxid: 11089. Strain: asibi 17d. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (112 residues) CATH domain: 2.60.40.350
2m9p
Nmr structure of an inhibitor bound dengue ns3 protease
Source: Dengue virus 2. Organism_taxid: 413041. Strain: thailand/0168/1979. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes
Chain: A (240 residues)
2m9q
Nmr structure of an inhibitor bound dengue ns3 protease
Source: Dengue virus 2. Organism_taxid: 413041. Strain: thailand/0168/1979. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes
Chain: A (240 residues)
2p1d
Crystal structure of dengue methyltransferase in complex wit s-adenosyl-l-homocysteine
Source: Dengue virus 2. Organism_taxid: 11060. Strain: type 2 new guinea. Gene: nsp5. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (259 residues) CATH domain: 3.40.50.150
Bound ligand:   Het Group SAH corresponds to enzyme product S-adenosylhomocysteine
2p5p
Crystal structure analysis of the west nile virus envelope (e) protein domain iii
Source: West nile virus. Organism_taxid: 11082. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chains: A, B, C (101 residues) CATH domain: 2.60.40.350
2px2
Crystal structure of the murray valley encephalitis virus ns5 2'-o methyltransferase domain in complex with sah (monoclinic form 1)
Source: Murray valley encephalitis virus (strain mve-1-51). Organism_taxid: 301478. Strain: mve-1-51, mvev. Gene: ns5. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (255 residues) CATH domain: 3.40.50.150
Bound ligand:   Het Group SAH corresponds to enzyme product S-adenosylhomocysteine
2px4
Crystal structure of the murray valley encephalitis virus ns methyltransferase domain in complex with sah (monoclinic fo
Source: Murray valley encephalitis virus (stra 51). Organism_taxid: 301478. Strain: mve-1-51, mvev. Gene: ns5. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (261 residues) CATH domain: 3.40.50.150
Bound ligand:   Het Group SAH corresponds to enzyme product S-adenosylhomocysteine
2px5
Crystal structure of the murray valley encephalitis virus ns methyltransferase domain in complex with sah (orthorhombic form)
Source: Murray valley encephalitis virus (stra 51). Organism_taxid: 301478. Strain: mve-1-51, mvev. Gene: ns5. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (265 residues) CATH domain: 3.40.50.150
Bound ligand:   Het Group SAH corresponds to enzyme product S-adenosylhomocysteine
2px8
Crystal structure of the murray valley encephalitis virus ns methyltransferase domain in complex with sah and 7m-gtp
Source: Murray valley encephalitis virus (stra 51). Organism_taxid: 301478. Strain: mve-1-51, mvev. Gene: ns5. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (264 residues) CATH domain: 3.40.50.150
Bound ligands:   Het Group SAH corresponds to enzyme product S-adenosylhomocysteine
  Het Group MGT is 48.53% similar to enzyme product m(7)G(5')pppR-RNA
2pxa
Crystal structure of the murray valley encephalitis virus ns methyltransferase domain in complex with sah and gtpg
Source: Murray valley encephalitis virus (stra 51). Organism_taxid: 301478. Strain: mve-1-51, mvev. Gene: ns5. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (262 residues) CATH domain: 3.40.50.150
Bound ligands:   Het Group GTP is 47.76% similar to enzyme reactant G(5')pppR-RNA
  Het Group SAH corresponds to enzyme product S-adenosylhomocysteine
2pxc
Crystal structure of the murray valley encephalitis virus ns methyltransferase domain in complex with sam and gtpa
Source: Murray valley encephalitis virus (stra 51). Organism_taxid: 301478. Strain: mve-1-51, mvev. Gene: ns5. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (263 residues) CATH domain: 3.40.50.150
Bound ligands:   Het Group SAM corresponds to enzyme reactant S-adenosyl-L-methionine
  Het Group G3A is 51.95% similar to enzyme reactant G(5')pppR-RNA
2qeq
Crystal structure of kunjin virus ns3 helicase
Source: Kunjin virus (strain mrm61c). Organism_taxid: 11078. Strain: mrm61c. Expressed in: escherichia coli. Expression_system_taxid: 562. Other_details: part of genome polyprotein
Chains: A, B (415 residues) CATH domains: Unassigned 3.40.50.300
2qy2
Characterization of a trifunctional mimivirus mRNA capping enzyme and crystal structure of the RNA triphosphatase domainm.
Source: Mimivirus. Organism_taxid: 315393. Gene: refseq yp_142736. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (224 residues) CATH domain: 3.20.100.10
2qze
Monoclinic mimivirus capping enzyme triphosphatase.
Source: Mimivirus. Organism_taxid: 315393. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (220 residues) CATH domain: 3.20.100.10
2r29
Neutralization of dengue virus by a serotype cross-reactive antibody elucidated by cryoelectron microscopy and x-ray crystallography
Source: Dengue virus 2 thailand/16681/84. Organism_taxid: 31634. Strain: 16681. Gene: e protein. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Mus musculus. House mouse. Organism_taxid: 10090.
Chain: A (97 residues) CATH domain: 2.60.40.350
2v8o
Structure of the murray valley encephalitis virus RNA helicase to 1.9a resolution
Source: Murray valley encephalitis virus. Organism_taxid: 11079. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_variant: de3. Expression_system_cell_line: plyss
Chain: A (429 residues) CATH domains: Unassigned 3.40.50.300
2vdw
Guanosine n7 methyl-transferase sub-complex (d1-d12) of the vaccinia virus mRNA capping enzyme
Source: Vaccinia virus. Organism_taxid: 10245. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: plyss. Expression_system_variant: plyss
Chains: A, C, E, G (296 residues) CATH domain: 3.40.50.150
Bound ligand:   Het Group SAH is 45.00% similar to enzyme reactant GTP
2whx
A second conformation of the ns3 protease-helicase from dengue virus
Source: Dengue virus 4. Organism_taxid: 11070. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_taxid: 562
Chains: A, C (582 residues) CATH domains: Unassigned Unassigned 3.40.50.300
Bound ligand:   Het Group ADP is 51.43% similar to enzyme product S-adenosylhomocysteine
2wv9
Crystal structure of the ns3 protease-helicase from murray valley encephalitis virus
Source: Murray valley encephalitis virus. Organism_taxid: 301478. Strain: mve-1-51. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (601 residues) CATH domains: Unassigned Unassigned 3.40.50.300
2wzq
Insertion mutant e173gp174 of the ns3 protease-helicase from dengue virus
Source: Dengue virus. Organism_taxid: 12637. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_taxid: 562
Chains: A, C (581 residues) CATH domains: Unassigned Unassigned 3.40.50.300
2yol
West nile virus ns2b-ns3 protease in complex with 3,4- dichlorophenylacetyl-lys-lys-gcma
Source: West nile virus. Organism_taxid: 11082. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: gold.
Chain: A (212 residues) CATH domain: 2.40.10.120
2z83
Crystal structure of catalytic domain of japanese encephalitis virus ns3 helicase/nucleoside triphosphatase at a resolution 1.8
Source: Japanese encephalitis virus. Organism_taxid: 11072. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (426 residues) CATH domains: Unassigned 3.40.50.300
3bgv
Crystal structure of mRNA cap guanine-n7 methyltransferase in complex with sah
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: rnmt, kiaa0398. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (269 residues) CATH domain: 3.40.50.150
Bound ligand:   Het Group SAH corresponds to enzyme product S-adenosylhomocysteine
3bgy
Triclinic structure of mimivirus capping enzyme triphosphatase at 1.65 a
Source: Acanthamoeba polyphaga mimivirus. Organism_taxid: 212035. Gene: yp_142736. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (226 residues) CATH domain: 3.20.100.10
3e90
West nile vi rus ns2b-ns3protease in complexed with inhibitor naph-kkr-h
Source: West nile virus. Wnv. Organism_taxid: 11082. Strain: wnv ny99-4132. Gene: ns2b-ns3protease. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (47 residues) CATH domain: Unassigned
3epp
Crystal structure of mRNA cap guanine-n7 methyltransferase ( complex with sinefungin
Source: Homo sapiens. Organism_taxid: 9606. Gene: rnmt, kiaa0398. Expressed in: escherichia coli.
Chains: A, B (265 residues) CATH domain: 3.40.50.150
Bound ligand:   Het Group SFG is 51.43% similar to enzyme product S-adenosylhomocysteine
3eva
Crystal structure of yellow fever virus methyltransferase co with s-adenosyl-l-homocysteine
Source: Yellow fever virus. Organism_taxid: 11090. Strain: 17d. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (261 residues) CATH domain: 3.40.50.150
Bound ligand:   Het Group SAH corresponds to enzyme product S-adenosylhomocysteine
3evb
Crystal structure of yellow fever virus methyltransferase co with s-adenosyl-l-homocysteine
Source: Yellow fever virus. Organism_taxid: 11090. Strain: 17d. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (261 residues) CATH domain: 3.40.50.150
Bound ligand:   Het Group SAH corresponds to enzyme product S-adenosylhomocysteine
3evc
Crystal structure of gtp complex of yellow fever virus methyltransferase and s-adenosyl-l-homocysteine
Source: Yellow fever virus. Organism_taxid: 11090. Strain: 17d. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (261 residues) CATH domain: 3.40.50.150
Bound ligands:   Het Group GTP is 41.79% similar to enzyme reactant G(5')pppR-RNA
  Het Group SAH corresponds to enzyme product S-adenosylhomocysteine
3evd
Crystal structure of gtp complex of yellow fever virus methyltransferase and s-adenosyl-l-homocysteine
Source: Yellow fever virus. Organism_taxid: 11090. Strain: 17d. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (261 residues) CATH domain: 3.40.50.150
Bound ligands:   Het Group GTP is 47.76% similar to enzyme reactant G(5')pppR-RNA
  Het Group SAH corresponds to enzyme product S-adenosylhomocysteine
3eve
Crystal structure of gpppa complex of yellow fever virus methyltransferase and s-adenosyl-l-homocysteine
Source: Yellow fever virus. Organism_taxid: 11090. Strain: 17d. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (261 residues) CATH domain: 3.40.50.150
Bound ligands:   Het Group G3A is 51.95% similar to enzyme reactant G(5')pppR-RNA
  Het Group SAH corresponds to enzyme product S-adenosylhomocysteine
3evf
Crystal structure of me7-gpppa complex of yellow fever virus methyltransferase and s-adenosyl-l-homocysteine
Source: Yellow fever virus. Organism_taxid: 11090. Strain: 17d. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (261 residues) CATH domain: 3.40.50.150
Bound ligand:   Het Group SAH corresponds to enzyme product S-adenosylhomocysteine
3evg
Crystal structure of dengue-2 virus methyltransferase complexed with s-adenosyl-l-homocysteine
Source: Dengue virus 2 16681-pdk53. Organism_taxid: 31635. Strain: 16681. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (257 residues) CATH domain: 3.40.50.150
Bound ligand:   Het Group SAH corresponds to enzyme product S-adenosylhomocysteine
3ixy
The pseudo-atomic structure of dengue immature virus in complex with fab fragments of the anti-fusion loop antibody e53
Source: Dengue virus 2. Organism_taxid: 11060. Strain: denv2. Expressed in: aedes albopictus. Expression_system_taxid: 7160. Expression_system_cell_line: c6/36. Mus musculus. Organism_taxid: 10090. Expressed in: escherichia coli.
Chains: A, B, C (390 residues)
3j27
Cryoem structure of dengue virus
Source: Dengue virus 2. Denv-2. Organism_taxid: 11060. Strain: new guinea. Cell_line: mosquito cells c6/36. Cell_line: mosquito cells c6/36
Chains: A, B, C, D, E, F (495 residues) CATH domains: 2.60.98.10 3.30.67.10 3.30.387.10
3j2p
Cryoem structure of dengue virus capsid protein heterotetram
Source: Dengue virus 2. Denv-2. Organism_taxid: 11060. Strain: new guinea. Cell_line: mosquito cells c6/36. Cell_line: mosquito cells c6/36
Chains: A, B, C, D (495 residues) CATH domains: 2.60.98.10 3.30.67.10 3.30.387.10
3l6p
Crystal structure of dengue virus 1 ns2b/ns3 protease
Source: Dengue virus 1. Organism_taxid: 11053. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (196 residues) CATH domain: 2.40.10.120
3lkw
Crystal structure of dengue virus 1 ns2b/ns3 protease active site mutant
Source: Dengue virus 1. Organism_taxid: 11053. Gene: ns2b/ns3. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (211 residues) CATH domain: 2.40.10.120
3p54
Crystal structure of the japanese encephalitis virus envelop strain sa-14-14-2.
Source: Japanese encephalitis virus. Organism_taxid: 11072. Strain: sa-14-14-2. Gene: envelope protein e. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (404 residues) CATH domains: 2.60.98.10 3.30.67.10 3.30.387.10 2.60.40.350
3p8z
Dengue methyltransferase bound to a sam-based inhibitor
Source: Dengue virus 3. Organism_taxid: 11069. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, C (257 residues) CATH domain: 3.40.50.150
3p97
Dengue 3 ns5 methyltransferase bound to the substrate s-aden methionine
Source: Dengue virus 3. Organism_taxid: 11069. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, C (256 residues) CATH domain: 3.40.50.150
3u1i
Dengue virus protease covalently bound to a peptide
Source: Dengue virus 3. Denv-3. Organism_taxid: 408693. Strain: singapore/8120/1995. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: synthetic peptide
Chains: A, B, C, D (39 residues)
3u1j
Aprotinin bound to dengue virus protease
Source: Dengue virus 3. Denv-3. Organism_taxid: 408693. Strain: singapore/8120/1995. Expressed in: escherichia coli. Expression_system_taxid: 562. Bos taurus. Bovine. Organism_taxid: 9913
Chains: A, B (20 residues)
3uaj
Crystal structure of the envelope glycoprotein ectodomain fr virus serotype 4 in complex with the fab fragment of the ch monoclonal antibody 5h2
Source: Dengue virus 4. Organism_taxid: 11070. Strain: myanmar 1976. Gene: envelope. Expressed in: drosophila melanogaster. Expression_system_taxid: 7227. Pan troglodytes. Chimpanzee. Organism_taxid: 9598.
Chains: B, A (371 residues) CATH domains: 2.60.98.10 3.30.67.10 3.30.387.10 2.60.40.350
3uc0
Crystal structure of domain i of the envelope glycoprotein e from dengue virus serotype 4 in complex with the fab fragme chimpanzee monoclonal antibody 5h2
Source: Dengue virus 4. Organism_taxid: 11070. Strain: myanmar 1976. Gene: envelope. Expressed in: drosophila melanogaster. Expression_system_taxid: 7227. Pan troglodytes. Chimpanzee. Organism_taxid: 9598.
Chains: A, B (111 residues) CATH domain: 2.60.98.10
3uyp
Crystal structure of the dengue virus serotype 4 envelope pr domain iii in complex with the variable domains of mab 4e11
Source: Mus musculus. Mouse. Organism_taxid: 10090. Expressed in: escherichia coli. Expression_system_taxid: 562. Dengue virus 4. Organism_taxid: 11070. Strain: myanmar 1976.
Chain: B (96 residues) CATH domain: 2.60.40.350
3uze
Crystal structure of the dengue virus serotype 3 envelope pr domain iii in complex with the variable domains of mab 4e11
Source: Mus musculus. Mouse. Organism_taxid: 10090. Expressed in: escherichia coli. Expression_system_taxid: 562. Dengue virus 3. Organism_taxid: 11069. Strain: thailand/pah881/1988. Gene: e.
Chains: C, D (94 residues) CATH domain: Unassigned
3uzq
Crystal structure of the dengue virus serotype 1 envelope pr domain iii in complex with the variable domains of mab 4e11
Source: Mus musculus. Mouse. Organism_taxid: 10090. Expressed in: escherichia coli. Expression_system_taxid: 562. Dengue virus 1. Organism_taxid: 11053. Strain: guiana/fga89/1989.
Chain: B (95 residues) CATH domain: Unassigned
3uzv
Crystal structure of the dengue virus serotype 2 envelope pr domain iii in complex with the variable domains of mab 4e11
Source: Dengue virus 2. Denv-2. Organism_taxid: 11064. Strain: jamaica/1409/1983. Expressed in: escherichia coli. Expression_system_taxid: 562. Mus musculus. Mouse. Organism_taxid: 10090.
Chain: A (97 residues) CATH domain: Unassigned
3vtt
High resolution crystal structure of dengue 3 envelope prote iii (ed3)
Source: Dengue virus type 3. Denv-3. Organism_taxid: 408870. Strain: philippines/h87/1956. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (100 residues) CATH domain: Unassigned
3we1
Crystal structure of dengue 4 envelope protein domain iii (e
Source: Dengue virus type 4. Denv-4. Organism_taxid: 408871. Strain: dominica/814669/1981. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (97 residues) CATH domain: Unassigned
3zko
The structure of "breathing" dengue virus.
Source: Dengue virus 2. Organism_taxid: 11060. Strain: new guinea c
Chains: A, B, C (394 residues)
4al8
Structure of dengue virus diii in complex with fab 2h12
Source: Dengue virus. Organism_taxid: 12637. Expressed in: escherichia coli. Expression_system_taxid: 562. Homo sapiens. Organism_taxid: 9606. Other_details: hybridoma. Other_details: hybridoma
Chain: C (98 residues) CATH domain: Unassigned
4am0
Structure of dengue virus strain 4 diii in complex with fab 2h12
Source: Homo sapiens, mus musculus. Human, house mouse. Organism_taxid: 9606, 10090. Dengue virus. Organism_taxid: 11070. Strain: 4. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: Q, R, S, T (91 residues) CATH domain: Unassigned
4cbf
Near-atomic resolution cryo-em structure of dengue serotype 4 virus
Source: Dengue virus 2. Organism_taxid: 11060. Strain: thailand/ngs-c/1944 (denv-2). Expressed in: drosophila melanogaster. Expression_system_taxid: 7227. Expression_system_cell_line: c6/36. Dengue virus 4. Organism_taxid: 11070. Strain: sg/06k2270dk1/2005.
Chain: C (495 residues)
4ckb
Vaccinia virus capping enzyme complexed with gtp and sah
Source: Vaccinia virus. Organism_taxid: 10245. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: star plyss.
Chains: A, D (809 residues)
4ckc
Vaccinia virus capping enzyme complexed with sah (monoclinic
Source: Vaccinia virus. Organism_taxid: 10245. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: star plyss.
Chains: A, D (819 residues)
4cke
Vaccinia virus capping enzyme complexed with sah in p1 form
Source: Vaccinia virus. Organism_taxid: 10245. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: star plyss.
Chains: A, D (802 residues)
4fg0
Structure of the st. Louis encephalitis virus envelope prote fusogenic trimer conformation.
Source: St. Louis encephalitis virus. Organism_taxid: 11080. Strain: st. Louis encephalitis virus, strain ms1-7. Gene: envelope protein e. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (386 residues) CATH domains: 2.60.98.10 3.30.67.10 3.30.387.10
4gsx
High resolution structure of dengue virus serotype 1 se cont stem
Source: Dengue virus 1. Denv-1. Organism_taxid: 11059. Strain: wp74. Gene: envelope protein. Expressed in: trichoplusia ni. Expression_system_taxid: 7111.
Chains: A, B (390 residues) CATH domains: 2.60.98.10 3.30.67.10 3.30.387.10
4gt0
Structure of dengue virus serotype 1 se containing stem to r
Source: Dengue virus 1. Denv-1. Organism_taxid: 11059. Strain: wp74. Gene: envelope protein. Expressed in: trichoplusia ni. Expression_system_taxid: 7111.
Chains: A, B (390 residues) CATH domains: 2.60.98.10 3.30.67.10 3.30.387.10
4hdg
Crystal structure of viral rdrp in complex with gtp
Source: Japanese encephalitis virus. Organism_taxid: 11072. Strain: p20778. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (612 residues) CATH domains: Unassigned Unassigned Unassigned Unassigned
Bound ligand:   Het Group GTP is 47.76% similar to enzyme reactant G(5')pppR-RNA
4hdh
Crystal structure of viral rdrp in complex with atp
Source: Japanese encephalitis virus. Organism_taxid: 11072. Strain: p20778. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (613 residues) CATH domains: Unassigned Unassigned Unassigned Unassigned
Bound ligand:   Het Group ATP is 46.27% similar to enzyme reactant G(5')pppR-RNA
4k6m
Crystal structure of the full-length japanese encephalitis v
Source: Japanese encephalitis virus. Organism_taxid: 11072. Strain: at31. Gene: ns5. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (888 residues) CATH domain: 3.40.50.150
Bound ligand:   Het Group SAH corresponds to enzyme product S-adenosylhomocysteine
4mtp
Rdrp from japanesese encephalitis virus
Source: Japanese encephalitis virus. Organism_taxid: 11072. Gene: ns5. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (591 residues) CATH domains: Unassigned Unassigned Unassigned Unassigned
4o6b
Dengue type2 virus non-structural protein 1 (ns1) form 1 cry
Source: Dengue virus 2. Denv-2. Organism_taxid: 31634. Strain: thailand/16681/1984. Gene: ns1. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108.
Chains: A, B (319 residues)