_EC 2.1.1.282 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))- 6 PDB entries  
EC 2.-.-.- Transferases. [17,949 PDB entries]
EC 2.1.-.- Transferring one-carbon groups. [1,711 PDB entries]
EC 2.1.1.- Methyltransferases. [1,381 PDB entries]
EC 2.1.1.282 tRNA(Phe) 7-((3-amino-3-carboxypropyl)-4-demethylwyosine(37)-N(4))- [6 PDB entries]    
1tlj

Reaction: S-adenosyl-L-methionine + 7-((3S)-(3-amino-3-carboxypropyl))-4- demethylwyosine(37) in tRNA(Phe) = S-adenosyl-L-homocysteine + 7-((3S)- (3-amino-3-carboxypropyl))wyosine(37) in tRNA(Phe).
 


S-adenosyl-L-methionine
+ 7-((3S)-(3-amino-3-carboxypropyl))-4- demethylwyosine(37) in tRNA(Phe)
=
S-adenosyl-L-homocysteine
+ 7-((3S)- (3-amino-3-carboxypropyl))wyosine(37) in tRNA(Phe)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): tRNA-yW synthesizing enzyme-3.
Comments: The enzyme is involved in the biosynthesis of hypermodified tricyclic bases found at position 37 of certain tRNAs. These modifications are important for translational reading-frame maintenance. The enzyme is found in all eukaryotes and in some archaea, but not in bacteria. The eukaryotic enzyme is involved in the biosynthesis of wybutosine.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 6 PDB entries in enzyme class E.C.2.1.1.282

  PDB code Protein
1tlj
Crystal structure of conserved protein of unknown function sso0622 from sulfolobus solfataricus
Source: Sulfolobus solfataricus. Organism_taxid: 2287. Gene: sso0622, c08_028. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (189 residues) CATH domain: 3.30.1960.10
2drv
Structure of ph1069 protein from pyrococcus horikoshii ot3
Source: Pyrococcus horikoshii. Organism_taxid: 70601. Strain: ot3. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (191 residues) CATH domain: 3.30.1960.10
2dvk
Crystal structure of hypothetical protein from aeropyrum per
Source: Aeropyrum pernix. Organism_taxid: 56636. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (166 residues) CATH domain: 3.30.1960.10
2it2
Structure of ph1069 protein from pyrococcus horikoshii
Source: Pyrococcus horikoshii. Organism_taxid: 53953. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (189 residues) CATH domain: 3.30.1960.10
2it3
Structure of ph1069 protein from pyrococcus horikoshii
Source: Pyrococcus horikoshii. Organism_taxid: 53953. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (197 residues) CATH domain: 3.30.1960.10
2qg3
Crystal structure of a tyw3 methyltransferase-like protein ( from archaeoglobus fulgidus dsm 4304 at 1.95 a resolution
Source: Archaeoglobus fulgidus dsm 4304. Organism_taxid: 224325. Strain: vc-16, dsm 4304, jcm 9628, nbrc 100126. Atcc: 49558. Gene: 2648472, af_2059. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (195 residues) CATH domain: 3.30.1960.10