_EC 2.1.1.266 23S rRNA (adenine(2030)-N(6))-methyltransferase. 4 PDB entries  
EC 2.-.-.- Transferases. [17,500 PDB entries]
EC 2.1.-.- Transferring one-carbon groups. [1,666 PDB entries]
EC 2.1.1.- Methyltransferases. [1,337 PDB entries]
EC 2.1.1.266 23S rRNA (adenine(2030)-N(6))-methyltransferase. [4 PDB entries]    
2oo3

Reaction: S-adenosyl-L-methionine + adenine(2030) in 23S rRNA = S-adenosyl-L- homocysteine + N(6)-methyladenine(2030) in 23S rRNA.
 


S-adenosyl-L-methionine
+ adenine(2030) in 23S rRNA
=
S-adenosyl-L- homocysteine
+ N(6)-methyladenine(2030) in 23S rRNA
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): M(6)A(2030) methyltransferase.
Comments: The recombinant RlmJ protein is most active in methylating deproteinized 23S ribosomal subunit, and does not methylate the completely assembled 50S subunits.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 4 PDB entries in enzyme class E.C.2.1.1.266

  PDB code Protein
2oo3
Crystal structure of protein lpl1258 from legionella pneumop philadelphia 1, pfam duf519
Source: Legionella pneumophila subsp. Pneumoph organism_taxid: 91891. Strain: lens, philadelphia 1. Atcc: 33152. Gene: lpl1258, lpg1296, dsm 7513. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (267 residues) CATH domain: 3.40.50.150
4blu
Crystal structure of escherichia coli 23s rrna (a2030-n6)- methyltransferase rlmj
Source: Escherichia coli. Organism_taxid: 83333. Strain: k-12. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (279 residues) CATH domain: 3.40.50.150
4blv
Crystal structure of escherichia coli 23s rrna (a2030-n6)- methyltransferase rlmj in complex with s-adenosylmethionine
Source: Escherichia coli. Organism_taxid: 83333. Strain: k-12. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (280 residues) CATH domain: 3.40.50.150
Bound ligand:   Het Group SAM corresponds to enzyme reactant S-adenosyl-L-methionine
4blw
Crystal structure of escherichia coli 23s rrna (a2030-n6)- methyltransferase rlmj in complex with s- adenosylhomocysteine (adohcy) and adenosine monophosphate ( amp)
Source: Escherichia coli. Organism_taxid: 83333. Strain: k-12. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (280 residues) CATH domain: 3.40.50.150
Bound ligand:   Het Group SAH corresponds to enzyme product S-adenosylhomocysteine