_EC 2.1.1.262 Squalene methyltransferase. 0 PDB entries  
EC 2.-.-.- Transferases. [16,521 PDB entries]
EC 2.1.-.- Transferring one-carbon groups. [1,566 PDB entries]
EC 2.1.1.- Methyltransferases. [1,227 PDB entries]
EC 2.1.1.262 Squalene methyltransferase. [-]    

Reaction: 2 S-adenosyl-L-methionine + squalene = 2 S-adenosyl-L-homocysteine + 3,22-dimethyl-1,2,23,24-tetradehydro-2,3,22,23-tetrahydrosqualene.
 


2 × S-adenosyl-L-methionine
+
squalene
=
2 × S-adenosyl-L-homocysteine
+ 3,22-dimethyl-1,2,23,24-tetradehydro-2,3,22,23-tetrahydrosqualene
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Comments: Two isoforms differing in their specificity were isolated from the green alga Botryococcus braunii BOT22. TMT-1 gave more of the dimethylated form whereas TMT2 gave more of the monomethylated form.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are no PDB entries in enzyme class E.C.2.1.1.262