_EC 2.1.1.255 Geranyl diphosphate 2-C-methyltransferase. 5 PDB entries  
EC 2.-.-.- Transferases. [17,949 PDB entries]
EC 2.1.-.- Transferring one-carbon groups. [1,711 PDB entries]
EC 2.1.1.- Methyltransferases. [1,381 PDB entries]
EC 2.1.1.255 Geranyl diphosphate 2-C-methyltransferase. [5 PDB entries]    
3vc1

Reaction: S-adenosyl-L-methionine + geranyl diphosphate = S-adenosyl-L-homocysteine + (E)-2-methylgeranyl diphosphate.
 


S-adenosyl-L-methionine
+
geranyl diphosphate
=
S-adenosyl-L-homocysteine
+ (E)-2-methylgeranyl diphosphate
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): 2-methyl-GPP synthase. Geranyl pyrophosphate methyltransferase. Gpp methyltransferase. Gppmt. Mgpps.
Cofactor(s): Mg(2+).
Comments: This enzyme, along with Ec 4.2.3.118, produces 2-methylisoborneol, an odiferous compound produced by soil microorganisms with a strong earthy/musty odor. Formerly Ec 2.1.1.n6.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 5 PDB entries in enzyme class E.C.2.1.1.255

  PDB code Protein
3vc1
Crystal structure of geranyl diphosphatE C-methyltransferase streptomyces coelicolor a3(2) in complex with mg2+, geranyl thiolodiphosphate, and s-adenosyl-l-homocysteine
Source: Streptomyces coelicolor. Organism_taxid: 100226. Strain: a3(2). Gene: orf4, scbac12c8.02, sco7701. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D, E, F, G, H, I, J, K, L (277 residues) CATH domain: 3.40.50.150
3vc2
Crystal structure of geranyl diphosphatE C-methyltransferase streptomyces coelicolor a3(2) in complex with mg2+, geranyl diphosphate, and s-adenosyl-l-homocysteine
Source: Streptomyces coelicolor. Organism_taxid: 100226. Strain: a3(2). Gene: orf4, scbac12c8.02, sco7701. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D, E, F, G, H, I, J, K, L (277 residues) CATH domain: 3.40.50.150
4f84
Structure analysis of geranyl diphosphate methyltransferase with sam
Source: Streptomyces lasaliensis. Organism_taxid: 324833. Gene: gdpmt. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (248 residues) CATH domain: 3.40.50.150
4f85
Structure analysis of geranyl diphosphate methyltransferase
Source: Streptomyces lasaliensis. Organism_taxid: 324833. Gene: gdpmt. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (246 residues) CATH domain: 3.40.50.150
4f86
Structure analysis of geranyl diphosphate methyltransferase with gpp and sinefungin
Source: Streptomyces lasaliensis. Organism_taxid: 324833. Gene: gdpmt. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D, E, F, G, H, I, J, K, L (275 residues) CATH domain: 3.40.50.150