_EC 2.1.1.251 Methylated-thiol--coenzyme M methyltransferase. 0 PDB entries  
EC 2.-.-.- Transferases. [7,088 PDB entries]
EC 2.1.-.- Transferring one-carbon groups. [643 PDB entries]
EC 2.1.1.- Methyltransferases. [511 PDB entries]
EC 2.1.1.251 Methylated-thiol--coenzyme M methyltransferase. [-]    

Reaction: Methanethiol + coenzyme M = methyl-CoM + hydrogen sulfide.
 


Methanethiol
+
coenzyme M
=
methyl-CoM
+ hydrogen sulfide
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Comments: The enzyme, which is involved in methanogenesis from methylated thiols, such as methane thiol, dimethyl sulfide, and 3-S- methylmercaptopropionate, catalyzes two successive steps - the transfer of a methyl group from the substrate to the cobalt cofactor of a methylated-thiol-specific corrinoid protein (MtsB), and the subsequent transfer of the methyl group from the corrinoid protein to coenzyme M. With most other methanogenesis substrates this process is carried out by two different enzymes (for example, Ec 2.1.1.90 and Ec 2.1.1.246). The cobalt is oxidized during methylation from the Co(I) state to the
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There are no PDB entries in enzyme class E.C.2.1.1.251