_EC 2.1.1.222 2-polyprenyl-6-hydroxyphenol methylase. 2 PDB entries  
EC 2.-.-.- Transferases. [17,949 PDB entries]
EC 2.1.-.- Transferring one-carbon groups. [1,711 PDB entries]
EC 2.1.1.- Methyltransferases. [1,381 PDB entries]
EC 2.1.1.222 2-polyprenyl-6-hydroxyphenol methylase. [2 PDB entries]    
4kdc

Reaction: S-adenosyl-L-methionine + 3-(all-trans-polyprenyl)benzene-1,2-diol = S-adenosyl-L-homocysteine + 2-methoxy-6-(all-trans-polyprenyl)phenol.
 


S-adenosyl-L-methionine
+ 3-(all-trans-polyprenyl)benzene-1,2-diol
=
S-adenosyl-L-homocysteine
+ 2-methoxy-6-(all-trans-polyprenyl)phenol
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): 2-octaprenyl-6-hydroxyphenol methylase.
Comments: UbiG catalyzes both methylation steps in ubiquinone biosynthesis in Escherichia coli. The second methylation is classified as Ec 2.1.1.64. In eukaryotes Coq3 catalyzes the two methylation steps in ubiquinone biosynthesis. However, while the second methylation is common to both enzymes, the first methylation by Coq3 occurs at a different position within the pathway, and thus involves a different substrate and is classified as Ec 2.1.1.114. The substrate of the eukaryotic enzyme (3,4-dihydroxy-5-all-trans-
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 2 PDB entries in enzyme class E.C.2.1.1.222

  PDB code Protein
4kdc
Crystal structure of ubig
Source: Escherichia coli. Organism_taxid: 83333. Strain: k12. Gene: ubig, pufx, yfab, b2232, jw2226. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (217 residues) CATH domain: Unassigned
4kdr
Crystal structure of ubig/sah complex
Source: Escherichia coli. Organism_taxid: 83333. Strain: k12. Gene: ubig, pufx, yfab, b2232, jw2226. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (208 residues) CATH domain: Unassigned