_EC 2.1.1.2 Guanidinoacetate N-methyltransferase. 7 PDB entries  
EC 2.-.-.- Transferases. [17,772 PDB entries]
EC 2.1.-.- Transferring one-carbon groups. [1,717 PDB entries]
EC 2.1.1.- Methyltransferases. [1,369 PDB entries]
EC 2.1.1.2 Guanidinoacetate N-methyltransferase. [7 PDB entries]    
1khh

Pathway: Creatine Biosynthesis
Reaction: S-adenosyl-L-methionine + guanidinoacetate = S-adenosyl-L-homocysteine + creatine.
 


S-adenosyl-L-methionine
+
guanidinoacetate
=
S-adenosyl-L-homocysteine
+
creatine
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 7 PDB entries in enzyme class E.C.2.1.1.2

  PDB code Protein
1khh
Crystal structure of guanidinoacetate methyltransferase from rat liver: a template structure of protein arginine methyltransferase
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Organ: liver. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (193 residues) CATH domain: 3.40.50.150
Bound ligand:   Het Group SAH corresponds to enzyme product S-adenosylhomocysteine
1p1b
Guanidinoacetate methyltransferase
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Gene: gamt. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D (193 residues) CATH domain: 3.40.50.150
Bound ligand:   Het Group SAH corresponds to enzyme product S-adenosylhomocysteine
1p1c
Guanidinoacetate methyltransferase with gd ion
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Gene: gamt. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (193 residues) CATH domain: 3.40.50.150
Bound ligand:   Het Group SAH corresponds to enzyme product S-adenosylhomocysteine
1xcj
Guanidinoacetate methyltransferase containing s- adenosylhomocysteine and guanidinoacetate
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Tissue: liver. Gene: gamt. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (229 residues) CATH domain: 3.40.50.150
Bound ligands:   Het Group NMG corresponds to enzyme reactant guanidinoacetate
  Het Group SAH corresponds to enzyme product S-adenosylhomocysteine
1xcl
Guanidinoacetate methyltransferase containing s- adenosylhomocysteine and guanidine
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Tissue: liver. Gene: gamt. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (229 residues) CATH domain: 3.40.50.150
Bound ligands:   Het Group GAI is 50.00% similar to enzyme reactant guanidinoacetate
  Het Group SAH corresponds to enzyme product S-adenosylhomocysteine
1zx0
Human guanidinoacetate n-methyltransferase with sah
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gamt. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B, C, D (229 residues) CATH domain: 3.40.50.150
Bound ligand:   Het Group SAH is 96.00% similar to enzyme reactant S-adenosyl-L-methionine
3orh
Human guanidinoacetate n-methyltransferase with sah
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: gamt. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (230 residues) CATH domain: 3.40.50.150
Bound ligand:   Het Group SAH corresponds to enzyme product S-adenosylhomocysteine