_EC 2.1.1.187 23S rRNA (guanine(745)-N(1))-methyltransferase. 1 PDB entries  
EC 2.-.-.- Transferases. [17,943 PDB entries]
EC 2.1.-.- Transferring one-carbon groups. [1,710 PDB entries]
EC 2.1.1.- Methyltransferases. [1,380 PDB entries]
EC 2.1.1.187 23S rRNA (guanine(745)-N(1))-methyltransferase. [1 PDB entries]    
1p91

Reaction: S-adenosyl-L-methionine + guanine(745) in 23S rRNA = S-adenosyl-L- homocysteine + N(1)-methylguanine(745) in 23S rRNA.
 


S-adenosyl-L-methionine
+ guanine(745) in 23S rRNA
=
S-adenosyl-L- homocysteine
+ N(1)-methylguanine(745) in 23S rRNA
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): 23S rRNA m(1)G(745) methyltransferase. Ribosomal RNA(m(1)G)-methylase.
Comments: The enzyme specifically methylates guanine(745) at N(1) in 23S rRNA. Formerly Ec 2.1.1.51.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 1 PDB entries in enzyme class E.C.2.1.1.187

  PDB code Protein
1p91
Crystal structure of rlma(i) enzyme: 23s rrna n1-g745 methyltransferase (northeast structural genomics consortium target er19)
Source: Escherichia coli. Organism_taxid: 562. Gene: rrma or b1822. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (268 residues) CATH domain: 3.40.50.150
Bound ligand:   Het Group SAM corresponds to enzyme reactant S-adenosyl-L-methionine