_EC 2.1.1.185 23S rRNA (guanosine(2251)-2'-O)-methyltransferase. 1 PDB entries  
EC 2.-.-.- Transferases. [17,943 PDB entries]
EC 2.1.-.- Transferring one-carbon groups. [1,710 PDB entries]
EC 2.1.1.- Methyltransferases. [1,380 PDB entries]
EC 2.1.1.185 23S rRNA (guanosine(2251)-2'-O)-methyltransferase. [1 PDB entries]    
1gz0

Reaction: S-adenosyl-L-methionine + guanosine(2251) in 23S rRNA = S-adenosyl-L- homocysteine + 2'-O-methylguanosine(2251) in 23S rRNA.
 


S-adenosyl-L-methionine
+ guanosine(2251) in 23S rRNA
=
S-adenosyl-L- homocysteine
+ 2'-O-methylguanosine(2251) in 23S rRNA
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Comments: The enzyme catalyzes the methylation of guanosine(2251), a modification conserved in the peptidyltransferase domain of 23S rRNA.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 1 PDB entries in enzyme class E.C.2.1.1.185

  PDB code Protein
1gz0
23s ribosomal RNA g2251 2'o-methyltransferase rlmb
Source: Escherichia coli. Organism_taxid: 562. Strain: mc1061 p3. Atcc: 47035. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D, E, F, G, H (242 residues) CATH domains: 3.30.1330.30 3.40.1280.10