_EC 2.1.1.164 Demethylrebeccamycin-D-glucose O-methyltransferase. 1 PDB entries  
EC 2.-.-.- Transferases. [17,949 PDB entries]
EC 2.1.-.- Transferring one-carbon groups. [1,711 PDB entries]
EC 2.1.1.- Methyltransferases. [1,381 PDB entries]
EC 2.1.1.164 Demethylrebeccamycin-D-glucose O-methyltransferase. [1 PDB entries]    
3bus

Reaction: 4'-demethylrebeccamycin + S-adenosyl-L-methionine = rebeccamycin + S-adenosyl-L-homocysteine.
 

4'-demethylrebeccamycin
+
S-adenosyl-L-methionine
= rebeccamycin
+
S-adenosyl-L-homocysteine
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Comments: Catalyzes the last step in the biosynthesis of rebeccamycin, an indolocarbazole alkaloid produced by the bacterium Lechevalieria aerocolonigenes. The enzyme is able to use a wide variety substrates, tolerating variation on the imide heterocycle, deoxygenation of the sugar moiety, and even indolocarbazole glycoside anomers.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 1 PDB entries in enzyme class E.C.2.1.1.164

  PDB code Protein
3bus
Crystal structure of rebm
Source: Lechevalieria aerocolonigenes. Organism_taxid: 68170. Gene: rbmf, rebm. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (251 residues) CATH domain: 3.40.50.150
Bound ligand:   Het Group SAH corresponds to enzyme product S-adenosylhomocysteine