_EC Glycine/sarcosine N-methyltransferase. 0 PDB entries  
EC 2.-.-.- Transferases. [7,088 PDB entries]
EC 2.1.-.- Transferring one-carbon groups. [643 PDB entries]
EC 2.1.1.- Methyltransferases. [511 PDB entries]
EC Glycine/sarcosine N-methyltransferase. [-]    

Reaction: 2 S-adenosyl-L-methionine + glycine = 2 S-adenosyl-L-homocysteine + N,N-dimethylglycine.

2 × S-adenosyl-L-methionine
2 × S-adenosyl-L-homocysteine
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): Glycine sarcosine N-methyltransferase. Glycine-sarcosine methyltransferase. Gmt. Gsmt.
Comments: Cells of the oxygen-evolving halotolerant cyanobacterium Aphanocthece halophytica synthesize betaine from glycine by a three-step methylation process. This is the first enzyme and it leads to the formation of either sarcosine or N,N-dimethylglycine, which is further methylated to yield betaine (N,N,N-trimethylglycine) by the action of ec Differs from Ec, as it can further methylate the product of the first reaction. Acetate, dimethylglycine and S-adenosyl-L-homocysteine can inhibit the reaction.
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There are no PDB entries in enzyme class E.C.