_EC 2.1.1.154 Isoliquiritigenin 2'-O-methyltransferase. 2 PDB entries  
EC 2.-.-.- Transferases. [17,943 PDB entries]
EC 2.1.-.- Transferring one-carbon groups. [1,710 PDB entries]
EC 2.1.1.- Methyltransferases. [1,380 PDB entries]
EC 2.1.1.154 Isoliquiritigenin 2'-O-methyltransferase. [2 PDB entries]    
1fp1

Pathway: Daidzein Biosynthesis
Reaction: S-adenosyl-L-methionine + isoliquiritigenin = S-adenosyl-L-homocysteine + 2'-O-methylisoliquiritigenin.
 


S-adenosyl-L-methionine
+
isoliquiritigenin
=
S-adenosyl-L-homocysteine
+
2'-O-methylisoliquiritigenin
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): Chalcone Omt. Chmt.
Comments: Not identical to Ec 2.1.1.65. While Ec 2.1.1.154 can use licodione as a substrate, Ec 2.1.1.65 cannot use isoliquiritigenin as a substrate.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 2 PDB entries in enzyme class E.C.2.1.1.154

  PDB code Protein
1fp1
Crystal structure analysis of chalcone o-methyltransferase
Source: Medicago sativa. Organism_taxid: 3879. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: D (340 residues) CATH domains: 1.10.10.10 3.40.50.150
Bound ligands:   Het Group HCC corresponds to enzyme reactant isoliquiritigenin
  Het Group SAH corresponds to enzyme product S-adenosylhomocysteine
1fpq
Crystal structure analysis of selenomethionine substituted c methyltransferase
Source: Medicago sativa. Organism_taxid: 3879. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (333 residues) CATH domains: 3.40.50.150 1.10.10.10
Bound ligand:   Het Group SAM corresponds to enzyme reactant S-adenosyl-L-methionine