_EC Trans-aconitate 3-methyltransferase. 1 PDB entries  
EC 2.-.-.- Transferases. [18,188 PDB entries]
EC 2.1.-.- Transferring one-carbon groups. [1,730 PDB entries]
EC 2.1.1.- Methyltransferases. [1,400 PDB entries]
EC Trans-aconitate 3-methyltransferase. [1 PDB entries]    

Pathway: trans-Aconitate methyltransferases
Reaction: S-adenosyl-L-methionine + trans-aconitate = S-adenosyl-L-homocysteine + (E)-2-(methoxycarbonylmethyl)butenedioate.

Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Comments: Also catalyzes the formation of the methyl monoester of cis- aconitate, isocitrate and citrate, but more slowly. While the enzyme from Saccharomyces cerevisiae forms (E)-2- (methoxycarbonylmethyl)butenedioate as the product, that from Escherichia coli forms (E)-3-(methoxycarbonyl)-pent-2-enedioate and is therefore classified as a separate enzyme (cf. Ec
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 1 PDB entries in enzyme class E.C.

  PDB code Protein
Crystal structure of trans-aconitate 3-methyltransferase from yeast
Source: Saccharomyces cerevisiae. Yeast. Organism_taxid: 4932. Gene: p32643, s000000977, sygp-orf63, tam1, tmt1, yer175c. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (299 residues) CATH domain: Unassigned
Bound ligands:   Het Group SAH corresponds to enzyme product S-adenosylhomocysteine
  Het Group T8N corresponds to enzyme product (E)-2-(methoxycarbonylmethyl)butenedioate