_EC 2.1.1.115 (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline N-methyltransferase. 0 PDB entries  
EC 2.-.-.- Transferases. [17,949 PDB entries]
EC 2.1.-.- Transferring one-carbon groups. [1,711 PDB entries]
EC 2.1.1.- Methyltransferases. [1,381 PDB entries]
EC 2.1.1.115 (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline N-methyltransferase. [-]    

Reaction: S-adenosyl-L-methionine + (RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline = S-adenosyl-L-homocysteine + N-methyl-(RS)-1-benzyl-1,2,3,4- tetrahydroisoquinoline.
 


S-adenosyl-L-methionine
+
(RS)-1-benzyl-1,2,3,4-tetrahydroisoquinoline
=
S-adenosyl-L-homocysteine
+
N-methyl-(RS)-1-benzyl-1,2,3,4- tetrahydroisoquinoline
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): (RS)-tetrahydrobenzylisoquinoline N-methyltransferase. Norreticuline N-methyltransferase.
Comments: Broad substrate specificity for (RS)-1-benzyl-1,2,3,4- tetrahydroisoquinolines; including coclaurine, norcoclaurine, isococlaurine, norarmepavine, norreticuline and tetrahydropapaverine. Both R- and S-enantiomers are methylated. Participates in the pathway leading to benzylisoquinoline alkaloid synthesis in plants. The physiological substrate is likely to be coclaurine. Was earlier termed norreticuline N-methyltransferase. However, norreticuline has not been found to occur in nature and that name does not reflect the broad specificity of the enzyme for (RS)-1-
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There are no PDB entries in enzyme class E.C.2.1.1.115