_EC 1.7.3.3 Factor independent urate hydroxylase. 66 PDB entries  
EC 1.-.-.- Oxidoreductases. [8,653 PDB entries]
EC 1.7.-.- Acting on other nitrogenous compounds as donors. [339 PDB entries]
EC 1.7.3.- With oxygen as acceptor. [79 PDB entries]
EC 1.7.3.3 Factor independent urate hydroxylase. [66 PDB entries]    
1j2g

Pathway: AMP Catabolism
Reaction: Urate + O(2) + H(2)O = 5-hydroxyisourate + H(2)O(2).
 


Urate
+
O(2)
+ H(2)O
=
5-hydroxyisourate
+
H(2)O(2)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): Urate oxidase. Uric acid oxidase. Uricase. Uricase Ii.
Comments: Was previously thought to be a copper protein, but it is now known that the enzymes from soybean (Glycine max), the mold Aspergillus flavus and Bacillus subtilis contains no copper nor any other transition-metal ion. The 5-hydroxyisourate formed decomposes spontaneously to form allantoin and CO(2), although there is an enzyme-catalyzed pathway in which Ec 3.5.2.17 catalyzes the first step. The enzyme is different from Ec 1.14.13.113.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 66 PDB entries in enzyme class E.C.1.7.3.3

  PDB code Protein
1j2g
Crystal structure of urate oxidase from bacillus sp. Tb-90 c crystallized with 8-azaxanthine
Source: Bacillus sp.. Organism_taxid: 36824. Strain: tb-90. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (306 residues) CATH domain: 3.10.270.10
Bound ligand:   Het Group AZA is 76.92% similar to enzyme reactant Urate
1r4s
Urate oxidase from aspergillus flavus complexed with its inh methyl uric acid
Source: Aspergillus flavus. Organism_taxid: 5059
Chain: A (296 residues) CATH domain: 3.10.270.10
Bound ligand:   Het Group MUA is 92.31% similar to enzyme reactant Urate
1r4u
Urate oxidase from aspergillus flavus complexed with its inh oxonic acid
Source: Aspergillus flavus. Organism_taxid: 5059
Chain: A (295 residues) CATH domain: 3.10.270.10
Bound ligand:   Het Group OXC is 71.43% similar to enzyme product 5-hydroxyisourate
1r51
Urate oxidase from aspergillus flavus complexed with its inh azaxanthin
Source: Aspergillus flavus. Organism_taxid: 5059
Chain: A (296 residues) CATH domain: 3.10.270.10
Bound ligand:   Het Group AZA is 76.92% similar to enzyme reactant Urate
1r56
Uncomplexed urate oxidase from aspergillus flavus
Source: Aspergillus flavus. Organism_taxid: 5059
Chains: A, B, C, D, E, F, G, H (295 residues) CATH domain: 3.10.270.10
1vax
Crystal structure of uricase from arthrobacter globiformis
Source: Arthrobacter globiformis. Organism_taxid: 1665
Chains: A, B, C, D, E, F, G, H (287 residues) CATH domain: 3.10.270.10
1vay
Crystal structure of uricase from arthrobacter globiformis with inhibitor 8-azaxanthine
Source: Arthrobacter globiformis. Organism_taxid: 1665
Chains: A, B, C, D, E, F, G, H (287 residues) CATH domain: 3.10.270.10
Bound ligand:   Het Group AZA is 71.00% similar to enzyme product 5-hydroxyisourate
1wrr
Urate oxidase from aspergillus flavus complexed with 5-amino uracil
Source: Aspergillus flavus. Organism_taxid: 5059. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932
Chain: A (295 residues) CATH domain: 3.10.270.10
Bound ligand:   Het Group UNC is 71.43% similar to enzyme reactant Urate
1ws2
Urate oxidase from aspergillus flavus complexed with 5,6- diaminouracil
Source: Aspergillus flavus. Organism_taxid: 5059. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932
Chains: A, B, C, D (296 residues) CATH domain: 3.10.270.10
Bound ligand:   Het Group URN is 83.00% similar to enzyme reactant Urate
1ws3
Urate oxidase from aspergillus flavus complexed with uracil
Source: Aspergillus flavus. Organism_taxid: 5059. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932
Chains: A, B, C, D (296 residues) CATH domain: 3.10.270.10
Bound ligand:   Het Group URA is 66.00% similar to enzyme reactant Urate
1xt4
Urate oxidase from aspergillus flavus complexed with guanine
Source: Aspergillus flavus. Organism_taxid: 5059. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932
Chain: A (295 residues) CATH domain: 3.10.270.10
Bound ligand:   Het Group GUN is 76.92% similar to enzyme reactant Urate
1xxj
Urate oxidase from aspergillus flavus complexed with 5- amino 6-nitro uracil
Source: Aspergillus flavus. Organism_taxid: 5059. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932
Chains: A, B, C, D (295 residues) CATH domain: 3.10.270.10
Bound ligand:   Het Group UNC is 71.00% similar to enzyme reactant Urate
1xy3
Urate oxidase from aspergillus flavus complexed with guanine
Source: Aspergillus flavus. Organism_taxid: 5059. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932
Chains: A, B, C, D, E, F, G, H (295 residues) CATH domain: 3.10.270.10
Bound ligand:   Het Group GUN is 76.00% similar to enzyme reactant Urate
2fub
Crystal structure of urate oxidase at 140 mpa
Source: Aspergillus flavus. Organism_taxid: 5059
Chain: A (295 residues) CATH domain: 3.10.270.10
Bound ligand:   Het Group AZA is 76.92% similar to enzyme reactant Urate
2fxl
Urate oxidase from aspergillus flavus complexed with allanto
Source: Aspergillus flavus. Organism_taxid: 5059. Gene: uaz, uox. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932
Chain: A (295 residues) CATH domain: 3.10.270.10
Bound ligand:   Het Group 2AL is 91.67% similar to enzyme reactant Urate
2iba
Urate oxidase from aspergillus flavus complexed with its inh azaxanthine
Source: Aspergillus flavus. Organism_taxid: 5059. Gene: uaz, uox. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932
Chain: A (296 residues) CATH domain: 3.10.270.10
Bound ligand:   Het Group AZA is 76.92% similar to enzyme reactant Urate
2ic0
Urate oxidase under 2.0 mpa pressure of xenon
Source: Aspergillus flavus. Organism_taxid: 5059. Gene: uaz, uox. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932
Chain: A (296 residues) CATH domain: 3.10.270.10
Bound ligand:   Het Group AZA is 76.92% similar to enzyme reactant Urate
2icq
Urate oxidase under 2.0 mpa pressure of nitrous oxide
Source: Aspergillus flavus. Organism_taxid: 5059
Chain: A (296 residues) CATH domain: 3.10.270.10
Bound ligand:   Het Group AZA is 76.92% similar to enzyme reactant Urate
2pes
Urate oxidase in complex with tris-dipicolinate lutetium
Source: Aspergillus flavus. Organism_taxid: 5059
Chain: A (295 residues) CATH domain: 3.10.270.10
Bound ligand:   Het Group AZA is 76.92% similar to enzyme reactant Urate
2yzb
Crystal structure of uricase from arthrobacter globiformis in complex with uric acid (substrate)
Source: Arthrobacter globiformis
Chains: A, B, C, D, E, F, G, H (287 residues) CATH domain: 3.10.270.10
Bound ligand:   Het Group URC is 71.00% similar to enzyme reactant urate
2yzc
Crystal structure of uricase from arthrobacter globiformis in complex with allantoate
Source: Arthrobacter globiformis
Chains: A, B, C, D, E, F, G, H (287 residues) CATH domain: 3.10.270.10
Bound ligand:   Het Group 1AL is 71.00% similar to enzyme reactant urate
2yzd
Crystal structure of uricase from arthrobacter globiformis in complex with 8-azaxanthin (inhibitor)
Source: Arthrobacter globiformis
Chains: A, B, C, D, E, F, G, H (287 residues) CATH domain: 3.10.270.10
Bound ligand:   Het Group AZA is 71.00% similar to enzyme product 5-hydroxyisourate
2yze
Crystal structure of uricase from arthrobacter globiformis
Source: Arthrobacter globiformis
Chains: A, B, C, D, E, F, G, H (287 residues) CATH domain: 3.10.270.10
2zka
Urate oxidase complexed with 8-azaxanthine under 1.0 mpa oxygen pressure
Source: Aspergillus flavus. Organism_taxid: 5059. Gene: uaz, uox. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932
Chain: A (296 residues) CATH domain: 3.10.270.10
Bound ligands:   Het Group AZA is 76.00% similar to enzyme reactant Urate
  Het Group OXY corresponds to enzyme reactant O(2)
2zkb
Urate oxidase complexed with 8-azaxanthine under 2.5 mpa oxygen pressure
Source: Aspergillus flavus. Organism_taxid: 5059. Gene: uaz, uox. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932
Chain: A (296 residues) CATH domain: 3.10.270.10
Bound ligands:   Het Group AZA is 76.00% similar to enzyme reactant Urate
  Het Group OXY corresponds to enzyme reactant O(2)
3bjp
Urate oxidase cyanide uric acid ternary complex
Source: Aspergillus flavus. Organism_taxid: 5059. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932
Chain: A (295 residues) CATH domain: 3.10.270.10
Bound ligand:   Het Group URC corresponds to enzyme reactant Urate
3bk8
Urate oxidase aza-xanthine complex in cyanide
Source: Aspergillus flavus. Organism_taxid: 5059. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932
Chain: A (295 residues) CATH domain: 3.10.270.10
Bound ligand:   Het Group AZA is 76.00% similar to enzyme reactant Urate
3cks
Urate oxidase complexed with 8-azaxanthine under 4.0 mpa oxygen pressure
Source: Aspergillus flavus. Organism_taxid: 5059. Gene: uaz, uox. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932
Chain: A (296 residues) CATH domain: 3.10.270.10
Bound ligands:   Het Group AZA is 76.00% similar to enzyme reactant Urate
  Het Group OXY corresponds to enzyme reactant O(2)
3cku
Urate oxidase from aspergillus flavus complexed with its inhibitor 8-azaxanthin and chloride
Source: Aspergillus flavus. Organism_taxid: 5059. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932
Chain: A (296 residues) CATH domain: 3.10.270.10
Bound ligand:   Het Group AZA is 76.00% similar to enzyme reactant Urate
3f2m
Urate oxidase complexed with 8-azaxanthine at 150 mpa
Source: Aspergillus flavus. Organism_taxid: 5059. Gene: uaz, uox. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932
Chain: A (296 residues) CATH domain: 3.10.270.10
Bound ligand:   Het Group AZA is 76.92% similar to enzyme reactant Urate
3gko
Crystal structure of urate oxydase using surfactant poloxamer 188 as a new crystallizing agent
Source: Aspergillus flavus. Organism_taxid: 5059. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932.
Chain: A (296 residues) CATH domain: 3.10.270.10
Bound ligand:   Het Group AZA is 76.00% similar to enzyme reactant Urate
3l8w
Urate oxidase from aspergillus flavus complexed with xanthin
Source: Aspergillus flavus. Organism_taxid: 5059. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932
Chain: A (296 residues) CATH domain: 3.10.270.10
Bound ligand:   Het Group XAN is 91.67% similar to enzyme reactant Urate
3l9g
Urate oxidase complexed with uric acid and chloride
Source: Aspergillus flavus. Organism_taxid: 5059. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932
Chain: A (296 residues) CATH domain: 3.10.270.10
Bound ligand:   Het Group URC corresponds to enzyme reactant Urate
3lbg
Urate oxidase complexed with 8-thio xanthine
Source: Aspergillus flavus. Organism_taxid: 5059. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932
Chain: A (296 residues) CATH domain: 3.10.270.10
Bound ligand:   Het Group 8TX is 84.62% similar to enzyme reactant Urate
3ld4
Urate oxidase complexed with 8-nitro xanthine
Source: Aspergillus flavus. Organism_taxid: 5059. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932
Chain: A (296 residues) CATH domain: 3.10.270.10
Bound ligand:   Het Group 8NX is 73.33% similar to enzyme reactant Urate
3obp
Anaerobic complex of urate oxidase with uric acid
Source: Aspergillus flavus. Organism_taxid: 5059. Gene: uaz, uox. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932
Chain: A (296 residues) CATH domain: 3.10.270.10
Bound ligand:   Het Group URC corresponds to enzyme reactant Urate
3p9f
Urate oxidase-azaxanthine-azide ternary complex
Source: Aspergillus flavus. Organism_taxid: 5059. Gene: uaz, uox. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932
Chain: A (296 residues) CATH domain: 3.10.270.10
Bound ligand:   Het Group AZA is 76.92% similar to enzyme reactant Urate
3p9o
Aerobic ternary complex of urate oxidase with azide and chlo
Source: Aspergillus flavus. Organism_taxid: 5059. Gene: uaz, uox. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932
Chain: A (296 residues) CATH domain: 3.10.270.10
3pjk
Urate oxidase under 1.0 mpa / 10 bars pressure of xenon
Source: Aspergillus flavus. Organism_taxid: 5059. Gene: uaz, uox. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932
Chain: A (296 residues) CATH domain: 3.10.270.10
Bound ligand:   Het Group AZA is 76.92% similar to enzyme reactant Urate
3pk3
Urate oxidase under 3.0 mpa / 30 bars pressure of nitrous ox
Source: Aspergillus flavus. Organism_taxid: 5059. Gene: uaz, uox. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932
Chain: A (296 residues) CATH domain: 3.10.270.10
Bound ligand:   Het Group AZA is 76.92% similar to enzyme reactant Urate
3pk4
Urate oxidase under 3.2 mpa / 32 bars pressure of xenon
Source: Aspergillus flavus. Organism_taxid: 5059. Gene: uaz, uox. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932
Chain: A (296 residues) CATH domain: 3.10.270.10
Bound ligand:   Het Group AZA is 76.92% similar to enzyme reactant Urate
3pk5
Urate oxidase under 0.1 mpa / 1 bar pressure of xenon
Source: Aspergillus flavus. Organism_taxid: 5059. Gene: uaz, uox. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932
Chain: A (296 residues) CATH domain: 3.10.270.10
Bound ligand:   Het Group AZA is 76.92% similar to enzyme reactant Urate
3pk6
Urate oxidase under 0.2 mpa / 2 bars pressure of xenon
Source: Aspergillus flavus. Organism_taxid: 5059. Gene: uaz, uox. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932
Chain: A (296 residues) CATH domain: 3.10.270.10
Bound ligand:   Het Group AZA is 76.92% similar to enzyme reactant Urate
3pk8
Urate oxidase under 0.5 mpa / 5 bars pressure of nitrous oxi
Source: Aspergillus flavus. Organism_taxid: 5059. Gene: uaz, uox. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932
Chain: A (296 residues) CATH domain: 3.10.270.10
Bound ligand:   Het Group AZA is 76.92% similar to enzyme reactant Urate
3pkf
Urate oxidase under 0.2 mpa / 2 bars pressure of equimolar m xenon and nitrous oxide
Source: Aspergillus flavus. Organism_taxid: 5059. Gene: uaz, uox. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932
Chain: A (296 residues) CATH domain: 3.10.270.10
Bound ligand:   Het Group AZA is 76.92% similar to enzyme reactant Urate
3pkg
Urate oxidase under 2 mpa / 20 bars pressure of xenon
Source: Aspergillus flavus. Organism_taxid: 5059. Gene: uaz, uox. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932
Chain: A (296 residues) CATH domain: 3.10.270.10
Bound ligand:   Het Group AZA is 76.92% similar to enzyme reactant Urate
3pkh
Urate oxidase under 1.5 mpa / 15 bars pressure of xenon
Source: Aspergillus flavus. Organism_taxid: 5059. Gene: uaz, uox. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932
Chain: A (296 residues) CATH domain: 3.10.270.10
Bound ligand:   Het Group AZA is 76.92% similar to enzyme reactant Urate
3pkk
Urate oxidase under 0.5 mpa / 5 bars pressure of xenon
Source: Aspergillus flavus. Organism_taxid: 5059. Gene: uaz, uox. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932
Chain: A (296 residues) CATH domain: 3.10.270.10
Bound ligand:   Het Group AZA is 76.92% similar to enzyme reactant Urate
3pkl
Urate oxidase under 0.8 mpa / 8 bars pressure of xenon
Source: Aspergillus flavus. Organism_taxid: 5059. Gene: uaz, uox. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932
Chain: A (296 residues) CATH domain: 3.10.270.10
Bound ligand:   Het Group AZA is 76.92% similar to enzyme reactant Urate
3pks
Urate oxidase under 1.5 mpa / 15 bars pressure of nitrous ox
Source: Aspergillus flavus. Organism_taxid: 5059. Gene: uaz, uox. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932
Chain: A (296 residues) CATH domain: 3.10.270.10
Bound ligand:   Het Group AZA is 76.92% similar to enzyme reactant Urate
3pkt
Urate oxidase under 2 mpa / 20 bars pressure of nitrous oxid
Source: Aspergillus flavus. Organism_taxid: 5059. Gene: uaz, uox. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932
Chain: A (296 residues) CATH domain: 3.10.270.10
Bound ligand:   Het Group AZA is 76.92% similar to enzyme reactant Urate
3pku
Urate oxidase under 1 mpa / 10 bars pressure of nitrous oxid
Source: Aspergillus flavus. Organism_taxid: 5059. Gene: uaz, uox. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932
Chain: A (296 residues) CATH domain: 3.10.270.10
Bound ligand:   Het Group AZA is 76.92% similar to enzyme reactant Urate
3ple
Urate oxidase under 0.5 mpa / 5 bars pressure of equimolar m xenon : nitrous oxide
Source: Aspergillus flavus. Organism_taxid: 5059. Gene: uaz, uox. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932
Chain: A (296 residues) CATH domain: 3.10.270.10
Bound ligand:   Het Group AZA is 76.92% similar to enzyme reactant Urate
3plg
Urate oxidase under 1.0 mpa / 10 bars pressure of equimolar xenon : nitrous oxide
Source: Aspergillus flavus. Organism_taxid: 5059. Gene: uaz, uox. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932
Chain: A (296 residues) CATH domain: 3.10.270.10
Bound ligand:   Het Group AZA is 76.92% similar to enzyme reactant Urate
3plh
Urate oxidase under 1.5 mpa / 15 bars pressure of equimolar xenon : nitrous oxide
Source: Aspergillus flavus. Organism_taxid: 5059. Gene: uaz, uox. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932
Chain: A (296 residues) CATH domain: 3.10.270.10
Bound ligand:   Het Group AZA is 76.92% similar to enzyme reactant Urate
3pli
Urate oxidase under 1.8 mpa / 18 bars pressure of equimolar xenon : nitrous oxide
Source: Aspergillus flavus. Organism_taxid: 5059. Gene: uaz, uox. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932
Chain: A (296 residues) CATH domain: 3.10.270.10
Bound ligand:   Het Group AZA is 76.92% similar to enzyme reactant Urate
3plj
Urate oxidase under 3.0 mpa / 30 bars pressure of equimolar xenon : nitrous oxide
Source: Aspergillus flavus. Organism_taxid: 5059. Gene: uaz, uox. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932
Chain: A (296 residues) CATH domain: 3.10.270.10
Bound ligand:   Het Group AZA is 76.92% similar to enzyme reactant Urate
3plm
Urate oxidase under 2.0 mpa / 20 bars pressure of equimolar xenon : nitrous oxide
Source: Aspergillus flavus. Organism_taxid: 5059. Gene: uaz, uox. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932
Chain: A (296 residues) CATH domain: 3.10.270.10
Bound ligand:   Het Group AZA is 76.92% similar to enzyme reactant Urate
3wlv
Thermostable urate oxidase from bacillus sp. Tb-90
Source: Bacillus. Organism_taxid: 36824. Strain: tb-90. Gene: uao. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (303 residues) CATH domain: 3.10.270.10
Bound ligand:   Het Group AZA is 76.92% similar to enzyme reactant Urate
4fsk
Urate oxidase-azide complex in anaerobic conditions
Source: Aspergillus flavus. Organism_taxid: 5059. Gene: uaz, uox. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932
Chain: A (295 residues) CATH domain: 3.10.270.10
4mb8
Evolutionary history and metabolic insights of ancient mamma uricases
Source: Unclassified mammalia. Organism_taxid: 1002697. Gene: phylogenetically predicted sequence for the mammalian ancestor, uox. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (285 residues) CATH domain: Unassigned
4n3m
Joint neutron/x-ray structure of urate oxidase in complex wi azaxanthine
Source: Aspergillus flavus. Organism_taxid: 5059. Gene: uaz, uox. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932
Chain: A (296 residues) CATH domain: 3.10.270.10
Bound ligand:   Het Group AZA is 66.67% similar to enzyme reactant Urate
4n9m
Joint neutron/x-ray structure of urate oxidase in complex wi hydroxyxanthine
Source: Aspergillus flavus. Organism_taxid: 5059. Gene: uaz, uox. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932
Chain: A (296 residues) CATH domain: 3.10.270.10
Bound ligand:   Het Group 8HX is 80.00% similar to enzyme reactant Urate
4n9s
High resolution x-ray structure of urate oxidase in complex hydroxyxanthine
Source: Aspergillus flavus. Organism_taxid: 5059. Gene: uaz, uox. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932
Chain: A (296 residues) CATH domain: 3.10.270.10
Bound ligand:   Het Group 8HX is 80.00% similar to enzyme reactant Urate
4n9v
High resolution x-ray structure of urate oxidase in complex azaxanthine
Source: Aspergillus flavus. Organism_taxid: 5059. Gene: uaz, uox. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932
Chain: A (296 residues) CATH domain: 3.10.270.10
Bound ligand:   Het Group AZA is 66.67% similar to enzyme reactant Urate
4op9
Urate oxidase in complex with 8-azaxanthine
Source: Aspergillus flavus. Organism_taxid: 5059. Gene: uaz, uox. Expressed in: saccharomyces cerevisiae. Expression_system_taxid: 4932
Chain: A (296 residues) CATH domain: 3.10.270.10
Bound ligand:   Het Group AZA is 76.92% similar to enzyme reactant Urate