_EC 1.5.3.1 Sarcosine oxidase. 28 PDB entries  
EC 1.-.-.- Oxidoreductases. [8,653 PDB entries]
EC 1.5.-.- Acting on the CH-NH group of donors. [619 PDB entries]
EC 1.5.3.- With oxygen as acceptor. [83 PDB entries]
EC 1.5.3.1 Sarcosine oxidase. [28 PDB entries]    
1b3m

Reaction: Sarcosine + H(2)O + O(2) = glycine + formaldehyde + H(2)O(2).
 


Sarcosine
+ H(2)O
+
O(2)
=
glycine
+
formaldehyde
+
H(2)O(2)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Cofactor(s): Fad.
 

FAD
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.
Comments: The flavin is both covalently and non-covalently bound in a molar ratio of 1:1.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 28 PDB entries in enzyme class E.C.1.5.3.1

  PDB code Protein
1b3m
Monomeric sarcosine oxidase from bacillus sp. B-0618
Source: Bacillus sp.. Strain: b-0618. Expressed in: escherichia coli.
Chains: A, B (385 residues) CATH domains: 3.50.50.60 3.30.9.10
Bound ligand:   Het Group FAD corresponds to enzyme cofactor FAD
1el5
Complex of monomeric sarcosine oxidase with the inhibitor dimethylglycine
Source: Bacillus sp.. Organism_taxid: 69000. Strain: b-0618. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_cell: dh1 cells
Chains: A, B (385 residues) CATH domains: 3.50.50.60 3.30.9.10
Bound ligands:   Het Group DMG is 85.71% similar to enzyme reactant Sarcosine
  Het Group FAD corresponds to enzyme cofactor FAD
1el7
Complex of monomeric sarcosine oxidase with the inhibitor [methytelluro]acetate
Source: Bacillus sp.. Organism_taxid: 69000. Strain: b-0618. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_cell: dh1 cells
Chains: A, B (385 residues) CATH domains: 3.50.50.60 3.30.9.10
Bound ligands:   Het Group MTD is 57.14% similar to enzyme product Glycine
  Het Group FAD corresponds to enzyme cofactor FAD
1el8
Complex of monomeric sarcosine oxidase with the inhibitor [methylseleno]cetate
Source: Bacillus sp.. Organism_taxid: 69000. Strain: b-0618. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_cell: dh1 cells
Chains: A, B (385 residues) CATH domains: 3.50.50.60 3.30.9.10
Bound ligands:   Het Group MSF is 57.14% similar to enzyme product Glycine
  Het Group FAD corresponds to enzyme cofactor FAD
1el9
Complex of monomeric sarcosine oxidase with the inhibitor [methylthio]acetate
Source: Bacillus sp.. Organism_taxid: 69000. Strain: b-0618. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_cell: dh1 cells
Chains: A, B (385 residues) CATH domains: 3.50.50.60 3.30.9.10
Bound ligands:   Het Group MTG is 57.14% similar to enzyme product Glycine
  Het Group FAD corresponds to enzyme cofactor FAD
1eli
Complex of monomeric sarcosine oxidase with the inhibitor py carboxylate
Source: Bacillus sp.. Organism_taxid: 69000. Strain: b-0618. Expressed in: escherichia coli. Expression_system_taxid: 562. Expression_system_cell: dh1 cells
Chains: A, B (385 residues) CATH domains: 3.50.50.60 3.30.9.10
Bound ligands:   Het Group PYC is 75.00% similar to enzyme reactant Sarcosine
  Het Group FAD corresponds to enzyme cofactor FAD
1l9c
Role of histidine 269 in catalysis by monomeric sarcosine ox
Source: Bacillus sp.. Organism_taxid: 69000. Strain: b-0618. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (385 residues) CATH domains: 3.50.50.60 3.30.9.10
Bound ligand:   Het Group FAD corresponds to enzyme cofactor FAD
1l9d
Role of histidine 269 in catalysis by monomeric sarcosine ox
Source: Bacillus sp.. Organism_taxid: 69000. Strain: b-0618. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (385 residues) CATH domains: 3.50.50.60 3.30.9.10
Bound ligands:   Het Group PYC is 75.00% similar to enzyme reactant Sarcosine
  Het Group FAD corresponds to enzyme cofactor FAD
1l9e
Role of histidine 269 in catalysis by monomeric sarcosine ox
Source: Bacillus sp.. Organism_taxid: 69000. Strain: b-0618. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (385 residues) CATH domains: 3.50.50.60 3.30.9.10
Bound ligands:   Het Group IMD is 57.14% similar to enzyme reactant Sarcosine
  Het Group FAD corresponds to enzyme cofactor FAD
1l9f
Monomeric sarcosine oxidase: structure of a covalently flavinylated amine oxidizing enzyme
Source: Bacillus sp.. Bacteria. Strain: b-0618. Expressed in: escherichia coli.
Chains: A, B (387 residues) CATH domains: 3.50.50.60 3.30.9.10
Bound ligand:   Het Group FAD corresponds to enzyme cofactor FAD
1vrq
Crystal structure of heterotetrameric sarcosine oxidase from corynebacterium sp. U-96 in complex with folinic acid
Source: Corynebacterium sp.. Organism_taxid: 31944. Strain: u-96. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: B (402 residues) CATH domains: 3.50.50.60 3.30.9.10
Bound ligands:   Het Group DMG is 85.71% similar to enzyme reactant Sarcosine
  Het Group FAD corresponds to enzyme cofactor FAD
1x31
Crystal structure of heterotetrameric sarcosine oxidase from corynebacterium sp. U-96
Source: Corynebacterium sp.. Organism_taxid: 31944. Strain: u-96. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: B (402 residues) CATH domains: 3.50.50.60 3.30.9.10
Bound ligands:   Het Group DMG is 85.71% similar to enzyme reactant Sarcosine
  Het Group FAD corresponds to enzyme cofactor FAD
1zov
Crystal structure of monomeric sarcosine oxidase from bacill 129
Source: Bacillus sp.. Organism_taxid: 1419. Strain: ns-129
Chains: A, B (381 residues) CATH domains: 3.50.50.60 3.30.9.10
Bound ligand:   Het Group FAD corresponds to enzyme cofactor FAD
2a89
Monomeric sarcosine oxidase: structure of a covalently flavi amine oxidizing enzyme
Source: Bacillus sp.. Organism_taxid: 69000. Strain: b-0618. Gene: soxa, sox. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (385 residues) CATH domains: 3.50.50.60 3.30.9.10
Bound ligand:   Het Group FCG is 92.98% similar to enzyme cofactor FAD
2gb0
Monomeric sarcosine oxidase: structure of a covalently flavi amine oxidizing enzyme
Source: Bacillus sp.. Organism_taxid: 69000. Strain: b-0618. Gene: soxa, sox. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (387 residues) CATH domains: 3.50.50.60 3.30.9.10
Bound ligand:   Het Group FAD corresponds to enzyme cofactor FAD
2gf3
Structure of the complex of monomeric sarcosine with its sub analogue inhibitor 2-furoic acid at 1.3 a resolution.
Source: Bacillus sp.. Organism_taxid: 1409. Gene: soxa, sox. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (385 residues) CATH domains: 3.50.50.60 3.30.9.10
Bound ligands:   Het Group FOA is 44.44% similar to enzyme product Glycine
  Het Group FAD corresponds to enzyme cofactor FAD
3ad7
Heterotetrameric sarcosine oxidase from corynebacterium sp. Complex with methylthio acetate
Source: Corynebacterium sp. U-96. Organism_taxid: 31944. Gene: soxa. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: soxb. Gene: soxg. Gene: soxd.
Chain: B (404 residues) CATH domains: 3.50.50.60 3.30.9.10
Bound ligands:   Het Group MTG is 57.14% similar to enzyme product Glycine
  Het Group FAD corresponds to enzyme cofactor FAD
3ad8
Heterotetrameric sarcosine oxidase from corynebacterium sp. Complex with pyrrole 2-carboxylate
Source: Corynebacterium sp. U-96. Organism_taxid: 31944. Gene: soxa. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: soxb. Gene: soxg. Gene: soxd.
Chain: B (404 residues) CATH domains: 3.50.50.60 3.30.9.10
Bound ligands:   Het Group PYC is 75.00% similar to enzyme reactant Sarcosine
  Het Group FAD corresponds to enzyme cofactor FAD
3ad9
Heterotetrameric sarcosine oxidase from corynebacterium sp. Sarcosine-reduced form
Source: Corynebacterium sp. U-96. Organism_taxid: 31944. Gene: soxa. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: soxb. Gene: soxg. Gene: soxd.
Chain: B (397 residues) CATH domains: 3.50.50.60 3.30.9.10
Bound ligand:   Het Group FAD corresponds to enzyme cofactor FAD
3ada
Heterotetrameric sarcosine oxidase from corynebacterium sp. Complex with sulfite
Source: Corynebacterium sp. U-96. Organism_taxid: 31944. Gene: soxa. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: soxb. Gene: soxg. Gene: soxd.
Chain: B (397 residues) CATH domains: 3.50.50.60 3.30.9.10
Bound ligand:   Het Group FAD corresponds to enzyme cofactor FAD
3bhf
Crystal structure of r49k mutant of monomeric sarcosine oxidase crystallized in peg as precipitant
Source: Bacillus sp.. Organism_taxid: 1409. Gene: soxa, sox. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (381 residues) CATH domains: 3.50.50.60 3.30.9.10
Bound ligand:   Het Group FAD corresponds to enzyme cofactor FAD
3bhk
Crystal structure of r49k mutant of monomeric sarcosine oxid crystallized in phosphate as precipitant
Source: Bacillus sp.. Organism_taxid: 69000. Strain: b-0618. Gene: soxa, sox. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (385 residues) CATH domains: 3.50.50.60 3.30.9.10
Bound ligand:   Het Group FAD corresponds to enzyme cofactor FAD
3m0o
Crystal structure of the lys265met mutant of monomeric sarco oxidase
Source: Bacillus sp.. Organism_taxid: 69000. Strain: b-0618. Gene: sox, soxa. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (385 residues) CATH domains: 3.50.50.60 3.30.9.10
Bound ligand:   Het Group FAD corresponds to enzyme cofactor FAD
3m12
Crystal structure of the lys265arg phosphate-crytsallized mu monomeric sarcosine oxidase
Source: Bacillus sp. B-0618. Organism_taxid: 69000. Strain: b-0618. Gene: soxa, sox. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (381 residues) CATH domains: 3.50.50.60 3.30.9.10
Bound ligand:   Het Group FAD corresponds to enzyme cofactor FAD
3m13
Crystal structure of the lys265arg peg-crystallized mutant o monomeric sarcosine oxidase
Source: Bacillus sp.. Organism_taxid: 69000. Strain: b-0618. Gene: soxa, sox. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D (381 residues) CATH domains: 3.50.50.60 3.30.9.10
Bound ligand:   Het Group FAD corresponds to enzyme cofactor FAD
3qse
Crystal structure for the complex of substrate-reduced msox sarcosine
Source: Bacillus sp.. Organism_taxid: 69000. Strain: b-0618. Gene: soxa, sox. Expressed in: escherichia coli. Expression_system_taxid: 536056.
Chains: A, B (385 residues) CATH domains: 3.50.50.60 3.30.9.10
Bound ligands:   Het Group SAR corresponds to enzyme reactant Sarcosine
  Het Group FAD corresponds to enzyme cofactor FAD
3qsm
Crystal structure for the msox.Chloride binary complex
Source: Bacillus sp.. Organism_taxid: 69000. Strain: b-0618. Gene: soxa, sox. Expressed in: escherichia coli. Expression_system_taxid: 536056.
Chains: A, B (387 residues) CATH domains: 3.50.50.60 3.30.9.10
Bound ligand:   Het Group FAD corresponds to enzyme cofactor FAD
3qss
Crystal structure for the msox.Chloride.Mta ternary complex
Source: Bacillus sp.. Organism_taxid: 69000. Strain: b-0618. Gene: soxa, sox. Expressed in: escherichia coli. Expression_system_taxid: 536056.
Chains: A, B (383 residues) CATH domains: 3.50.50.60 3.30.9.10
Bound ligands:   Het Group MTG is 57.14% similar to enzyme product Glycine
  Het Group FAD corresponds to enzyme cofactor FAD