_EC 1.4.1.3 Glutamate dehydrogenase (NAD(P)(+)). 17 PDB entries  
EC 1.-.-.- Oxidoreductases. [7,297 PDB entries]
EC 1.4.-.- Acting on the CH-NH(2) group of donors. [294 PDB entries]
EC 1.4.1.- With NAD(+) or NADP(+) as acceptor. [55 PDB entries]
EC 1.4.1.3 Glutamate dehydrogenase (NAD(P)(+)). [17 PDB entries]    
1b26

Reaction: L-glutamate + H(2)O + NAD(P)(+) = 2-oxoglutarate + NH(3) + NAD(P)H.
 


L-glutamate
+ H(2)O
+
NAD(P)(+)
=
2-oxoglutarate
+ NH(3)
+
NAD(P)H
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): Glutamic dehydrogenase.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 17 PDB entries in enzyme class E.C.1.4.1.3

  PDB code Protein
1b26
Glutamate dehydrogenase
Source: Thermotoga maritima. Organism_taxid: 2336. Cellular_location: cytoplasm. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B, C, D, E, F (409 residues) CATH domains: 3.40.50.10860 3.40.50.720
1b3b
Thermotoga maritima glutamate dehydrogenase mutant n97d, g376k
Source: Thermotoga maritima. Organism_taxid: 2336. Cellular_location: cytoplasm. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B, C, D, E, F (409 residues) CATH domains: 3.40.50.10860 3.40.50.720
1ch6
Crystal structure of bovine liver glutamate dehydrogenase complexed with gtp, nadh, and l-glutamic acid
Source: Bos taurus. Bovine. Organ: liver. Organelle: mitochondria. Cellular_location: inner mitochondrial matrix
Chains: A, B, C, D, E, F (496 residues) CATH domains: 3.40.50.10860 3.40.50.720 1.10.287.140
Bound ligands:   Het Group GLU corresponds to enzyme reactant L-glutamate
  Het Group NAD is 91.00% similar to enzyme reactant NADP(+)
1euz
Glutamate dehydrogenase from thermococcus profundus in the u state
Source: Thermococcus profundus. Organism_taxid: 49899. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D, E, F (416 residues) CATH domains: 3.40.50.10860 3.40.50.720
1gtm
Structure of glutamate dehydrogenase
Source: Pyrococcus furiosus. Organism_taxid: 186497. Strain: dsm 3638
Chains: A, B, C (417 residues) CATH domains: 3.40.50.10860 3.40.50.720
1hwx
Crystal structure of bovine liver glutamate dehydrogenase co with gtp, nadh, and l-glutamic acid
Source: Bos taurus. Cattle. Organism_taxid: 9913. Organ: liver. Organelle: mitochondria. Cellular_location: inner mitochondrial matrix
Chains: A, B, C, D, E, F (501 residues) CATH domains: 1.10.287.140 3.40.50.10860 3.40.50.720
Bound ligands:   Het Group GLU corresponds to enzyme reactant L-glutamate
  Het Group NAI is 91.00% similar to enzyme reactant NADP(+)
1hwy
Bovine glutamate dehydrogenase complexed with NAD and 2-oxog
Source: Bos taurus. Cattle. Organism_taxid: 9913. Organ: liver. Organelle: mitochondria. Cellular_location: inner mitochondrial matrix
Chains: A, B, C, D, E, F (501 residues) CATH domains: 1.10.287.140 3.40.50.10860 3.40.50.720
Bound ligands:   Het Group NAD is 91.67% similar to enzyme reactant NADP(+)
  Het Group AKG corresponds to enzyme product 2-oxoglutarate
1l1f
Structure of human glutamate dehydrogenase-apo form
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D, E, F (496 residues) CATH domains: 3.40.50.10860 3.40.50.720 1.10.287.140
1nqt
Crystal structure of bovine glutamate dehydrogenase-adp complex
Source: Bos taurus. Cattle. Organism_taxid: 9913. Organ: liver. Organelle: mitochondria
Chains: A, B, C, D, E, F, G, H, I, J, K, L (496 residues) CATH domains: 3.40.50.10860 3.40.50.720 1.10.287.140
Bound ligand:   Het Group ADP is 56.00% similar to enzyme reactant NADP(+)
1nr1
Crystal structure of the r463a mutant of human glutamate dehydrogenase
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D, E, F (496 residues) CATH domains: 3.40.50.10860 3.40.50.720 1.10.287.140
2tmg
Thermotoga maritima glutamate dehydrogenase mutant s128r, t158e, n117r, s160e
Source: Thermotoga maritima. Organism_taxid: 2336. Cellular_location: cytoplasm. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B, C, D, E, F (408 residues) CATH domains: 3.40.50.10860 3.40.50.720
3etd
Structure of glutamate dehydrogenase complexed with bithionol
Source: Bos taurus. Bovine,cow. Organism_taxid: 9913. Tissue: liver
Chains: A, B, C, D, E, F (501 residues) CATH domains: 1.10.287.140 3.40.50.10860 3.40.50.720
Bound ligands:   Het Group GLU is 90.00% similar to enzyme reactant L-glutamate
  Het Group NDP corresponds to enzyme reactant NADP(+)
3ete
Crystal structure of bovine glutamate dehydrogenase complexed with hexachlorophene
Source: Bos taurus. Organism_taxid: 9913. Tissue: liver
Chains: A, B, C, D, E, F (495 residues) CATH domains: 1.10.287.140 3.40.50.10860 3.40.50.720
Bound ligands:   Het Group GLU is 90.00% similar to enzyme reactant L-glutamate
  Het Group NDP corresponds to enzyme reactant NADP(+)
3etg
Glutamate dehydrogenase complexed with gw5074
Source: Bos taurus. Organism_taxid: 9913. Tissue: liver
Chains: A, B, C, D, E, F (501 residues) CATH domains: 1.10.287.140 3.40.50.10860 3.40.50.720
Bound ligands:   Het Group GLU is 90.00% similar to enzyme reactant L-glutamate
  Het Group NDP corresponds to enzyme reactant NADP(+)
3mvq
Bovine glutamate dehydrogenase complexed with zinc
Source: Bos taurus. Bovine. Organism_taxid: 9913. Other_details: liver
Chains: A, B, C, D, E, F (495 residues) CATH domains: 1.10.287.140 3.40.50.10860 3.40.50.720
Bound ligands:   Het Group GLU corresponds to enzyme reactant L-glutamate
  Het Group NDP corresponds to enzyme reactant NADP(+)
3mw9
Bovine glutamate dehydrogenase complexed with nadh, gtp, glu
Source: Bos taurus. Bovine,cow,domestic cattle,domestic cow. Organism_taxid: 9913. Organ: liver
Chains: A, B, C, D, E, F (501 residues) CATH domains: 1.10.287.140 3.40.50.10860 3.40.50.720
Bound ligands:   Het Group GLU corresponds to enzyme reactant L-glutamate
  Het Group NAI is 91.67% similar to enzyme reactant NADP(+)
3qmu
Bovine glutamate dehydrogenase complexed with epicatechin-3- (ecg)
Source: Bos taurus. Bovine,cow,domestic cattle,domestic cow. Organism_taxid: 9913
Chains: A, B, C, D, E, F, G, H, I, J, K, L (496 residues) CATH domains: 1.10.287.140 3.40.50.10860 3.40.50.720
Bound ligand:   Het Group NDP corresponds to enzyme reactant NADP(+)