_EC 1.3.1.94 Polyprenol reductase. 0 PDB entries  
EC 1.-.-.- Oxidoreductases. [8,663 PDB entries]
EC 1.3.-.- Acting on the CH-CH group of donors. [662 PDB entries]
EC 1.3.1.- With NAD(+) or NADP(+) as acceptor. [343 PDB entries]
EC 1.3.1.94 Polyprenol reductase. [-]    

Reaction: Ditrans,polycis-dolichol + NADP(+) = ditrans,polycis-polyprenol + Nadph.
 

Ditrans,polycis-dolichol
+
NADP(+)
= ditrans,polycis-polyprenol
+
NADPH
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Comments: The reaction occurs in the reverse direction with reduction of the terminal double bond next to the alcohol group. Isolated from human fetal brain tissue but present in all eukaryotes. In mammalian cells dolichols are predominantly 18-21 isoprene units in length.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are no PDB entries in enzyme class E.C.1.3.1.94