_EC 3-oxo-5-alpha-steroid 4-dehydrogenase (NADP(+)). 0 PDB entries  
EC 1.-.-.- Oxidoreductases. [9,199 PDB entries]
EC 1.3.-.- Acting on the CH-CH group of donors. [688 PDB entries]
EC 1.3.1.- With NAD(+) or NADP(+) as acceptor. [363 PDB entries]
EC 3-oxo-5-alpha-steroid 4-dehydrogenase (NADP(+)). [-]    

Reaction: A 3-oxo-5-alpha-steroid + NADP(+) = a 3-oxo-Delta(4)-steroid + nadph.

Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): 3-oxo-5-alpha-steroid 4-dehydrogenase. Cholestenone 5-alpha-reductase.
Comments: The enzyme catalyzes the conversion of assorted 3-oxo-Delta(4) steroids into their corresponding 5-alpha form. Substrates for the mammalian enzyme include testosterone, progesterone, and corticosterone. Substrates for the plant enzyme are brassinosteroids such as campest- 4-en-3-one and (22-alpha)-hydroxy-campest-4-en-3-one. Cf. Ec Formerly Ec and Ec
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are no PDB entries in enzyme class E.C.