_EC 1.14.99.15 4-methoxybenzoate monooxygenase (O-demethylating). 2 PDB entries  
EC 1.-.-.- Oxidoreductases. [9,090 PDB entries]
EC 1.14.-.- Acting on paired donors, with incorporation or reduction of molecu [1,534 PDB entries]
EC 1.14.99.- Miscellaneous (requires further characterization). [155 PDB entries]
EC 1.14.99.15 4-methoxybenzoate monooxygenase (O-demethylating). [2 PDB entries]    
2fr7

Reaction: 4-methoxybenzoate + AH(2) + O(2) = 4-hydroxybenzoate + formaldehyde + A + H(2)O.
 


4-methoxybenzoate
+ AH(2)
+
O(2)
=
4-hydroxybenzoate
+
formaldehyde
+
+ H(2)O
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): 4-methoxybenzoate O-demethylase.
Cofactor(s): Flavoprotein; Iron-sulfur.
 
Flavoprotein

Iron-sulfur
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.
Comments: The bacterial enzyme consists of a ferredoxin-type protein and an iron-sulfur flavoprotein (FMN). Also acts on 4-ethoxybenzoate, N-methyl-4-aminobenzoate and toluate. The fungal enzyme acts best on veratrate.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 2 PDB entries in enzyme class E.C.1.14.99.15

  PDB code Protein
2fr7
Crystal structure of cytochrome p450 cyp199a2
Source: Rhodopseudomonas palustris. Organism_taxid: 258594. Strain: cga009. Gene: cyp199a2. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (397 residues) CATH domain: 1.10.630.10
4dnj
The crystal structures of 4-methoxybenzoate bound cyp199a2
Source: Rhodopseudomonas palustris. Organism_taxid: 258594. Strain: cga009. Gene: rpa1871. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (399 residues) CATH domain: 1.10.630.10