_EC 1.14.15.4 Steroid 11-beta-monooxygenase. 2 PDB entries  
EC 1.-.-.- Oxidoreductases. [8,663 PDB entries]
EC 1.14.-.- Acting on paired donors, with incorporation or reduction of molecu [1,436 PDB entries]
EC 1.14.15.- With a reduced iron-sulfur protein as one donor, and incorporatio [132 PDB entries]
EC 1.14.15.4 Steroid 11-beta-monooxygenase. [2 PDB entries]    
4dvq

Reaction: A steroid + reduced adrenodoxin + O(2) = an 11-beta-hydroxysteroid + oxidized adrenodoxin + H(2)O.
 

steroid
+ reduced adrenodoxin
+
O(2)
= 11-beta-hydroxysteroid
+ oxidized adrenodoxin
+ H(2)O
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): Cytochrome p450 XIB1. Steroid 11-beta-hydroxylase. Steroid 11-beta/18-hydroxylase.
Cofactor(s): Heme-thiolate.
Comments: Also hydroxylates steroids at the 18-position, and converts 18-hydroxycorticosterone into aldosterone. Formerly Ec 1.14.1.6 and Ec 1.99.1.7.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 2 PDB entries in enzyme class E.C.1.14.15.4

  PDB code Protein
4dvq
Structure of human aldosterone synthase, cyp11b2, in complex deoxycorticosterone
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: aldosterone synthase, cyp11b2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D, E, F, G, H, I, J, K, L (463 residues) CATH domain: 1.10.630.10
4fdh
Structure of human aldosterone synthase, cyp11b2, in complex fadrozole
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: aldosterone synthase, cyp11b2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D, E, F, G, H, I, J, K, L (463 residues) CATH domain: 1.10.630.10