_EC 1.14.13.39 Nitric-oxide synthase (Nadph dependent). 354 PDB entries  
EC 1.-.-.- Oxidoreductases. [8,609 PDB entries]
EC 1.14.-.- Acting on paired donors, with incorporation or reduction of molecu [1,433 PDB entries]
EC 1.14.13.- With Nadh or nadph as one donor, and incorporation of one atom of [655 PDB entries]
EC 1.14.13.39 Nitric-oxide synthase (Nadph dependent). [354 PDB entries]    
1b8q

Reaction: 2 L-arginine + 3 Nadph + 4 O(2) = 2 L-citrulline + 2 nitric oxide + 3 NADP(+) + 4 H(2)O.
 


2 × L-arginine
+
3 × NADPH
+
4 × O(2)
=
2 × L-citrulline
+
2 × nitric oxide
+
3 × NADP(+)
+ 4 × H(2)O
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): Endothelium-derived relaxation factor-forming enzyme. Endothelium-derived relaxing factor synthase. NADPH-diaphorase. Nitric-oxide synthetase. No synthase.
Comments: This eukaryotic enzyme, which is found in plants and animals, consists of oxygenase and reductase domains that are linked via a regulatory calmodulin-binding domain. Upon calcium-induced calmodulin binding, the reductase and oxygenase domains form a complex, allowing electrons to flow from Nadph via fad and Fmn to the active center. May produce superoxide under certain conditions. Cf. Ec 1.14.13.165.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 354 PDB entries in enzyme class E.C.1.14.13.39

  PDB code Protein
1b8q
Solution structure of the extended neuronal nitric oxide synthase pdz domain complexed with an associated peptide
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes
Chain: A (127 residues) CATH domain: 2.30.42.10
Bound ligand:   Het Group LYS is 50.00% similar to enzyme reactant L-arginine
1cmi
Structure of the human pin/lc8 dimer with a bound peptide
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693. Synthetic: yes
Chain: A (85 residues) CATH domain: 3.30.740.10
1d0c
Bovine endothelial nitric oxide synthase heme domain complex bromo-7-nitroindazole (h4b free)
Source: Bos taurus. Cattle. Organism_taxid: 9913. Cell: endothelial cells. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (416 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
1d0o
Bovine endothelial nitric oxide synthase heme domain complex bromo-7-nitroindazole (h4b present)
Source: Bos taurus. Cattle. Organism_taxid: 9913. Cell: endothelial cells. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (416 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
1d1v
Bovine endothelial nitric oxide synthase heme domain complex ethyl-n-phenyl-isothiourea (h4b bound)
Source: Bos taurus. Cattle. Organism_taxid: 9913. Cell: endothelial cells. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (416 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group PTU is 50.00% similar to enzyme reactant L-arginine
1d1w
Bovine endothelial nitric oxide synthase heme domain complex aminothiazoline (h4b bound)
Source: Bos taurus. Cattle. Organism_taxid: 9913. Cell: endothelial cells. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (416 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
1d1x
Bovine endothelial nitric oxide synthase heme domain complex 4-pbitu (h4b bound)
Source: Bos taurus. Cattle. Organism_taxid: 9913. Cell: endothelial cells. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (416 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
1d1y
Bovine endothelial nitric oxide synthase heme domain complex 3-pbitu (h4b free)
Source: Bos taurus. Cattle. Organism_taxid: 9913. Cell: endothelial cells. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (416 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
1dd7
Murine inducible nitric oxide synthase oxygenase domain (delta 114) (n-[(1,3-benzodioxol-5-yl)methyl]-1-[2-(1h- imidazol-1-yl)pyrimidin-4-yl]-4-(methoxycarbonyl)- piperazine-2-acetamide complex
Source: Mus musculus. House mouse. Organism_taxid: 10090. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (295 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
1df1
Murine inosoxy dimer with isothiourea bound in the active si
Source: Mus musculus. House mouse. Organism_taxid: 10090. Cell: macrophage. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (420 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
1dm6
Bovine endothelial nitric oxide synthase heme domain complex (4-chlorophenyl)-n'-hydroxyguanidine (h4b free)
Source: Bos taurus. Cattle. Organism_taxid: 9913. Cell: endothelial. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (416 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group PH3 is 60.00% similar to enzyme reactant L-arginine
1dm7
Bovine endothelial nitric oxide synthase heme domain complex homoarginine (h4b free)
Source: Bos taurus. Cattle. Organism_taxid: 9913. Cell: endothelial. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (416 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group HRG is 56.25% similar to enzyme reactant L-arginine
1dm8
Bovine endothelial nitric oxide synthase heme domain complex 2,4-triazole-carboxamidine (h4b bound)
Source: Bos taurus. Cattle. Organism_taxid: 9913. Cell: endothelial. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (416 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
1dmi
Bovine endothelial nitric oxide synthase heme domain complex 6s-h4b
Source: Bos taurus. Cattle. Organism_taxid: 9913. Cell: endothelial. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (416 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
1dmj
Bovine endothelial nitric oxide synthase heme domain complex 6-cyclic-tetrahydropteridine
Source: Bos taurus. Cattle. Organism_taxid: 9913. Cell: endothelial. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (416 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
1dmk
Bovine endothelial nitric oxide synthase heme domain complex amino-6-phenyl-tetrahydropteridine
Source: Bos taurus. Cattle. Organism_taxid: 9913. Cell: endothelial. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (416 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
1dwv
Murine inducible nitric oxide synthase oxygenase dimer n-hydroxyarginine and 4-amino tetrahydrobiopterin
Source: Mus musculus. Mouse. Organism_taxid: 10090. Cell: macrophage. Plasmid: pcwori. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (420 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group HAR is 92.00% similar to enzyme reactant L-arginine
1dww
Murine inducible nitric oxide synthase oxygenase dimer n-hydroxyarginine and dihydrobiopterin
Source: Mus musculus. Mouse. Organism_taxid: 10090. Cell: macrophage. Plasmid: pcwori. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (420 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group HAR is 92.00% similar to enzyme reactant L-arginine
1dwx
Murine inducible nitric oxide synthase oxygenase dimer n-hydroxyarginine and tetrahydrobiopterin
Source: Mus musculus. Mouse. Organism_taxid: 10090. Cell: macrophage. Plasmid: pcwori. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (414 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group HAR is 92.00% similar to enzyme reactant L-arginine
1ed4
Bovine endothelial nitric oxide synthase heme domain complex ipitu (h4b free)
Source: Bos taurus. Cattle. Organism_taxid: 9913. Cell: endothelial. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (416 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
1ed5
Bovine endothelial nitric oxide synthase heme domain complex nna(h4b free)
Source: Bos taurus. Cattle. Organism_taxid: 9913. Cell: endothelial. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (416 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group NRG is 80.00% similar to enzyme reactant L-arginine
1ed6
Bovine endothelial nitric oxide synthase heme domain complex nio (h4b free)
Source: Bos taurus. Cattle. Organism_taxid: 9913. Cell: endothelial. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (416 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group ILO is 84.62% similar to enzyme reactant L-arginine
1f20
Crystal structure of rat neuronal nitric-oxide synthase fad/ domain at 1.9a resolution.
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (435 residues) CATH domains: 3.40.50.80 1.20.990.10 2.40.30.10
Bound ligand:   Het Group NAP corresponds to enzyme reactant NADPH
1foi
Bovine endothelial nitric oxide synthase heme domain complex 1400w(h4b-free)
Source: Bos taurus. Cattle. Organism_taxid: 9913. Cell: endothelial cells. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (416 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group 14W is 53.33% similar to enzyme reactant L-arginine
1foj
Bovine endothelial nitric oxide synthase heme domain complex nitroindazole-2-carboxamidine (h4b present)
Source: Bos taurus. Cattle. Organism_taxid: 9913. Cell: endothelial cells. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (416 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group 7I2 is 58.82% similar to enzyme reactant L-arginine
1fol
Reduced bovine endothelial nitric oxide synthase heme domain with l-arg(h4b-free)
Source: Bos taurus. Cattle. Organism_taxid: 9913. Cell: endothelial cells. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (416 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group ARG corresponds to enzyme reactant L-arginine
1foo
Bovine endothelial nitric oxide synthase heme domain complex arg and no(h4b-free)
Source: Bos taurus. Cattle. Organism_taxid: 9913. Cell: endothelial cells. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (416 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligands:   Het Group ARG corresponds to enzyme reactant L-arginine
  Het Group NO corresponds to enzyme product Nitric
1fop
Bovine endothelial nitric oxide synthase heme domain complex arg and no(h4b-bound)
Source: Bos taurus. Cattle. Organism_taxid: 9913. Cell: endothelial cells. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (416 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligands:   Het Group ARG corresponds to enzyme reactant L-arginine
  Het Group NO corresponds to enzyme product Nitric
1i83
Bovine endothelial nitric oxide synthase heme domain complex n1,n14-bis((s-methyl)isothioureido)tetradecane (h4b free)
Source: Bos taurus. Cattle. Organism_taxid: 9913. Cell_line: epithelial cells. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (416 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group NTU is 50.00% similar to enzyme reactant L-arginine
1jwj
Murine inducible nitric oxide synthase oxygenase dimer (delt w457f mutation at tetrahydrobiopterin binding site
Source: Mus musculus. House mouse. Organism_taxid: 10090. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (412 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
1jwk
Murine inducible nitric oxide synthase oxygenase dimer (delt w457a mutation at tetrahydrobiopterin binding site
Source: Mus musculus. House mouse. Organism_taxid: 10090. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (413 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
1k2r
Structure of rat brain nnos heme domain complexed with ng- nitro-l-arginine
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Gene: brain. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group NRG is 80.00% similar to enzyme reactant L-arginine
1k2s
Structure of rat brain nnos heme domain complexed with ng- allyl-l-arginine
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Gene: brain. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group ARV is 80.00% similar to enzyme reactant L-arginine
1k2t
Structure of rat brain nnos heme domain complexed with s- ethyl-n-phenyl-isothiourea
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Gene: brain. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group PTU is 50.00% similar to enzyme reactant L-arginine
1k2u
Structure of rat brain nnos heme domain complexed with s- ethyl-n-[4-(trifluoromethyl)phenyl] isothiourea
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Gene: brain. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group TFM is 40.00% similar to enzyme reactant L-arginine
1lzx
Rat neuronal nos heme domain with ng-hydroxy-l-arginine boun
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Organ: brain. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group HAR is 92.00% similar to enzyme reactant L-arginine
1lzz
Rat neuronal nos heme domain with n-isopropyl-n'-hydroxyguan bound
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Organ: brain. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group IHG is 42.00% similar to enzyme reactant L-arginine
1m00
Rat neuronal nos heme domain with n-butyl-n'-hydroxyguanidin
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Organ: brain. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group BHH is 61.00% similar to enzyme reactant L-arginine
1m8d
Inducible nitric oxide synthase with chlorzoxazone bound
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: inos. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (416 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group CLW is 53.33% similar to enzyme product citrulline
1m8e
Inducible nitric oxide synthase with 7-nitroindazole bound
Source: Mus musculus. House mouse. Organism_taxid: 10090. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (412 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group 7NI is 41.18% similar to enzyme reactant L-arginine
1m8h
Inducible nitric oxide synthase with 6-nitroindazole bound
Source: Mus musculus. House mouse. Organism_taxid: 10090. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (413 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
1m8i
Inducible nitric oxide synthase with 5-nitroindazole bound
Source: Mus musculus. House mouse. Organism_taxid: 10090. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (413 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group 5NI is 41.18% similar to enzyme reactant L-arginine
1m9j
Human endothelial nitric oxide synthase with chlorzoxazone bound
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (400 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group CLW is 53.00% similar to enzyme product citrulline
1m9k
Human endothelial nitric oxide synthase with 7- nitroindazole bound
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (400 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group 7NI is 41.00% similar to enzyme reactant L-arginine
1m9m
Human endothelial nitric oxide synthase with 6- nitroindazole bound
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (400 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
1m9q
Human endothelial nitric oxide synthase with 5- nitroindazole bound
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (400 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group 5NI is 41.00% similar to enzyme reactant L-arginine
1m9r
Human endothelial nitric oxide synthase with 3-bromo-7- nitroindazole bound
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (400 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
1m9t
Inducible nitric oxide synthase with 3-bromo-7-nitroindazole
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: inos. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (413 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
1mmv
Rat neuronal nos heme domain with ng-propyl-l-arginine bound
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Organ: brain. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group 3AR is 80.00% similar to enzyme reactant L-arginine
1mmw
Rat neuronal nos heme domain with vinyl-l-nio bound
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Organ: brain. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group VIO is 73.00% similar to enzyme reactant L-arginine
1n2n
Crystal structure of cyanide complex of the oxygenase domain inducible nitric oxide synthase.
Source: Mus musculus. House mouse. Organism_taxid: 10090. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (419 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group ARG is 91.67% similar to enzyme reactant L-arginine
1niw
Crystal structure of endothelial nitric oxide synthase peptide bound to calmodulin
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: the peptide was chemically synthesized. The sequence of the peptide occurs naturally in homo sapiens (human).
Chains: B, D, F, H (19 residues)
1noc
Murine inducible nitric oxide synthase oxygenase domain (delta 114) complexed with type i e. Coli chloramphenicol acetyl transferase and imidazole
Source: Mus musculus. House mouse. Organism_taxid: 10090. Cell: macrophage. Expressed in: escherichia coli. Expression_system_taxid: 562. Escherichia coli. Organism_taxid: 562
Chain: A (372 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group IMD is 41.00% similar to enzyme reactant L-arginine
1nod
Murine inducible nitric oxide synthase oxygenase dimer (delt tetrahydrobiopterin and substrate l-arginine
Source: Mus musculus. House mouse. Organism_taxid: 10090. Cell: macrophage. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (414 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group ARG corresponds to enzyme reactant L-arginine
1nos
Murine inducible nitric oxide synthase oxygenase domain (delta 114), imidazole complex
Source: Mus musculus. House mouse. Organism_taxid: 10090. Cell: macrophage. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (323 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group IMD is 41.00% similar to enzyme reactant L-arginine
1nse
Bovine endothelial nitric oxide synthase
Source: Bos taurus. Cattle. Organism_taxid: 9913. Cell: endothelial. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chains: A, B (416 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
1nsi
Human inducible nitric oxide synthase, zn-bound, l-arg compl
Source: Homo sapiens. Human. Organism_taxid: 9606. Cell: adenocarcinoma dld-1. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D (420 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group ARG corresponds to enzyme reactant L-arginine
1om4
Structure of rat neuronal nos heme domain with l-arginine bo
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Gene: nos1 or bnos. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group ARG corresponds to enzyme reactant L-arginine
1om5
Structure of rat neuronal nos heme domain with 3-bromo-7- nitroindazole bound
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Gene: nos1 or bnos. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
1p6h
Rat neuronal nos heme domain with l-n(omega)-nitroarginine- 2,4-l-diaminobutyric amide bound
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group DP1 is 47.00% similar to enzyme reactant L-arginine
1p6i
Rat neuronal nos heme domain with (4s)-n-(4-amino-5- [aminoethyl]aminopentyl)-n'-nitroguanidine bound
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Gene: nos1 or bnos. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group DP3 is 52.00% similar to enzyme reactant L-arginine
1p6j
Rat neuronal nos heme domain with l-n(omega)-nitroarginine- (4r)-amino-l-proline amide bound
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group DP9 is 45.00% similar to enzyme reactant L-arginine
1p6k
Rat neuronal nos d597n mutant heme domain with l-n(omega)- nitroarginine-2,4-l-diaminobutyric amide bound
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group DP1 is 47.83% similar to enzyme reactant L-arginine
1p6l
Bovine endothelial nos heme domain with l-n(omega)-nitroargi l-diaminobutyric amide bound
Source: Bos taurus. Cattle. Organism_taxid: 9913. Gene: endothelial nitric oxide synthase. Expressed in: pichia pastoris. Expression_system_taxid: 4922.
Chains: A, B (404 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group DP1 is 47.83% similar to enzyme reactant L-arginine
1p6m
Bovine endothelial nos heme domain with (4s)-n-(4-amino-5- [aminoethyl]aminopentyl)-n'-nitroguanidine bound
Source: Bos taurus. Cattle. Organism_taxid: 9913. Gene: endothelial nitric oxide synthase. Expressed in: pichia pastoris. Expression_system_taxid: 4922.
Chains: A, B (404 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group DP3 is 52.63% similar to enzyme reactant L-arginine
1p6n
Bovine endothelial nos heme domain with l-n(omega)-nitroargi amino-l-proline amide bound
Source: Bos taurus. Cattle. Organism_taxid: 9913. Gene: endothelial nitric oxide synthase. Expressed in: pichia pastoris. Expression_system_taxid: 4922.
Chains: A, B (406 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group DP9 is 45.83% similar to enzyme reactant L-arginine
1q2o
Bovine endothelial nitric oxide synthase n368d mutant heme d dimer with l-n(omega)-nitroarginine-2,4-l-diaminobutyramide
Source: Bos taurus. Cattle. Organism_taxid: 9913. Gene: nos3. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (405 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group DP1 is 47.83% similar to enzyme reactant L-arginine
1qau
Unexpected modes of pdz domain scaffolding revealed by structure of nnos-syntrophin complex
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (112 residues) CATH domain: 2.30.42.10
1qav
Unexpected modes of pdz domain scaffolding revealed by struc nnos-syntrophin complex
Source: Mus musculus. House mouse. Organism_taxid: 10090. Expressed in: escherichia coli. Expression_system_taxid: 562. Rattus norvegicus. Norway rat. Organism_taxid: 10116.
Chain: B (115 residues) CATH domain: 2.30.42.10
1qom
Murine inducible nitric oxide synthase oxygenase dimer (delta 65) with swapped n-terminal hook
Source: Mus musculus. Mouse. Organism_taxid: 10090. Cell: macrophage. Plasmid: pcwori. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (420 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
1qw4
Crystal structure of murine inducible nitric oxide synthase domain in complex with n-omega-propyl-l-arginine.
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: nos2 or inosl. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (419 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group 3AR is 80.00% similar to enzyme reactant L-arginine
1qw5
Murine inducible nitric oxide synthase oxygenase domain in c with w1400 inhibitor.
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: nos2 or inosl. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (419 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group 14W is 47.06% similar to enzyme reactant L-arginine
1qw6
Rat neuronal nitric oxide synthase oxygenase domain in compl omega-propyl-l-arg.
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Gene: nos1 or bnos. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (420 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group 3AR is 80.00% similar to enzyme reactant L-arginine
1qwc
Rat neuronal nitric oxide synthase oxygenase domain in compl w1400 inhibitor.
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Gene: nos1 or bnos. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (420 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group 14W is 47.06% similar to enzyme reactant L-arginine
1r35
Murine inducible nitric oxide synthase oxygenase dimer, tetrahydrobiopterin and 4r-fluoro-n6-ethanimidoyl-l-lysine
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: nos2, inosl. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (413 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group I58 is 44.44% similar to enzyme reactant L-arginine
1rs6
Rat neuronal nos heme domain with d-lysine-d-nitroarginine a
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Gene: brain. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group DP2 is 44.00% similar to enzyme reactant L-arginine
1rs7
Rat neuronal nos heme domain with d-phenylalanine-d-nitroarg amide bound
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Gene: brain. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group D7P is 40.74% similar to enzyme reactant L-arginine
1rs8
Bovine endothelial nos heme domain with d-lysine-d-nitroargi bound
Source: Bos taurus. Cattle. Organism_taxid: 9913. Gene: endothelial nitric oxide synthase. Expressed in: pichia pastoris. Expression_system_taxid: 4922. Into pichia genome.
Chains: A, B (406 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group DP2 is 44.00% similar to enzyme reactant L-arginine
1rs9
Bovine endothelial nos heme domain with d-phenylalanine-d- nitroarginine amide bound
Source: Bos taurus. Cattle. Organism_taxid: 9913. Gene: endothelial nitric oxide synthase. Expressed in: pichia pastoris. Expression_system_taxid: 4922. Into pichia chromosome.
Chains: A, B (406 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group D7P is 40.74% similar to enzyme reactant L-arginine
1tll
Crystal structure of rat neuronal nitric-oxide synthase reductase module at 2.3 a resolution.
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: pichia pastoris. Expression_system_taxid: 4922.
Chains: A, B (630 residues) CATH domains: 3.40.50.360 1.20.990.10 2.40.30.10 3.40.50.80
Bound ligand:   Het Group NAP corresponds to enzyme reactant NADPH
1vaf
Inducible nitric oxide synthase oxygenase domain complexed w inhibitor ar-r17477
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: nos2, inosl. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (419 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
1vag
Neuronal nitric oxide synthase oxygenase domain complexed wi inhibitor ar-r17477
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (420 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
1zvi
Rat neuronal nitric oxide synthase oxygenase domain
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (417 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
1zvl
Rat neuronal nitric oxide synthase oxygenase domain complexed with natural substrate l-arg.
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (420 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group ARG corresponds to enzyme reactant L-arginine
1zzq
Rat nnos d597n mutant with l-n(omega)-nitroarginine-(4r)- amino-l-proline amide bound
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group DP9 is 45.00% similar to enzyme reactant L-arginine
1zzr
Rat nnos d597n/m336v double mutant with l-n(omega)-nitroargi amino-l-proline amide bound
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group DP9 is 45.83% similar to enzyme reactant L-arginine
1zzs
Bovine enos n368d single mutant with l-n(omega)-nitroarginin amino-l-proline amide bound
Source: Bos taurus. Cattle. Organism_taxid: 9913. Gene: nos3. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (405 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group DP9 is 45.83% similar to enzyme reactant L-arginine
1zzt
Bovine enos n368d/v106m double mutant with l-n(omega)- nitroarginine-(4r)-amino-l-proline amide bound
Source: Bos taurus. Cattle. Organism_taxid: 9913. Gene: nos3. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (405 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group DP9 is 45.00% similar to enzyme reactant L-arginine
1zzu
Rat nnos d597n/m336v double mutant with l-n(omega)-nitroargi l-diaminobutyric amide bound
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group DP1 is 47.83% similar to enzyme reactant L-arginine
2bhj
Murine ino synthase with coumarin inhibitor
Source: Mus musculus. Mouse. Organism_taxid: 10090. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (414 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
2g6h
Structure of rat nnos heme domain (bh4 bound) in the reduced form
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group ARG corresponds to enzyme reactant L-arginine
2g6i
Structure of rat nnos heme domain (bh2-bound) in the reduced form
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (409 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group ARG corresponds to enzyme reactant L-arginine
2g6j
Structure of rat nnos (l337n) heme domain (4-aminobiopterin bound) complexed with no
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (409 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligands:   Het Group ARG corresponds to enzyme reactant L-arginine
  Het Group NO corresponds to enzyme product Nitric oxide
2g6k
Structure of rat nnos heme domain (bh4 bound) complexed with no
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (409 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligands:   Het Group ARG corresponds to enzyme reactant L-arginine
  Het Group NO corresponds to enzyme product Nitric oxide
2g6l
Structure of rat nnos heme domain (bh2 bound) complexed with no
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (409 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligands:   Het Group ARG corresponds to enzyme reactant L-arginine
  Het Group NO corresponds to enzyme product Nitric oxide
2g6m
Structure of rat nnos heme domain (bh4 bound) complexed with co
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group ARG corresponds to enzyme reactant L-arginine
2g6n
Strcture of rat nnos heme domain (bh2 bound) complexed with co
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (409 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group ARG corresponds to enzyme reactant L-arginine
2g6o
Structure of bovine enos heme domain (bh4-free) complexed wi
Source: Bos taurus. Cattle. Organism_taxid: 9913. Gene: nos3. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (416 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group ARG is 64.29% similar to enzyme reactant L-arginine
2hx2
Bovine enos heme domain complexed with (4s)-n-{4-amino-5-[(2 aminoethyl)-hydroxyamino]-pentyl}-n'-nitroguanidine
Source: Bos taurus. Cattle. Organism_taxid: 9913. Gene: nos3. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (403 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group 3HX is 50.00% similar to enzyme reactant L-arginine
2hx3
Rat nnos heme domain complexed with (4s)-n-{4-amino-5-[(2-am hydroxyamino]-pentyl}-n'-nitroguanidine
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group 3HX is 50.00% similar to enzyme reactant L-arginine
2hx4
Rat nnos heme domain complexed with 4-n-(nw-nitro-l-argininy 4-hydroxyamino-l-proline amide
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group 4HX is 44.00% similar to enzyme reactant L-arginine
2ll6
Solution nmr structure of cam bound to inos cam binding doma
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: calm1, calm, cam, cam1, calm2, cam2, camb, calm3, cal cam3, camc, camiii. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: nos2, nos2a.
Chain: B (17 residues)
2ll7
Solution nmr structure of cam bound to the enos cam binding peptide
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: calm1, calm, cam, cam1, calm2, cam2, camb, calm3, cal cam3, camc, camiii. Expressed in: escherichia coli. Expression_system_taxid: 562. Gene: nos3. Expression_system_taxid: 562
Chain: B (17 residues)
2mg5
Solution structure of calmodulin bound to the target peptide endothelial nitrogen oxide synthase phosphorylated at thr49
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: calm1, calm, cam, cam1, calm2, cam2, camb, calm3, cal cam3, camc, camiii. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes
Chain: B (16 residues)
2nod
Murine inducible nitric oxide synthase oxygenase dimer (delt tetrahydrobiopterin and water bound in active center
Source: Mus musculus. House mouse. Organism_taxid: 10090. Cell: macrophage. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (414 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
2nos
Murine inducible nitric oxide synthase oxygenase domain (delta 114), aminoguanidine complex
Source: Mus musculus. House mouse. Organism_taxid: 10090. Cell: macrophage. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (322 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group IMD is 41.00% similar to enzyme reactant L-arginine
2nse
Bovine endothelial nitric oxide synthase substrate complex
Source: Bos taurus. Cattle. Organism_taxid: 9913. Cell: endothelial. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chains: A, B (416 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group ARG corresponds to enzyme reactant L-arginine
2nsi
Human inducible nitric oxide synthase, zn-free, seitu complex
Source: Homo sapiens. Human. Organism_taxid: 9606. Cell: adenocarcinoma dld-1. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D (420 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
2o60
Calmodulin bound to peptide from neuronal nitric oxide synth
Source: Gallus gallus. Chicken. Organism_taxid: 9031. Gene: calm. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008. Synthetic: yes. Other_details: the peptide was chemically synthesized. This occurs naturally in mice. Peptide is acetylated at n-termin
Chain: B (21 residues)
2oro
Murine inducible nitric oxide synthase oxygenase domain (delta 114) (r)-1-(2-imidazol-1-yl-6-methyl-pyrimidin-4- yl)-pyrrolidine-2-carboxylic acid (2-benzo[1,3]dioxol-5-yl- ethyl)-amide complex
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: nos2, inosl. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (313 residues) CATH domains: 3.90.340.10 3.90.440.10
2orp
Murine inducible nitric oxide synthase oxygenase domain (delta 114) 2-[4-(2-imidazol-1-yl-6-methyl-pyrimidin-4-yl)- 1-isobutyryl-piperazin-2-yl]-n-[2-(4-methoxy-phenyl)- ethyl]-acetamide complex
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: nos2, inosl. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (304 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
2orq
Murine inducible nitric oxide synthase oxygenase domain (delta 114) 4-(imidazol-1-yl)phenol and piperonylamine complex
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: nos2, inosl. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (300 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group MSR is 41.00% similar to enzyme reactant L-arginine
2orr
Murine inducible nitric oxide synthase oxygenase domain (delta 114) 4-(benzo[1,3]dioxol-5-yloxy)-2-(4-imidazol-1- yl-phenoxy)-pyrimidine complex
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: nos2, inosl. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (291 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
2ors
Murine inducible nitric oxide synthase oxygenase domain (delta 114) 4-(benzo[1,3]dioxol-5-yloxy)-2-(4-imidazol-1- yl-phenoxy)-6-methyl-pyrimidine complex
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: nos2, inosl. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (290 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
2ort
Murine inducible nitric oxide synthase oxygenase domain (delta 114) 1-benzo[1,3]dioxol-5-ylmethyl-3s-(4-imidazol-1- yl-phenoxy)-piperidine complex
Source: Mus musculus. House mouse. Organism_taxid: 10090. Gene: nos2, inosl. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (298 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
2y37
The discovery of novel, potent and highly selective inhibitors of inducible nitric oxide synthase (inos)
Source: Mus musculus. House mouse. Organism_taxid: 10090. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (411 residues) CATH domains: 3.90.340.10 3.90.440.10
3b3m
Structure of neuronal nos heme domain in complex with a inhibitor (+-)-3-{cis-4'-[(6"-aminopyridin-2"-yl) methyl]pyrrolidin-3'-ylamino}propan-1-ol
Source: Rattus norvegicus. Rat. Expressed in: escherichia coli.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
Bound ligand:   Het Group JI1 is 42.00% similar to enzyme reactant L-arginine
3b3n
Structure of neuronal nos heme domain in complex with a inhibitor (+-)-n1-{cis-4'-[(6"-aminopyridin-2"-yl) methyl]pyrrolidin-3'-yl}ethane-1,2-diamine
Source: Rattus norvegicus. Rat. Expressed in: escherichia coli.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
Bound ligand:   Het Group JI2 is 45.00% similar to enzyme reactant L-arginine
3b3o
Structure of neuronal nos heme domain in complex with a inhibitor (+-)-n1-{cis-4'-[(6"-amino-4"-methylpyridin-2"- yl)methyl]pyrrolidin-3'-yl}-n2-(4'-chlorobenzyl)ethane-1,2- diamine
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (409 residues) CATH domains: 3.90.340.10 3.90.440.10
3b3p
Structure of neuronal nos heme domain in complex with a inhibitor (+-)-n1-{cis-4'-[(6"-amino-4"-methylpyridin-2"- yl)methyl]pyrrolidin-3'-yl}-n2-(4'-chlorobenzyl)ethane-1,2- diamine
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (409 residues) CATH domains: 3.90.340.10 3.90.440.10
3dqr
Structure of neuronal nos d597n/m336v mutant heme domain in complex with a inhibitor (+-)-n1-{cis-4'-[(6"-aminopyridin- 2"-yl)methyl]pyrrolidin-3'-yl}ethane-1,2-diamine
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
Bound ligand:   Het Group JI2 is 45.00% similar to enzyme reactant L-arginine
3dqs
Structure of endothelial nos heme domain in complex with a i (+-)-n1-{cis-4'-[(6"-amino-4"-methylpyridin-2"-yl)methyl]py 3'-yl}-n2-(4'-chlorobenzyl)ethane-1,2-diamine
Source: Bos taurus. Bovine. Organism_taxid: 9913. Expressed in: escherichia coli.
Chains: A, B (405 residues) CATH domains: 3.90.340.10 3.90.440.10
3dqt
Structure of endothelial nos heme domain in complex with a i (+-)-n1-{trans-4'-[(6"-amino-4"-methylpyridin-2"-yl) methyl]pyrrolidin-3'-yl}-n2-(3'-chlorobenzyl)ethane-1,2-dia
Source: Bos taurus. Bovine. Organism_taxid: 9913. Gene: nos3. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (405 residues) CATH domains: 3.90.340.10 3.90.440.10
3dwj
Heme-proximal w188h mutant of inducible nitric oxide synthase
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: nos2, inosl. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (408 residues) CATH domains: 3.90.340.10 3.90.440.10
3e65
Murine inos dimer with heme, pterin and inhibitor ar-c120011
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: nos2, inosl. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (417 residues) CATH domains: 3.90.340.10 3.90.440.10
3e67
Murine inos dimer with inhibitor 4-map bound
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: nos2, inosl. Expressed in: escherichia coli
Chains: A, B (413 residues) CATH domains: 3.90.340.10 3.90.440.10
Bound ligand:   Het Group BVF is 53.85% similar to enzyme reactant L-arginine
3e68
Structure of murine inos oxygenase domain with inhibitor ar- c130232
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: nos2, inosl. Expressed in: escherichia coli
Chains: A, B (415 residues) CATH domains: 3.90.340.10 3.90.440.10
3e6l
Structure of murine inos oxygenase domain with inhibitor ar- c132283
Source: Mus musculus. Organism_taxid: 10090. Expressed in: escherichia coli
Chains: A, B (413 residues) CATH domains: 3.90.340.10 3.90.440.10
3e6n
Structure of murine inos oxygenase domain with inhibitor ar- c125813
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: nos2, inosl. Expressed in: escherichia coli
Chains: A, B (413 residues) CATH domains: 3.90.340.10 3.90.440.10
Bound ligand:   Het Group AS3 is 43.00% similar to enzyme reactant L-arginine
3e6o
Structure of murine inos oxygenase domain with inhibitor ar- c124355
Source: Mus musculus. Mouse. Organism_taxid: 10090. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (415 residues) CATH domains: 3.90.340.10 3.90.440.10
3e6t
Structure of murine inos oxygenase domain with inhibitor ar- c118901
Source: Mus musculus. Organism_taxid: 10090. Expressed in: escherichia coli
Chains: A, B (415 residues) CATH domains: 3.90.340.10 3.90.440.10
3e7g
Structure of human inosox with inhibitor ar-c95791
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli
Chains: A, B, C, D (421 residues) CATH domains: 3.90.340.10 3.90.440.10
3e7i
Structure of murine inos oxygenase domain with inhibitor ar- c94864
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: nos2, inosl. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (420 residues) CATH domains: 3.90.340.10 3.90.440.10
3e7m
Structure of murine inos oxygenase domain with inhibitor ar-
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: nos2, inosl. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (416 residues) CATH domains: 3.90.340.10 3.90.440.10
3e7s
Structure of bovine enos oxygenase domain with inhibitor ar- c95791
Source: Bos taurus. Bovine. Organism_taxid: 9913. Gene: nos3. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (403 residues) CATH domains: 3.90.340.10 3.90.440.10
3e7t
Structure of murine inos oxygenase domain with inhibitor ar- c102222
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: nos2, inosl. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (413 residues) CATH domains: 3.90.340.10 3.90.440.10
3eah
Structure of inhibited human enos oxygenase domain
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: nos3. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (399 residues) CATH domains: 3.90.340.10 3.90.440.10
3eai
Structure of inhibited murine inos oxygenase domain
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: nos2, inosl. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (421 residues) CATH domains: 3.90.340.10 3.90.440.10
3ebd
Structure of inhibited murine inos oxygenase domain
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: nos2, inosl. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (421 residues) CATH domains: 3.90.340.10 3.90.440.10
Bound ligand:   Het Group 329 is 41.00% similar to enzyme reactant L-arginine
3ebf
Structure of inhibited murine inos oxygenase domain
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: nos2, inosl. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (421 residues) CATH domains: 3.90.340.10 3.90.440.10
3ej8
Structure of double mutant of human inos oxygenase domain with bound immidazole
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: nos2a, nos2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (421 residues) CATH domains: 3.90.340.10 3.90.440.10
Bound ligand:   Het Group IMD is 41.00% similar to enzyme reactant L-arginine
3fc5
G586s mutant nnosoxy
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: nos1 or bnos. Expressed in: escherichia coli. Expression_system_taxid: 511693.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
Bound ligand:   Het Group ARG corresponds to enzyme reactant L-arginine
3gof
Calmodulin bound to peptide from macrophage nitric oxide synthase
Source: Gallus gallus. Chicken. Organism_taxid: 9031. Gene: calm, cam, rcjmb04_24e7. Expressed in: escherichia coli. Expression_system_taxid: 562. Synthetic: yes. Other_details: the peptide is naturally found in mus musculus (mouse).
Chains: C, D (16 residues)
3hr4
Human inos reductase and calmodulin complex
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: calmodulin, inducible nitric oxide synthase, nos2, no expressed in: escherichia coli. Expression_system_taxid: 562. Gene: calm1, calm, cam, cam1, calm2, cam2, camb, calm3, cal cam3, camc, camiii.
Chains: A, C, E, G (189 residues) CATH domains: Unassigned 3.40.50.360
3hsn
Ternary structure of neuronal nitric oxide synthase with nha bound
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (411 residues) CATH domains: 3.90.340.10 3.90.440.10
Bound ligand:   Het Group HAR is 92.31% similar to enzyme reactant L-arginine
3hso
Ternary structure of neuronal nitric oxide synthase with nha and no bound(1)
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (411 residues) CATH domains: 3.90.340.10 3.90.440.10
Bound ligands:   Het Group HAR is 92.00% similar to enzyme reactant L-arginine
  Het Group NO corresponds to enzyme product Nitric oxide
3hsp
Ternary structure of neuronal nitric oxide synthase with nha bound(2)
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (412 residues) CATH domains: 3.90.340.10 3.90.440.10
Bound ligands:   Het Group HAR is 92.31% similar to enzyme reactant L-arginine
  Het Group NO corresponds to enzyme product Nitric
3jt3
Structure of neuronal nitric oxide synthase heme domain complexed with n~5~-[2-(methylsulfanyl)ethanimidoyl]-l- ornithine
Source: Rattus norvegicus. Brown rat,rat,rats. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
Bound ligand:   Het Group JM2 is 73.00% similar to enzyme reactant L-arginine
3jt4
Structure of neuronal nitric oxide synthase heme domain complexed with n~5~-[(3-(ethylsulfanyl)propanimidoyl]-l- ornithine
Source: Rattus norvegicus. Brown rat,rat,rats. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (409 residues) CATH domains: 3.90.340.10 3.90.440.10
Bound ligand:   Het Group JM8 is 64.00% similar to enzyme reactant L-arginine
3jt5
Structure of neuronal nitric oxide synthase heme domain complexed with n~5~-[2-(ethylsulfanyl)ethanimidoyl]-l- ornithine
Source: Rattus norvegicus. Brown rat,rat,rats. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
Bound ligand:   Het Group JM7 is 68.00% similar to enzyme reactant L-arginine
3jt6
Structure of neuronal nitric oxide synthase heme domain complexed with n~5~-[4-(methylsulfanyl)butanimidoyl]-l- ornithine
Source: Rattus norvegicus. Brown rat,rat,rats. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
Bound ligand:   Het Group JM6 is 64.00% similar to enzyme reactant L-arginine
3jt7
Structure of neuronal nitric oxide synthase heme domain complexed with n~5~-[2-(propylsulfanyl)ethanimidoyl]-l- ornithine
Source: Rattus norvegicus. Organism_taxid: 10116. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
Bound ligand:   Het Group JM5 is 64.00% similar to enzyme reactant L-arginine
3jt8
Structure of neuronal nitric oxide synthase heme domain complexed with n~5~-{3-[(1-methylethyl) sulfanyl]propanimidoyl}-l-ornithine
Source: Rattus norvegicus. Brown rat,rat,rats. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
Bound ligand:   Het Group JM4 is 61.00% similar to enzyme reactant L-arginine
3jt9
Structure of neuronal nitric oxide synthase heme domain in the ferrous state complexed with n~5~-[2-(ethylsulfanyl) ethanimidoyl]-l-ornithine
Source: Rattus norvegicus. Organism_taxid: 10116. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
Bound ligand:   Het Group JM7 is 68.00% similar to enzyme reactant L-arginine
3jta
Structure of neuronal nitric oxide synthase heme domain in the ferrous state complexed with n~5~-[4-(methylsulfanyl) butanimidoyl]-l-ornithine
Source: Rattus norvegicus. Organism_taxid: 10116. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
Bound ligand:   Het Group JM6 is 64.00% similar to enzyme reactant L-arginine
3jws
Structure of neuronal nitric oxide synthase r349a mutant hem complexed with n1-[(3' s,4's)-4'-((6"-amino-4"-methylpyridi methyl)pyrrolidin-3'-yl]-n2-(3'-fluorophenethyl)ethane-1,2- tetrahydrochloride
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
3jwt
Structure of rat neuronal nitric oxide synthase r349a mutant domain in complex with n1-{(3'r,4'r)-4'-[(6"-amino-4"-methy 2"-yl)methyl]pyrrolidin-3'-yl}-n2-(3'-fluorophenethyl)ethan diamine
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
3jwu
Structure of rat neuronal nitric oxide synthase r349a mutant domain in complex with n1-{(3'r,4's)-4'-[(6"-amino-4"-methy 2"-yl)methyl]pyrrolidin-3'-yl}-n2-(3'-fluorophenethyl)ethan diamine tetrahydrochloride
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
3jwv
Structure of rat neuronal nitric oxide synthase r349a mutant domain in complex with n1-{(3's,4'r)-4'-[(6"-amino-4"-methy 2"-yl)methyl]pyrrolidin-3'-yl}-n2-(3'-fluorophenethyl)ethan diamine
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
3jww
Structure of endothelial nitric oxide synthase heme domain c with n1-[(3's,4's)-4'-((6"-amino-4"-methylpyridin-2"-yl)met pyrrolidin-3'-yl]-n2- (3'-fluorophenethyl)ethane-1,2-diamin tetrahydrochloride
Source: Bos taurus. Bovine. Organism_taxid: 9913. Gene: nos3. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (404 residues) CATH domains: 3.90.340.10 3.90.440.10
3jwx
Structure of endothelial nitric oxide synthase heme domain c with n1-[(3'r,4'r)-4'-((6"-amino-4"-methylpyridin-2"-yl)met pyrrolidin-3'-yl]-n2-(3'-fluorophenethyl)ethane-1,2-diamine tetrahydrochloride
Source: Bos taurus. Bovine. Organism_taxid: 9913. Gene: nos3. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (403 residues) CATH domains: 3.90.340.10 3.90.440.10
3jwy
Structure of endothelial nitric oxide synthase heme domain c with n1-{(3'r,4's)-4'-[(6"-amino-4"-methylpyridin-2"-yl) methyl]pyrrolidin-3'-yl}-n2-(3'-fluorophenethyl)ethane-1,2- tetrahydrochloride
Source: Bos taurus. Bovine. Organism_taxid: 9913. Gene: nos3. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (403 residues) CATH domains: 3.90.340.10 3.90.440.10
3jwz
Structure of endothelial nitric oxide synthase heme domain c with n1-[(3' s,4' r)-4'-((6"-amino-4"-methylpyridin-2"-yl)m pyrrolidin-3'-yl]-n2-(3'-fluorophenethyl)ethane-1,2-diamine tetrahydrochloride
Source: Bos taurus. Bovine. Organism_taxid: 9913. Gene: nos3. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (405 residues) CATH domains: 3.90.340.10 3.90.440.10
3jx0
Structure of rat neuronal nitric oxide synthase d597n mutant domain in complex with n1-{(3's,4's)-4'-[(6"-amino-4"-methy 2"-yl)methyl]pyrrolidin-3'-yl}-n2-(3'-fluorophenethyl)ethan diamine
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
3jx1
Structure of rat neuronal nitric oxide synthase d597n mutant domain in complex with n1-{(3'r,4'r)-4'-[(6"-amino-4"-methy 2"-yl)methyl]pyrrolidin-3'-yl}-n2-(3'-fluorophenethyl)ethan diamine
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
3jx2
Structure of rat neuronal nitric oxide synthase d597n/m336v heme domain in complex with n1-{(3's,4's)-4'-[(6"-amino-4"- methylpyridin-2"-yl)methyl]pyrrolidin-3'-yl}-n2-(3'-fluorop ethane-1,2-diamine
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (409 residues) CATH domains: 3.90.340.10 3.90.440.10
3jx3
Structure of rat neuronal nitric oxide synthase d597n/m336v heme domain in complex with n1-{(3'r,4'r)-4'-[(6"-amino-4"- methylpyridin-2"-yl)methyl]pyrrolidin-3'-yl}-n2-(3'-fluorop ethane-1,2-diamine
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
3jx4
Structure of rat neuronal nitric oxide synthase d597n/m336v heme domain in complex with n1-{(3'r,4's)-4'-[(6"-amino-4"- methylpyridin-2"-yl)methyl]pyrrolidin-3'-yl}-n2-(3'-fluorop ethane-1,2-diamine
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
3jx5
Structure of rat neuronal nitric oxide synthase d597n/m336v heme domain in complex with n1-{(3's,4'r)-4'-[(6"-amino-4"- methylpyridin-2"-yl)methyl]pyrrolidin-3'-yl}-n2-(3'-fluorop ethane-1,2-diamine
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
3jx6
Structure of neuronal nitric oxide synthase d597n/m336v/y706 heme domain complexed with n1-[(3' r,4' r)-4'-((6"-amino-4" methylpyridin-2"-yl)methyl)pyrrolidin-3'-yl]-n2-(3'-fluorop ethane-1,2-diamine tetrahydrochloride
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
3n2r
Structure of neuronal nitric oxide synthase heme domain in c with 6-(((3r,4r/3s,4s)-4-(3-phenoxyphenoxy)pyrrolidin-3-yl) pyridin-2-amine
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
3n5p
Structure of endothelial nitric oxide synthase heme domain c with 4-(2-(6-(2-(6-amino-4-methylpyridin-2-yl)ethyl)pyridin ethyl)-6-methylpyridin-2-amine
Source: Bos taurus. Cow. Organism_taxid: 9913. Gene: nos3. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (405 residues) CATH domains: 3.90.340.10 3.90.440.10
3n5q
Structure of endothelial nitric oxide synthase heme domain c with 6,6'-(2,2'-(5-amino-1,3-phenylene)bis(ethane-2,1-diyl) methylpyridin-2-amine)
Source: Bos taurus. Cow. Organism_taxid: 9913. Gene: nos3. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (403 residues) CATH domains: 3.90.340.10 3.90.440.10
3n5r
Structure of endothelial nitric oxide synthase heme domain c with 4-(3-(2-(6-amino-4-methylpyridin-2-yl)ethyl)phenethyl) methylpyridin-2-amine
Source: Bos taurus. Cow. Organism_taxid: 9913. Gene: nos3. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (406 residues) CATH domains: 3.90.340.10 3.90.440.10
3n5s
Structure of endothelial nitric oxide synthase heme domain c with 4-(2-(5-(2-(6-amino-4-methylpyridin-2-yl)ethyl)pyridin ethyl)-6-methylpyridin-2-amine
Source: Bos taurus. Cow. Organism_taxid: 9913. Gene: nos3. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (404 residues) CATH domains: 3.90.340.10 3.90.440.10
3n5t
Structure of endothelial nitric oxide synthase heme domain c with 6,6'-(2,2'-(pyridine-3,5-diyl)bis(ethane-2,1-diyl))bis methylpyridin-2-amine)
Source: Bos taurus. Cow. Organism_taxid: 9913. Gene: nos3. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (405 residues) CATH domains: 3.90.340.10 3.90.440.10
3n5v
Structure of neuronal nitric oxide synthase heme domain in c with 4-(3-(2-(6-amino-4-methylpyridin-2-yl)ethyl)phenethyl) methylpyridin-2-amine
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: nos3. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
3n5w
Structure of neuronal nitric oxide synthase heme domain in c with 6,6'-(2,2'-(pyridine-3,5-diyl)bis(ethane-2,1-diyl))bis methylpyridin-2-amine)
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: nos3. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
3n5x
Structure of neuronal nitric oxide synthase heme domain in c with 4-(2-(5-(2-(6-amino-4-methylpyridin-2-yl)ethyl)pyridin ethyl)-6-methylpyridin-2-amine
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: nos3. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
3n5y
Structure of neuronal nitric oxide synthase heme domain in c with 6,6'-(2,2'-(pyridine-2,6-diyl)bis(ethane-2,1-diyl))bis methylpyridin-2-amine)
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: nos3. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
3n5z
Structure of neuronal nitric oxide synthase heme domain in c with 4-(2-(6-(2-(6-amino-4-methylpyridin-2-yl)ethyl)pyridin ethyl)-6-methylpyridin-2-amine
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: nos3. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
3n60
Structure of neuronal nitric oxide synthase heme domain in c with 6,6'-(2,2'-(5-amino-1,3-phenylene)bis(ethane-2,1-diyl) methylpyridin-2-amine)
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: nos3. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
3n61
Structure of neuronal nitric oxide synthase d597n/m336v muta domain in complex with 6,6'-(2,2'-(pyridine-3,5-diyl)bis(et diyl))bis(4-methylpyridin-2-amine)
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: nos3. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
3n62
Structure of neuronal nitric oxide synthase d597n mutant hem in complex with 6,6'-(2,2'-(pyridine-3,5-diyl)bis(ethane-2, bis(4-methylpyridin-2-amine)
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: nos3. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
3n63
Structure of neuronal nitric oxide synthase d597n/m336v muta domain in complex with 6,6'-(2,2'-(5-amino-1,3-phenylene)bi 2,1-diyl))bis(4-methylpyridin-2-amine)
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: nos3. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
3n64
Structure of neuronal nitric oxide synthase d597n mutant hem in complex with 6,6'-(2,2'-(5-amino-1,3-phenylene)bis(ethan diyl))bis(4-methylpyridin-2-amine)
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: nos3. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
3n65
Structure of neuronal nitric oxide synthase s602h mutant hem in complex with 6,6'-(2,2'-(pyridine-3,5-diyl)bis(ethane-2, bis(4-methylpyridin-2-amine)
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: nos3. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
3n66
Structure of neuronal nitric oxide synthase s602h mutant hem in complex with 6,6'-(2,2'-(5-amino-1,3-phenylene)bis(ethan diyl))bis(4-methylpyridin-2-amine)
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: nos3. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
3n67
Structure of endothelial nitric oxide synthase n368d/v106m d mutant heme domain complexed with 6,6'-(2,2'-(5-amino-1,3-p bis(ethane-2,1-diyl))bis(4-methylpyridin-2-amine)
Source: Bos taurus. Cow. Organism_taxid: 9913. Gene: nos3. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (404 residues) CATH domains: 3.90.340.10 3.90.440.10
3n68
Structure of endothelial nitric oxide synthase heme domain n double mutant complexed with 4-(3-(2-(6-amino-4-methylpyrid ethyl)phenethyl)-6-methylpyridin-2-amine
Source: Bos taurus. Cow. Organism_taxid: 9913. Gene: nos3. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (404 residues) CATH domains: 3.90.340.10 3.90.440.10
3n69
Structure of endothelial nitric oxide synthase n368d/v106m d mutant heme domain complexed with 6,6'-(2,2'-(pyridine-3,5- bis(ethane-2,1-diyl))bis(4-methylpyridin-2-amine)
Source: Bos taurus. Cow. Organism_taxid: 9913. Gene: nos3. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (404 residues) CATH domains: 3.90.340.10 3.90.440.10
3n6a
Structure of endothelial nitric oxide synthase n368d/v106m d mutant heme domain complexed with 4-(2-(5-(2-(6-amino-4- methylpyridin-2-yl)ethyl)pyridin-3-yl)ethyl)-6-methylpyridi
Source: Bos taurus. Cow. Organism_taxid: 9913. Gene: nos3. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (406 residues) CATH domains: 3.90.340.10 3.90.440.10
3n6b
Structure of endothelial nitric oxide synthase h373s single heme domain complexed with 6,6'-(2,2'-(pyridine-3,5-diyl)bi 2,1-diyl))bis(4-methylpyridin-2-amine)
Source: Bos taurus. Cow. Organism_taxid: 9913. Gene: nos3. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (404 residues) CATH domains: 3.90.340.10 3.90.440.10
3n6c
Structure of endothelial nitric oxide synthase h373s single heme domain complexed with 4-(2-(6-(2-(6-amino-4-methylpyri ethyl)pyridin-2-yl)ethyl)-6-methylpyridin-2-amine
Source: Bos taurus. Cow. Organism_taxid: 9913. Gene: nos3. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (404 residues) CATH domains: 3.90.340.10 3.90.440.10
3n6d
Structure of endothelial nitric oxide synthase h373s single heme domain complexed with 6,6'-(2,2'-(5-amino-1,3-phenylen bis(ethane-2,1-diyl))bis(4-methylpyridin-2-amine)
Source: Bos taurus. Cow. Organism_taxid: 9913. Gene: nos3. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (404 residues) CATH domains: 3.90.340.10 3.90.440.10
3n6e
Structure of endothelial nitric oxide synthase n368d mutant domain complexed with 6,6'-(2,2'-(5-amino-1,3-phenylene)bis 1-diyl))bis(4-methylpyridin-2-amine)
Source: Bos taurus. Cow. Organism_taxid: 9913. Gene: nos3. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (405 residues) CATH domains: 3.90.340.10 3.90.440.10
3n6f
Structure of endothelial nitric oxide synthase n368d single heme domain complexed with 6,6'-(2,2'-(pyridine-3,5-diyl)bi 2,1-diyl))bis(4-methylpyridin-2-amine)
Source: Bos taurus. Cow. Organism_taxid: 9913. Gene: nos3. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (404 residues) CATH domains: 3.90.340.10 3.90.440.10
3n6g
Structure of endothelial nitric oxide synthase n368d single heme domain complexed with 4-(2-(5-(2-(6-amino-4-methylpyri ethyl)pyridin-3-yl)ethyl)-6-methylpyridin-2-amine
Source: Bos taurus. Cow. Organism_taxid: 9913. Gene: nos3. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (405 residues) CATH domains: 3.90.340.10 3.90.440.10
3nld
Structure of endothelial nitric oxide synthase heme domain c with 6-{{(3's,4's)-3'-[2"-(3'''-fluorophenethylamino) ethoxy]pyrrolidin-4'-yl}methyl}-4-methylpyridin-2-amine
Source: Bos taurus. Bovine,cow,domestic cattle,domestic cow. Organism_taxid: 9913. Gene: nos3. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (403 residues) CATH domains: 3.90.340.10 3.90.440.10
3nle
Structure of endothelial nitric oxide synthase heme domain c with 6-{{(3'r,4'r)-3'-[2"-(3'''-fluorophenethylamino) ethoxy]pyrrolidin-4'-yl}methyl}-4-methylpyridin-2-amine
Source: Bos taurus. Bovine,cow,domestic cattle,domestic cow. Organism_taxid: 9913. Gene: nos3. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (404 residues) CATH domains: 3.90.340.10 3.90.440.10
3nlf
Structure of endothelial nitric oxide synthase heme domain c with 6-{{(3'r,4's)-3'-[2"-(3'''-fluorophenethylamino) ethoxy]pyrrolidin-4'-yl}methyl}-4-methylpyridin-2-amine
Source: Bos taurus. Bovine,cow,domestic cattle,domestic cow. Organism_taxid: 9913. Gene: nos3. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (404 residues) CATH domains: 3.90.340.10 3.90.440.10
3nlg
Structure of endothelial nitric oxide synthase heme domain c with 6-{{(3's,4'r)-3'-[2"-(3'''-fluorophenethylamino) ethoxy]pyrrolidin-4'-yl}methyl}-4-methylpyridin-2-amine
Source: Bos taurus. Bovine,cow,domestic cattle,domestic cow. Organism_taxid: 9913. Gene: nos3. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (404 residues) CATH domains: 3.90.340.10 3.90.440.10
3nlh
Structure of endothelial nitric oxide synthase heme domain n mutant complexed with 6-{{(3's,4's)-3'-[2"-(3'''- fluorophenethylamino)ethoxy]pyrrolidin-4'-yl}methyl}-4-meth 2-amine
Source: Bos taurus. Bovine,cow,domestic cattle,domestic cow. Organism_taxid: 9913. Gene: nos3. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (402 residues) CATH domains: 3.90.340.10 3.90.440.10
3nli
Structure of endothelial nitric oxide synthase n368d mutant domain complexed with 6-{{(3'r,4'r)-3'-[2"-(3'''- fluorophenethylamino)ethoxy]pyrrolidin-4'-yl}methyl}-4-meth 2-amine
Source: Bos taurus. Bovine,cow,domestic cattle,domestic cow. Organism_taxid: 9913. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (404 residues) CATH domains: 3.90.340.10 3.90.440.10
3nlj
Structure of neuronal nitric oxide synthase d597n/m336v/y706 mutant heme domain complexed with 6-{{(3'r,4'r)-3'-[2"-(3'' fluorophenethylamino)ethoxy] pyrrolidin-4'-yl}methyl}-4- methylpyridin-2-amine
Source: Rattus norvegicus. Brown rat,rat,rats. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
3nlk
Structure of neuronal nitric oxide synthase r349a mutant hem in complex with 6-{{(3's,4's)-3'-[2"-(3'''-fluorophenethyla ethoxy]pyrrolidin-4'-yl}methyl}-4-methylpyridin-2-amine
Source: Rattus norvegicus. Brown rat,rat,rats. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
3nlm
Structure of neuronal nitric oxide synthase heme domain in c with 6-{{(3'r,4'r)-3'-[2"-(3'''-fluorophenethylamino) ethoxy]pyrrolidin-4'-yl}methyl}-4-methylpyridin-2-amine
Source: Rattus norvegicus. Brown rat,rat,rats. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (409 residues) CATH domains: 3.90.340.10 3.90.440.10
3nln
Structure of neuronal nitric oxide synthase r349a mutant hem in complex with 6-{{(3'r,4's)-3'-[2"-(3'''-fluorophenethyla ethoxy]pyrrolidin-4'-yl}methyl}-4-methylpyridin-2-amine
Source: Rattus norvegicus. Brown rat,rat,rats. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
3nlo
Structure of neuronal nitric oxide synthase r349a mutant hem in complex with 6-{{(3's,4'r)-3'-[2"-(3'''-fluorophenethyla ethoxy]pyrrolidin-4'-yl}methyl}-4-methylpyridin-2-amine
Source: Rattus norvegicus. Brown rat,rat,rats. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
3nlp
Structure of neuronal nitric oxide synthase d597n/m336v muta domain in complex with 6-{{(3's,4's)-3'-[2"-(3'''- fluorophenethylamino)ethoxy]pyrrolidin-4'-yl}methyl}-4-meth 2-amine
Source: Rattus norvegicus. Brown rat,rat,rats. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
3nlq
Structure of neuronal nitric oxide synthase d597n/m336v muta domain in complex with 6-{{(3'r,4'r)-3'-[2"-(3'''- fluorophenethylamino)ethoxy]pyrrolidin-4'-yl}methyl}-4-meth 2-amine
Source: Rattus norvegicus. Brown rat,rat,rats. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
3nlr
Structure of neuronal nitric oxide synthase d597n/m336v muta domain in complex with 6-{{(3'r,4's)-3'-[2"-(3'''- fluorophenethylamino)ethoxy]pyrrolidin-4'-yl}methyl}-4-meth 2-amine
Source: Rattus norvegicus. Brown rat,rat,rats. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
3nlt
Structure of endothelial nitric oxide synthase heme domain c with n1-{(3's,4's)-4'-[(6"-amino-4"-methylpyridin-2"-yl) methyl]pyrrolidin-3'-yl}- n2-(3'-fluorophenethyl)ethane-1,2 tetrahydrochloride
Source: Bos taurus. Bovine,cow,domestic cattle,domestic cow. Organism_taxid: 9913. Gene: nos3. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (403 residues) CATH domains: 3.90.340.10 3.90.440.10
3nlu
Structure of endothelial nitric oxide synthase heme domain c with n1-{(3'r,4'r)-4'-[(6"-amino-4"-methylpyridin-2"-yl) methyl]pyrrolidin-3'-yl}-n2-(3'-fluorophenethyl)ethane-1,2- tetrahydrochloride
Source: Bos taurus. Bovine,cow,domestic cattle,domestic cow. Organism_taxid: 9913. Gene: nos3. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (405 residues) CATH domains: 3.90.340.10 3.90.440.10
3nlv
Structure of rat neuronal nitric oxide synthase heme domain with 6-(((3s,4s)-4-(2-(2,2-difluoro-2-(3-fluorophenyl)ethyl ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine
Source: Rattus norvegicus. Brown rat,rat,rats. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
3nlw
Structure of rat neuronal nitric oxide synthase heme domain with 6-(((3s,4s)-4-(2-(2,2-difluoro-2-(piperidin-2-yl)ethyl ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine
Source: Rattus norvegicus. Brown rat,rat,rats. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
3nlx
Structure of rat neuronal nitric oxide synthase heme domain with 6-(((3r,4r)-4-(2- (2,2-difluoro-2-(3-fluorophenyl)ethy ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine
Source: Rattus norvegicus. Brown rat,rat,rats. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
3nly
Structure of rat neuronal nitric oxide synthase heme domain with 6-(((3r,4r)-4-(2- (2,2-difluoro-2-(4-fluorophenyl)ethy ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine
Source: Rattus norvegicus. Brown rat,rat,rats. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
3nlz
Structure of rat neuronal nitric oxide synthase heme domain with 6-(((3r,4r)-4-(2-(2,2-difluoro-2-phenylethylamino)etho pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine
Source: Rattus norvegicus. Brown rat,rat,rats. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (409 residues) CATH domains: 3.90.340.10 3.90.440.10
3nm0
Structure of rat neuronal nitric oxide synthase heme domain with 6-(((3r,4r)-4-(2-(2,2-difluoro-2-phenylethylamino)etho pyrrolidin-3-yl)methyl)-4-methyl-3,4,5,6-tetrahydropyridin-
Source: Rattus norvegicus. Brown rat,rat,rats. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (409 residues) CATH domains: 3.90.340.10 3.90.440.10
3nny
Structure of rat neuronal nitric oxide synthase heme domain with 6-(((3r,4r)-4-(2-(3-fluorophenethylamino)ethoxy)pyrrol yl)methyl)pyridin-2-amine
Source: Rattus norvegicus. Brown rat,rat,rats. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
3nnz
Structure of rat neuronal nitric oxide synthase heme domain with 6-(((3s,4s)-4-(2-(3-fluorophenethylamino)ethoxy)pyrrol yl)methyl)pyridin-2-amine
Source: Rattus norvegicus. Brown rat,rat,rats. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
3nod
Murine inducible nitric oxide synthase oxygenase dimer (delt tetrahydrobiopterin and product analogue l-thiocitrulline
Source: Mus musculus. House mouse. Organism_taxid: 10090. Cell: macrophage. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (414 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group SCI is 84.62% similar to enzyme reactant L-arginine
3nos
Human endothelial nitric oxide synthase with arginine substr
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (400 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group HAR is 92.31% similar to enzyme reactant L-arginine
3nqs
Crystal structure of inducible nitric oxide synthase with n- nitrosated-pterin
Source: Mus musculus. Mouse. Organism_taxid: 10090. Strain: macrophage. Gene: inosl, nos2. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (412 residues) CATH domains: 3.90.340.10 3.90.440.10
Bound ligand:   Het Group NO corresponds to enzyme product Nitric oxide
3nse
Bovine enos, h4b-free, seitu complex
Source: Bos taurus. Cattle. Organism_taxid: 9913. Cell: endothelial. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chains: A, B (416 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group ARG corresponds to enzyme reactant L-arginine
3nw2
Novel nanomolar imidazopyridines as selective nitric oxide s (inos) inhibitors: sar and structural insights
Source: Mus musculus. Mouse. Organism_taxid: 10090. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (414 residues) CATH domains: 3.90.340.10 3.90.440.10
Bound ligand:   Het Group MPW is 40.91% similar to enzyme reactant L-arginine
3pne
Structure of rat neuronal nitric oxide synthase heme domain with 6-(((3r,4r)-4-(2-((2,2-difluoro-2-(3-chlorophenyl)ethy ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine
Source: Rattus norvegicus. Brown rat,rat,rats. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (410 residues) CATH domains: 3.90.340.10 3.90.440.10
3pnf
Structure of rat neuronal nitric oxide synthase heme domain with 6-(((3r,4r)-4-(2-((2,2-difluoro-2-(2-chlorophenyl)ethy ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine
Source: Rattus norvegicus. Brown rat,rat,rats. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (409 residues) CATH domains: 3.90.340.10 3.90.440.10
3png
Structure of rat neuronal nitric oxide synthase heme domain with 6-(((3r,4r)-4-(2-((2-fluoro-2-(3-fluorophenyl)ethyl)am ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine
Source: Rattus norvegicus. Brown rat,rat,rats. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (409 residues) CATH domains: 3.90.340.10 3.90.440.10
3pnh
Structure of bovine endothelial nitric oxide synthase heme d complex with 6-(((3r,4r)-4-(2-((2-fluoro-2-(3-fluorophenyl) amino)ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amin
Source: Bos taurus. Bovine,cow,domestic cattle,domestic cow. Organism_taxid: 9913. Gene: nos3. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (404 residues) CATH domains: 3.90.340.10 3.90.440.10
3q99
Structure of neuronal nitric oxide synthase in the ferric st complex with n~5~-[(3-(ethylsulfanyl)propanimidoyl]-l-ornit
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
Bound ligand:   Het Group JM8 is 64.71% similar to enzyme reactant L-arginine
3q9a
Structure of neuronal nitric oxide synthase in the ferric st complex with n-5-[2-(ethylsulfanyl)ethanimidoyl]-l-ornithin
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
Bound ligand:   Het Group JM7 is 68.75% similar to enzyme reactant L-arginine
3rqj
Structure of the neuronal nitric oxide synthase heme domain with 6-(((3r,4r)-4-(2-((1s,2r)-2-(3-fluorophenyl)cyclopropy ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amine
Source: Rattus norvegicus. Brown rat,rat,rats. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
3rqk
Structure of the neuronal nitric oxide synthase heme domain with 4-methyl-6-{[(3r,4r)-4-(2-{[(1r,2s)-2-(3-methylphenyl) cyclopropyl]amino}ethoxy)pyrrolidin-3-yl]methyl}pyridin-2-a its isomer
Source: Rattus norvegicus. Brown rat,rat,rats. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
3rql
Structure of the neuronal nitric oxide synthase heme domain with 6-(((3r,4r)-4-(2-((1s,2r/1r,2s)-2-(3-clorophenyl) cyclopropylamino)ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyr amine
Source: Rattus norvegicus. Brown rat,rat,rats. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (409 residues) CATH domains: 3.90.340.10 3.90.440.10
3rqm
Structure of the neuronal nitric oxide synthase heme domain with 6-{[(3r,4r)-4-(2-{[(2r/2s)-1-(3-fluorophenyl)propan-2- yl]amino}ethoxy)pyrrolidin-3-yl]methyl}-4-methylpyridin-2-a
Source: Rattus norvegicus. Brown rat,rat,rats. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
3rqn
Structure of the neuronal nitric oxide synthase heme domain with 6-(((3 R ,4 R )-4-(2-((( S )-1-(3-Fluorophenyl)propan amino)ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amin
Source: Rattus norvegicus. Brown rat,rat,rats. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (409 residues) CATH domains: 3.90.340.10 3.90.440.10
3rqo
Structure of the endothelial nitric oxide synthase heme doma complex with 6-(((3r,4r)-4-(2-((1s,2r/1r,2s)-2-(3-clorophen cyclopropylamino)ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyr amine
Source: Bos taurus. Bovine,cow,domestic cattle,domestic cow. Organism_taxid: 9913. Gene: nos3. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (404 residues) CATH domains: 3.90.340.10 3.90.440.10
3rqp
Structure of the endothelial nitric oxide synthase heme doma complex with 6-{[(3r,4r)-4-(2-{[(2r/2s)-1-(3-fluorophenyl)p yl]amino}ethoxy)pyrrolidin-3-yl]methyl}-4-methylpyridin-2-a
Source: Bos taurus. Bovine,cow,domestic cattle,domestic cow. Organism_taxid: 9913. Gene: nos3. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (405 residues) CATH domains: 3.90.340.10 3.90.440.10
3svp
Structure of rat neuronal nitric oxide synthase heme domain with 6-(((3r,4r)-4-(2-((2,2-difluoro-2-(3-chloro-5-fluoroph ethyl)amino)ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-
Source: Rattus norvegicus. Brown rat,rat,rats. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
3svq
Structure of rat neuronal nitric oxide synthase heme domain with 6-(((3r,4r)-4-(2-((2,2-difluoro-2-(2,3-difluorophenyl) amino)ethoxy)pyrrolidin-3-yl)methyl)-4-methylpyridin-2-amin
Source: Rattus norvegicus. Brown rat,rat,rats. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
3tyl
Structure of neuronal nitric oxide synthase heme domain in c with 6-(((3s,4s)-4-(2-((2-fluorobenzyl)amino)ethoxy)pyrroli methyl)-4-methylpyridin-2-amine
Source: Rattus norvegicus. Brown rat,rat,rats. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (409 residues) CATH domains: 3.90.340.10 3.90.440.10
3tym
Structure of neuronal nitric oxide synthase heme domain in c with 6-(((3s,4s)-4-(2-((2-methoxybenzyl)amino)ethoxy)pyrrol yl)methyl)-4-methylpyridin-2-amine
Source: Rattus norvegicus. Brown rat,rat,rats. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
3tyn
Structure of neuronal nitric oxide synthase heme domain in c with 2-(((2-(((3s,4s)-4-((6-amino-4-methylpyridin-2-yl)meth pyrrolidin-3-yl)oxy)ethyl)amino)methyl)phenol
Source: Rattus norvegicus. Brown rat,rat,rats. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
3tyo
Structure of neuronal nitric oxide synthase heme domain in c with 6-(((3s,4s)-4-(2-((furan-2-ylmethyl)amino)ethoxy)pyrro yl)methyl)-4-methylpyridin-2-amine
Source: Rattus norvegicus. Brown rat,rat,rats. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
3ufo
Structure of rat nitric oxide synthase heme domain in comple (((3s,4s)-4-((5-(3-fluorophenyl)pentyl)oxy)pyrrolidin-3-yl) methylpyridin-2-amine
Source: Rattus norvegicus. Brown rat,rat,rats. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
3ufp
Structure of rat nitric oxide synthase heme domain in comple (((3r,4r)-4-((5-(3-fluorophenyl)pentyl)oxy)pyrrolidin-3-yl) methylpyridin-2-amine
Source: Rattus norvegicus. Brown rat,rat,rats. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
3ufq
Structure of rat nitric oxide synthase heme domain in comple (((3s,4s)-4-(((e)-5-(3-fluorophenyl)pent-4-en-1-yl)oxy)pyrr yl)methyl)-4-methylpyridin-2-amine
Source: Rattus norvegicus. Brown rat,rat,rats. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
3ufr
Structure of rat nitric oxide synthase heme domain in comple (((3r,4r)-4-(((e)-5-(3-fluorophenyl)pent-4-en-1-yl)oxy)pyrr yl)methyl)-4-methylpyridin-2-amine
Source: Rattus norvegicus. Brown rat,rat,rats. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
3ufs
Structure of rat nitric oxide synthase heme domain in comple (((3r,4r)-4-((5-(3-chloro-5-fluorophenyl)pentyl)oxy)pyrroli methyl)-4-methylpyridin-2-amine
Source: Rattus norvegicus. Brown rat,rat,rats. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
3uft
Structure of rat nitric oxide synthase heme domain in comple (((3r,4r)-4-(4-(3-chloro-5-fluorophenoxy)butoxy)pyrrolidin- methyl)-4-methylpyridin-2-amine
Source: Rattus norvegicus. Brown rat,rat,rats. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
3ufu
Structure of rat nitric oxide synthase heme domain in comple methyl-6-(((3r,4r)-4-((5-(pyridin-2-yl)pentyl)oxy)pyrrolidi methyl)pyridin-2-amine
Source: Rattus norvegicus. Brown rat,rat,rats. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
3ufv
Structure of rat nitric oxide synthase heme domain in comple methyl-6-(((3r,4r)-4-((5-(4-methylpyridin-2-yl)pentyl)oxy)p 3-yl)methyl)pyridin-2-amine
Source: Rattus norvegicus. Brown rat,rat,rats. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
3ufw
Structure of rat nitric oxide synthase heme domain in comple (((3r,4r)-4-((5-(6-aminopyridin-2-yl)pentyl)oxy)pyrrolidin- methyl)-4-methylpyridin-2-amine
Source: Rattus norvegicus. Brown rat,rat,rats. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
4c39
Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-((((3s, 5r)-5-(((6-amino-4-methylpyridin- 2-yl)methoxy)methyl)pyrrolidin-3-yl)oxy)methyl)-4- methylpyridin-2-amine
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (408 residues) CATH domains: 3.90.340.10 3.90.440.10
4c3a
Structure of bovine endothelial nitric oxide synthase heme domain in complex with 6-((((3s, 5r)-5-(((6-amino-4- methylpyridin-2-yl)methoxy)methyl)pyrrolidin-3-yl)oxy) methyl)-4-methylpyridin-2-amine
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (405 residues) CATH domains: 3.90.340.10 3.90.440.10
4cam
Structure of rat neuronal nitric oxide synthase heme domain complex with 7-((3-fluorophenethylamino)methyl)quinolin-2-a
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
4can
Structure of rat neuronal nitric oxide synthase heme domain complex with 7-(2-(3-fluorobenzylamino)ethyl)quinolin-2-ami
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
4cao
Structure of rat neuronal nitric oxide synthase heme domain in complex with 7-(2-(3-(3-fluorophenyl(propylamino)ethyl)) quinolin-2-amine
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
4cap
Structure of rat neuronal nitric oxide synthase heme domain in complex with 7-(2-(3-(3-fluorophenyl(propylamino)methyl) )quinolin-2-amine
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
4caq
Structure of rat neuronal nitric oxide synthase heme domain complex with 7-((3-chlorophenethylamino)ethyl)quinolin-2-am
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
4car
Structure of bovine endothelial nitric oxide synthase heme domain in complex with 7-((3-fluorophenethylamino)methyl) quinolin-2-amine
Source: Bos taurus. Cattle. Organism_taxid: 9913. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (405 residues) CATH domains: 3.90.340.10 3.90.440.10
4cdt
Structure of rat neuronal nitric oxide synthase heme domain in complex with 7-((3-fluorophenethylamino)ethyl)quinolin- 2-amine
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (408 residues) CATH domains: 3.90.340.10 3.90.440.10
4cft
Structure of bovine endothelial nitric oxide synthase heme domain in complex with 7-((3-fluorophenethylamino)ethyl) quinolin-2-amine
Source: Bos taurus. Cattle. Organism_taxid: 9913. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (405 residues) CATH domains: 3.90.340.10 3.90.440.10
4ctp
Structure of rat neuronal nitric oxide synthase heme domain in complex with (s)-6-(2-amino-2-(3-(2-(6-amino-4- methylpyridin-2-yl)ethyl)phenyl)ethyl)-4-methylpyridin-2- amine
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (408 residues) CATH domains: 3.90.340.10 3.90.440.10
4ctq
Structure of rat neuronal nitric oxide synthase heme domain complex with (r)-6-(2-amino-2-(3-(2-(6-amino-4-methylpyridi ethyl)phenyl)ethyl)-4-methylpyridin-2-amine
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (408 residues) CATH domains: 3.90.340.10 3.90.440.10
4ctr
Structure of rat neuronal nitric oxide synthase heme domain in complex with 2-(6-amino-4-methylpyridin-2-yl)-1-(3-(2-( 6-amino-4-methylpyridin-2-yl)ethyl )phenyl)ethan-1-ol
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (408 residues) CATH domains: 3.90.340.10 3.90.440.10
4ctt
Structure of rat neuronal nitric oxide synthase heme domain in complex with (s)-6-(2-amino-2-(3-(2-(4-methylpyridin-2-y ethyl)phenyl)ethyl)-4-methylpyridin-2-amine
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (408 residues) CATH domains: 3.90.340.10 3.90.440.10
4ctu
Structure of rat neuronal nitric oxide synthase heme domain complex with 6-(3-amino-2-(3-(2-(6-amino-4-methylpyridin-2- ethyl)phenyl)propyl)-4-methylpyridin-2-amine
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (408 residues) CATH domains: 3.90.340.10 3.90.440.10
4ctv
Structure of rat neuronal nitric oxide synthase heme domain in complex with 6-(3-amino-2-(6-(2-(6-amino-4- methylpyridin-2-yl)ethyl)pyridin-2-yl)propyl)-4- methylpyridin-2-amine
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (408 residues) CATH domains: 3.90.340.10 3.90.440.10
4ctw
Structure of rat neuronal nitric oxide synthase heme domain complex with (r)-6-(3-amino-2-(5-(2-(6-amino-4-methylpyridi ethyl)pyridin-3-yl)propyl)-4-methylpyridin-2-amine
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (408 residues) CATH domains: 3.90.340.10 3.90.440.10
4ctx
Structure of rat neuronal nitric oxide synthase heme domain in complex with (s)-6-(3-amino-2-(5-(2-(6-amino-4- methylpyridin-2-yl)ethyl)pyridin-3-yl)propyl)-4- methylpyridin-2-amine
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (408 residues) CATH domains: 3.90.340.10 3.90.440.10
4cty
Structure of bovine endothelial nitric oxide synthase heme d in complex with (r)-6-(2-amino-2-(3-(2-(6-amino-4-methylpyr 2-yl)ethyl)phenyl)ethyl)-4-methylpyridin-2-amine
Source: Bos taurus. Cattle. Organism_taxid: 9913. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (404 residues) CATH domains: 3.90.340.10 3.90.440.10
4ctz
Structure of bovine endothelial nitric oxide synthase heme d complex with (s)-6-(2-amino-2-(3-(2-(4-methylpyridin-2-yl) ethyl)phenyl)ethyl)-4-methylpyridin-2-amine
Source: Bos taurus. Cattle. Organism_taxid: 9913. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (405 residues) CATH domains: 3.90.340.10 3.90.440.10
4cu0
Structure of bovine endothelial nitric oxide synthase heme domain in complex with (r)-6-(3-amino-2-(5-(2-(6-amino-4- methylpyridin-2-yl)ethyl)pyridin-3-yl)propyl)-4- methylpyridin-2-amine
Source: Bos taurus. Cattle. Organism_taxid: 9913. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (405 residues) CATH domains: 3.90.340.10 3.90.440.10
4cu1
Structure of bovine endothelial nitric oxide synthase heme domain in complex with 6-[(2s)-3-amino-2-{5-[2-(6-amino- 4-methylpyridin-2-yl)ethyl]pyridin-3-yl}propyl]-4- methylpyridin-2-amine
Source: Bos taurus. Cattle. Organism_taxid: 9913. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (405 residues) CATH domains: 3.90.340.10 3.90.440.10
4cul
Structure of bovine endothelial nitric oxide synthase heme domain in complex with 6-acetyl-2-amino-7,7-dimethyl-7,8- dihydropteridin-4(3h)-one
Source: Bos taurus. Cattle. Organism_taxid: 9913. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (386 residues)
Bound ligand:   Het Group ARG corresponds to enzyme reactant L-arginine
4cum
Structure of bovine endothelial nitric oxide synthase heme domain in complex with (9as)-2-amino-9a-methyl-6,7,8,9,9a, 10-hexahydrobenzo[g]pteridin-4(3h)-one
Source: Bos taurus. Cattle. Organism_taxid: 9913. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (405 residues)
Bound ligand:   Het Group ARG corresponds to enzyme reactant L-arginine
4cun
Structure of bovine endothelial nitric oxide synthase heme domain in complex with (9as)-2-amino-9a-methyl-8,9,9a,10- tetrahydrobenzo[g]pteridine-4,6(3h,7h)-dione
Source: Bos taurus. Cattle. Organism_taxid: 9913. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (405 residues) CATH domains: 3.90.340.10 3.90.440.10
Bound ligand:   Het Group ARG corresponds to enzyme reactant L-arginine
4cvg
Structure of bovine endothelial nitric oxide synthase heme d (h4b-free) supplemented with 50um zn acetate and with poor of 6-acetyl-2-amino-7,7-dimethyl-7,8-dihydropteridin-4(3h)-
Source: Bos taurus. Cattle. Organism_taxid: 9913. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (403 residues)
Bound ligand:   Het Group ARG corresponds to enzyme reactant L-arginine
4cwv
Structure of bovine endothelial nitric oxide synthase heme domain in complex with 4-methyl-6-(((3r,4r)-4-((5-(pyridin- 2-yl)pentyl)oxy)pyrrolidin-3-yl)methyl)pyridin-2-amine
Source: Bos taurus. Cattle. Organism_taxid: 9913. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (404 residues)
4cww
Structure of bovine endothelial nitric oxide synthase heme domain in complex with 4-methyl-6-(((3r,4r)-4-((5-(4- methylpyridin-2-yl)pentyl)oxy)pyrrolidin-3-yl)methyl) pyridin-2-amine
Source: Bos taurus. Cattle. Organism_taxid: 9913. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (405 residues)
4cwx
Alpha-ketoglutarate-dependent dioxygenase complex1
Source: Bos taurus. Cattle. Organism_taxid: 9913. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (404 residues)
4cwy
Structure of bovine endothelial nitric oxide synthase heme domain in complex with 6-(5-(((3r,4r)-4-((6-amino-4- methylpyridin-2-yl)methyl)pyrrolidin-3-yl)oxy)pentyl)-4- methylpyridin-2-amine
Source: Bos taurus. Cattle. Organism_taxid: 9913. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (404 residues)
4cwz
Structure of bovine endothelial nitric oxide synthase y477a mutant heme domain in complex with 4-methyl-6-(((3r,4r)-4-( (5-(4-methylpyridin-2-yl)pentyl)oxy)pyrrolidin-3-yl)methyl) pyridin-2-amine
Source: Bos taurus. Cattle. Organism_taxid: 9913. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (405 residues)
4cx0
Structure of bovine endothelial nitric oxide synthase y477a mutant heme domain in complex with 6-((((3s, 5r)-5-(((6- amino-4-methylpyridin-2-yl)methoxy)methyl)pyrrolidin-3-yl) oxy)methyl)-4-methylpyridin-2-amine
Source: Bos taurus. Cattle. Organism_taxid: 9913. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (405 residues)
4cx1
Structure of bovine endothelial nitric oxide synthase l111a mutant heme domain in complex with 4-methyl-6-(((3r,4r)-4-( (5-(4-methylpyridin-2-yl)pentyl)oxy)pyrrolidin-3-yl)methyl) pyridin-2-amine
Source: Bos taurus. Cattle. Organism_taxid: 9913. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (405 residues)
4cx2
Structure of bovine endothelial nitric oxide synthase heme domain in complex with 6-(5-(((3r,4r)-4-((6-amino-4- methylpyridin-2-yl)methyl)pyrrolidin-3-yl)oxy)pentyl)-4- methylpyridin-2-amine
Source: Bos taurus. Cattle. Organism_taxid: 9913. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (405 residues)
4cx3
Structure of rat neuronal nitric oxide synthase m336v d597n mutant heme domain in complex with 4-methyl-6-(((3r,4r)-4-( (5-(pyridin-2-yl)pentyl)oxy)pyrrolidin-3-yl)methyl)pyridin- 2-amine
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (408 residues)
4cx4
Structure of rat neuronal nitric oxide synthase m336v d597n mutant heme domain in complex with 4-methyl-6-(((3r,4r)-4-( (5-(4-methylpyridin-2-yl)pentyl)oxy)pyrrolidin-3-yl)methyl) pyridin-2-amine
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (408 residues)
4cx5
Structure of rat neuronal nitric oxide synthase h341l mutant heme domain in complex with 4-methyl-6-(((3r,4r)-4-( (5-(pyridin-2-yl)pentyl)oxy)pyrrolidin-3-yl)methyl)pyridin- 2-amine
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (408 residues)
4cx6
Structure of rat neuronal nitric oxide synthase h341l mutant heme domain in complex with 6-((((3s, 5r)-5-(((6- amino-4-methylpyridin-2-yl)methoxy)methyl)pyrrolidin-3-yl) oxy)methyl)-4-methylpyridin-2-amine
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (408 residues)
4cx7
Structure of human inos heme domain in complex with (r)-6-( 3-amino-2-(5-(2-(6-amino-4- methylpyridin-2-yl)ethyl) pyridin-3-yl)propyl)-4-methylpyridin-2-amine
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D (414 residues)
4eux
Structure of neuronal nitric oxide synthase heme domain in c with 6-(5-(((3r,4r)-4-((6-amino-4-methylpyridin-2-yl)methyl pyrrolidin-3-yl)oxy)pentyl)-4-methylpyridin-2-amine
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
4fvw
Structure of rat nnos heme domain in complex with n(omega)-m arginine
Source: Rattus norvegicus. Brown rat,rat,rats. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
Bound ligand:   Het Group 1KJ is 85.71% similar to enzyme reactant L-arginine
4fvx
Structure of rat nnos heme domain in complex with n(omega)-e arginine
Source: Rattus norvegicus. Brown rat,rat,rats. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
Bound ligand:   Het Group 2KJ is 80.00% similar to enzyme reactant L-arginine
4fvy
Structure of rat nnos heme domain in complex with n(omega)-h n(omega)-methyl-l-arginine
Source: Rattus norvegicus. Brown rat,rat,rats. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
Bound ligand:   Het Group 3KJ is 85.71% similar to enzyme reactant L-arginine
4fvz
Structure of rat nnos heme domain in complex with n(omega)-m n(omega)-methoxy-l-arginine
Source: Rattus norvegicus. Brown rat,rat,rats. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
Bound ligand:   Het Group 4KJ is 80.00% similar to enzyme reactant L-arginine
4fw0
Structure of rat nnos heme domain in complex with n(delta)-m n(omega)-hydroxy-l-arginine
Source: Rattus norvegicus. Brown rat,rat,rats. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
Bound ligand:   Het Group 5KJ is 85.71% similar to enzyme reactant L-arginine
4gqe
Structure of rat neuronal nitric oxide synthase heme domain with (5e)-5-[(n-tert-butoxycarbamimidoyl)imino]-l-norvaline
Source: Rattus norvegicus. Brown rat,rat,rats. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
Bound ligand:   Het Group 6KJ is 70.59% similar to enzyme reactant L-arginine
4hop
Crystal structure of the computationally designed nnos-syntr complex
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: snt1, snta1. Expressed in: escherichia coli. Expression_system_taxid: 469008. Rattus norvegicus. Brown rat,rat,rats. Organism_taxid: 10116.
Chains: B, D, F (120 residues) CATH domain: 2.30.42.10
4ims
Structure of rat neuronal nitric oxide synthase heme domain with 6,6'-((5-(3-aminopropyl)-1,3-phenylene)bis(ethane-2,1- bis(4-methylpyridin-2-amine)
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
4imt
Structure of rat neuronal nitric oxide synthase in complex w ((4-(3-aminopropyl)-1,3-phenylene)bis(ethane-2,1-diyl))bis( methylpyridin-2-amine)
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
4imu
Structure of rat neuronal nitric oxide synthase in complex w ((5-(aminomethyl)-1,3-phenylene)bis(ethane-2,1-diyl))bis(4- methylpyridin-2-amine)
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
4imw
Structure of rat neuronal nitric oxide synthase in complex w bis(2-(6-amino-4-methylpyridin-2-yl)ethyl)benzonitrile
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
4imx
Structure of bovine endothelial nitric oxide synthase heme d complex with 3,5-bis(2-(6-amino-4-methylpyridin-2-yl)ethyl) benzonitrile
Source: Bos taurus. Bovine. Organism_taxid: 9913. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (405 residues) CATH domains: 3.90.340.10 3.90.440.10
4js9
Structural characterization of inducible nitric oxide syntha substituted with mesoheme
Source: Mus musculus. Mouse. Organism_taxid: 10090. Gene: inosl, nos2. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (405 residues) CATH domains: 3.90.340.10 3.90.440.10
4jse
Structure of rat neuronal nitric oxide synthase heme domain with 6,6'-(pentane-1,5-diyl)bis(4-methylpyridin-2-amine)
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (408 residues) CATH domains: 3.90.340.10 3.90.440.10
4jsf
Structure of rat neuronal nitric oxide synthase heme domain with 6,6'-(heptane-1,7-diyl)bis(4-methylpyridin-2-amine)
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
4jsg
Structure of rat neuronal nitric oxide synthase heme domain with 6-((3-(3-aminopropoxy)phenoxy)methyl)-4-methylpyridin-
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
4jsh
Structure of rat neuronal nitric oxide synthase heme domain with 4-methyl-6-((3-(piperidin-4-ylmethoxy)phenoxy)methyl)p amine
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (418 residues) CATH domains: 3.90.340.10 3.90.440.10
4jsi
Structure of rat neuronal nitric oxide synthase heme domain with 6-((3-(((3-fluorophenethyl)amino)methyl)phenoxy)methyl methylpyridin-2-amine
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
4jsj
Structure of rat neuronal nitric oxide synthase heme domain with 6-(((5-(((3-fluorophenethyl)amino)methyl)pyridin-3-yl) methyl)-4-methylpyridin-2-amine
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
4jsk
Structure of bovine endothelial nitric oxide synthase heme d complex with 6,6'-(pentane-1,5-diyl)bis(4-methylpyridin-2-a
Source: Bos taurus. Bovine. Organism_taxid: 9913. Gene: nos3. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (404 residues) CATH domains: 3.90.340.10 3.90.440.10
4jsl
Structure of bovine endothelial nitric oxide synthase heme d complex with 6,6'-(heptane-1,7-diyl)bis(4-methylpyridin-2-a
Source: Bos taurus. Bovine. Organism_taxid: 9913. Gene: nos3. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (405 residues) CATH domains: 3.90.340.10 3.90.440.10
4jsm
Structure of bovine endothelial nitric oxide synthase heme d complex with 6-(((5-(((3-fluorophenethyl)amino)methyl)pyrid oxy)methyl)-4-methylpyridin-2-amine
Source: Bos taurus. Bovine. Organism_taxid: 9913. Gene: nos3. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (406 residues) CATH domains: 3.90.340.10 3.90.440.10
4k5d
Structure of neuronal nitric oxide synthase heme domain in c with (s)-1,2-bis((2-amino-4-methylpyridin-6-yl)-methoxy)-pr amine
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
4k5e
Structure of neuronal nitric oxide synthase heme domain in c with (r)-1,2-bis((2-amino-4-methylpyridin-6-yl)-methoxy)-pr amine
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
4k5f
Structure of neuronal nitric oxide synthase heme domain in c with (s)-1,3-bis((2-amino-4-methylpyridin-6-yl)-methoxy)-bu amine
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
4k5g
Structure of neuronal nitric oxide synthase heme domain in c with ((2s, 3s)-1,3-bis((6-(2,5-dimethyl-1h-pyrrol-1-yl)-4- methylpyridin-2-yl)methoxy)-2-aminobutane
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
4k5h
Structure of bovine endothelial nitric oxide synthase heme d complex with (s)-1,2-bis((2-amino-4-methylpyridin-6-yl)-met propan-3-amine
Source: Bos taurus. Bovine. Organism_taxid: 9913. Gene: nos3. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (405 residues) CATH domains: 3.90.340.10 3.90.440.10
4k5i
Structure of bovine endothelial nitric oxide synthase heme d complex with (r)-1,2-bis((2-amino-4-methylpyridin-6-yl)-met propan-3-amine
Source: Bos taurus. Bovine. Organism_taxid: 9913. Gene: nos3. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (405 residues) CATH domains: 3.90.340.10 3.90.440.10
4k5j
Structure of bovine endothelial nitric oxide synthase heme d complex with (s)-1,3-bis((2-amino-4-methylpyridin-6-yl)-met butan-4-amine
Source: Bos taurus. Bovine. Organism_taxid: 9913. Gene: nos3. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (404 residues) CATH domains: 3.90.340.10 3.90.440.10
4k5k
Structure of bovine endothelial nitric oxide synthase heme d complex with ((2s, 3s)-1,3-bis((6-(2,5-dimethyl-1h-pyrrol-1 methylpyridin-2-yl)methoxy)-2-aminobutane
Source: Bos taurus. Bovine. Organism_taxid: 9913. Gene: nos3. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (405 residues) CATH domains: 3.90.340.10 3.90.440.10
4kch
Structure of neuronal nitric oxide synthase heme domain in c with n,n'-([1,1'-biphenyl]-3,3'-diyl)bis(thiophene-2-carbox
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
4kci
Structure of neuronal nitric oxide synthase heme domain in c with n,n'-(ethane-1,2-diylbis(3,1-phenylene))bis(thiophene- carboximidamide)
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
4kcj
Structure of neuronal nitric oxide synthase heme domain in c with n,n'-((ethane-1,2-diylbis(oxy))bis(3,1-phenylene))bis( 2-carboximidamide)
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
4kck
Structure of neuronal nitric oxide synthase heme domain in c with n-(3-(2-((3-(thiophene-2-carboximidamido)benzyl)amino) phenyl)thiophene-2-carboximidamide
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
4kcl
Structure of neuronal nitric oxide synthase heme domain in c with n-(4-(2-((3-(thiophene-2-carboximidamido)benzyl)amino) phenyl)thiophene-2-carboximidamide
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
4kcm
Structure of neuronal nitric oxide synthase heme domain in c with n-(4-(2-(ethyl(3-(thiophene-2-carboximidamido)benzyl)a ethyl)phenyl)thiophene-2-carboximidamide
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
4kcn
Structure of neuronal nitric oxide synthase heme domain in c with n-(3-(((3-fluorophenethyl)amino)methyl)phenyl)thiophen carboximidamide
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
4kco
Structure of neuronal nitric oxide synthase heme domain in c with n-(3-((ethyl(3-fluorophenethyl)amino)methyl)phenyl)thi carboximidamide
Source: Rattus norvegicus. Rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
4kcp
Structure of bovine endotheial nitric oxide synthase heme do complex with n-(4-(2-((3-(thiophene-2-carboximidamido)benzy ethyl)phenyl)thiophene-2-carboximidamide
Source: Bos taurus. Bovine. Organism_taxid: 9913. Gene: nos3. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (405 residues) CATH domains: 3.90.340.10 3.90.440.10
4kcq
Structure of bovine endothelial nitric oxide synthase heme d complex with n-(4-(2-(ethyl(3-(thiophene-2-carboximidamido) amino)ethyl)phenyl)thiophene-2-carboximidamide
Source: Bos taurus. Bovine. Organism_taxid: 9913. Gene: nos3. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (405 residues) CATH domains: 3.90.340.10 3.90.440.10
4kcr
Structure of bovine endothelial nitric oxide synthase heme d complex with n-(3-(((3-fluorophenethyl)amino)methyl)phenyl) 2-carboximidamide
Source: Bos taurus. Bovine. Organism_taxid: 9913. Gene: nos3. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (405 residues) CATH domains: 3.90.340.10 3.90.440.10
4kcs
Structure of bovine endothelial nitric oxide synthase heme d complex with n-(3-((ethyl(3-fluorophenethyl)amino)methyl)ph thiophene-2-carboximidamide
Source: Bos taurus. Bovine. Organism_taxid: 9913. Gene: nos3. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (405 residues) CATH domains: 3.90.340.10 3.90.440.10
4luw
Structure of bovine endothelial nitric oxide synthase heme d complex with 6-((((3r,5s)-5-(((6-amino-4-methylpyridin-2-yl methyl)pyrrolidin-3-yl)oxy)methyl)-4-methylpyridin-2-amine
Source: Bos taurus. Bovine. Organism_taxid: 9913. Gene: nos3. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (405 residues) CATH domains: 3.90.340.10 3.90.440.10
4lux
Structure of rat neuronal nitric oxide synthase heme domain with 6-((((3r,5s)-5-(((6-amino-4-methylpyridin-2-yl)methoxy pyrrolidin-3-yl)oxy)methyl)-4-methylpyridin-2-amine
Source: Rattus norvegicus. Brown rat. Organism_taxid: 10116. Gene: nos1, bnos. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (407 residues) CATH domains: 3.90.340.10 3.90.440.10
4nos
Human inducible nitric oxide synthase with inhibitor
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (421 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
4nse
Bovine endothelial nitric oxide synthase, h4b-free, l-arg co
Source: Bos taurus. Cattle. Organism_taxid: 9913. Cell: endothelial. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chains: A, B (416 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group ARG corresponds to enzyme reactant L-arginine
4upm
Structure of rat neuronal nitric oxide synthase heme domain in complex with n',n'-{[(2r)-3-aminopropane-1,2-diyl] bis(oxymethanediylbenzene-3,1-diyl)}dithiophene-2-carboximi
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (408 residues)
4upn
Structure of rat neuronal nitric oxide synthase heme domain in complex with n,n''-{[(2s)-3-aminopropane-1,2-diyl] bis(oxymethanediylbenzene-3,1-diyl)}dithiophene-2-carboximi
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (408 residues)
4upo
Structure of rat neuronal nitric oxide synthase heme domain in complex with n-[3-({[(3s,5s)-5-{[(3-{[(z)-imino(thiophen 2-yl)methyl]amino}benzyl)oxy]methyl}pyrrolidin-3-yl]oxy} methyl)phenyl]thiophene-2-carboximidamide
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (408 residues)
4upp
Structure of rat neuronal nitric oxide synthase heme domain in complex with n'-[4-[[(2s,4r)-4-[3-[(c-thiophen-2- ylcarbonimidoyl)amino]phenoxy]pyrrolidin-2- yl]methoxy]phenyl]thiophene-2-carboximidamide
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (408 residues)
4upq
Structure of bovine endothelial nitric oxide synthase heme domain in complex with n',n'-{[(2r)-3-aminopropane-1,2-diyl bis(oxymethanediylbenzene-3,1-diyl)}dithiophene-2-carboximi
Source: Bos taurus. Cattle. Organism_taxid: 9913. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (404 residues)
4upr
Structure of bovine endothelial nitric oxide synthase heme domain in complex with n,n''-{[(2s)-3-aminopropane-1,2-diyl bis(oxymethanediylbenzene-3,1-diyl)}dithiophene-2-carboximi
Source: Bos taurus. Cattle. Organism_taxid: 9913. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (405 residues)
4ups
Structure of bovine endothelial nitric oxide synthase heme domain in complex with n-[3-({[(3s,5s)-5-{[(3-{[(z)-imino (thiophen-2-yl)methyl]amino}benzyl)oxy]methyl}pyrrolidin-3 -yl]oxy}methyl)phenyl]thiophene-2-carboximidamide
Source: Bos taurus. Cattle. Organism_taxid: 9913. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (404 residues)
4upt
Structure of bovine endothelial nitric oxide synthase heme domain in complex with n'-[4-[[(2s,4r)-4-[3-[(c-thiophen-2- ylcarbonimidoyl)amino]phenoxy]pyrrolidin-2- yl]methoxy]phenyl]thiophene-2-carboximidamide
Source: Bos taurus. Cattle. Organism_taxid: 9913. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (405 residues)
5nse
Bovine endothelial nitric oxide synthase, h4b-free, hydroxy- complex
Source: Bos taurus. Cattle. Organism_taxid: 9913. Cell: endothelial. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chains: A, B (416 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group HAR is 92.31% similar to enzyme reactant L-arginine
6nse
Bovine endothelial nitric oxide synthase, h4b-free, canavani
Source: Bos taurus. Cattle. Organism_taxid: 9913. Cell: endothelial. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chains: A, B (416 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group GGB is 41.18% similar to enzyme reactant L-arginine
7nse
Bovine endothelial nitric oxide synthase, h4b-free, adma com
Source: Bos taurus. Cattle. Organism_taxid: 9913. Cell: endothelial. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chains: A, B (416 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group DA2 is 85.71% similar to enzyme reactant L-arginine
8nse
Bovine endothelial nitric oxide synthase, nna complex
Source: Bos taurus. Cattle. Organism_taxid: 9913. Cell: endothelial. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chains: A, B (416 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10
Bound ligand:   Het Group NRG is 80.00% similar to enzyme reactant L-arginine
9nse
Bovine endothelial nitric oxide synthase, ethyl-isoselenoure
Source: Bos taurus. Cattle. Organism_taxid: 9913. Cell: endothelial. Expressed in: escherichia coli bl21. Expression_system_taxid: 511693.
Chains: A, B (416 residues) CATH domains: 3.90.340.10 3.90.440.10 3.90.1230.10