_EC 1.14.13.132 Squalene monooxygenase. 0 PDB entries  
EC 1.-.-.- Oxidoreductases. [8,653 PDB entries]
EC 1.14.-.- Acting on paired donors, with incorporation or reduction of molecu [1,428 PDB entries]
EC 1.14.13.- With Nadh or nadph as one donor, and incorporation of one atom of [655 PDB entries]
EC 1.14.13.132 Squalene monooxygenase. [-]    

Reaction: Squalene + Nadph + O(2) = (3S)-2,3-epoxy-2,3-dihydrosqualene + NADP(+) + H(2)O.
 


Squalene
+
NADPH
+
O(2)
= (3S)-2,3-epoxy-2,3-dihydrosqualene
+
NADP(+)
+ H(2)O
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): Squalene epoxidase.
Cofactor(s): Fad.
 

FAD
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.
Comments: This enzyme, together with Ec 5.4.99.7, was formerly known as squalene oxidocyclase. The electron donor, Nadph, is coupled via ec 1.6.2.4. Formerly Ec 1.14.1.3, Ec 1.14.99.7 and Ec 1.99.1.13.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are no PDB entries in enzyme class E.C.1.14.13.132