_EC 1.14.13.104 (+)-menthofuran synthase. 0 PDB entries  
EC 1.-.-.- Oxidoreductases. [8,653 PDB entries]
EC 1.14.-.- Acting on paired donors, with incorporation or reduction of molecu [1,428 PDB entries]
EC 1.14.13.- With Nadh or nadph as one donor, and incorporation of one atom of [655 PDB entries]
EC 1.14.13.104 (+)-menthofuran synthase. [-]    

Reaction: (+)-pulegone + Nadph + O(2) = (+)-menthofuran + NADP(+) + H(2)O.
 


(+)-pulegone
+
NADPH
+
O(2)
=
(+)-menthofuran
+
NADP(+)
+ H(2)O
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): (+)-MFS. (+)-pulegone 9-hydroxylase. Menthofuran synthase.
Cofactor(s): Heme-thiolate.
Comments: The conversion of substrate into product involves the hydroxylation of the syn-methyl (C9), intramolecular cyclization to the hemiketal and dehydration to the furan. This is the second cytochrome P-450-mediated step of monoterpene metabolism in peppermint, with the other step being catalyzed by Ec 1.14.13.47.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are no PDB entries in enzyme class E.C.1.14.13.104