_EC 1.14.11.18 Phytanoyl-CoA dioxygenase. 1 PDB entries  
EC 1.-.-.- Oxidoreductases. [8,663 PDB entries]
EC 1.14.-.- Acting on paired donors, with incorporation or reduction of molecu [1,436 PDB entries]
EC 1.14.11.- With 2-oxoglutarate as one donor, and incorporation of one atom e [168 PDB entries]
EC 1.14.11.18 Phytanoyl-CoA dioxygenase. [1 PDB entries]    
2a1x

Reaction: Phytanoyl-CoA + 2-oxoglutarate + O(2) = 2-hydroxyphytanoyl-CoA + succinate + CO(2).
 


Phytanoyl-CoA
+
2-oxoglutarate
+
O(2)
=
2-hydroxyphytanoyl-CoA
+
succinate
+
CO(2)
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): Phytanoyl-CoA 2 oxoglutarate dioxygenase. Phytanoyl-CoA 2-hydroxylase. Phytanoyl-CoA alpha-hydroxylase. Phytanoyl-CoA hydroxylase.
Cofactor(s): Fe(2+); L-ascorbate.
 
Fe(2+)

L-ascorbate
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.
Comments: Part of the peroxisomal phytanic acid alpha-oxidation pathway.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 1 PDB entries in enzyme class E.C.1.14.11.18

  PDB code Protein
2a1x
Human phytanoyl-coa 2-hydroxylase in complex with iron and 2 oxoglutarate
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: phyh, pahx. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (253 residues)
Bound ligand:   Het Group AKG corresponds to enzyme reactant 2-oxoglutarate