_EC 1.1.5.3 Glycerol-3-phosphate dehydrogenase. 6 PDB entries  
EC 1.-.-.- Oxidoreductases. [9,199 PDB entries]
EC 1.1.-.- Acting on the CH-OH group of donors. [1,958 PDB entries]
EC 1.1.5.- With a quinone or similar compound as acceptor. [12 PDB entries]
EC 1.1.5.3 Glycerol-3-phosphate dehydrogenase. [6 PDB entries]    
2qcu

Reaction: sn-glycerol 3-phosphate + a quinone = glycerone phosphate + a quinol.
 


sn-glycerol 3-phosphate
+
quinone
=
glycerone phosphate
+ quinol
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): FAD-dependent glycerol-3-phosphate dehydrogenase. Flavin-linked glycerol-3-phosphate dehydrogenase. Glycerol-3-phosphate CoQ reductase. Glycerophosphate dehydrogenase. L-glycerophosphate dehydrogenase. sn-glycerol-3-phosphate dehydrogenase.
Cofactor(s): Flavin.
 

Flavin
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.
Comments: An essential membrane enzyme, functioning at the central junction of glycolysis, respiration and phospholipid biosynthesis. In bacteria, the enzyme is localized to the cytoplasmic membrane, while in eukaryotes it is tightly bound to the outer surface of the inner mitochondrial membrane. In eukaryotes, this enzyme, together with the cytosolic enzyme Ec 1.1.1.8 forms the glycerol-3-phosphate shuttle by which Nadh produced in the cytosol, primarily from glycolysis, can be reoxidized to NAD(+) by the mitochondrial electron-transport chain. This shuttle plays a critical role in transferring reducing
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 6 PDB entries in enzyme class E.C.1.1.5.3

  PDB code Protein
2qcu
Crystal structure of glycerol-3-phosphate dehydrogenase from escherichia coli
Source: Escherichia coli. Organism_taxid: 562. Gene: glpd, glyd. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (499 residues) CATH domains: 3.50.50.60 3.30.9.10
Bound ligands:   Het Group PO4 is 50.00% similar to enzyme reactant sn-glycerol 3-phosphate
  Het Group BOG is 40.00% similar to enzyme reactant quinone
2r45
Crystal structure of escherichia coli glycerol-3-phosphate dehydrogenase in complex with 2-phospho-d-glyceric acid
Source: Escherichia coli. Organism_taxid: 562. Gene: glpd. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (495 residues) CATH domains: 3.50.50.60 3.30.9.10
Bound ligands:   Het Group 2PG is 61.00% similar to enzyme reactant sn-glycerol 3-phosphate
  Het Group BOG is 40.00% similar to enzyme reactant quinone
2r46
Crystal structure of escherichia coli glycerol-3-phosphate dehydrogenase in complex with 2-phosphopyruvic acid.
Source: Escherichia coli. Organism_taxid: 562. Gene: glpd, glyd. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (495 residues) CATH domains: 3.50.50.60 3.30.9.10
Bound ligands:   Het Group PEP is 66.00% similar to enzyme reactant sn-glycerol 3-phosphate
  Het Group BOG is 40.00% similar to enzyme reactant quinone
2r4e
Crystal structure of escherichia coli glycerol-3-phosphate dehydrogenase in complex with dhap
Source: Escherichia coli. Organism_taxid: 562. Gene: glpd, glyd. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (494 residues) CATH domains: 3.50.50.60 3.30.9.10
Bound ligands:   Het Group 13P corresponds to enzyme reactant sn-glycerol 3-phosphate
  Het Group BOG is 40.00% similar to enzyme reactant quinone
2r4j
Crystal structure of escherichia coli semet substituted glycerol-3-phosphate dehydrogenase in complex with dhap
Source: Escherichia coli. Gene: glpd, glyd. Expressed in: escherichia coli
Chains: A, B (494 residues) CATH domains: 3.50.50.60 3.30.9.10
Bound ligands:   Het Group 13P corresponds to enzyme reactant sn-glycerol 3-phosphate
  Het Group BOG is 40.00% similar to enzyme reactant quinone
3da1
X-ray structure of the glycerol-3-phosphate dehydrogenase from bacillus halodurans complexed with fad. Northeast structural genomics consortium target bhr167.
Source: Bacillus halodurans
Chain: A (496 residues) CATH domain: 3.50.50.60