_EC 1.1.1.8 Glycerol-3-phosphate dehydrogenase (NAD(+)). 13 PDB entries  
EC 1.-.-.- Oxidoreductases. [8,663 PDB entries]
EC 1.1.-.- Acting on the CH-OH group of donors. [1,873 PDB entries]
EC 1.1.1.- With NAD(+) or NADP(+) as acceptor. [1,684 PDB entries]
EC 1.1.1.8 Glycerol-3-phosphate dehydrogenase (NAD(+)). [13 PDB entries]    
1evy

Reaction: sn-glycerol 3-phosphate + NAD(+) = glycerone phosphate + Nadh.
 


sn-glycerol 3-phosphate
+
NAD(+)
=
glycerone phosphate
+
NADH
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): Alpha-glycerol phosphate dehydrogenase (NAD). Alpha-glycerophosphate dehydrogenase (NAD). Glycerol 1-phosphate dehydrogenase. Glycerol phosphate dehydrogenase (NAD). Glycerol-3-phosphate dehydrogenase (NAD). Glycerophosphate dehydrogenase (NAD). Hydroglycerophosphate dehydrogenase. L-alpha-glycerol phosphate dehydrogenase. L-alpha-glycerophosphate dehydrogenase. L-glycerol phosphate dehydrogenase.
Comments: Also acts on propane-1,2-diol phosphate and glycerone sulfate (but with a much lower affinity).
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 13 PDB entries in enzyme class E.C.1.1.1.8

  PDB code Protein
1evy
Crystal structure of leishmania mexicana glycerol-3-phosphat dehydrogenase
Source: Leishmania mexicana. Organism_taxid: 5665. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (346 residues) CATH domains: 3.40.50.720 1.10.1040.10
1evz
Crystal structure of leishmania mexicana glycerol-3-phosphat dehydrogenase in complex with NAD
Source: Leishmania mexicana. Organism_taxid: 5665. Cellular_location: glycosome. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (346 residues) CATH domains: 3.40.50.720 1.10.1040.10
Bound ligand:   Het Group NAD corresponds to enzyme reactant NAD(+)
1jdj
Crystal structure of leishmania mexicana glycerol-3-phosphat dehydrogenase in complex with 2-fluoro-6-chloropurine
Source: Leishmania mexicana. Organism_taxid: 5665. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (346 residues) CATH domains: 3.40.50.720 1.10.1040.10
1m66
Crystal structure of leishmania mexicana gpdh complexed with 2-bromo-6-chloro-purine
Source: Leishmania mexicana. Organism_taxid: 5665. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (346 residues) CATH domains: 3.40.50.720 1.10.1040.10
1m67
Crystal structure of leishmania mexicana gpdh complexed with 2-bromo-6-hydroxy-purine
Source: Leishmania mexicana. Organism_taxid: 5665. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (346 residues) CATH domains: 3.40.50.720 1.10.1040.10
1n1e
Crystal structure of leishmania mexicana glycerol-3- phosphate dehydrogenase complexed with dhap and NAD
Source: Leishmania mexicana. Organism_taxid: 5665. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (349 residues) CATH domains: 3.40.50.720 1.10.1040.10
Bound ligand:   Het Group NDE is 81.00% similar to enzyme reactant NAD(+)
1n1g
Crystal structure of leishmania mexicana glycerol-3-phosphat dehydrogenase with inhibitor bcp
Source: Leishmania mexicana. Organism_taxid: 5665. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (346 residues) CATH domains: 3.40.50.720 1.10.1040.10
1wpq
Ternary complex of glycerol 3-phosphate dehydrogenase 1 with NAD and dihydroxyactone
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (348 residues) CATH domains: 3.40.50.720 1.10.1040.10
Bound ligands:   Het Group 13P corresponds to enzyme reactant sn-glycerol 3-phosphate
  Het Group NAD corresponds to enzyme reactant NAD(+)
1x0v
Crystal structure of homo sapien glycerol-3-phosphate dehydrogenase 1
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (348 residues) CATH domains: 3.40.50.720 1.10.1040.10
1x0x
Co-structure of homo sapiens glycerol-3-phosphate dehydrogen complex with NAD
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (350 residues) CATH domains: 3.40.50.720 1.10.1040.10
Bound ligand:   Het Group NAD corresponds to enzyme reactant NAD(+)
1yj8
Initial structural analysis of plasmodium falciparum glycero phosphate dehydrogenase
Source: Plasmodium falciparum. Organism_taxid: 36329. Strain: 3d7. Gene: pfl0780w. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C (357 residues) CATH domains: 3.40.50.720 1.10.1040.10
2pla
Crystal structure of human glycerol-3-phosphate dehydrogenas protein
Source: Homo sapiens. Human. Organism_taxid: 9606. Tissue: brain. Gene: gpd1l. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (343 residues) CATH domains: 3.40.50.720 1.10.1040.10
Bound ligands:   Het Group PO4 is 50.00% similar to enzyme reactant sn-glycerol
  Het Group NAD corresponds to enzyme reactant NAD(+)
4fgw
Structure of glycerol-3-phosphate dehydrogenase, gpd1, from sacharomyces cerevisiae
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: gpd1, dar1, hor1, osg1, ydl022w, d2830. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (353 residues) CATH domains: 3.40.50.720 1.10.1040.10