_EC 1.1.1.141 15-hydroxyprostaglandin dehydrogenase (NAD(+)). 1 PDB entries  
EC 1.-.-.- Oxidoreductases. [8,653 PDB entries]
EC 1.1.-.- Acting on the CH-OH group of donors. [1,874 PDB entries]
EC 1.1.1.- With NAD(+) or NADP(+) as acceptor. [1,685 PDB entries]
EC 1.1.1.141 15-hydroxyprostaglandin dehydrogenase (NAD(+)). [1 PDB entries]    
2gdz

Reaction: (5Z,13E,15S)-11-alpha,15-dihydroxy-9-oxoprost-5,13-dienoate + NAD(+) = (5Z,13E)-11-alpha-hydroxy-9,15-dioxoprost-5,13-dienoate + Nadh.
 

(5Z,13E,15S)-11-alpha,15-dihydroxy-9-oxoprost-5,13-dienoate
+
NAD(+)
= (5Z,13E)-11-alpha-hydroxy-9,15-dioxoprost-5,13-dienoate
+
NADH
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Other name(s): 15-hydroxyprostaglandin dehydrogenase.
Comments: Acts on prostaglandins E(2), F(2-alpha) and B(1), but not on prostaglandin D(2) (cf. Ec 1.1.1.196 and Ec 1.1.1.197).
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 1 PDB entries in enzyme class E.C.1.1.1.141

  PDB code Protein
2gdz
Crystal structure of 15-hydroxyprostaglandin dehydrogenase t complexed with NAD+
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (266 residues) CATH domain: 3.40.50.720
Bound ligand:   Het Group NAD corresponds to enzyme reactant NAD(+)