_EC 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase. 95 PDB entries  
EC 1.-.-.- Oxidoreductases. [8,663 PDB entries]
EC 1.1.-.- Acting on the CH-OH group of donors. [1,873 PDB entries]
EC 1.1.1.- With NAD(+) or NADP(+) as acceptor. [1,684 PDB entries]
EC 1.1.1.100 3-oxoacyl-[acyl-carrier-protein] reductase. [95 PDB entries]    
1edo

Reaction: (3R)-3-hydroxyacyl-[acyl-carrier-protein] + NADP(+) = 3-oxoacyl-[acyl- carrier-protein] + Nadph.
 


(3R)-3-hydroxyacyl-[acyl-carrier-protein]
+
NADP(+)
=
3-oxoacyl-[acyl- carrier-protein]
+
NADPH
Molecule diagrams generated from .mol files obtained from the KEGG ftp site.

Comments: Exhibits a marked preference for [acyl-carrier-protein] derivatives over CoA derivatives as substrates.
Links:   [IntEnz]   [ExPASy]   [KEGG]  

There are 95 PDB entries in enzyme class E.C.1.1.1.100

  PDB code Protein
1edo
The x-ray structure of beta-keto acyl carrier protein reduct brassica napus complexed with NADP+
Source: Brassica napus. Rape. Organism_taxid: 3708. Gene: oil seed rape. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (244 residues) CATH domain: 3.40.50.720
Bound ligand:   Het Group NAP corresponds to enzyme reactant NADP(+)
1i01
Crystal structure of beta-ketoacyl [acyl carrier protein] reductase from e. Coli.
Source: Escherichia coli. Organism_taxid: 562. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D, E, F, G, H (228 residues) CATH domain: 3.40.50.720
1o5i
Crystal structure of 3-oxoacyl-(acyl carrier protein) reduct (tm1169) from thermotoga maritima at 2.50 a resolution
Source: Thermotoga maritima. Organism_taxid: 2336. Gene: tm1169. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (234 residues) CATH domain: 3.40.50.720
1q7b
The structure of betaketoacyl-[acp] reductase from e. Coli in complex with NADP+
Source: Escherichia coli. Organism_taxid: 562. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (243 residues) CATH domain: 3.40.50.720
Bound ligand:   Het Group NAP corresponds to enzyme reactant NADP(+)
1q7c
The structure of betaketoacyl-[acp] reductase y151f mutant i with NADPH fragment
Source: Escherichia coli. Organism_taxid: 562. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (243 residues) CATH domain: 3.40.50.720
Bound ligand:   Het Group NAP is 64.00% similar to enzyme reactant NADP(+)
1uzl
Maba from mycobacterium tuberculosis
Source: Mycobacterium tuberculosis. Organism_taxid: 1773. Strain: rv37. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (231 residues) CATH domain: 3.40.50.720
1uzm
Maba from mycobacterium tuberculosis
Source: Mycobacterium tuberculosis. Organism_taxid: 83332. Strain: h37rv. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (227 residues) CATH domain: 3.40.50.720
1uzn
Maba from mycobacterium tuberculosis
Source: Mycobacterium tuberculosis. Organism_taxid: 83332. Strain: h37rv. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (239 residues) CATH domain: 3.40.50.720
Bound ligand:   Het Group NAP is 62.00% similar to enzyme reactant NADP(+)
1xkt
Human fatty acid synthase: structure and substrate selectivity of the thioesterase domain
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (260 residues) CATH domains: 3.40.50.1820 1.10.1470.20
2a4k
3-oxoacyl-[acyl carrier protein] reductase from thermus ther tt0137
Source: Thermus thermophilus. Organism_taxid: 274
Chain: A (237 residues) CATH domain: 3.40.50.720
2b4q
Pseudomonas aeruginosa rhlg/NADP active-site complex
Source: Pseudomonas aeruginosa. Organism_taxid: 287. Gene: rhlg. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (256 residues) CATH domain: 3.40.50.720
Bound ligand:   Het Group NAP corresponds to enzyme reactant NADP(+)
2c07
Oxoacyl-acp reductase of plasmodium falciparum
Source: Plasmodium falciparum. Malaria parasite. Organism_taxid: 36329. Strain: 3d7. Expressed in: escherichia coli. Expression_system_taxid: 511693. Expression_system_variant: codon plus ril.
Chain: A (246 residues) CATH domain: 3.40.50.720
2cg5
Structure of aminoadipate-semialdehyde dehydrogenase- phosphopantetheinyl transferase in complex with cytosolic acyl carrier protein and coenzyme a
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 511693. Expression_system_cell_line: de3. Expressed in: escherichia coli
Chain: B (71 residues) CATH domain: 1.10.1200.10
Bound ligand:   Het Group COA is 59.00% similar to enzyme reactant NADP(+)
2jfd
Structure of the mat domain of human fas
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 511693. Expression_system_cell_line: de3-r3.
Chains: A, B, C, D (404 residues) CATH domains: Unassigned 3.40.366.10 3.30.70.250
2jfk
Structure of the mat domain of human fas with malonyl-coa
Source: Homo sapiens. Human. Organism_taxid: 9606. Expressed in: escherichia coli. Expression_system_taxid: 511693. Expression_system_cell_line: de3-r3.
Chains: A, B, C, D (401 residues) CATH domains: Unassigned 3.40.366.10 3.30.70.250
2ntn
Crystal structure of maba-c60v/g139a/s144l
Source: Mycobacterium tuberculosis h37rv. Organism_taxid: 83332. Strain: h37rv. Gene: fabg, fabg1. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chains: A, B (218 residues) CATH domain: 3.40.50.720
2p68
Crystal structure of aq_1716 from aquifex aeolicus vf5
Source: Aquifex aeolicus. Organism_taxid: 224324. Strain: vf5. Gene: fabg, aq_1716. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (248 residues) CATH domain: 3.40.50.720
2pff
Structural insights of yeast fatty acid synthase
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Strain: yit613. Synthetic: yes
Chains: A, D, G (1683 residues)
2pnf
Structure of aquifex aeolicus fabg 3-oxoacyl-(acyl-carrier p reductase
Source: Aquifex aeolicus. Organism_taxid: 224324. Strain: vf5. Gene: fabg. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (248 residues) CATH domain: 3.40.50.720
2png
Type i rat fatty acid synthase acyl carrier protein (acp) domain
Source: Rattus norvegicus. Norway rat. Organism_taxid: 10116. Gene: fasn. Expressed in: escherichia coli bl21(de3). Expression_system_taxid: 469008.
Chain: A (89 residues) CATH domain: 1.10.1200.10
2px6
Crystal structure of the thioesterase domain of human fatty acid synthase inhibited by orlistat
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fas. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (253 residues) CATH domains: 3.40.50.1820 1.10.1470.20
Bound ligand:   Het Group DTT is 45.00% similar to enzyme reactant (3R)-3-hydroxyacyl-[acyl-carrier-protein]
2uv8
Crystal structure of yeast fatty acid synthase with stalled acyl carrier protein at 3.1 angstrom resolution
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Organism_taxid: 4932
Chains: A, B, C (1614 residues) CATH domains: Unassigned Unassigned Unassigned Unassigned Unassigned Unassigned Unassigned
2uvd
The crystal structure of a 3-oxoacyl-(acyl carrier protein) reductase from bacillus anthracis (ba3989)
Source: Bacillus anthracis. Organism_taxid: 198094. Strain: ames. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D, E, F, G, H (246 residues) CATH domain: 3.40.50.720
2vkz
Structure of the cerulenin-inhibited fungal fatty acid synthase type i multienzyme complex
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Organism_taxid: 4932
Chains: A, B, C (1614 residues)
2was
Structure of the fungal type i fas ppt domain
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: gold.
Chains: A, B, C, D, E, F (113 residues) CATH domain: 3.90.470.20
2wat
Structure of the fungal type i fas ppt domain in complex with coa
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Expressed in: escherichia coli. Expression_system_taxid: 469008. Expression_system_variant: gold.
Chains: A, B, C, D, E, F (121 residues) CATH domain: 3.90.470.20
Bound ligand:   Het Group COA is 52.00% similar to enzyme reactant NADP(+)
3emk
2.5a crystal structure of glucose/ribitol dehydrogenase from brucella melitensis
Source: Brucella melitensis. Organism_taxid: 29459. Strain: biovar abortus 2308. Gene: bmei1477. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (241 residues) CATH domain: 3.40.50.720
3enn
2.1a crystal structure of glucose/ribitol dehydrogenase from melitensis (p43212)
Source: Brucella melitensis. Organism_taxid: 29459. Strain: biovar abortus 2308. Gene: bmei1477, brucella melitensis. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (238 residues) CATH domain: 3.40.50.720
3f9i
Crystal structure of 3-ketoacyl-(acyl-carrier-protein) reduc rickettsia prowazekii
Source: Rickettsia prowazekii. Organism_taxid: 782. Gene: fabg, rp762. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (220 residues) CATH domain: 3.40.50.720
3ftp
Crystal structure of 3-ketoacyl-(acyl-carrier-protein) reduc burkholderia pseudomallei at 2.05 a resolution
Source: Burkholderia pseudomallei. Pseudomonas pseudomallei. Organism_taxid: 28450. Strain: 1710b. Gene: fabg, bpsl2440. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (248 residues) CATH domain: 3.40.50.720
3hhd
Structure of the human fatty acid synthase ks-mat didomain as a framework for inhibitor design.
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fasn, fas. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108
Chains: A, B, C, D (852 residues) CATH domains: Unassigned Unassigned Unassigned 3.30.70.250
3hmj
Saccharomyces cerevisiae fas type i
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 4932. Gene: fas2. Gene: fas1
Chains: A, B, C (1750 residues)
3lyl
Structure of 3-oxoacyl-acylcarrier protein reductase, fabg from francisella tularensis
Source: Francisella tularensis subsp. Tularensis. Organism_taxid: 177416. Strain: schu s4. Gene: fabg, ftt1375, ftt_1375. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (247 residues) CATH domain: 3.40.50.720
3m1l
Crystal strucutre of a c-terminal trunacted mutant of a puta ketoacyl reductase (fabg4) from mycobacterium tuberculosis 2.5 angstrom resolution
Source: Mycobacterium tuberculosis. Organism_taxid: 83332. Strain: h37rv. Gene: rv0242c. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (364 residues) CATH domains: Unassigned 3.40.50.720
3o38
Crystal structure of a short chain dehydrogenase from mycoba smegmatis
Source: Mycobacterium smegmatis. Organism_taxid: 246196. Strain: atcc 700084 / mc(2)155. Gene: msmeg_6011. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (244 residues) CATH domain: 3.40.50.720
3op4
Crystal structure of putative 3-ketoacyl-(acyl-carrier-prote reductase from vibrio cholerae o1 biovar eltor str. N16961 with NADP+
Source: Vibrio cholerae o1 biovar el tor. Organism_taxid: 243277. Strain: n16961. Gene: vcd_002346. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (247 residues) CATH domain: 3.40.50.720
Bound ligand:   Het Group NAP corresponds to enzyme reactant NADP(+)
3osu
Crystal structure of the 3-oxoacyl-acyl carrier protein redu fabg, from staphylococcus aureus
Source: Staphylococcus aureus subsp. Aureus mu organism_taxid: 158878. Strain: subsp. Aureus mu50. Gene: fabg, sav1231. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (246 residues) CATH domain: 3.40.50.720
3q6i
Crystal structure of fabg4 and coenzyme binary complex
Source: Mycobacterium tuberculosis. Organism_taxid: 83332. Strain: h37rv. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (427 residues) CATH domains: Unassigned 3.40.50.720
3rro
Crystal structure of 3-ketoacyl-(acyl-carrier-protein) reduc (fabg) from vibrio cholerae
Source: Vibrio cholerae o1 biovar el tor. Organism_taxid: 243277. Strain: n16961. Gene: vcd_002346. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (247 residues) CATH domain: 3.40.50.720
Bound ligand:   Het Group GOL is 55.56% similar to enzyme reactant (3R)-3-hydroxyacyl-[acyl-carrier-protein]
3rsh
Structure of 3-ketoacyl-(acyl-carrier-protein)reductase (fab vibrio cholerae o1 complexed with NADP+ (space group p62)
Source: Vibrio cholerae o1 biovar el tor. Organism_taxid: 243277. Strain: n16961. Gene: vcd_002346. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (244 residues) CATH domain: 3.40.50.720
Bound ligand:   Het Group NAP corresponds to enzyme reactant NADP(+)
3sj7
Structure of beta-ketoacetyl-coa reductase (fabg) from staph aureus complex with NADPH
Source: Staphylococcus aureus subsp. Aureus. Organism_taxid: 93061. Strain: nctc 8325. Gene: saouhsc_01199. Expressed in: escherichia coli. Expression_system_taxid: 1007065.
Chains: A, B (239 residues) CATH domain: 3.40.50.720
3tjm
Crystal structure of the human fatty acid synthase thioester with an activate site-specific polyunsaturated fatty acyl a
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fas, fasn. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (275 residues) CATH domains: 3.40.50.1820 1.10.1470.20
3tzc
Crystal structure of 3-ketoacyl-(acyl-carrier-protein) reduc (fabg)(y155f) from vibrio cholerae
Source: Vibrio cholerae. Organism_taxid: 593588. Strain: mj-1236. Gene: vc2021, vcd_002346. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (224 residues) CATH domain: 3.40.50.720
3tzh
Crystal structure of 3-ketoacyl-(acyl-carrier-protein) reduc (fabg)(f187a) from vibrio cholerae
Source: Vibrio cholerae. Organism_taxid: 593588. Strain: mj-1236. Gene: vc2021, vcd_002346. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D, E, F (247 residues) CATH domain: 3.40.50.720
Bound ligand:   Het Group GOL is 55.56% similar to enzyme reactant (3R)-3-hydroxyacyl-[acyl-carrier-protein]
3tzk
Crystal structure of 3-ketoacyl-(acyl-carrier-protein) reduc (fabg)(g92a) from vibrio cholerae
Source: Vibrio cholerae. Organism_taxid: 593588. Strain: mj-1236. Gene: vc2021, vcd_002346. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (247 residues) CATH domain: 3.40.50.720
3u09
Crystal structure of 3-ketoacyl-(acyl-carrier-protein) reduc (fabg)(g92d) from vibrio cholerae
Source: Vibrio cholerae. Organism_taxid: 243277. Strain: o1 biovar eltor str. N16961. Gene: fabg, vc2021, vc_2021. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B (248 residues) CATH domain: 3.40.50.720
3u0b
Crystal structure of an oxidoreductase from mycobacterium sm
Source: Mycobacterium smegmatis. Organism_taxid: 246196. Strain: atcc 700084 / mc(2)155. Gene: msmeg_0372. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (415 residues) CATH domains: Unassigned 3.40.50.720
3u5t
The crystal structure of 3-oxoacyl-[acyl-carrier-protein] re from sinorhizobium meliloti
Source: Sinorhizobium meliloti. Ensifer meliloti. Organism_taxid: 382. Gene: rb0475, sm_b20493. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D (230 residues) CATH domain: 3.40.50.720
3u9l
The crystal structure of 3-oxoacyl-[acyl-carrier-protein] re (NADPH) from sinorhizobium meliloti
Source: Sinorhizobium meliloti. Ensifer meliloti. Organism_taxid: 382. Gene: rb0474, sm_b20492. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (286 residues) CATH domain: 3.40.50.720
3un1
Crystal structure of an oxidoreductase from sinorhizobium me 1021
Source: Sinorhizobium meliloti. Organism_taxid: 382. Strain: 1021. Gene: y20210, rb0203, sm_b20210. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D (241 residues) CATH domain: 3.40.50.720
3v1t
Crystal structure of a putative ketoacyl reductase (fabg4) f mycobacterium tuberculosis h37rv at 1.9 angstrom resolution
Source: Mycobacterium tuberculosis. Organism_taxid: 83332. Strain: h37rv. Gene: fabg-1, fabg4, mt0256, rv0242c. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: C, D (407 residues) CATH domains: Unassigned 3.40.50.720
3v1u
Crystal structure of a beta-ketoacyl reductase fabg4 from mycobacterium tuberculosis h37rv complexed with NAD+ and he at 2.5 angstrom resolution
Source: Mycobacterium tuberculosis. Organism_taxid: 83332. Strain: h37rv. Gene: fabg-1, fabg4, mt0256, rv0242c. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (416 residues) CATH domains: Unassigned 3.40.50.720
3v2g
Crystal structure of a dehydrogenase/reductase from sinorhiz meliloti 1021
Source: Sinorhizobium meliloti. Organism_taxid: 266834. Strain: 1021. Gene: rb0438, sm_b20456. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chain: A (252 residues) CATH domain: 3.40.50.720
3v8b
Crystal structure of a 3-ketoacyl-acp reductase from sinorhi meliloti 1021
Source: Sinorhizobium meliloti. Organism_taxid: 266834. Strain: 1021. Gene: rb1300, sm_b21474. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D (257 residues) CATH domain: 3.40.50.720
4afn
Crystal structure of 3-ketoacyl-(acyl-carrier-protein) reduc (fabg) from pseudomonas aeruginosa at 2.3a resolution
Source: Pseudomonas aeruginosa. Organism_taxid: 208964. Strain: pao1. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D (253 residues) CATH domain: 3.40.50.720
4ag3
Crystal structure of 3-ketoacyl-(acyl-carrier-protein) reductase (fabg) from pseudomonas aeruginosa in complex with NADPH at 1.8a resolution
Source: Pseudomonas aeruginosa. Organism_taxid: 208964. Strain: pao1. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D (254 residues) CATH domain: 3.40.50.720
4bnt
Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reduct (fabg) from pseudomonas aeruginosa in complex with 2-(trifluoromethyl)-1h-benzimidazole at 2.3a resolution
Source: Pseudomonas aeruginosa. Organism_taxid: 208964. Strain: pao1. Atcc: 47085. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D (240 residues) CATH domain: 3.40.50.720
4bnu
Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (fabg) from pseudomonas aeruginosa in complex with 2-phenyl-4-(1,2,4-triazol-4-yl)quinazoline at 2.0a resolution
Source: Pseudomonas aeruginosa. Organism_taxid: 208964. Strain: pao1. Atcc: 47085. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D (239 residues) CATH domain: 3.40.50.720
4bnv
Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (fabg) from pseudomonas aeruginosa in complex with 1-(2-chlorophenyl)-3-(1-methylbenzimidazol-2-yl)urea at 2.5a resolution
Source: Pseudomonas aeruginosa. Organism_taxid: 208964. Strain: pao1. Atcc: 47085. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D (230 residues) CATH domain: 3.40.50.720
4bnw
Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (fabg) from pseudomonas aeruginosa in complex with an unknown ligand at 1.6a resolution
Source: Pseudomonas aeruginosa. Organism_taxid: 208964. Strain: pao1. Atcc: 47085. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D (242 residues) CATH domain: 3.40.50.720
4bnx
Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (fabg) from pseudomonas aeruginosa in complex with 6-(4-(2-chloroanilino)-1h-quinazolin-2-ylidene) cyclohexa-2, 4-dien-1-one at 2.3a resolution
Source: Pseudomonas aeruginosa. Organism_taxid: 208964. Strain: pao1. Atcc: 47085. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D (239 residues) CATH domain: 3.40.50.720
4bny
Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reduct (fabg) from pseudomonas aeruginosa in complex with 4-(2-phenylthieno(3,2-d)pyrimidin-4-yl)morpholine at 1.8a r
Source: Pseudomonas aeruginosa. Organism_taxid: 208964. Strain: pao1. Atcc: 47085. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D (239 residues) CATH domain: 3.40.50.720
4bnz
Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (fabg) from pseudomonas aeruginosa in complex with 1-methyl-n-phenylindole-3-carboxamide at 2.5a resolution
Source: Pseudomonas aeruginosa. Organism_taxid: 208964. Strain: pao1. Atcc: 47085. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D (241 residues) CATH domain: 3.40.50.720
4bo0
Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (fabg) from pseudomonas aeruginosa in complex with 1-(4-methoxy-1-methylindazol-3-yl)-3-(2-methoxyphenyl) urea at 2.4a resolution
Source: Pseudomonas aeruginosa. Organism_taxid: 208964. Strain: pao1. Atcc: 47085. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D (235 residues) CATH domain: 3.40.50.720
4bo1
Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (fabg) from pseudomonas aeruginosa in complex with n-(4-chloro-2,5-dimethoxyphenyl)quinoline-8- carboxamide at 2.2a resolution
Source: Pseudomonas aeruginosa. Organism_taxid: 208964. Strain: pao1. Atcc: 47085. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D (237 residues) CATH domain: 3.40.50.720
4bo2
Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reduct fabg) from pseudomonas aeruginosa in complex with 1-(1-ethylbenzimidazol-2-yl)-3-(2-methoxyphenyl)urea at 1.9a resolution
Source: Pseudomonas aeruginosa. Organism_taxid: 208964. Strain: pao1. Atcc: 47085. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D (238 residues) CATH domain: 3.40.50.720
4bo3
Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (fabg) from pseudomonas aeruginosa in complex with 2-(3-(trifluoromethyl)anilino)pyridine-3-sulfonamide at 2.5a resolution
Source: Pseudomonas aeruginosa. Organism_taxid: 208964. Strain: pao1. Atcc: 47085. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D (233 residues) CATH domain: 3.40.50.720
4bo4
Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (fabg) from pseudomonas aeruginosa in complex with n-(2-methoxyphenyl)-3,4-dihydro-2h-quinoline-1- carboxamide at 2.7a resolution
Source: Pseudomonas aeruginosa. Organism_taxid: 208964. Strain: pao1. Atcc: 47085. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D (235 residues) CATH domain: 3.40.50.720
4bo5
Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (fabg) from pseudomonas aeruginosa in complex with n-(2-chlorophenyl)-4-pyrrol-1-yl-1,3,5-triazin-2- amine at 2.6a resolution
Source: Pseudomonas aeruginosa. Organism_taxid: 208964. Strain: pao1. Atcc: 47085. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D (236 residues) CATH domain: 3.40.50.720
4bo6
Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (fabg) from pseudomonas aeruginosa in complex with 2,3-dihydroindol-1-yl-(2-thiophen-3-yl-1,3-thiazol-4- yl)methanone at 2.8a resolution
Source: Pseudomonas aeruginosa. Organism_taxid: 208964. Strain: pao1. Atcc: 47085. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D (233 residues) CATH domain: 3.40.50.720
4bo7
Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (fabg) from pseudomonas aeruginosa in complex with n-(2,3-dihydro-1h-inden-5-yl)tetrazolo(1,5-b) pyridazin-6-amine at 2.6a resolution
Source: Pseudomonas aeruginosa. Organism_taxid: 208964. Strain: pao1. Atcc: 47085. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D (238 residues) CATH domain: 3.40.50.720
4bo8
Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (fabg) from pseudomonas aeruginosa in complex with 1-(2-amino-4-phenylimidazol-1-yl)-3-(2-fluorophenyl) urea at 2.7a resolution
Source: Pseudomonas aeruginosa. Organism_taxid: 208964. Strain: pao1. Atcc: 47085. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D (236 residues) CATH domain: 3.40.50.720
4bo9
Crystal structure of 3-oxoacyl-(acyl-carrier-protein) reductase (fabg) from pseudomonas aeruginosa in complex with 5-(2-(furan-2-ylmethoxy)phenyl)-2-phenyltetrazole at 2.9a resolution
Source: Pseudomonas aeruginosa. Organism_taxid: 208964. Strain: pao1. Atcc: 47085. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D (235 residues) CATH domain: 3.40.50.720
4da9
Crystal structure of putative short-chain dehydrogenase/redu sinorhizobium meliloti 1021
Source: Sinorhizobium meliloti. Organism_taxid: 266834. Strain: 1021. Gene: r03296, smc04391. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D (219 residues) CATH domain: 3.40.50.720
4di7
Structure of a2-type ketoreductase of modular polyketide syn
Source: Streptomyces nodosus. Organism_taxid: 40318. Strain: streptomyces nodosus. Gene: amphb, amphi. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chain: A (477 residues) CATH domain: Unassigned
4dml
3-oxoacyl-[acyl-carrier-protein] reductase from synechococcu elongatus pcc 7942
Source: Synechococcus elongatus. Organism_taxid: 1140. Strain: pcc 7942. Gene: synpcc7942_0684. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (241 residues) CATH domain: 3.40.50.720
4dmm
3-oxoacyl-[acyl-carrier-protein] reductase from synechococcu elongatus pcc 7942 in complex with NADP
Source: Synechococcus elongatus. Organism_taxid: 1140. Strain: pcc 7942. Gene: synpcc7942_0684. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (246 residues) CATH domain: 3.40.50.720
4dry
The crystal structure of 3-oxoacyl-[acyl-carrier-protein] re from rhizobium meliloti
Source: Sinorhizobium meliloti. Rhizobium meliloti. Organism_taxid: 266834. Strain: 1021. Gene: rb1369, sm_b20662. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (241 residues) CATH domain: 3.40.50.720
4fd3
Crystal structure of apo-formed ymtoar1
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: oar1, ykl055c. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D, E, F (254 residues) CATH domain: 3.40.50.720
4fda
Crystal structure of saccharomyces cerevisiae 3-oxoacyl-[acy protein] reductase complexed with NADP
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: oar1, ykl055c. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (243 residues) CATH domain: 3.40.50.720
4fw8
Crystal structure of fabg4 complexed with coenzyme nadh
Source: Mycobacterium tuberculosis. Organism_taxid: 83332. Strain: h37rv. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (427 residues) CATH domains: Unassigned 3.40.50.720
4gkb
Crystal structure of a short chain dehydrogenase homolog (ta 505321) from burkholderia multivorans, unliganded structure
Source: Burkholderia multivorans. Organism_taxid: 395019. Strain: atcc 17616. Gene: bmulj_04919, bmul_3598, fabg. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (247 residues) CATH domain: 3.40.50.720
4glo
Crystal structure of a short chain dehydrogenase homolog (ta 505321) from burkholderia multivorans, with bound NAD
Source: Burkholderia multivorans. Organism_taxid: 395019. Strain: atcc 17616. Gene: fabg, bmul_3598, bmulj_04919. Expressed in: escherichia coli. Expression_system_taxid: 562.
Chains: A, B, C, D (258 residues) CATH domain: 3.40.50.720
4gvx
Crystal structure of a short chain dehydrogenase homolog (ta 505321) from burkholderia multivorans, with bound NADP and
Source: Burkholderia multivorans. Organism_taxid: 395019. Strain: atcc 17616. Gene: bmulj_04919, bmul_3598, fabg. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D (258 residues) CATH domain: 3.40.50.720
4hbg
Crystal structure of saccharomyces cerevisiae 3 oxoacyl-[acy protein]-reductase complexed with NADPH (form2)
Source: Saccharomyces cerevisiae. Baker's yeast. Organism_taxid: 559292. Strain: atcc 204508 / s288c. Gene: oar1, ykl055c. Expressed in: escherichia coli. Expression_system_taxid: 562
Chain: A (257 residues) CATH domain: 3.40.50.720
4i08
Crystal structure of beta-ketoacyl-acyl carrier protein redu (fabg) from vibrio cholerae in complex with NADPH
Source: Vibrio cholerae o1. Organism_taxid: 243277. Strain: atcc 39315 / el tor inaba n16961. Gene: fabg, vc2021, vc_2021. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (243 residues) CATH domain: 3.40.50.720
4iin
Crystal structure of a putative 3-oxoacyl-[acyl-carrier protein]reductase from helicobacter pylori 26695 complexed
Source: Helicobacter pylori. Organism_taxid: 85962. Strain: atcc 700392 / 26695. Gene: hp0561, hp_0561. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D (236 residues) CATH domain: 3.40.50.720
4iiu
Crystal structure of a putative 3-oxoacyl-[acyl-carrier protein]reductase from escherichia coli strain cft073 compl NADP+ at 2.1 a resolution
Source: Escherichia coli. Organism_taxid: 199310. Strain: cft073 / atcc 700928 / upec. Gene: c1187, nt04ec1225. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D (243 residues) CATH domain: 3.40.50.720
4iiv
Crystal structure of a putative 3-oxoacyl-[acyl-carrier protein]reductase from escherichia coli strain cft073 compl NADP+ at 2.5 a resolution
Source: Escherichia coli. Organism_taxid: 199310. Strain: cft073 / atcc 700928 / upec. Gene: c1187, nt04ec1225. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D (242 residues) CATH domain: 3.40.50.720
4ijk
Crystal structure of a putative 3-oxoacyl-[acyl-carrier protein]reductase from helicobacter pylori 26695
Source: Helicobacter pylori. Organism_taxid: 85962. Strain: atcc 700392 / 26695. Gene: hp0561, hp_0561. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B, C, D (236 residues) CATH domain: 3.40.50.720
4kms
Crystal structure of acetoacetyl-coa reductase from ricketts
Source: Rickettsia felis. Organism_taxid: 315456. Strain: atcc vr-1525 / urrwxcal2. Gene: phbb, rf_015, rf_0153. Expressed in: escherichia coli. Expression_system_taxid: 469008.
Chains: A, B (236 residues) CATH domain: 3.40.50.720
4kzp
Crystal structure of a putative short chain dehydrogenase fr mycobacterium smegmatis
Source: Mycobacterium smegmatis. Organism_taxid: 246196. Strain: atcc 700084 / mc(2)155. Gene: msmeg_5903, msmei_5743. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D (291 residues) CATH domain: 3.40.50.720
Bound ligand:   Het Group GOL is 55.56% similar to enzyme reactant (3R)-3-hydroxyacyl-[acyl-carrier-protein]
4nbt
Crystal structure of fabg from acholeplasma laidlawii
Source: Acholeplasma laidlawii. Organism_taxid: 441768. Strain: pg-8a. Gene: fabg2, acl_0504. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B, C, D (239 residues) CATH domain: Unassigned
4nbv
Crystal structure of fabg from cupriavidus taiwanensis
Source: Cupriavidus taiwanensis. Organism_taxid: 164546. Strain: r1 / lmg 19424. Gene: ralta_a2639. Expressed in: escherichia coli. Expression_system_taxid: 562
Chains: A, B (246 residues) CATH domain: 3.40.50.720
4piv
Human fatty acid synthase psi/kr tri-domain with NADPH and g
Source: Homo sapiens. Human. Organism_taxid: 9606. Gene: fasn, fas. Expressed in: spodoptera frugiperda. Expression_system_taxid: 7108.
Chains: A, B (610 residues)
Bound ligand:   Het Group NDP is 50.00% similar to enzyme reactant acetyl-CoA